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Items: 1 to 20 of 27

1.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing
Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6
PMCID:
PMC8748958
AbstractArticlePDF–3.0M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9
PMCID:
PMC7910459
AbstractArticlePDF–3.3M
4.
Activin A-Mediated Regulation of XT-I in Human Skin Fibroblasts
Thanh-Diep Ly, Ricarda Plümers, Bastian Fischer, Vanessa Schmidt, Doris Hendig, Joachim Kuhn, Cornelius Knabbe, Isabel Faust
Biomolecules. 2020 Apr; 10(4): 609. Published online 2020 Apr 14. doi: 10.3390/biom10040609
PMCID:
PMC7226200
AbstractArticlePDF–2.3M
5.
Expression of xylosyltransferases I and II and their role in the pathogenesis of arthrofibrosis
Anke Bernstein, Sven N. A. Reichert, Norbert P. Südkamp, Sergio Latorre Hernandez, Andreas G. Nerlich, Jan Kühle, Hermann O. Mayr
J Orthop Surg Res. 2020; 15: 27. Published online 2020 Jan 23. doi: 10.1186/s13018-020-1544-8
PMCID:
PMC6979351
AbstractArticlePDF–1.2M
6.
GGC Repeat Expansion and Exon 1 Methylation of XYLT1 Is a Common Pathogenic Variant in Baratela-Scott Syndrome
Amy J. LaCroix, Deborah Stabley, Rebecca Sahraoui, Margaret P. Adam, Michele Mehaffey, Kelly Kernan, Candace T. Myers, Carrie Fagerstrom, George Anadiotis, Yassmine M. Akkari, Katherine M. Robbins, Karen W. Gripp, Wagner A.R. Baratela, Michael B. Bober, Angela L. Duker, Dan Doherty, Jennifer C. Dempsey, Daniel G. Miller, Martin Kircher, Michael J. Bamshad, Deborah A. Nickerson, University of Washington Center for Mendelian Genomics, Heather C. Mefford, Katia Sol-Church
Am J Hum Genet. 2019 Jan 3; 104(1): 35–44. Published online 2018 Dec 13. doi: 10.1016/j.ajhg.2018.11.005
PMCID:
PMC6323552
AbstractArticlePDF–1.0M
7.
microRNA-29b mediates fibrotic induction of human xylosyltransferase-I in human dermal fibroblasts via the Sp1 pathway
Lara Riedel, Bastian Fischer, Thanh-Diep Ly, Doris Hendig, Joachim Kuhn, Cornelius Knabbe, Isabel Faust
Sci Rep. 2018; 8: 17779. Published online 2018 Dec 12. doi: 10.1038/s41598-018-36217-2
PMCID:
PMC6290791
AbstractArticlePDF–1.4M
8.
Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1
David C. Briggs, Erhard Hohenester
Structure. 2018 Jun 5; 26(6): 801–809.e3. doi: 10.1016/j.str.2018.03.014
PMCID:
PMC5992326
AbstractArticlePDF–2.6M
9.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
12.
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin, Junjie Chen
Mol Syst Biol. 2015 Jan; 11(1): 775. Published online 2015 Jan 21. doi: 10.15252/msb.20145504
PMCID:
PMC4332150
AbstractArticlePDF–2.8M
13.
Xylosyltransferase-1 Expression Is Refractory to Inhibition by the Inflammatory Cytokines Tumor Necrosis Factor α and IL-1β in Nucleus Pulposus Cells: Novel Regulation by AP-1, Sp1, and Sp3
Wei Ye, Jie Zhou, Dessislava Z. Markova, Ye Tian, Jun Li, D. Greg Anderson, Irving M. Shapiro, Makarand V. Risbud
Am J Pathol. 2015 Feb; 185(2): 485–495. doi: 10.1016/j.ajpath.2014.09.021
PMCID:
PMC4305180
AbstractArticlePDF–1.2M
14.
First description of the complete human xylosyltransferase-I promoter region
Isabel Faust, Kai Oliver Böker, Christoph Lichtenberg, Joachim Kuhn, Cornelius Knabbe, Doris Hendig
BMC Genet. 2014; 15: 129. Published online 2014 Dec 5. doi: 10.1186/s12863-014-0129-0
PMCID:
PMC4264549
AbstractArticlePDF–1.2M
15.
XYLT1 Mutations in Desbuquois Dysplasia Type 2
Catherine Bui, Céline Huber, Beyhan Tuysuz, Yasemin Alanay, Christine Bole-Feysot, Jules G. Leroy, Geert Mortier, Patrick Nitschke, Arnold Munnich, Valérie Cormier-Daire
Am J Hum Genet. 2014 Mar 6; 94(3): 405–414. doi: 10.1016/j.ajhg.2014.01.020
PMCID:
PMC3951945
AbstractArticlePDF–939K
16.
CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression
Dong Young Kim, Eunju Kwon, Paul D. Hartley, David C. Crosby, Sumanjit Mann, Nevan J. Krogan, John D. Gross
Mol Cell. Author manuscript; available in PMC 2014 Feb 21.
Published in final edited form as: Mol Cell. 2013 Feb 21; 49(4): 632–644. Published online 2013 Jan 17. doi: 10.1016/j.molcel.2012.12.012
PMCID:
PMC3582769
AbstractArticlePDF–4.5M
17.
Identification of a Candidate Gene for Astigmatism
Margarida C. Lopes, Pirro G. Hysi, Virginie J. M. Verhoeven, Stuart Macgregor, Alex W. Hewitt, Grant W. Montgomery, Phillippa Cumberland, Johannes R. Vingerling, Terri L. Young, Cornelia M. van Duijn, Ben Oostra, Andre G. Uitterlinden, Jugnoo S. Rahi, David A. Mackey, Caroline C. W. Klaver, Toby Andrew, Christopher J. Hammond
Invest Ophthalmol Vis Sci. 2013 Feb; 54(2): 1260–1267. Published online 2013 Feb 13. doi: 10.1167/iovs.12-10463
PMCID:
PMC3576051
AbstractArticlePDF–282K
18.
Regulation of Xylosyltransferase I Gene Expression by Interleukin 1β in Human Primary Chondrocyte Cells: MECHANISM AND IMPACT ON PROTEOGLYCAN SYNTHESIS
Mostafa Khair, Mustapha Bourhim, Lydia Barré, Dong Li, Patrick Netter, Jacques Magdalou, Sylvie Fournel-Gigleux, Mohamed Ouzzine
J Biol Chem. 2013 Jan 18; 288(3): 1774–1784. Published online 2012 Dec 5. doi: 10.1074/jbc.M112.419887
PMCID:
PMC3548487
AbstractArticlePDF–1.6M
19.
Xylosyltransferase-I Regulates Glycosaminoglycan Synthesis during the Pathogenic Process of Human Osteoarthritis
Narayanan Venkatesan, Lydia Barré, Mustapha Bourhim, Jacques Magdalou, Didier Mainard, Patrick Netter, Sylvie Fournel-Gigleux, Mohamed Ouzzine
PLoS One. 2012; 7(3): e34020. Published online 2012 Mar 30. doi: 10.1371/journal.pone.0034020
PMCID:
PMC3316535
AbstractArticlePDF–1019K
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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