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Select item 109859971.

Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma

Fatih Yalcin, Hannah Haneke, Ibrahim E. Efe, Leonard D. Kuhrt, Edyta Motta, Bernadette Nickl, Charlotte Flüh, Michael Synowitz, Omar Dzaye, Michael Bader, Helmut Kettenmann

Acta Neuropathol Commun. 2024; 12: 50. Published online 2024 Apr 2. doi: 10.1186/s40478-024-01754-7

PMCID:: PMC10985997

Article PDF–3.2M

Select item 106004482.

Parvalbumin expression changes with retinal ganglion cell degeneration

Yuan Liu, Rossana Cheng He, Gustavo C. Munguba, Richard K. Lee

Front Neurosci. 2023; 17: 1227116. Published online 2023 Oct 12. doi: 10.3389/fnins.2023.1227116

PMCID:: PMC10600448

Article PDF–1.2M

Select item 103549443.

Single-cell transcriptome sequencing–based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis

Shaoqi Yang, Yuheng Sun, Min Long, Xinbei Zhou, Mengqin Yuan, Liliang Yang, Wei Luo, Yusi Cheng, Xinxin Zhang, Wei Jiang, Jie Chao

Part Fibre Toxicol. 2023; 20: 29. Published online 2023 Jul 19. doi: 10.1186/s12989-023-00543-9

PMCID:: PMC10354944

Article PDF–5.1M

Select item 91281674.

Tumor endothelial cell‐induced CD8⁺ T‐cell exhaustion via GPNMB in hepatocellular carcinoma

Yoshihiro Sakano, Takehiro Noda, Shogo Kobayashi, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Kunihito Gotoh, Hidenori Takahashi, Tadafumi Asaoka, Masahiro Tanemura, Hisashi Wada, Yuichiro Doki, Hidetoshi Eguchi

Cancer Sci. 2022 May; 113(5): 1625–1638. Published online 2022 Mar 24. doi: 10.1111/cas.15331

PMCID:: PMC9128167

Article PDF–4.2M

Select item 90213105.

Glycoprotein nonmetastatic melanoma protein B regulates lysosomal integrity and lifespan of senescent cells

Masayoshi Suda, Ippei Shimizu, Goro Katsuumi, Chieh Lun Hsiao, Yohko Yoshida, Naomi Matsumoto, Yutaka Yoshida, Akihiro Katayama, Jun Wada, Masahide Seki, Yutaka Suzuki, Shujiro Okuda, Kazuyuki Ozaki, Mayumi Nakanishi-Matsui, Tohru Minamino

Sci Rep. 2022; 12: 6522. Published online 2022 Apr 20. doi: 10.1038/s41598-022-10522-3

PMCID:: PMC9021310

Article PDF–2.3M

Select item 88504016.

The Contribution of Anterior Segment Abnormalities to Changes in Intraocular Pressure in the DBA/2J Mouse Model of Glaucoma: DBA/2J-Gpnmb⁺/SjJ Mice as Critical Controls

Landon J. Rohowetz, Marc E. Mardelli, R. Scott Duncan, Sean M. Riordan, Peter Koulen

Front Neurosci. 2021; 15: 801184. Published online 2022 Feb 3. doi: 10.3389/fnins.2021.801184

PMCID:: PMC8850401

Article PDF–3.8M

Select item 85241947.

GPNMB plays a protective role against obesity-related metabolic disorders by reducing macrophage inflammatory capacity

Adam Prabata, Koji Ikeda, Elda Putri Rahardini, Ken-Ichi Hirata, Noriaki Emoto

J Biol Chem. 2021 Nov; 297(5): 101232. Published online 2021 Sep 25. doi: 10.1016/j.jbc.2021.101232

PMCID:: PMC8524194

Article PDF–1.9M

Select item 84904528.

Anti-inflammatory role of Gpnmb in adipose tissue of mice

Bernadette Nickl, Fatimunnisa Qadri, Michael Bader

Sci Rep. 2021; 11: 19614. Published online 2021 Oct 4. doi: 10.1038/s41598-021-99090-6

PMCID:: PMC8490452

Article PDF–4.5M

Select item 81195019.

Quantitative trait locus mapping identifies the Gpnmb gene as a modifier of mouse macrophage lysosome function

Peggy Robinet, Brian Ritchey, Shuhui Wang Lorkowski, Alexander M. Alzayed, Sophia DeGeorgia, Eve Schodowski, C. Alicia Traughber, Jonathan D. Smith

Sci Rep. 2021; 11: 10249. Published online 2021 May 13. doi: 10.1038/s41598-021-89800-5

PMCID:: PMC8119501

Article PDF–2.4M

Select item 765675710.

Complement peptide C3a receptor 1 promotes optic nerve degeneration in DBA/2J mice

Jeffrey M. Harder, Pete A. Williams, Catherine E. Braine, Hongtian S. Yang, Jocelyn M. Thomas, Nicole E. Foxworth, Simon W. M. John, Gareth R. Howell

J Neuroinflammation. 2020; 17: 336. Published online 2020 Nov 11. doi: 10.1186/s12974-020-02011-z

PMCID:: PMC7656757

Article PDF–3.0M

Select item 741599111.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Article PDF–2.0M

Select item 740686212.

