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Select item 106618261.

A Novel CDC42 Variant with Impaired Thymopoiesis, IL-7R Signaling, PAK1 Binding, and TCR Repertoire Diversity

Kristian Assing, Sofie E. Jørgensen, Katrine S. Sandgaard, Kerstin De Keukeleere, Marie B.-Hansen, Mikkel S. Petersen, Ulla B. Hartling, Thanis M. K.-de Vaal, Christian Nielsen, Marianne A. Jakobsen, Eleanor Watt, Stuart Adams, Qin Hao, Christina Fagerberg, Trine H. Mogensen

J Clin Immunol. 2023; 43(8): 1927–1940. Published online 2023 Aug 15. doi: 10.1007/s10875-023-01561-0

PMCID:: PMC10661826

Abstract Article PDF–4.5M

Select item 103232522.

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell

J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468

PMCID:: PMC10323252

Abstract Article

Select item 102972133.

Spatiotemporal Coordination of Rac1 and Cdc42 at the Whole Cell Level during Cell Ruffling

Siarhei Hladyshau, Jorik P. Stoop, Kosei Kamada, Shuyi Nie, Denis Tsygankov

Cells. 2023 Jun; 12(12): 1638. Published online 2023 Jun 15. doi: 10.3390/cells12121638

PMCID:: PMC10297213

Abstract Article PDF–7.7M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101916265.

ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization

Katarzyna Bogucka-Janczi, Gregory Harms, Marie-May Coissieux, Mohamed Bentires-Alj, Bernd Thiede, Krishnaraj Rajalingam

eLife. 2023; 12: e85167. Published online 2023 Apr 14. doi: 10.7554/eLife.85167

PMCID:: PMC10191626

Abstract Article PDF–30M

Select item 101522376.

circFNDC3B Accelerates Vasculature Formation and Metastasis in Oral Squamous Cell Carcinoma

Xiang Li, Chenxing Wang, Hang Zhang, Yangjie Li, Deqiang Hou, Dingshan Liu, Rongyao Xu, Jie Cheng, Laikui Liu, Yu Fu, Jinhai Ye, Hongbing Jiang

Cancer Res. 2023 May 2; 83(9): 1459–1475. Published online 2023 Feb 22. doi: 10.1158/0008-5472.CAN-22-2585

PMCID:: PMC10152237

Abstract Article PDF–22M

Select item 100926437.

BAG6 supports stress fiber formation by preventing the ubiquitin-mediated degradation of RhoA

Maho Miyauchi, Reina Matsumura, Hiroyuki Kawahara

Mol Biol Cell. 2023 Apr 1; 34(4): ar34. Published online 2023 Mar 17. doi: 10.1091/mbc.E22-08-0355

PMCID:: PMC10092643

Abstract Article PDF–23M

Select item 100145358.

“From molecular to clinic”: The pivotal role of CDC42 in pathophysiology of human papilloma virus related cancers and a correlated sensitivity of afatinib

Erdong Wei, Jiahua Li, Philipp Anand, Lars E. French, Adam Wattad, Benjamin Clanner-Engelshofen, Markus Reinholz

Front Immunol. 2023; 14: 1118458. Published online 2023 Mar 1. doi: 10.3389/fimmu.2023.1118458

PMCID:: PMC10014535

Abstract Article PDF–26M

Select item 99930429.

Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes

Wai Shan Yuen, Qing Hua Zhang, Anne Bourdais, Deepak Adhikari, Guillaume Halet, John Carroll

Open Biol. 2023 Mar; 13(3): 220326. Published online March 8, 2023. doi: 10.1098/rsob.220326

PMCID:: PMC9993042

Abstract Article PDF–2.3M

Select item 997863510.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 995044711.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 983529612.

AFAP1L1 promotes gastric cancer progression by interacting with VAV2 to facilitate CDC42-mediated activation of ITGA5 signaling pathway

Bo Sun, Bai Ding, Yu Chen, Chuang Peng, Xu Chen

J Transl Med. 2023; 21: 18. Published online 2023 Jan 11. doi: 10.1186/s12967-023-03871-8

PMCID:: PMC9835296

Abstract Article PDF–23M

Select item 979483813.

ARHGAP17 regulates the spatiotemporal activity of Cdc42 at invadopodia

Gabriel Kreider-Letterman, Abel Castillo, Eike K. Mahlandt, Joachim Goedhart, Agustin Rabino, Silvia Goicoechea, Rafael Garcia-Mata

J Cell Biol. 2023 Feb 6; 222(2): e202207020. Published online 2022 Dec 26. doi: 10.1083/jcb.202207020

PMCID:: PMC9794838

Abstract Article PDF–11M

Select item 970183914.

Cell division cycle 42 positively correlates with T helper 2 cytokine, effusion viscosity, and hearing loss degree in otitis media with effusion patients

Dan Wu, Yang Yang, Chuanxin Duan

J Clin Lab Anal. 2022 Nov; 36(11): e24681. Published online 2022 Sep 26. doi: 10.1002/jcla.24681

PMCID:: PMC9701839

Abstract Article PDF–4.2M

Select item 955096215.

Cell division cycle 42 reflects disease risk, symptoms, Th1/Th2 disproportion, and its short‐term variation indicates symptom amelioration after treatment in allergic rhinitis patients

Xiaote Zhang, Lujie Xie, Xiaoyun Fang

J Clin Lab Anal. 2022 Oct; 36(10): e24684. Published online 2022 Aug 31. doi: 10.1002/jcla.24684

PMCID:: PMC9550962

Abstract Article PDF–4.3M

Select item 955026616.

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition

Ilaria Iacobucci, Vittoria Monaco, Luisa Canè, Francesca Bibbò, Valentina Cioffi, Flora Cozzolino, Alfredo Guarino, Massimo Zollo, Maria Monti

Front Mol Biosci. 2022; 9: 975570. Published online 2022 Sep 26. doi: 10.3389/fmolb.2022.975570

PMCID:: PMC9550266

Abstract Article PDF–2.5M

Select item 952994717.

Activation of RhoC by regulatory ubiquitination is mediated by LNX1 and suppressed by LIS1

Stanislav Kholmanskikh, Shawn Singh, M. Elizabeth Ross

Sci Rep. 2022; 12: 16493. Published online 2022 Oct 3. doi: 10.1038/s41598-022-19740-1

PMCID:: PMC9529947

Abstract Article PDF–4.9M

Select item 950735718.

Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer

Xiujuan Zhang, Fei Luo, Shaliu Luo, Ling Li, Xinxin Ren, Jing Lin, Yingchun Liang, Chao Ma, Lihua Ding, Deyu Zhang, Tianxing Ye, Yanni Lin, Bilian Jin, Shan Gao, Qinong Ye

Adv Sci (Weinh) 2022 Sep; 9(27): 2200705. Published online 2022 Jul 27. doi: 10.1002/advs.202200705