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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 96709662.

Identification of PAX6 and NFAT4 as the Transcriptional Regulators of the Long Noncoding RNA Mrhl in Neuronal Progenitors

Debosree Pal, Sangeeta Dutta, Dhanur P. Iyer, Deepika Shriram, Utsa Bhaduri, M. R. S. Rao

Mol Cell Biol. 2022 Nov; 42(11): e00036-22. Published online 2022 Nov 1. doi: 10.1128/mcb.00036-22

PMCID:: PMC9670966

Abstract Article PDF–3.8M

Select item 82632853.

NFAT transcription factors are essential and redundant actors for leukemia initiating potential in T-cell acute lymphoblastic leukemia

Claire Catherinet, Diana Passaro, Stéphanie Gachet, Hind Medyouf, Anne Reynaud, Charlène Lasgi, Jacques Ghysdael, Christine Tran Quang

PLoS One. 2021; 16(7): e0254184. Published online 2021 Jul 7. doi: 10.1371/journal.pone.0254184

PMCID:: PMC8263285

Abstract Article PDF–2.4M

Select item 77926824.

NFATc3 regulation of collagen V expression contributes to cellular immunity to collagen type V and hypoxic pulmonary hypertension

Joshua R. Sheak, David T. Jones, Benjamin J. Lantz, Levi D. Maston, Danielle Vigil, Thomas C. Resta, Micaela M. Resta, Tamara A. Howard, Nancy L. Kanagy, Yan Guo, Ewa Jankowska-Gan, Jeremy A. Sullivan, Rudolf K. Braun, William J. Burlingham, Laura V. Gonzalez Bosc

Am J Physiol Lung Cell Mol Physiol. 2020 Dec 1; 319(6): L968–L980. Published online 2020 Sep 30. doi: 10.1152/ajplung.00184.2020

PMCID:: PMC7792682

Abstract Article

Select item 71243075.

A new comprehensive method for detection of livestock-related pathogenic viruses using a target enrichment system

Mami Oba, Shinobu Tsuchiaka, Tsutomu Omatsu, Yukie Katayama, Konosuke Otomaru, Teppei Hirata, Hiroshi Aoki, Yoshiteru Murata, Shinji Makino, Makoto Nagai, Tetsuya Mizutani

Biochem Biophys Res Commun. 2018 Jan 8; 495(2): 1871–1877. Published online 2017 Dec 6. doi: 10.1016/j.bbrc.2017.12.017

PMCID:: PMC7124307

Abstract Article PDF–1.3M

Select item 69299946.

NFATc3-dependent expression of miR-153-3p promotes mitochondrial fragmentation in cardiac hypertrophy by impairing mitofusin-1 expression

Tao Wang, Mei Zhai, Sheng Xu, Murugavel Ponnusamy, Yan Huang, Cui-Yun Liu, Man Wang, Chan Shan, Pei-Pei Shan, Xiang-Qian Gao, Kai Wang, Xin-Zhe Chen, Jing Liu, Jing-Yi Xie, De-Yu Zhang, Lu-yu Zhou, Kun Wang

Theranostics. 2020; 10(2): 553–566. Published online 2020 Jan 1. doi: 10.7150/thno.37181

PMCID:: PMC6929994

Abstract Article PDF–1.8M

Select item 67281817.

Non-Canonical Wnt-Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons

Melissa G. McKenzie, Lucy V. Cobbs, Patrick D. Dummer, Timothy J. Petros, Michael M. Halford, Steven Stacker, Yimin Zou, Gord J. Fishell, Edmund Au

Neuron. Author manuscript; available in PMC 2020 Sep 4.

Published in final edited form as: Neuron. 2019 Sep 4; 103(5): 853–864.e4. Published online 2019 Jun 27. doi: 10.1016/j.neuron.2019.06.003

PMCID:: PMC6728181

Abstract Article PDF–1.1M

Select item 66586618.

Orai1 inhibitor STIM2β regulates myogenesis by controlling SOCE dependent transcriptional factors

Kyu Min Kim, Anshul Rana, Chan Young Park

Sci Rep. 2019; 9: 10794. Published online 2019 Jul 25. doi: 10.1038/s41598-019-47259-5

PMCID:: PMC6658661

Abstract Article PDF–7.9M

Select item 62759199.

The mitochondrial localization of RelB and NFATx in immature T cells

Izabela Stasik, Andrzej Rapak, Ewa Zioło, Leon Strządała

Cell Mol Biol Lett. 2008 Dec; 13(4): 493–501. Published online 2008 May 6. doi: 10.2478/s11658-008-0019-4

PMCID:: PMC6275919

Summary PDF–461K

Select item 582818210.

Inhibition of nuclear factor of activated T cells (NFAT) c3 activation attenuates acute lung injury and pulmonary edema in murine models of sepsis

Manjula Karpurapu, Yong Gyu Lee, Ziqing Qian, Jin Wen, Megan N. Ballinger, Luiza Rusu, Sangwoon Chung, Jing Deng, Feng Qian, Brenda F. Reader, Teja Srinivas Nirujogi, Gye Young Park, Dehua Pei, John W. Christman

Oncotarget. 2018 Feb 13; 9(12): 10606–10620. Published online 2018 Jan 25. doi: 10.18632/oncotarget.24320

PMCID:: PMC5828182

Abstract Article PDF–4.9M

Select item 567552211.

