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Items: 1 to 20 of 486

1.
DNA damage in IDH-mutant gliomas: mechanisms and clinical implications
Diana D. Shi, Soummitra Anand, Kalil G. Abdullah, Samuel K. McBrayer
J Neurooncol. Author manuscript; available in PMC 2024 May 1.
Published in final edited form as: J Neurooncol. 2023 May; 162(3): 515–523. Published online 2022 Nov 9. doi: 10.1007/s11060-022-04172-8
PMCID:
PMC10956168
ArticlePDF–775K
2.
The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen
Tathiane M. Malta, Thais S. Sabedot, Natalia S. Morosini, Indrani Datta, Luciano Garofano, Wies Vallentgoed, Frederick S. Varn, Kenneth Aldape, Fulvio D'Angelo, Spyridon Bakas, Jill S. Barnholtz-Sloan, Hui K. Gan, Mohammad Hasanain, Ann-Christin Hau, Kevin C. Johnson, Simona Cazacu, Ana C. deCarvalho, Mustafa Khasraw, Emre Kocakavuk, Mathilde C.M. Kouwenhoven, Simona Migliozzi, Simone P. Niclou, Johanna M. Niers, D. Ryan Ormond, Sun Ha Paek, Guido Reifenberger, Peter A. Sillevis Smitt, Marion Smits, Lucy F. Stead, Martin J. van den Bent, Erwin G. Van Meir, Annemiek Walenkamp, Tobias Weiss, Michael Weller, Bart A. Westerman, Bauke Ylstra, Pieter Wesseling, Anna Lasorella, Pim J. French, Laila M. Poisson, Consortium The GLASS , Roel G.W. Verhaak, Antonio Iavarone, Houtan Noushmehr
Cancer Res. 2024 Mar 4; 84(5): 741–756. Published online 2023 Dec 20. doi: 10.1158/0008-5472.CAN-23-2093
PMCID:
PMC10911804
ArticlePDF–17M
3.
Cognitive functioning is prognostic in patients with IDH1-wild type and MGMT-unmethylated high-grade gliomas
Uroš Smrdel, Andreja Cirila Škufca Smrdel, Anja Podlesek, Marija Skoblar Vidmar, Gregor Kos, Jana Markovic, Jana Jereb, Jana Knific, Tina Rus
Croat Med J. 2023 Dec; 64(6): 383–390. doi: 10.3325/cmj.2023.64.383
PMCID:
PMC10797236
ArticlePDF–373K
4.
Improved prognostic stratification of patients with isocitrate dehydrogenase-mutant astrocytoma
Michael Weller, Jörg Felsberg, Bettina Hentschel, Dorothee Gramatzki, Nadezhda Kubon, Marietta Wolter, Matthias Reusche, Patrick Roth, Dietmar Krex, Ulrich Herrlinger, Manfred Westphal, Joerg C. Tonn, Luca Regli, Claude-Alain Maurage, Andreas von Deimling, Torsten Pietsch, Emilie Le Rhun, Guido Reifenberger
Acta Neuropathol. 2024; 147(1): 11. Published online 2024 Jan 6. doi: 10.1007/s00401-023-02662-1
PMCID:
PMC10771615
ArticlePDF–2.0M
5.
Genetic Polymorphism Study of IDH 1/2 and TET2 Genes in Acute Myeloid leukemia Patients
Manal Atef, Nevine Fawzy Shafik, Nagwa H.A. Hassan, Rasha Mahmoud Allam, Yomna Mohamed EL-Meligui, Hisham Abdelaziz
Asian Pac J Cancer Prev. 2023; 24(9): 3169–3182. doi: 10.31557/APJCP.2023.24.9.3169
PMCID:
PMC10762743
ArticlePDF–762K
6.
IDH1R132H mutation increases radiotherapy efficacy and a 4-gene radiotherapy-related signature of WHO grade 4 gliomas
Xuetao Han, Huandi Zhou, Wei Sun, Liubing Hou, Yanqiang Wang, Hong Wang, Zhongqiang Lv, Xiaoying Xue
Sci Rep. 2023; 13: 19659. Published online 2023 Nov 11. doi: 10.1038/s41598-023-46335-1
PMCID:
PMC10640646
ArticlePDF–5.3M
7.
IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma
Xueqin Chen, Jun Liu, Yuqin Li, Yuequan Zeng, Fang Wang, Zexiong Cheng, Hao Duan, Guopeng Pan, Shangqi Yang, Yuling Chen, Qing Li, Xi Shen, Ying Li, Zixi Qin, Jiahong Chen, Youwei Huang, Xiangyu Wang, Yuli Lu, Minfeng Shu, Yubo Zhang, Guocai Wang, Kai Li, Xi Lin, Fan Xing, Haipeng Zhang
Nat Commun. 2023; 14: 6781. Published online 2023 Oct 25. doi: 10.1038/s41467-023-42545-3
PMCID:
PMC10600173
ArticlePDF–11M
8.
Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation
Sinthu Pathmanapan, Raymond Poon, Tomasa Barrientos De Renshaw, Puviindran Nadesan, Makoto Nakagawa, Gireesh A. Seesankar, Adrian Kwan Ho Loe, Hongyuan H. Zhang, Joan J. Guinovart, Jordi Duran, Christopher B. Newgard, Jay S. Wunder, Benjamin A. Alman
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112578. Published online 2023 Jun 1. doi: 10.1016/j.celrep.2023.112578
PMCID:
PMC10592452
ArticlePDF–1.7M
9.
Diffusion tensor imaging‐based machine learning for IDH wild‐type glioblastoma stratification to reveal the biological underpinning of radiomic features
Zilong Wang, Fangzhan Guan, Wenchao Duan, Yu Guo, Dongling Pei, Yuning Qiu, Minkai Wang, Aoqi Xing, Zhongyi Liu, Bin Yu, Hongwei Zheng, Xianzhi Liu, Dongming Yan, Yuchen Ji, Jingliang Cheng, Jing Yan, Zhenyu Zhang
CNS Neurosci Ther. 2023 Nov; 29(11): 3339–3350. Published online 2023 May 24. doi: 10.1111/cns.14263
PMCID:
PMC10580329
ArticlePDF–29M
10.
Mutant IDH1 Cooperates with ATRX Loss to Drive the Alternative Lengthening of Telomere Phenotype in Glioma
Joydeep Mukherjee, Tor-Christian Johannessen, Shigeo Ohba, Tracy T. Chow, Lindsey Jones, Ajay Pandita, Russell O. Pieper
Cancer Res. Author manuscript; available in PMC 2023 Oct 16.
Published in final edited form as: Cancer Res. 2018 Jun 1; 78(11): 2966–2977. Published online 2018 Mar 15. doi: 10.1158/0008-5472.CAN-17-2269
PMCID:
PMC10578296
ArticlePDF–1.5M
11.
Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic–mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer
Kevin Gonthier, Cindy Weidmann, Line Berthiaume, Cynthia Jobin, Aurélie Lacouture, Camille Lafront, Mario Harvey, Bertrand Neveu, Jérémy Loehr, Alain Bergeron, Yves Fradet, Louis Lacombe, Julie Riopel, Éva Latulippe, Chantal Atallah, Michael Shum, Jean‐Philippe Lambert, Frédéric Pouliot, Martin Pelletier, Étienne Audet‐Walsh
Mol Oncol. 2023 Oct; 17(10): 2109–2125. Published online 2023 Jul 19. doi: 10.1002/1878-0261.13441
PMCID:
PMC10552900
ArticlePDF–1.0M
12.
Classification of IDH wild-type glioblastoma tumorspheres into low- and high-invasion groups based on their transcriptional program
Junseong Park, Jin-Kyoung Shim, Mirae Lee, Dokyeong Kim, Seon-Jin Yoon, Ju Hyung Moon, Eui Hyun Kim, Jeong-Yoon Park, Jong Hee Chang, Seok-Gu Kang
Br J Cancer. 2023 Oct 19; 129(7): 1061–1070. Published online 2023 Aug 9. doi: 10.1038/s41416-023-02391-y
PMCID:
PMC10539507
ArticlePDF–5.1M
13.
