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Select item 108447451.

Nur77 mitigates endothelial dysfunction through activation of both nitric oxide production and anti-oxidant pathways

Lin Lu, Soohwa Jang, Jiaqi Zhu, Qing Qin, Lijun Sun, Jianxin Sun

Redox Biol. 2024 Apr; 70: 103056. Published online 2024 Jan 24. doi: 10.1016/j.redox.2024.103056

PMCID:: PMC10844745

Article PDF–6.1M

Select item 107539512.

Gut Commensal Segmented Filamentous Bacteria Fine-Tune T Follicular Regulatory Cells to Modify the Severity of Systemic Autoimmune Arthritis

Nicholas A. Bates, Anna Li, Tingting Fan, Madeline P. Cutcliffe, Caitlyn B. Dagenet, Kiah C. Sleiman, Heqing Ma, Shekha Tahsin, Candace S. Garrett, Jesse Altemus, Hsin-Jung Joyce Wu

J Immunol. Author manuscript; available in PMC 2023 Dec 28.

Published in final edited form as: J Immunol. 2021 Mar 1; 206(5): 941–952. Published online 2021 Jan 18. doi: 10.4049/jimmunol.2000663

PMCID:: PMC10753951

Article PDF–2.4M

Select item 105881163.

NR4A1 deletion promotes pro-angiogenic polarization of macrophages derived from classical monocytes in a mouse model of neovascular age-related macular degeneration

Steven Droho, Andrew P. Voigt, Jacob K. Sterling, Amrita Rajesh, Kyle S. Chan, Carla M. Cuda, Harris Perlman, Jeremy A. Lavine

J Neuroinflammation. 2023; 20: 238. Published online 2023 Oct 19. doi: 10.1186/s12974-023-02928-1

PMCID:: PMC10588116

Article PDF–7.4M

Select item 105762904.

Nr4a1 marks a distinctive ILC2 activation subset in the mouse inflammatory lung

Shasha Xu, Yu Zhang, Xingjie Liu, Huisheng Liu, Xinya Zou, Linlin Zhang, Jing Wang, Zhiwei Zhang, Xiang Xu, Mingxia Li, Kairui Li, Shuyue Shi, Ying Zhang, Zhichao Miao, Jie Zha, Yong Yu

BMC Biol. 2023; 21: 218. Published online 2023 Oct 13. doi: 10.1186/s12915-023-01690-3

PMCID:: PMC10576290

Article PDF–14M

Select item 103653145.

Noncanonical contribution of microglial transcription factor NR4A1 to post-stroke recovery through TNF mRNA destabilization

Pinyi Liu, Yan Chen, Zhi Zhang, Zengqiang Yuan, Jian-Guang Sun, Shengnan Xia, Xiang Cao, Jian Chen, Cun-Jin Zhang, Yanting Chen, Hui Zhan, Yuexinzi Jin, Xinyu Bao, Yue Gu, Meijuan Zhang, Yun Xu

PLoS Biol. 2023 Jul; 21(7): e3002199. Published online 2023 Jul 24. doi: 10.1371/journal.pbio.3002199

PMCID:: PMC10365314

Article PDF–3.9M

Select item 102834996.

Dexmedetomidine attenuates inflammation and organ injury partially by upregulating Nur77 in sepsis

Qian Zhang, Yun Huang, Chenchen Gong, Yan Tang, Jie Xiong, Difen Wang, Xu Liu

Immun Inflamm Dis. 2023 Jun; 11(6): e883. Published online 2023 Jun 21. doi: 10.1002/iid3.883

PMCID:: PMC10283499

Article PDF–2.3M

Select item 101932317.

Alternatively activated lung alveolar and interstitial macrophages promote fungal growth

Ashley B. Strickland, Yanli Chen, Donglei Sun, Meiqing Shi

iScience. 2023 May 19; 26(5): 106717. Published online 2023 Apr 23. doi: 10.1016/j.isci.2023.106717

PMCID:: PMC10193231

Article PDF–6.1M

Select item 101866068.

Oxidative stress impairs the Nur77‐Sirt1 axis resulting in a decline in organism homeostasis during aging

Yang Yu, Xiaoyu Song, Xiaoxun Wang, Lixia Zheng, Guojing Ma, Weiwei Liu, Han Su, Xiyan Liu, Tingting Liu, Liu Cao, Difei Wang

Aging Cell. 2023 May; 22(5): e13812. Published online 2023 Mar 7. doi: 10.1111/acel.13812

PMCID:: PMC10186606

Article PDF–43M

Select item 101694529.

