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Select item 107345501.

Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

Nikhil Sharma, Patricia Kessler, Ganes C. Sen

J Virol. 2023 Dec; 97(12): e01304-23. Published online 2023 Nov 20. doi: 10.1128/jvi.01304-23

PMCID:: PMC10734550

Article PDF–913K

Select item 92185152.

PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c

Asli E. Dogan, Syed M. Hamid, Asli D. Yildirim, Zehra Yildirim, Ganes Sen, Celine E. Riera, Roberta A. Gottlieb, Ebru Erbay

J Biol Chem. 2022 Jul; 298(7): 102050. Published online 2022 May 19. doi: 10.1016/j.jbc.2022.102050

PMCID:: PMC9218515

Article PDF–1.2M

Select item 79486453.

Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells

Chandan Gurung, Mona Fendereski, Krishna Sapkota, Jason Guo, Faqing Huang, Yan-Lin Guo

J Biol Chem. 2021 Jan-Jun; 296: 100264. Published online 2021 Jan 8. doi: 10.1016/j.jbc.2021.100264

PMCID:: PMC7948645

Article PDF–1.7M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

Select item 79199475.

Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling

Lauren S. Vaughn, Evelyn Chukwurah, Rekha C Patel

Biochem J. Author manuscript; available in PMC 2022 Feb 12.

Published in final edited form as: Biochem J. 2021 Feb 12; 478(3): 493–510. doi: 10.1042/BCJ20200987

PMCID:: PMC7919947

Article PDF–1.6M

Select item 78487496.

A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells

Kazuhiro Murakami, Yumi Terakado, Kikue Saito, Yoshie Jomen, Haruna Takeda, Masanobu Oshima, Nick Barker

Proc Natl Acad Sci U S A. 2021 Jan 26; 118(4): e2016806118. Published online 2021 Jan 21. doi: 10.1073/pnas.2016806118

PMCID:: PMC7848749

Article PDF–3.2M

Select item 66927707.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Article PDF–7.7M

Select item 66023008.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Article

Select item 59684039.

PKR modulates abnormal brain signaling in experimental obesity

Mariko Taga, François Mouton-Liger, Malha Sadoune, Sarah Gourmaud, Jenny Norman, Marion Tible, Sylvie Thomasseau, Claire Paquet, James A. R. Nicoll, Delphine Boche, Jacques Hugon

PLoS One. 2018; 13(5): e0196983. Published online 2018 May 24. doi: 10.1371/journal.pone.0196983

PMCID:: PMC5968403

Article PDF–15M

Select item 588714510.

Functional Redundancy of DICER Cofactors TARBP2 and PRKRA During Murine Embryogenesis Does Not Involve miRNA Biogenesis

Sri Ramulu N. Pullagura, Bill Buaas, Nichelle Gray, Lindsey C. Krening, Anuj Srivastava, Robert E. Braun

Genetics. 2018 Apr; 208(4): 1513–1522. Published online 2018 Feb 21. doi: 10.1534/genetics.118.300791

PMCID:: PMC5887145

Article PDF–1.3M

Select item 473361611.

Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology

Kristina Palmer, Heather Fairfield, Suhaib Borgeia, Michelle Curtain, Mohamed G. Hassan, Louise Dionne, Son Yong Karst, Harold Coombs, Laura G. Reinholdt, David E. Bergstrom, Leah Rae Donahue, Timothy C. Cox, Stephen A. Murray

Dev Biol. Author manuscript; available in PMC 2017 Jul 15.

Published in final edited form as: Dev Biol. 2016 Jul 15; 415(2): 216–227. Published online 2015 Jul 31. doi: 10.1016/j.ydbio.2015.07.023

PMCID:: PMC4733616

Article PDF–827K

Select item 471552012.

The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

Benjamin K. Dickerman, Christine L. White, Patricia M. Kessler, Anthony J. Sadler, Bryan R.G. Williams, Ganes C. Sen

FEBS J. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: FEBS J. 2015 Dec; 282(24): 4766–4781. Published online 2015 Oct 26. doi: 10.1111/febs.13533

PMCID:: PMC4715520

Article PDF–2.1M

Select item 465392513.

PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load

David Chun-Hei Poon, Yuen-Shan Ho, Ran You, Hei-Long Tse, Kin Chiu, Raymond Chuen-Chung Chang

J Neuroinflammation. 2015; 12: 212. Published online 2015 Nov 19. doi: 10.1186/s12974-015-0433-2

PMCID:: PMC4653925

Article PDF–1.5M

Select item 448439214.

