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Select item 90145591.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Article PDF–6.6M

Select item 83132392.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Article PDF–1.6M

Select item 67454993.

TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity

Wenting Zhu, Jiaxin Li, Rui Zhang, Yixiang Cai, Changwan Wang, Shishi Qi, She Chen, Xiaozhen Liang, Nan Qi, Fajian Hou

EMBO J. 2019 Sep 16; 38(18): e102075. Published online 2019 Aug 7. doi: 10.15252/embj.2019102075

PMCID:: PMC6745499

Article PDF–2.3M

Select item 65414644.

Control of antiviral innate immune response by protein geranylgeranylation

Shigao Yang, Alfred T. Harding, Catherine Sweeney, David Miao, Gregory Swan, Connie Zhou, Zhaozhao Jiang, Katherine A. Fitzgerald, Gianna Hammer, Martin O. Bergo, Heather K. Kroh, D. Borden Lacy, Chunxiang Sun, Michael Glogauer, Loretta G. Que, Nicholas S. Heaton, Donghai Wang

Sci Adv. 2019 May; 5(5): eaav7999. Published online 2019 May 29. doi: 10.1126/sciadv.aav7999

PMCID:: PMC6541464

Article PDF–2.7M

Select item 64619195.

RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development

Holly Anderton, Esther Bandala-Sanchez, Daniel S Simpson, James A Rickard, Ashley P Ng, Ladina Di Rago, Cathrine Hall, James E Vince, John Silke, Gianmaria Liccardi, Rebecca Feltham

Cell Death Differ. 2019 May; 26(5): 877–889. Published online 2018 Sep 5. doi: 10.1038/s41418-018-0166-8

PMCID:: PMC6461919

Article PDF–6.5M

Select item 63708796.

TRADD regulates perinatal development and adulthood survival in mice lacking RIPK1 and RIPK3

John P. Dowling, Mohamed Alsabbagh, Christina Del Casale, Zheng-Gang Liu, Jianke Zhang

Nat Commun. 2019; 10: 705. Published online 2019 Feb 11. doi: 10.1038/s41467-019-08584-5

PMCID:: PMC6370879

Article PDF–1.8M

Select item 63529247.

Tumour necrosis factor signalling in health and disease

Jonathan Holbrook, Samuel Lara-Reyna, Heledd Jarosz-Griffiths, Michael F. McDermott

Version 1. F1000Res. 2019; 8: F1000 Faculty Rev-111. Published online 2019 Jan 28. doi: 10.12688/f1000research.17023.1

PMCID:: PMC6352924

Article PDF–1.8M

Select item 57295358.

MOMP, cell suicide as a BCL-2 family business

Halime Kalkavan, Douglas R Green

Cell Death Differ. 2018 Jan; 25(1): 46–55. Published online 2017 Oct 20. doi: 10.1038/cdd.2017.179

PMCID:: PMC5729535

Article PDF–1.3M

Select item 55012529.

SYK licenses MyD88 to instigate IL-1α-mediated inflammatory disease

Prajwal Gurung, Gaofeng Fan, John R. Lukens, Peter Vogel, Nicholas K Tonks, Thirumala-Devi Kanneganti

Immunity. Author manuscript; available in PMC 2018 Apr 18.

Published in final edited form as: Immunity. 2017 Apr 18; 46(4): 635–648. Published online 2017 Apr 11. doi: 10.1016/j.immuni.2017.03.014

PMCID:: PMC5501252

Article PDF–1.1M

Select item 544507210.

Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression

Aimilios Kaklamanos, Jan Rozman, Manolis Roulis, Niki Karagianni, Maria Armaka, Moya Wu, Laura Brachthäuser, Julia Calzada-Wack, Marion Horsch, Johannes Beckers, Birgit Rathkolb, Thure Adler, Frauke Neff, Eckhard Wolf, Valerie Gailus-Durner, Helmut Fuchs, Martin Hrabe de Angelis, George Kollias

Sci Rep. 2017; 7: 2397. Published online 2017 May 25. doi: 10.1038/s41598-017-02581-8

PMCID:: PMC5445072

Article PDF–6.2M

Select item 534152011.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Article PDF–1.1M

Select item 513192412.

ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways

Teneema Kuriakose, Si Ming Man, R.K. Subbarao Malireddi, Rajendra Karki, Sannula Kesavardhana, David E. Place, Geoffrey Neale, Peter Vogel, Thirumala-Devi Kanneganti

Sci Immunol. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Sci Immunol. 2016 Aug 5; 1(2): aag2045. Published online 2016 Aug 12. doi: 10.1126/sciimmunol.aag2045

PMCID:: PMC5131924

Article PDF–2.2M

Select item 476886513.

Maternal Hyperglycemia Activates an ASK1–FoxO3a–Caspase 8 Pathway That Leads to Embryonic Neural Tube Defects

Peixin Yang, Xuezheng Li, Cheng Xu, Richard L. Eckert, E. Albert Reece, Horst Ronald Zielke, Fang Wang

Sci Signal. Author manuscript; available in PMC 2016 Feb 26.

Published in final edited form as: Sci Signal. 2013 Aug 27; 6(290): ra74. Published online 2013 Aug 27. doi: 10.1126/scisignal.2004020

PMCID:: PMC4768865

Article PDF–675K

Select item 472813314.

The REST remodeling complex protects genomic integrity during embryonic neurogenesis

Tamilla Nechiporuk, James McGann, Karin Mullendorff, Jenny Hsieh, Wolfgang Wurst, Thomas Floss, Gail Mandel

eLife. 2016; 5: e09584. Published online 2016 Jan 8. doi: 10.7554/eLife.09584

PMCID:: PMC4728133

Article PDF–8.3M

Select item 464422115.

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

Vangelis Kondylis, Apostolos Polykratis, Hanno Ehlken, Laura Ochoa-Callejero, Beate Katharina Straub, Santosh Krishna-Subramanian, Trieu-My Van, Harald-Morten Curth, Nicole Heise, Falk Weih, Ulf Klein, Peter Schirmacher, Michelle Kelliher, Manolis Pasparakis

Cancer Cell. 2015 Nov 9; 28(5): 582–598. doi: 10.1016/j.ccell.2015.10.001

Correction in:: Cancer Cell. 2015 Dec 14; 28(6): 830.

PMCID:: PMC4644221

Article

Select item 422549116.

Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis

Snehlata Kumari, Younes Redouane, Jaime Lopez-Mosqueda, Ryoko Shiraishi, Malgorzata Romanowska, Stefan Lutzmayer, Jan Kuiper, Conception Martinez, Ivan Dikic, Manolis Pasparakis, Fumiyo Ikeda

eLife. 2014; 3: e03422. Published online 2014 Dec 2. doi: 10.7554/eLife.03422