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Select item 108702281.

INDUCTION OF A NOTCH3 LEHMAN SYNDROME MUTATION IN OSTEOCYTES CAUSES OSTEOPENIA IN MALE C57BL/6J MICE

E. Canalis, S.P. Yee, A.N. Economides, L. Schilling, J. Yu

Bone. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Bone. 2022 Sep; 162: 116476. Published online 2022 Jun 26. doi: 10.1016/j.bone.2022.116476

PMCID:: PMC10870228

Article PDF–1.8M

Select item 107867012.

Milagros C. Romay, Russell H. Knutsen, Feiyang Ma, Ana Mompeón, Gloria E. Hernandez, Jocelynda Salvador, Snezana Mirkov, Ayush Batra, David P. Sullivan, Daniele Procissi, Samuel Buchanan, Elise Kronquist, Elisa A. Ferrante, William A. Muller, Jordain Walshon, Alicia Steffens, Kathleen McCortney, Craig Horbinski, Elisabeth Tournier‑Lasserve, Adam M. Sonabend, Farzaneh A. Sorond, Michael M. Wang, Manfred Boehm, Beth A. Kozel, M. Luisa Iruela-Arispe

J Clin Invest. 2024 Jan 16; 134(2): e166134. Published online 2024 Jan 16. doi: 10.1172/JCI166134

PMCID:: PMC10786701

Article PDF–8.4M

Select item 105125593.

Nestin and Notch3 collaboratively regulate angiogenesis, collagen production, and endothelial–mesenchymal transition in lung endothelial cells

Wakako Daido, Taku Nakashima, Takeshi Masuda, Shinjiro Sakamoto, Kakuhiro Yamaguchi, Yasushi Horimasu, Shintaro Miyamoto, Hiroshi Iwamoto, Kazunori Fujitaka, Hironobu Hamada, Noboru Hattori

Cell Commun Signal. 2023; 21: 247. Published online 2023 Sep 21. doi: 10.1186/s12964-023-01099-z

PMCID:: PMC10512559

Article PDF–7.1M

Select item 104976274.

Left ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart

Francesca Del Gaudio, Dongli Liu, Maarja Andaloussi Mäe, Eike-Benjamin Braune, Emil M. Hansson, Qing-Dong Wang, Christer Betsholtz, Urban Lendahl

Sci Rep. 2023; 13: 15022. Published online 2023 Sep 12. doi: 10.1038/s41598-023-42010-7

PMCID:: PMC10497627

Article PDF–9.2M

Select item 103558065.

Notch3/Hes5 Induces Vascular Dysfunction in Hypoxia-Induced Pulmonary Hypertension Through ER Stress and Redox-Sensitive Pathways

Hannah E. Morris, Karla B. Neves, Margaret Nilsen, Augusto C. Montezano, Margaret R. MacLean, Rhian M. Touyz

Hypertension. 2023 Aug; 80(8): 1683–1696. Published online 2023 May 31. doi: 10.1161/HYPERTENSIONAHA.122.20449

PMCID:: PMC10355806

Article PDF–2.5M

Select item 101958066.

Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer

Maria Kondratyev, Aleksandra Pesic, Troy Ketela, Natalie Stickle, Christine Beswick, Zvi Shalev, Stefano Marastoni, Soroush Samadian, Anna Dvorkin-Gheva, Azin Sayad, Mikhail Bashkurov, Pedro Boasquevisque, Alessandro Datti, Trevor J. Pugh, Carl Virtanen, Jason Moffat, Reidar A. Grénman, Marianne Koritzinsky, Bradly G. Wouters

Commun Biol. 2023; 6: 538. Published online 2023 May 18. doi: 10.1038/s42003-023-04828-9

PMCID:: PMC10195806

Article PDF–2.9M

Select item 100231617.

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart

Valeria Taliani, Giulia Buonaiuto, Fabio Desideri, Adriano Setti, Tiziana Santini, Silvia Galfrè, Leonardo Schirone, Davide Mariani, Giacomo Frati, Valentina Valenti, Sebastiano Sciarretta, Emerald Perlas, Carmine Nicoletti, Antonio Musarò, Monica Ballarino

eLife. 2023; 12: e81360. Published online 2023 Mar 6. doi: 10.7554/eLife.81360

PMCID:: PMC10023161

Article PDF–4.8M

Select item 99752318.

Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer

Sonia Brahim, Ana-Maria Negulescu, Clara Geneste, Thomas Schott, Shuheng Lin, Louis-Oscar Morel, Nicolas Rama, Nicolas Gadot, Isabelle Treilleux, Patrick Mehlen, Olivier Meurette

Cell Death Dis. 2023 Feb; 14(2): 171. Published online 2023 Feb 28. doi: 10.1038/s41419-023-05674-7

PMCID:: PMC9975231

Article PDF–3.0M

Select item 97882319.

