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Select item 108741021.

Impaired motor unit recovery and maintenance in a knock-in mouse model of ALS-associated Kif5a variant

Kelly A. Rich, Megan G. Pino, Mehmet E. Yalvac, Ashley Fox, Hallie Harris, Maria H. H. Balch, W. David Arnold, Stephen J. Kolb

Neurobiol Dis. Author manuscript; available in PMC 2024 Feb 17.

Published in final edited form as: Neurobiol Dis. 2023 Jun 15; 182: 106148. Published online 2023 May 8. doi: 10.1016/j.nbd.2023.106148

PMCID:: PMC10874102

Article PDF–1.6M

Select item 103179812.

Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA_A receptor transport in a murine model

Jing Liu, Pingyang Ke, Haokun Guo, Juan Gu, Yan Liu, Xin Tian, Xuefeng Wang, Fei Xiao

Exp Mol Med. 2023 Jun; 55(6): 1159–1173. Published online 2023 Jun 1. doi: 10.1038/s12276-023-01000-5

PMCID:: PMC10317981

Article PDF–5.9M

Select item 93226613.

An ALS‐associated KIF5A mutant forms oligomers and aggregates and induces neuronal toxicity

Juri Nakano, Kyoko Chiba, Shinsuke Niwa

Genes Cells. 2022 Jun; 27(6): 421–435. Published online 2022 May 20. doi: 10.1111/gtc.12936

PMCID:: PMC9322661

Article PDF–4.7M

Select item 89477664.

Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration

Sahil H Shah, Lucio M Schiapparelli, Yuanhui Ma, Satoshi Yokota, Melissa Atkins, Xin Xia, Evan G Cameron, Thanh Huang, Sarah Saturday, Catalina B Sun, Cara Knasel, Seth Blackshaw, John R Yates, Hollis T Cline, Jeffrey L Goldberg

eLife. 2022; 11: e68148. Published online 2022 Mar 8. doi: 10.7554/eLife.68148

PMCID:: PMC8947766

Article PDF–6.3M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Article PDF–1.6M

Select item 80787666.

KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity

Mengyu Liu, Huifeng Pi, Yu Xi, Liting Wang, Li Tian, Mengyan Chen, Jia Xie, Ping Deng, Tao Zhang, Chao Zhou, Yidan Liang, Lei Zhang, Mindi He, Yonghui Lu, Chunhai Chen, Zhengping Yu, Zhou Zhou

Autophagy. 2021; 17(4): 903–924. Published online 2020 Mar 30. doi: 10.1080/15548627.2020.1739444

PMCID:: PMC8078766

Article PDF–5.6M

Select item 79453327.

Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport

Xu-Qiao Chen, Utpal Das, Gooho Park, William C. Mobley

Alzheimers Res Ther. 2021; 13: 59. Published online 2021 Mar 10. doi: 10.1186/s13195-021-00796-6

PMCID:: PMC7945332

Article PDF–2.9M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

Select item 70283689.

Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

Junjun Zhao, Albert Hiu Ka Fok, Ruolin Fan, Pui-Yi Kwan, Hei-Lok Chan, Louisa Hoi-Ying Lo, Ying-Shing Chan, Wing-Ho Yung, Jiandong Huang, Cora Sau Wan Lai, Kwok-On Lai

eLife. 2020; 9: e53456. Published online 2020 Jan 21. doi: 10.7554/eLife.53456

PMCID:: PMC7028368

Article PDF–5.0M

Select item 693670810.

Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease

Sumantra Chatterjee, Priyanka Nandakumar, Dallas R. Auer, Stacey B. Gabriel, Aravinda Chakravarti

Proc Natl Acad Sci U S A. 2019 Dec 26; 116(52): 26697–26708. Published online 2019 Dec 9. doi: 10.1073/pnas.1908756116

PMCID:: PMC6936708

Article PDF–2.1M

Select item 687358811.

Postsynaptic density protein 95 (PSD-95) is transported by KIF5 to dendritic regions

Ki-Seo Yoo, Kina Lee, Jun-Young Oh, Hyoeun Lee, Hyungju Park, Young Seok Park, Hyong Kyu Kim

Mol Brain. 2019; 12: 97. Published online 2019 Nov 21. doi: 10.1186/s13041-019-0520-x

PMCID:: PMC6873588

Article PDF–3.6M

Select item 677294812.

KIF5C, a Novel Neuronal Kinesin Enriched in Motor Neurons

Yoshimitsu Kanai, Yasushi Okada, Yosuke Tanaka, Akihiro Harada, Sumio Terada, Nobutaka Hirokawa

J Neurosci. 2000 Sep 1; 20(17): 6374–6384. doi: 10.1523/JNEUROSCI.20-17-06374.2000

PMCID:: PMC6772948

Article PDF–1.6M

Select item 675851613.

Identification of Quantitative Trait Loci That Affect Aggressive Behavior in Mice

Edward S. Brodkin, Sarah A. Goforth, Angela H. Keene, John A. Fossella, Lee M. Silver

J Neurosci. 2002 Feb 1; 22(3): 1165–1170. doi: 10.1523/JNEUROSCI.22-03-01165.2002

PMCID:: PMC6758516

Article PDF–126K

Select item 615841914.

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons

Grayson DuRaine, Todd W. Wisner, Paul Howard, David C. Johnson

J Virol. 2018 Oct 15; 92(20): e01269-18. Prepublished online 2018 Aug 1. Published online 2018 Sep 26. doi: 10.1128/JVI.01269-18

PMCID:: PMC6158419

Article PDF–1.5M

Select item 564508215.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Article PDF–2.3M

Select item 559832116.

Spatiotemporally Controlled Ablation of Klf5 Results in Dysregulated Epithelial Homeostasis in Adult Mouse Corneas

Chelsea L. Loughner, Anil Tiwari, Doreswamy Kenchegowda, Sudha Swamynathan, Shivalingappa K. Swamynathan

Invest Ophthalmol Vis Sci. 2017 Sep; 58(11): 4683–4693. doi: 10.1167/iovs.17-22498

PMCID:: PMC5598321

Article PDF–3.0M

Select item 549686917.

KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis

Hirotoshi Kamata, Yoshikazu Tsukasaki, Tsuyoshi Sakai, Reiko Ikebe, Julia Wang, Ann Jeffers, Jake Boren, Shuzi Owens, Takahiro Suzuki, Masaaki Higashihara, Steven Idell, Torry A. Tucker, Mitsuo Ikebe

Sci Rep. 2017; 7: 4556. Published online 2017 Jul 4. doi: 10.1038/s41598-017-04437-7

PMCID:: PMC5496869

Article PDF–2.3M

Select item 538122618.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Article PDF–1.4M

Select item 503924619.

Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport

Mathew A. Sherman, Michael LaCroix, Fatou Amar, Megan E. Larson, Colleen Forster, Adriano Aguzzi, David A. Bennett, Martin Ramsden, Sylvain E. Lesné

J Neurosci. 2016 Sep 14; 36(37): 9647–9658. doi: 10.1523/JNEUROSCI.1899-16.2016

PMCID:: PMC5039246

Article PDF–2.6M

Select item 440175420.

Analysis of Kif5b Expression during Mouse Kidney Development

Ju Cui, Xiuling Li, Zhigang Duan, Wenqian Xue, Zai Wang, Song Lu, Raozhou Lin, Mengfei Liu, Guixia Zhu, Jian-Dong Huang

PLoS One. 2015; 10(4): e0126002. Published online 2015 Apr 17. doi: 10.1371/journal.pone.0126002

PMCID:: PMC4401754

Article PDF–4.6M

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