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Items: 1 to 20 of 348

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Activation-induced deaminase expression defines mature B cell lymphoma in the mouse
Carmen Gómez-Escolar, Ester Marina-Zárate, Almudena R. Ramiro
Front Immunol. 2023; 14: 1268930. Published online 2023 Sep 21. doi: 10.3389/fimmu.2023.1268930
PMCID:
PMC10558245
AbstractArticlePDF–2.2M
3.
Selective Recognition of Carbohydrate Antigens by Germline Antibodies Isolated from AID Knockout Mice
Andrew T. DeLaitsch, Jacey R. Pridgen, Avery Tytla, Megan L. Peach, Rayleen Hu, David W. Farnsworth, Aislinn K. McMillan, Natalie Flanagan, J. Sebastian Temme, Marc C. Nicklaus, Jeffrey C. Gildersleeve
J Am Chem Soc. Author manuscript; available in PMC 2023 Sep 18.
Published in final edited form as: J Am Chem Soc. 2022 Mar 23; 144(11): 4925–4941. Published online 2022 Mar 12. doi: 10.1021/jacs.1c12745
PMCID:
PMC10506689
AbstractArticlePDF–2.3M
4.
An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut resident plasma cells
Simona Ceglia, Alyssa Berthelette, Kelsey Howley, Yun Li, Benedikt Mortzfeld, Shakti K. Bhattarai, Nicole K. H. Yiew, Ying Xu, Robert Brink, Jason G. Cyster, Lora V. Hooper, Gwendalyn J. Randolph, Vanni Bucci, Andrea Reboldi
Nat Immunol. Author manuscript; available in PMC 2023 Jun 6.
Published in final edited form as: Nat Immunol. 2023 Mar; 24(3): 531–544. Published online 2023 Jan 19. doi: 10.1038/s41590-022-01413-w
PMCID:
PMC10243503
AbstractArticlePDF–7.1M
5.
Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis
Yavuz F. Yazicioglu, Eros Marin, Ciaran Sandhu, Silvia Galiani, Iwan G. A. Raza, Mohammad Ali, Barbara Kronsteiner, Ewoud B. Compeer, Moustafa Attar, Susanna J. Dunachie, Michael L. Dustin, Alexander J. Clarke
Nat Immunol. 2023; 24(6): 991–1006. Published online 2023 Apr 24. doi: 10.1038/s41590-023-01484-3
PMCID:
PMC10232359
AbstractArticlePDF–7.6M
6.
B cell-specific knockout of AID protects against atherosclerosis
Talin Ebrahimian, France Dierick, Vincent Ta, Maria Kotsiopriftis, Jonathan O’Connor Miranda, Koren K. Mann, Alexandre Orthwein, Stephanie Lehoux
Sci Rep. 2023; 13: 8723. Published online 2023 May 30. doi: 10.1038/s41598-023-35980-1
PMCID:
PMC10229602
AbstractArticlePDF–1.4M
7.
Intrinsic B cell TLR-BCR linked coengagement induces class-switched, hypermutated, neutralizing antibody responses in absence of T cells
Carlos E. Rivera, Yulai Zhou, Daniel P. Chupp, Hui Yan, Amanda D. Fisher, Raphael Simon, Hong Zan, Zhenming Xu, Paolo Casali
Sci Adv. 2023 Apr; 9(17): eade8928. Published online 2023 Apr 28. doi: 10.1126/sciadv.ade8928
PMCID:
PMC10146914
AbstractArticlePDF–4.1M
8.
Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the efficacy of immune responses
Siân E. Jossi, Melissa Arcuri, Areej Alshayea, Ruby R. Persaud, Edith Marcial-Juárez, Elena Palmieri, Roberta Di Benedetto, Marisol Pérez-Toledo, Jamie Pillaye, Will M. Channell, Anna E. Schager, Rachel E. Lamerton, Charlotte N. Cook, Margaret Goodall, Takeshi Haneda, Andreas J. Bäumler, Lucy H. Jackson-Jones, Kai-Michael Toellner, Calman A. MacLennan, Ian R. Henderson, Francesca Micoli, Adam F. Cunningham
Front Immunol. 2023; 14: 1139329. Published online 2023 Mar 23. doi: 10.3389/fimmu.2023.1139329
PMCID:
PMC10076549
AbstractArticlePDF–4.2M
9.
Universal recording of cell–cell contacts in vivo for interaction-based transcriptomics
Sandra Nakandakari-Higa, Maria C. C. Canesso, Sarah Walker, Aleksey Chudnovskiy, Johanne T. Jacobsen, Jana Bilanovic, S. Martina Parigi, Karol Fiedorczuk, Elaine Fuchs, Angelina M. Bilate, Giulia Pasqual, Daniel Mucida, Yuri Pritykin, Gabriel D. Victora
Version 2. bioRxiv. Preprint. 2023 Mar 20 [revised 2023 Apr 18]. doi: 10.1101/2023.03.16.533003
PMCID:
PMC10055214
AbstractArticlePDF–7.2M
10.
Activation-induced cytidine deaminase expression by thymic B cells promotes T-cell tolerance and limits autoimmunity
Félix Lombard-Vadnais, Geneviève Chabot-Roy, Astrid Zahn, Sahily Rodriguez Torres, Javier M. Di Noia, Heather J. Melichar, Sylvie Lesage
iScience. 2023 Jan 20; 26(1): 105852. Published online 2022 Dec 21. doi: 10.1016/j.isci.2022.105852
PMCID:
PMC9840937
AbstractArticlePDF–4.1M
11.