磁共振酰胺质子转移模态的胶质瘤IDH基因分型识别：基于深度学习的Dual-Aware框架
楚 智钦, 屈 耀铭, 钟 涛, 梁 淑君, 温 志波, 张 煜
Nan Fang Yi Ke Da Xue Xue Bao. 2023 Aug 20; 43(8): 1379–1387. Chinese. doi: 10.12122/j.issn.1673-4254.2023.08.15
PMCID:
PMC10505564
ArticlePDF–1.4M
14.
Diffuse Isocitrate Dehydrogenase–Mutant Gliomas With Histone H3 Alterations Are Distinguished by Unique Clinical Characteristics, Molecular Expression Profile, and Survival Prognosis
Cheng Cheng, Di Wang, Mingchen Yu, You Zhai, Changqing Pan, Bo Liang, Jiazheng Zhang, Chen Wang, Yiyun Yin, Lianwang Li, Fan Wu, Zhongfang Shi, Xing Fan, Xing Liu, Zhiliang Wang, Zheng Zhao, Guanzhang Li, Tao Jiang, Wei Zhang
Neurosurgery. 2023 Oct; 93(4): 802–812. Published online 2023 Apr 18. doi: 10.1227/neu.0000000000002495
PMCID:
PMC10476769
ArticlePDF–1001K
15.
The impact of IDH and NAT2 gene polymorphisms in acute myeloid leukemia risk and overall survival in an Arab population: A case-control study
Sohaib M. Al-Khatib, Obada Ababneh, Hassann Abushukair, Nour Abdo, Laith N. Al-Eitan
PLoS One. 2023; 18(7): e0289014. Published online 2023 Jul 21. doi: 10.1371/journal.pone.0289014
PMCID:
PMC10361469
ArticlePDF–988K
16.
Insulin‐like growth factor binding protein‐2 and glucose‐regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH‐wildtype glioblastoma patients
Abigail J. Harland, Claire M. Perks, Paul White, Kathreena M. Kurian, Hannah R. Barber
Cancer Med. 2023 Jul; 12(13): 14426–14439. Published online 2023 May 22. doi: 10.1002/cam4.6071
PMCID:
PMC10358216
ArticlePDF–6.9M
17.
Detection of IDH1 Mutation in cfDNA and Tissue of Adult Diffuse Glioma with Allele-Specific qPCR
Adil Husain, Sridhar Mishra, Mohammed Haris Siddiqui, Nuzhat Husain
Asian Pac J Cancer Prev. 2023; 24(3): 961–968. doi: 10.31557/APJCP.2023.24.3.961
PMCID:
PMC10334107
ArticlePDF–1.2M
18.
Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas
Markus Bredel, Lluís Espinosa, Hyunsoo Kim, Denise M. Scholtens, Joseph P. McElroy, Rajani Rajbhandari, Wei Meng, Thomas M. Kollmeyer, Tathiane M. Malta, Michael A. Quezada, Griffith R. Harsh, Teresa Lobo-Jarne, Laura Solé, Aran Merati, Surya Nagaraja, Sindhu Nair, Jaclyn J. White, Nanda K. Thudi, Jessica L. Fleming, Amy Webb, Atsushi Natsume, Seishi Ogawa, Ruthild G. Weber, Joan Bertran, S. Jaharul Haque, Bettina Hentschel, C. Ryan Miller, Frank B. Furnari, Timothy A. Chan, Anca-Ligia Grosu, Michael Weller, Jill S. Barnholtz-Sloan, Michelle Monje, Houtan Noushmehr, Robert B. Jenkins, C. Leland Rogers, David R. MacDonald, Stephanie L. Pugh, Arnab Chakravarti
Cell Rep Med. 2023 Jun 20; 4(6): 101082. Published online 2023 Jun 20. doi: 10.1016/j.xcrm.2023.101082
PMCID:
PMC10314122
ArticlePDF–6.5M
19.
Ovarian juvenile granulosa cell tumors with Ollier’s disease in children with IDH1 gene somatic mutation
Jin Zhang, Renwu Hua, Lishuang Ma, Chao Liu, Yanxia Zhang, Xuemin Lü, Tianren Wang, Naijun Wan
Front Endocrinol (Lausanne) 2023; 14: 1093273. Published online 2023 May 30. doi: 10.3389/fendo.2023.1093273
PMCID:
PMC10265673
ArticlePDF–1.3M
20.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
ArticlePDF–23M

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