Frizzled-5: A High Affinity Receptor for Secreted Frizzled-Related Protein-2 Activation of Nuclear Factor of Activated T-Cells c3 Signaling to Promote Angiogenesis

Yuri K. Peterson, Patrick Nasarre, Ingrid V. Bonilla, Eleanor Hilliard, Jennifer Samples, Thomas A. Morinelli, Elizabeth G. Hill, Nancy Klauber-DeMore

Angiogenesis. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Angiogenesis. 2017 Nov; 20(4): 615–628. Published online 2017 Aug 24. doi: 10.1007/s10456-017-9574-5

PMCID:: PMC5675522

Abstract Article PDF–742K

Select item 564508212.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 559266813.

Heterodimers of the transcriptional factors NFATc3 and FosB mediate tissue factor expression for 15(S)-hydroxyeicosatetraenoic acid–induced monocyte trafficking

Sivareddy Kotla, Nikhlesh K. Singh, Daniel Kirchhofer, Gadiparthi N. Rao

J Biol Chem. 2017 Sep 8; 292(36): 14885–14901. Published online 2017 Jul 19. doi: 10.1074/jbc.M117.804344

Correction in:: J Biol Chem. 2022 Apr; 298(4): 101812.

PMCID:: PMC5592668

Abstract Article PDF–1.5M

Select item 557792014.

Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions

Amy E Brinegar, Zheng Xia, James Anthony Loehr, Wei Li, George Gerald Rodney, Thomas A Cooper

eLife. 2017; 6: e27192. Published online 2017 Aug 11. doi: 10.7554/eLife.27192

PMCID:: PMC5577920

Abstract Article PDF–3.6M

Select item 557045715.

Epithelial calcineurin controls microbiota-dependent intestinal tumor development

Kenneth Peuker, Stefanie Muff, Jun Wang, Sven Künzel, Esther Bosse, Yvonne Zeissig, Giuseppina Luzzi, Marijana Basic, Anne Strigli, Andrea Ulbricht, Arthur Kaser, Alexander Arlt, Triantafyllos Chavakis, Gijs R van den Brink, Clemens Schafmayer, Jan-Hendrik Egberts, Thomas Becker, Marco E Bianchi, André Bleich, Christoph Röcken, Jochen Hampe, Stefan Schreiber, John F Baines, Richard S Blumberg, Sebastian Zeissig

Nat Med. Author manuscript; available in PMC 2017 Aug 24.

Published in final edited form as: Nat Med. 2016 May; 22(5): 506–515. Published online 2016 Apr 4. doi: 10.1038/nm.4072

PMCID:: PMC5570457

Abstract Article PDF–1.1M

Select item 529582116.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 527032517.

NFATc3 and VIP in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease

Anthony M. Szema, Edward Forsyth, Benjamin Ying, Sayyed A. Hamidi, John J. Chen, Sonya Hwang, Jonathan C. Li, Debra Sabatini Dwyer, Juan M. Ramiro-Diaz, Wieslawa Giermakowska, Laura V. Gonzalez Bosc

PLoS One. 2017; 12(1): e0170606. Published online 2017 Jan 26. doi: 10.1371/journal.pone.0170606

PMCID:: PMC5270325

Abstract Article PDF–2.2M

Select item 509692318.

Store-operated Ca²⁺ entry regulates Ca²⁺-activated chloride channels and eccrine sweat gland function

Axel R. Concepcion, Martin Vaeth, Larry E. Wagner, II, Miriam Eckstein, Lee Hecht, Jun Yang, David Crottes, Maximilian Seidl, Hyosup P. Shin, Carl Weidinger, Scott Cameron, Stuart E. Turvey, Thomas Issekutz, Isabelle Meyts, Rodrigo S. Lacruz, Mario Cuk, David I. Yule, Stefan Feske

J Clin Invest. 2016 Nov 1; 126(11): 4303–4318. Published online 2016 Oct 10. doi: 10.1172/JCI89056

PMCID:: PMC5096923

Abstract Article PDF–5.0M

Select item 506823719.

NFATC3 promotes IRF7 transcriptional activity in plasmacytoid dendritic cells

Musheng Bao, York Wang, Ying Liu, Peiqing Shi, Hongbo Lu, Wenwen Sha, Leiyun Weng, Shino Hanabuchi, Jun Qin, Joel Plumas, Laurence Chaperot, Zhiqiang Zhang, Yong-Jun Liu

J Exp Med. 2016 Oct 17; 213(11): 2383–2398. doi: 10.1084/jem.20160438

PMCID:: PMC5068237

Abstract Article PDF–3.0M

Select item 496719420.

ASIC1-mediated calcium entry stimulates NFATc3 nuclear translocation via PICK1 coupling in pulmonary arterial smooth muscle cells

Laura V. Gonzalez Bosc, Danielle R. Plomaritas, Lindsay M. Herbert, Wieslawa Giermakowska, Carly Browning, Nikki L. Jernigan

Am J Physiol Lung Cell Mol Physiol. 2016 Jul 1; 311(1): L48–L58. Published online 2016 May 17. doi: 10.1152/ajplung.00040.2016

PMCID:: PMC4967194

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