Senataxin and RNase H2 act redundantly to suppress genome instability during class switch recombination
Hongchang Zhao, Stella R Hartono, Kirtney Mae Flores de Vera, Zheyuan Yu, Krishni Satchi, Tracy Zhao, Roger Sciammas, Lionel Sanz, Frédéric Chédin, Jacqueline Barlow
eLife. 2022; 11: e78917. Published online 2022 Dec 21. doi: 10.7554/eLife.78917
PMCID:
PMC9771370
AbstractArticlePDF–3.4M
12.
Single cell clonal analysis identifies an AID‐dependent pathway of plasma cell differentiation
Carmen Gómez‐Escolar, Alvaro Serrano‐Navarro, Alberto Benguria, Ana Dopazo, Fátima Sánchez‐Cabo, Almudena R Ramiro
EMBO Rep. 2022 Dec; 23(12): e55000. Published online 2022 Oct 7. doi: 10.15252/embr.202255000
PMCID:
PMC9724673
AbstractArticlePDF–3.8M
13.
Mucosal Plasma Cells are Required to Protect the Upper Airway and Brain from Infection
Sebastian A. Wellford, Annie Park Moseman, Kianna Dao, Katherine E. Wright, Allison Chen, Jona E. Plevin, Tzu-Chieh Liao, Naren Mehta, E. Ashley Moseman
Immunity. Author manuscript; available in PMC 2023 Nov 8.
Published in final edited form as: Immunity. 2022 Nov 8; 55(11): 2118–2134.e6. Published online 2022 Sep 21. doi: 10.1016/j.immuni.2022.08.017
PMCID:
PMC9649878
AbstractArticlePDF–1.3M
14.
The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes
Keith Conrad Fernandez, Laura Feeney, Ryan M Smolkin, Wei-Feng Yen, Allysia J Matthews, William Alread, John HJ Petrini, Jayanta Chaudhuri
eLife. 2022; 11: e77073. Published online 2022 Oct 3. doi: 10.7554/eLife.77073
PMCID:
PMC9581529
AbstractArticlePDF–11M
15.
The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways
Parakkal Jovvian George, Radu Marches, Djamel Nehar-Belaid, Jacques Banchereau, Sara Lustigman
Front Immunol. 2022; 13: 961094. Published online 2022 Sep 2. doi: 10.3389/fimmu.2022.961094
PMCID:
PMC9478378
AbstractArticlePDF–2.6M
16.
Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma
Grace M. Pindzola, Raud Razzaghi, Rachel N. Tavory, Hang T. Nguyen, Vivian M. Morris, Moyi Li, Shreya Agarwal, Bonnie Huang, Takaharu Okada, Hans C. Reinhardt, Gero Knittel, Hamid Kashkar, Ryan M. Young, Stefania Pittaluga, Jagan R. Muppidi
Blood. 2022 Sep 8; 140(10): 1119–1131. doi: 10.1182/blood.2022015926
PMCID:
PMC9461474
AbstractArticle
17.
AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination
Shin-ichi Tsukumo, Poorani Ganesh Subramani, Noé Seija, Mizuho Tabata, Yoichi Maekawa, Yuya Mori, Chieko Ishifune, Yasushi Itoh, Mineto Ota, Keishi Fujio, Javier M. Di Noia, Koji Yasutomo
Sci Adv. 2022 Aug; 8(34): eabq0008. Published online 2022 Aug 24. doi: 10.1126/sciadv.abq0008
PMCID:
PMC9401627
AbstractArticlePDF–1.8M
18.
Viral infection engenders bona fide and bystander subsets of lung-resident memory B cells through a permissive mechanism
Claude Gregoire, Lionel Spinelli, Sergio Villazala-Merino, Laurine Gil, María Pía Holgado, Myriam Moussa, Chuang Dong, Ana Zarubica, Mathieu Fallet, Jean-Marc Navarro, Bernard Malissen, Pierre Milpied, Mauro Gaya
Immunity. 2022 Jul 12; 55(7): 1216–1233.e9. Published online 2022 Jun 28. doi: 10.1016/j.immuni.2022.06.002
PMCID:
PMC9396418
AbstractArticlePDF–8.9M
19.
IgM-associated gut bacteria in obesity and type 2 diabetes in C57BL/6 mice and humans
James A. Pearson, Heyuan Ding, Changyun Hu, Jian Peng, Brittany Galuppo, F. Susan Wong, Sonia Caprio, Nicola Santoro, Li Wen
Diabetologia. 2022; 65(8): 1398–1411. Published online 2022 May 19. doi: 10.1007/s00125-022-05711-8
PMCID:
PMC9283171
AbstractArticlePDF–1.3M
20.
Switch Tandem Repeats Influence the Choice of the Alternative End-Joining Pathway in Immunoglobulin Class Switch Recombination
Chloé Oudinet, Xuefei Zhang, Nadine Puget, Nia Kyritsis, Claire Leduc, Fatima-Zohra Braikia, Audrey Dauba, Frederick W. Alt, Ahmed Amine Khamlichi
Front Immunol. 2022; 13: 870933. Published online 2022 May 16. doi: 10.3389/fimmu.2022.870933
PMCID:
PMC9149575
AbstractArticlePDF–5.0M

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