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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 101329742.

Age-associated microenvironmental changes highlight the role of PDGF-C in ER⁺ breast cancer metastatic relapse

Frances K. Turrell, Rebecca Orha, Naomi J. Guppy, Andrea Gillespie, Matthew Guelbert, Chris Starling, Syed Haider, Clare M. Isacke

Nat Cancer. 2023; 4(4): 468–484. Published online 2023 Mar 13. doi: 10.1038/s43018-023-00525-y

PMCID:: PMC10132974

Abstract Article PDF–28M

Select item 93821163.

Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development

Sara Gillnäs, Radiosa Gallini, Liqun He, Christer Betsholtz, Johanna Andrae

Biol Open. 2022 Aug 15; 11(8): bio059431. Published online 2022 Aug 9. doi: 10.1242/bio.059431

PMCID:: PMC9382116

Abstract Article PDF–13M

Select item 86337834.

Expression and function of PDGF-C in development and stem cells

Yi Tian, Ying Zhan, Qin Jiang, Weisi Lu, Xuri Li

Open Biol. 2021 Dec; 11(12): 210268. Published online December 1, 2021. doi: 10.1098/rsob.210268

PMCID:: PMC8633783

Abstract Article PDF–982K

Select item 83138635.

Srsf3 mediates alternative RNA splicing downstream of PDGFRα signaling in the facial mesenchyme

Brenna J. C. Dennison, Eric D. Larson, Rui Fu, Julia Mo, Katherine A. Fantauzzo

Development. 2021 Jul 15; 148(14): dev199448. Published online 2021 Jul 13. doi: 10.1242/dev.199448

PMCID:: PMC8313863

Abstract Article

Select item 77595796.

Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood–brain barrier

Manuel Zeitelhofer, Milena Z. Adzemovic, Christine Moessinger, Christina Stefanitsch, Carina Strell, Lars Muhl, Lou Brundin, Linda Fredriksson, Tomas Olsson, Ulf Eriksson, Ingrid Nilsson

Sci Rep. 2020; 10: 22383. Published online 2020 Dec 24. doi: 10.1038/s41598-020-79598-z

PMCID:: PMC7759579

Abstract Article PDF–7.7M

Select item 74837477.

Transcriptional analysis of cleft palate in TGFβ3 mutant mice

J. Liu, S. K. Chanumolu, K. M. White, M. Albahrani, H. H. Otu, A. Nawshad

Sci Rep. 2020; 10: 14940. Published online 2020 Sep 10. doi: 10.1038/s41598-020-71636-0

PMCID:: PMC7483747

Abstract Article PDF–4.1M

Select item 68481888.

RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2

Barbara Nicol, Sara A. Grimm, Frédéric Chalmel, Estelle Lecluze, Maëlle Pannetier, Eric Pailhoux, Elodie Dupin-De-Beyssat, Yann Guiguen, Blanche Capel, Humphrey H.-C. Yao

Nat Commun. 2019; 10: 5116. Published online 2019 Nov 11. doi: 10.1038/s41467-019-13060-1

PMCID:: PMC6848188

Abstract Article PDF–13M

Select item 66292409.

Tie2 regulates endocardial sprouting and myocardial trabeculation

Xianghu Qu, Cristina Harmelink, H. Scott Baldwin

JCI Insight. 2019 Jul 11; 4(13): e96002. Published online 2019 Jul 11. doi: 10.1172/jci.insight.96002

PMCID:: PMC6629240

Abstract Article PDF–60M

Select item 613650710.

Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development

P. J. E. Uijtdewilligen, E. M. Versteeg, E. M. A. van de Westerlo, J. van der Vlag, W. F. Daamen, T. H. van Kuppevelt

Biomed Res Int. 2018; 2018: 9873471. Published online 2018 Aug 29. doi: 10.1155/2018/9873471

PMCID:: PMC6136507

Abstract Article PDF–838K

Select item 605163511.

Preclinical toxicological assessment of a novel monoclonal antibody targeting human platelet-derived growth factor CC (PDGF-CC) in PDGF-CC^hum mice

Manuel Zeitelhofer, Hong Li, Milena Z. Adzemovic, Ingrid Nilsson, Lars Muhl, Andrew M. Scott, Ulf Eriksson

PLoS One. 2018; 13(7): e0200649. Published online 2018 Jul 18. doi: 10.1371/journal.pone.0200649

PMCID:: PMC6051635

Abstract Article PDF–11M

Select item 596589912.

