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Items: 1 to 20 of 400

1.
β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53
Mohamed Bourmoum, Nikolina Radulovich, Amit Sharma, Johnny M. Tkach, Ming-Sound Tsao, Laurence Pelletier
PLoS One. 2024; 19(2): e0295030. Published online 2024 Feb 7. doi: 10.1371/journal.pone.0295030
PMCID:
PMC10849215
AbstractArticlePDF–2.1M
2.
APC mutations disrupt β-catenin destruction complex condensates organized by Axin phase separation
Dan Zhang, Qi-Qi Ni, Shu-Yang Wang, Wen-Feng He, Ze-Xuan Hong, Hui-Ye Liu, Xiao-Hong Chen, Li-Jie Chen, Fang-Yi Han, Ling-Jie Zhang, Xiao-ming Li, Yan-qing Ding, Hong-li Jiao, Ya-ping Ye
Cell Mol Life Sci. 2024 Dec; 81(1): 57. Published online 2024 Jan 27. doi: 10.1007/s00018-023-05068-0
PMCID:
PMC10817841
AbstractArticlePDF–6.2M
3.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
4.
APC ameliorates idiopathic membranous nephropathy by affecting podocyte apoptosis through the ERK1/2/YB-1/PLA2R1 axis
Ben Ke, Wen Shen, Yunfei Liao, Jing Hu, Weiping Tu, Xiangdong Fang
Mol Cell Biochem. 2023; 478(9): 1999–2011. Published online 2023 Jan 2. doi: 10.1007/s11010-022-04650-7
PMCID:
PMC10359206
AbstractArticlePDF–7.9M
5.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
6.
Let‐7b‐5p inhibits colon cancer progression by prohibiting APC ubiquitination degradation and the Wnt pathway by targeting NKD1
Yuyang Dai, Jinsong Liu, Xuyan Li, Jianzhong Deng, Cheng Zeng, Wenbin Lu, Yongzhong Hou, Ying Sheng, Honglin Wu, Qian Liu
Cancer Sci. 2023 May; 114(5): 1882–1897. Published online 2022 Dec 9. doi: 10.1111/cas.15678
Correction in:
Cancer Sci. 2023 Aug; 114(8): 3466–3469.
PMCID:
PMC10154867
AbstractArticlePDF–30M
7.
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders
Greta Pintacuda, Yu-Han H. Hsu, Kalliopi Tsafou, Ka Wan Li, Jacqueline M. Martín, Jackson Riseman, Julia C. Biagini, Joshua K.T. Ching, Daya Mena, Miguel A. Gonzalez-Lozano, Shawn B. Egri, Jake Jaffe, August B. Smit, Nadine Fornelos, Kevin C. Eggan, Kasper Lage
Cell Genom. 2023 Mar 8; 3(3): 100250. Published online 2023 Jan 24. doi: 10.1016/j.xgen.2022.100250
PMCID:
PMC10025425
AbstractArticlePDF–22M
8.
Rare Genetic Variants in Human APC Are Implicated in Mesiodens and Isolated Supernumerary Teeth
Chomchanok Panyarat, Siriruk Nakornchai, Kanoknart Chintakanon, Niramol Leelaadisorn, Worrachet Intachai, Bjorn Olsen, Sissades Tongsima, Ploy Adisornkanj, Chumpol Ngamphiw, Timothy C. Cox, Piranit Kantaputra
Int J Mol Sci. 2023 Mar; 24(5): 4255. Published online 2023 Feb 21. doi: 10.3390/ijms24054255
PMCID:
PMC10002335
AbstractArticlePDF–3.3M
9.
Interactomes of Glycogen Synthase Kinase-3 Isoforms
Kevin W. Cormier, Brett Larsen, Anne-Claude Gingras, James R. Woodgett
J Proteome Res. 2023 Mar 3; 22(3): 977–989. Published online 2023 Feb 13. doi: 10.1021/acs.jproteome.2c00825
PMCID:
PMC9990120
AbstractArticlePDF–3.7M
10.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
11.
The Mutation Spectrum and Two Novel Point Mutations in the APC Gene in Vietnamese Patients with Familial Adenomatous Polyposis
Bac Hoang Nguyen, Suong Thi Bang Nguyen, Huy Huu Nguyen, Tin Trung Nguyen, Khoi Minh Le
Asian Pac J Cancer Prev. 2022 May; 23(5): 1517–1522. doi: 10.31557/APJCP.2022.23.5.1517
PMCID:
PMC9587892
AbstractArticlePDF–1.3M
12.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
AbstractArticlePDF–2.1M
13.
Constitutional chromothripsis of the APC locus as a cause of genetic predisposition to colon cancer
Florentine Scharf, Rafaela Magalhaes Leal Silva, Monika Morak, Alex Hastie, Julia M A Pickl, Kai Sendelbach, Christian Gebhard, Melanie Locher, Andreas Laner, Verena Steinke-Lange, Udo Koehler, Elke Holinski-Feder, Dieter A Wolf
J Med Genet. 2022 Oct; 59(10): 976–983. Published online 2021 Dec 14. doi: 10.1136/jmedgenet-2021-108147
PMCID:
PMC9554066
AbstractArticlePDF–1.7M
14.
CDH1、FANCB和APC基因多态性与中国人群肺癌易感性的关系
苏 联椿, 黄 华, 高 敏, 李 永文, 施 睿峰, 陈 琛, 李 宣广, 朱 光胜, 刘 红雨, 陈 军
Zhongguo Fei Ai Za Zhi. 2022 Sep 20; 25(9): 658–664. Chinese. doi: 10.3779/j.issn.1009-3419.2022.102.21
PMCID:
PMC9549421
AbstractArticlePDF–1.9M
15.
Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1
Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John A. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja N. Kettenbach, David A. Guertin
J Biol Chem. 2022 Oct; 298(10): 102379. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102379
PMCID:
PMC9513271
AbstractArticlePDF–2.7M
16.
Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB
Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan
EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698
PMCID:
PMC9433938
AbstractArticlePDF–9.3M
17.
Adenomatous polyposis coli (APC) in cell migration
Xingyuan Fang, Tatyana M. Svitkina
Eur J Cell Biol. Author manuscript; available in PMC 2023 Jun 1.
Published in final edited form as: Eur J Cell Biol. 2022 Jun-Aug; 101(3): 151228. Published online 2022 Apr 22. doi: 10.1016/j.ejcb.2022.151228
PMCID:
PMC9357102
AbstractArticlePDF–1.1M
18.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
19.
Comprehensive functional genomic analyses link APC somatic mutation and mRNA-miRNA networks to the clinical outcome of stage-III colorectal cancer patients
Sum-Fu Chiang, Heng-Hsuan Huang, Wen-Sy Tsai, Bertrand Chin-Ming Tan, Chia-Yu Yang, Po-Jung Huang, Ian Yi-Feng Chang, Jiarong Lin, Pei-Shan Lu, En Chin, Yu-Hao Liu, Jau-Song Yu, Jy-Ming Chiang, Hsin-Yuan Hung, Jeng-Fu You, Hsuan Liu
Biomed J. 2022 Apr; 45(2): 347–360. Published online 2021 Mar 16. doi: 10.1016/j.bj.2021.03.001
PMCID:
PMC9250073
AbstractArticlePDF–3.1M
20.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M

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