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders

Heather Fairfield, Anuj Srivastava, Guruprasad Ananda, Rangjiao Liu, Martin Kircher, Anuradha Lakshminarayana, Belinda S. Harris, Son Yong Karst, Louise A. Dionne, Coleen C. Kane, Michelle Curtain, Melissa L. Berry, Patricia F. Ward-Bailey, Ian Greenstein, Candice Byers, Anne Czechanski, Jocelyn Sharp, Kristina Palmer, Polyxeni Gudis, Whitney Martin, Abby Tadenev, Laurent Bogdanik, C. Herbert Pratt, Bo Chang, David G. Schroeder, Gregory A. Cox, Paul Cliften, Jeffrey Milbrandt, Stephen Murray, Robert Burgess, David E. Bergstrom, Leah Rae Donahue, Hanan Hamamy, Amira Masri, Federico A. Santoni, Periklis Makrythanasis, Stylianos E. Antonarakis, Jay Shendure, Laura G. Reinholdt

Genome Res. 2015 Jul; 25(7): 948–957. doi: 10.1101/gr.186882.114

PMCID:: PMC4484392

Article PDF–604K

Select item 430232215.

PACT/RAX Regulates the Migration of Cerebellar Granule Neurons in the Developing Cerebellum

Yue Yong, Ya Meng, Hanqing Ding, Zhiqin Fan, Yifen Tang, Chenghua Zhou, Jia Luo, Zun-Ji Ke

Sci Rep. 2015; 5: 7961. Published online 2015 Jan 22. doi: 10.1038/srep07961

PMCID:: PMC4302322

Article PDF–8.8M

Select item 402619816.

Essential Role of PACT-Mediated PKR Activation in Tunicamycin-induced Apoptosis

Madhurima Singh, Vennese Fowlkes, Indhira Handy, Chandrashekhar V. Patel, Rekha C. Patel

J Mol Biol. Author manuscript; available in PMC 2014 May 19.

Published in final edited form as: J Mol Biol. 2009 Jan 16; 385(2): 457–468. Published online 2008 Nov 5. doi: 10.1016/j.jmb.2008.10.068

PMCID:: PMC4026198

Article PDF–2.2M

Select item 375754317.

The Protein Kinase PKR is Critical for LPS-induced iNOS Production, but Dispensable for Inflammasome Activation in Macrophages

Yuan He, Luigi Franchi, Gabriel Núñez

Eur J Immunol. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Eur J Immunol. 2013 May; 43(5): 1147–1152. Published online 2013 Mar 15. doi: 10.1002/eji.201243187

PMCID:: PMC3757543

Article PDF–2.3M

Select item 374995918.

The Protein Kinase Double-Stranded RNA-Dependent (PKR) Enhances Protection against Disease Cause by a Non-Viral Pathogen

Pauline Sebby Ogolla, Jose-Andres C. Portillo, Christine L. White, Krupen Patel, Bruce Lamb, Ganes C. Sen, Carlos S. Subauste

PLoS Pathog. 2013 Aug; 9(8): e1003557. Published online 2013 Aug 22. doi: 10.1371/journal.ppat.1003557

PMCID:: PMC3749959

Article PDF–6.4M

Select item 365189419.

ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing

Hiromitsu Ota, Masayuki Sakurai, Ravi Gupta, Louis Valente, Bjorn-Erik Wulff, Kentaro Ariyoshi, Hisashi Iizasa, Ramana V. Davuluri, Kazuko Nishikura

Cell. Author manuscript; available in PMC 2014 Apr 25.

Published in final edited form as: Cell. 2013 Apr 25; 153(3): 575–589. doi: 10.1016/j.cell.2013.03.024

PMCID:: PMC3651894

Article PDF–4.6M

Select item 330804920.

Mutation discovery in mice by whole exome sequencing

Heather Fairfield, Griffith J Gilbert, Mary Barter, Rebecca R Corrigan, Michelle Curtain, Yueming Ding, Mark D'Ascenzo, Daniel J Gerhardt, Chao He, Wenhui Huang, Todd Richmond, Lucy Rowe, Frank J Probst, David E Bergstrom, Stephen A Murray, Carol Bult, Joel Richardson, Benjamin T Kile, Ivo Gut, Jorg Hager, Snaevar Sigurdsson, Evan Mauceli, Federica Di Palma, Kerstin Lindblad-Toh, Michael L Cunningham, Timothy C Cox, Monica J Justice, Mona S Spector, Scott W Lowe, Thomas Albert, Leah Rae Donahue, Jeffrey Jeddeloh, Jay Shendure, Laura G Reinholdt

Genome Biol. 2011; 12(9): R86. Published online 2011 Sep 14. doi: 10.1186/gb-2011-12-9-r86

PMCID:: PMC3308049

Article PDF–1.2M

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