Metabolic benefits of inhibition of p38α in white adipose tissue in obesity

Shengjie Zhang, Hongchao Cao, Yan Li, Yanyan Jing, Shengnan Liu, Cheng Ye, Hui Wang, Shuxian Yu, Chengyuan Peng, Lijian Hui, Yu-cheng Wang, Haibing Zhang, Feifan Guo, Qiwei Zhai, Hui Wang, Ruimin Huang, Ling Zhang, Jingjing Jiang, Wei Liu, Hao Ying

PLoS Biol. 2018 May; 16(5): e2004225. Published online 2018 May 11. doi: 10.1371/journal.pbio.2004225

PMCID:: PMC5965899

Abstract Article PDF–13M

Select item 589672913.

Microenvironmental control of breast cancer subtype elicited by paracrine platelet derived growth factor-CC signaling

Pernilla Roswall, Matteo Bocci, Michael Bartoschek, Hong Li, Glen Kristiansen, Sara Jansson, Sophie Lehn, Jonas Sjölund, Steven Reid, Christer Larsson, Pontus Eriksson, Charlotte Anderberg, Eliane Cortez, Lao H Saal, Christina Orsmark-Pietras, Eugenia Cordero, B Kristian Haller, Jari Häkkinen, Ingrid JG Burvenich, Elgene Lim, Akira Orimo, Mattias Höglund, Lisa Rydén, Holger Moch, Andrew M Scott, Ulf Eriksson, Kristian Pietras

Nat Med. Author manuscript; available in PMC 2018 Sep 12.

Published in final edited form as: Nat Med. 2018 May; 24(4): 463–473. Published online 2018 Mar 12. doi: 10.1038/nm.4494

PMCID:: PMC5896729

Abstract Article PDF–2.7M

Select item 586818114.

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice

Jin Li, Su-Ping Deng, Gang Wei, Peng Yu

Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012

PMCID:: PMC5868181

Abstract Article PDF–653K

Select item 570207315.

Dysregulated PDGFRα signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification

Fenglei He, Philippe Soriano

Development. 2017 Nov 1; 144(21): 4026–4036. doi: 10.1242/dev.151068

PMCID:: PMC5702073

Abstract Article

Select item 558762816.

Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke

Enming Joseph Su, Chunzhang Cao, Linda Fredriksson, Ingrid Nilsson, Christina Stefanitsch, Tamara K. Stevenson, Juanjuan Zhao, Margret Ragsdale, Yu-Yo Sun, Manuel Yepes, Chia-Yi Kuan, Ulf Eriksson, Dudley K. Strickland, Daniel A. Lawrence, Li Zhang

Acta Neuropathol. 2017; 134(4): 585–604. Published online 2017 Jul 19. doi: 10.1007/s00401-017-1749-z

PMCID:: PMC5587628

Abstract Article PDF–7.3M

Select item 498044817.

Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat

Takahiro Seki, Kayoko Hosaka, Sharon Lim, Carina Fischer, Jennifer Honek, Yunlong Yang, Patrik Andersson, Masaki Nakamura, Erik Näslund, Seppo Ylä-Herttuala, Meili Sun, Hideki Iwamoto, Xuri Li, Yizhi Liu, Nilesh J. Samani, Yihai Cao

Nat Commun. 2016; 7: 12152. Published online 2016 Aug 5. doi: 10.1038/ncomms12152

PMCID:: PMC4980448

Abstract Article PDF–4.0M

Select item 489067518.

A role for PDGF-C/PDGFRα signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex

Johanna Andrae, Leonor Gouveia, Radiosa Gallini, Liqun He, Linda Fredriksson, Ingrid Nilsson, Bengt R. Johansson, Ulf Eriksson, Christer Betsholtz

Biol Open. 2016 Apr 15; 5(4): 461–474. Published online 2016 Mar 17. doi: 10.1242/bio.017368

PMCID:: PMC4890675

Abstract Article PDF–3.3M

Select item 481488719.

High glucose induces platelet‐derived growth factor‐C via carbohydrate response element‐binding protein in glomerular mesangial cells

Hiroya Kitsunai, Yuichi Makino, Hidemitsu Sakagami, Katsutoshi Mizumoto, Tsuyoshi Yanagimachi, Kuralay Atageldiyeva, Yasutaka Takeda, Yukihiro Fujita, Atsuko Abiko, Yumi Takiyama, Masakazu Haneda

Physiol Rep. 2016 Mar; 4(6): e12730. Published online 2016 Mar 31. doi: 10.14814/phy2.12730

PMCID:: PMC4814887

Abstract Article PDF–2.3M

Select item 431955920.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

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