Nr4a1 promotes renal interstitial fibrosis by regulating the p38 MAPK phosphorylation

Yilin Tao, Chengyuan Tang, Ju Wei, Yi Shan, Xi Fang, Ying Li

Mol Med. 2023; 29: 63. Published online 2023 May 9. doi: 10.1186/s10020-023-00657-y

PMCID:: PMC10169452

Article PDF–2.3M

Select item 1015421110.

MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation

Domien Vanneste, Qiang Bai, Shakir Hasan, Wen Peng, Dimitri Pirottin, Joey Schyns, Pauline Maréchal, Cecilia Ruscitti, Margot Meunier, Zhaoyuan Liu, Céline Legrand, Laurence Fievez, Florent Ginhoux, Coraline Radermecker, Fabrice Bureau, Thomas Marichal

Nat Immunol. 2023; 24(5): 827–840. Published online 2023 Mar 16. doi: 10.1038/s41590-023-01468-3

PMCID:: PMC10154211

Article PDF–12M

Select item 989095711.

Nr4a1-dependent non-classical monocytes are important for macrophage-mediated wound healing in the large intestine

Karin Heidbreder, Katrin Sommer, Maximilian Wiendl, Tanja M. Müller, Imke Atreya, Kai Hildner, Markus F. Neurath, Sebastian Zundler

Front Immunol. 2022; 13: 1040775. Published online 2023 Jan 18. doi: 10.3389/fimmu.2022.1040775

PMCID:: PMC9890957

Article PDF–4.9M

Select item 984122912.

Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice

Xinyu Cai, Yue Jiang, Zhiwen Cao, Mei Zhang, Na Kong, Lina Yu, Yedong Tang, Shuangbo Kong, Wenbo Deng, Haibin Wang, Jianxin Sun, Lijun Ding, Ruiwei Jiang, Haixiang Sun, Guijun Yan

eBioMedicine. 2023 Feb; 88: 104433. Published online 2023 Jan 7. doi: 10.1016/j.ebiom.2022.104433

PMCID:: PMC9841229

Article PDF–3.2M

Select item 958460613.

A novel monocyte differentiation pattern in pristane-induced lupus with diffuse alveolar hemorrhage

Shuhong Han, Haoyang Zhuang, Rawad Daniel Arja, Westley H Reeves

eLife. 2022; 11: e76205. Published online 2022 Oct 20. doi: 10.7554/eLife.76205

PMCID:: PMC9584606

Article PDF–10M

Select item 934325314.

Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex

Wen Yuan, Sai Ma, Juliana R. Brown, Kwanho Kim, Vanessa Murek, Lucia Trastulla, Alexander Meissner, Simona Lodato, Ashwin S. Shetty, Joshua Z. Levin, Jason D. Buenrostro, Michael J. Ziller, Paola Arlotta

Nat Neurosci. 2022; 25(8): 1049–1058. Published online 2022 Aug 1. doi: 10.1038/s41593-022-01123-4

PMCID:: PMC9343253

Article PDF–17M

Select item 922654915.

Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages

Qianqian Li, Yutian Li, Wei Huang, Xiaohong Wang, Zhenling Liu, Jing Chen, Yanbo Fan, Tianqing Peng, Sakthivel Sadayappan, Yigang Wang, Guo-Chang Fan

Front Immunol. 2022; 13: 930397. Published online 2022 Jun 10. doi: 10.3389/fimmu.2022.930397

PMCID:: PMC9226549

Article PDF–6.8M

Select item 906400016.

A Bacterial Bile Acid Metabolite Modulates T_reg Activity through the Nuclear Hormone Receptor NR4A1

Wei Li, Saiyu Hang, Yuan Fang, Sena Bae, Yancong Zhang, Minghao Zhang, Gang Wang, Megan D. McCurry, Munhyung Bae, Donggi Paik, Eric A. Franzosa, Fraydoon Rastinejad, Curtis Huttenhower, Lina Yao, A. Sloan Devlin, Jun R. Huh

Cell Host Microbe. Author manuscript; available in PMC 2022 Sep 8.

Published in final edited form as: Cell Host Microbe. 2021 Sep 8; 29(9): 1366–1377.e9. Published online 2021 Aug 19. doi: 10.1016/j.chom.2021.07.013