Changes in melatonin receptor expression in a murine model of glaucoma

Alejandro Martínez-Águila, Begoña Fonseca, María J. Pérez de Lara, M. Teresa Miras-Portugal, Rosa Gómez-Villafuertes, Gonzalo Carracedo, Jesús Pintor

Mol Vis. 2020; 26: 530–539. Published online 2020 Jul 29.

PMCID:: PMC7406862

Article PDF–1.4M

Select item 735659613.

An ocular glymphatic clearance system removes β-amyloid from the rodent eye

Xiaowei Wang, Nanhong Lou, Allison Eberhardt, Yujia Yang, Peter Kusk, Qiwu Xu, Benjamin Förstera, Sisi Peng, Meng Shi, Antonio Ladrón-de-Guevara, Christine Delle, Björn Sigurdsson, Anna L. R. Xavier, Ali Ertürk, Richard T. Libby, Lu Chen, Alexander S. Thrane, Maiken Nedergaard

Sci Transl Med. Author manuscript; available in PMC 2020 Jul 13.

Published in final edited form as: Sci Transl Med. 2020 Mar 25; 12(536): eaaw3210. doi: 10.1126/scitranslmed.aaw3210

PMCID:: PMC7356596

Article PDF–2.1M

Select item 724941214.

Ocular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA/2 J mice

James R. Tribble, Jeffrey M. Harder, Pete A. Williams, Simon W. M. John

Mol Brain. 2020; 13: 81. Published online 2020 May 25. doi: 10.1186/s13041-020-00603-7

PMCID:: PMC7249412

Article PDF–2.6M

Select item 667692515.

Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma

Rebecca A. Buchanan, Kate E. Foley, Keating W. Pepper, Alaina M. Reagan, Kelly J. Keezer, Amanda A. Hewes, Cory A. Diemler, Christoph Preuss, Ileana Soto, Simon W. M. John, Gareth R. Howell

Invest Ophthalmol Vis Sci. 2019 Aug; 60(10): 3283–3296. doi: 10.1167/iovs.18-26126

PMCID:: PMC6676925

Article PDF–2.3M

Select item 647824316.

Investigating a downstream gene of Gpnmb using the systems genetics method

Ye Lu, Diana Zhou, Hong Lu, Fuyi Xu, Junming Yue, Jianping Tong, Lu Lu

Mol Vis. 2019; 25: 222–236. Published online 2019 Apr 23.

PMCID:: PMC6478243

Article PDF–1.4M

Select item 633650417.

Developmental heterogeneity of microglia and brain myeloid cells revealed by deep single-cell RNA sequencing

Qingyun Li, Zuolin Cheng, Lu Zhou, Spyros Darmanis, Norma F. Neff, Jennifer Okamoto, Gunsagar Gulati, Mariko L. Bennett, Lu O. Sun, Laura E. Clarke, Julia Marschallinger, Guoqiang Yu, Stephen R. Quake, Tony Wyss-Coray, Ben A. Barres

Neuron. Author manuscript; available in PMC 2020 Jan 16.

Published in final edited form as: Neuron. 2019 Jan 16; 101(2): 207–223.e10. Published online 2018 Dec 31. doi: 10.1016/j.neuron.2018.12.006

PMCID:: PMC6336504

Article PDF–2.0M

Select item 608683018.

Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma

Huihui Chen, Kin-Sang Cho, T. H. Khanh Vu, Ching-Hung Shen, Mandeep Kaur, Guochun Chen, Rose Mathew, M. Lisa McHam, Ahad Fazelat, Kameran Lashkari, Ngan Pan Bennett Au, Joyce Ka Yu Tse, Yingqian Li, Honghua Yu, Lanbo Yang, Joan Stein-Streilein, Chi Him Eddie Ma, Clifford J. Woolf, Mark T. Whary, Martine J. Jager, James G. Fox, Jianzhu Chen, Dong F. Chen

Nat Commun. 2018; 9: 3209. Published online 2018 Aug 10. doi: 10.1038/s41467-018-05681-9

Correction in:: Nat Commun. 2018; 9: 3914.

PMCID:: PMC6086830

Article PDF–1.5M

Select item 602112819.

Mary P. Nivison, Nolan G. Ericson, Virginia M. Green, Jason H. Bielas, Jean S. Campbell, Philip J. Horner

Exp Neurol. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Exp Neurol. 2017 Oct; 296: 49–61. Published online 2017 Jul 3. doi: 10.1016/j.expneurol.2017.07.001

PMCID:: PMC6021128

Article PDF–980K

Select item 597744720.

Structural and Functional Rescue of Chronic Metabolically Stressed Optic Nerves through Respiration

Mohammad Harun-Or-Rashid, Nate Pappenhagen, Peter G. Palmer, Matthew A. Smith, Victoria Gevorgyan, Gina N. Wilson, Samuel D. Crish, Denise M. Inman

J Neurosci. 2018 May 30; 38(22): 5122–5139. doi: 10.1523/JNEUROSCI.3652-17.2018

PMCID:: PMC5977447

Article PDF–10M

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