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Items: 1 to 20 of 21

1.
KLHL29-mediated DDX3X degradation promotes chemosensitivity by abrogating cell cycle checkpoint in triple-negative breast cancer
Litong Yao, Qian Hao, Mozhi Wang, Yuhai Chen, Hongyi Cao, Qiang Zhang, Keda Yu, Yizhou Jiang, Zhiming Shao, Xiang Zhou, Yingying Xu
Oncogene. 2023; 42(47): 3514–3528. Published online 2023 Oct 16. doi: 10.1038/s41388-023-02858-5
PMCID:
PMC10656286
AbstractArticlePDF–8.8M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
4.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
5.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
6.
Genome-Wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions
Josyf C. Mychaleckyj, Alexandre Havt, Uma Nayak, Relana Pinkerton, Emily Farber, Patrick Concannon, Aldo A. Lima, Richard L. Guerrant
Mol Biol Evol. 2017 Mar; 34(3): 559–574. Published online 2017 Jan 18. doi: 10.1093/molbev/msw249
PMCID:
PMC5430616
AbstractArticlePDF–1.6M
7.
The novel fusion transcript NR5A2-KLHL29FT is generated by an insertion at the KLHL29 locus
Zhenguo Sun, Xiquan Ke, Steven L. Salzberg, Daehwan Kim, Valentin Antonescu, Yulan Cheng, Binbin Huang, Jee Hoon Song, John M. Abraham, Sariat Ibrahim, Hui Tian, Stephen J. Meltzer
Cancer. Author manuscript; available in PMC 2018 May 1.
Published in final edited form as: Cancer. 2017 May 1; 123(9): 1507–1515. Published online 2017 Jan 12. doi: 10.1002/cncr.30510
PMCID:
PMC5400694
AbstractArticlePDF–429K
8.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
Mikko Taipale, George Tucker, Jian Peng, Irina Krykbaeva, Zhen-Yuan Lin, Brett Larsen, Hyungwon Choi, Bonnie Berger, Anne-Claude Gingras, Susan Lindquist
Cell. Author manuscript; available in PMC 2015 Jul 17.
Published in final edited form as: Cell. 2014 Jul 17; 158(2): 434–448. doi: 10.1016/j.cell.2014.05.039
PMCID:
PMC4104544
AbstractArticlePDF–3.2M
9.
TRIM65 regulates microRNA activity by ubiquitination of TNRC6
Shitao Li, Lingyan Wang, Bishi Fu, Michael A. Berman, Alos Diallo, Martin E. Dorf
Proc Natl Acad Sci U S A. 2014 May 13; 111(19): 6970–6975. Published online 2014 Apr 28. doi: 10.1073/pnas.1322545111
PMCID:
PMC4024878
AbstractArticlePDF–1.1M
10.
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist
Cell. Author manuscript; available in PMC 2014 Jan 17.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047
PMCID:
PMC3894786
AbstractArticlePDF–5.0M
11.
Update on the Kelch-like (KLHL) gene family
Bajinder S Dhanoa, Tiziana Cogliati, Akhila G Satish, Elspeth A Bruford, James S Friedman
Hum Genomics. 2013; 7(1): 13. Published online 2013 May 15. doi: 10.1186/1479-7364-7-13
PMCID:
PMC3658946
AbstractArticlePDF–1.3M
12.
Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population
Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte
PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954
PMCID:
PMC3522587
AbstractArticlePDF–130K
13.
Genome-Wide Association Scan for Survival on Dialysis in African-Americans with Type 2 Diabetes
Mariana Murea, Lingyi Lu, Lijun Ma, Pamela J. Hicks, Jasmin Divers, Caitrin W. McDonough, Carl D. Langefeld, Donald W. Bowden, Barry I. Freedman
Am J Nephrol. 2011 Jun; 33(6): 502–509. Published online 2011 May 5. doi: 10.1159/000327985
PMCID:
PMC3202959
AbstractArticlePDF–425K
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project
Guillaume Lettre, Cameron D. Palmer, Taylor Young, Kenechi G. Ejebe, Hooman Allayee, Emelia J. Benjamin, Franklyn Bennett, Donald W. Bowden, Aravinda Chakravarti, Al Dreisbach, Deborah N. Farlow, Aaron R. Folsom, Myriam Fornage, Terrence Forrester, Ervin Fox, Christopher A. Haiman, Jaana Hartiala, Tamara B. Harris, Stanley L. Hazen, Susan R. Heckbert, Brian E. Henderson, Joel N. Hirschhorn, Brendan J. Keating, Stephen B. Kritchevsky, Emma Larkin, Mingyao Li, Megan E. Rudock, Colin A. McKenzie, James B. Meigs, Yang A. Meng, Tom H. Mosley, Jr., Anne B. Newman, Christopher H. Newton-Cheh, Dina N. Paltoo, George J. Papanicolaou, Nick Patterson, Wendy S. Post, Bruce M. Psaty, Atif N. Qasim, Liming Qu, Daniel J. Rader, Susan Redline, Muredach P. Reilly, Alexander P. Reiner, Stephen S. Rich, Jerome I. Rotter, Yongmei Liu, Peter Shrader, David S. Siscovick, W. H. Wilson Tang, Herman A. Taylor, Jr., Russell P. Tracy, Ramachandran S. Vasan, Kevin M. Waters, Rainford Wilks, James G. Wilson, Richard R. Fabsitz, Stacey B. Gabriel, Sekar Kathiresan, Eric Boerwinkle
PLoS Genet. 2011 Feb; 7(2): e1001300. Published online 2011 Feb 10. doi: 10.1371/journal.pgen.1001300
PMCID:
PMC3037413
AbstractArticlePDF–423K
16.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
17.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
18.
Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip
Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani
Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014
PMCID:
PMC2775832
AbstractArticlePDF–2.8M
19.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
20.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K

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