Deletion of Notch3 Impairs Contractility of Renal Resistance Vessels Due to Deficient Ca²⁺ Entry

Frank Helle, Michael Hultström, Panagiotis Kavvadas, Bjarne Iversen, Christos E. Chadjichristos, Christos Chatziantoniou

Int J Mol Sci. 2022 Dec; 23(24): 16068. Published online 2022 Dec 16. doi: 10.3390/ijms232416068

PMCID:: PMC9788231

Article PDF–1.8M

Select item 972074310.

Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility

Mariam Rusidzé, Mélanie C. Faure, Pierre Sicard, Isabelle Raymond-Letron, Frank Giton, Emilie Vessieres, Vincent Prevot, Daniel Henrion, Jean-François Arnal, Charlotte A. Cornil, Françoise Lenfant

Development. 2022 Oct 1; 149(19): dev200683. Published online 2022 Oct 13. doi: 10.1242/dev.200683

PMCID:: PMC9720743

Article

Select item 944503511.

MTG8 interacts with LHX6 to specify cortical interneuron subtype identity

Zeinab Asgarian, Marcio Guiomar Oliveira, Agata Stryjewska, Ioannis Maragkos, Anna Noren Rubin, Lorenza Magno, Vassilis Pachnis, Mohammadmersad Ghorbani, Scott Wayne Hiebert, Myrto Denaxa, Nicoletta Kessaris

Nat Commun. 2022; 13: 5217. Published online 2022 Sep 5. doi: 10.1038/s41467-022-32898-6

PMCID:: PMC9445035

Article PDF–10M

Select item 908991112.

Use of antisense oligonucleotides to target Notch3 in skeletal cells

Ernesto Canalis, Michele Carrer, Tabitha Eller, Lauren Schilling, Jungeun Yu

PLoS One. 2022; 17(5): e0268225. Published online 2022 May 10. doi: 10.1371/journal.pone.0268225

PMCID:: PMC9089911

Article PDF–2.1M

Select item 898800813.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju

J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787

PMCID:: PMC8988008

Article PDF–6.1M

Select item 888491114.

JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency

Jui M. Dave, Raja Chakraborty, Aglaia Ntokou, Junichi Saito, Fatima Z. Saddouk, Zhonghui Feng, Ashish Misra, George Tellides, Robert K. Riemer, Zsolt Urban, Caroline Kinnear, James Ellis, Seema Mital, Robert Mecham, Kathleen A. Martin, Daniel M. Greif

J Clin Invest. 2022 Mar 1; 132(5): e142338. Published online 2022 Mar 1. doi: 10.1172/JCI142338

PMCID:: PMC8884911

Article PDF–3.3M

Select item 886347815.

Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome

Kathryn Jespersen, Chenxin Li, Rishi Batra, Christopher A. Stephenson, Paul Harding, Kylie Sestak, Ryan T. Foley, Harrison Greene, Trevor Meisinger, Jason R. Cook, B. Timothy Baxter, Wanfen Xiong

J Immunol Res. 2022; 2022: 7538649. Published online 2022 Feb 15. doi: 10.1155/2022/7538649

PMCID:: PMC8863478

Article PDF–1.0M

Select item 877890516.

Activation of Notch3 in Renal Tubular Cells Leads to Progressive Cystic Kidney Disease

Sonja Djudjaj, Panagiotis Kavvadas, Niki Prakoura, Roman D. Bülow, Tiffany Migeon, Sandrine Placier, Christos E. Chadjichristos, Peter Boor, Christos Chatziantoniou

Int J Mol Sci. 2022 Jan; 23(2): 884. Published online 2022 Jan 14. doi: 10.3390/ijms23020884

PMCID:: PMC8778905

Article PDF–4.4M

Select item 861717617.

Cell-fate transition and determination analysis of mouse male germ cells throughout development

Jiexiang Zhao, Ping Lu, Cong Wan, Yaping Huang, Manman Cui, Xinyan Yang, Yuqiong Hu, Yi Zheng, Ji Dong, Mei Wang, Shu Zhang, Zhaoting Liu, Shuhui Bian, Xiaoman Wang, Rui Wang, Shaofang Ren, Dazhuang Wang, Zhaokai Yao, Gang Chang, Fuchou Tang, Xiao-Yang Zhao

Nat Commun. 2021; 12: 6839. Published online 2021 Nov 25. doi: 10.1038/s41467-021-27172-0

PMCID:: PMC8617176

Article PDF–14M

Select item 821522518.

Adamts18 modulates the development of the aortic arch and common carotid artery

Shuai Ye, Ning Yang, Tiantian Lu, Taojing Wu, Liya Wang, Yi-Hsuan Pan, Xiaohua Cao, Xiaobing Yuan, Thomas Wisniewski, Suying Dang, Wei Zhang

iScience. 2021 Jun 25; 24(6): 102672. Published online 2021 May 31. doi: 10.1016/j.isci.2021.102672

PMCID:: PMC8215225

Article PDF–8.9M

Select item 808614519.

Activation of Notch3 in osteoblasts/osteocytes causes compartment-specific changes in bone remodeling

Ernesto Canalis, Stefano Zanotti, Lauren Schilling, Tabitha Eller, Jungeun Yu

J Biol Chem. 2021 Jan-Jun; 296: 100583. Published online 2021 Mar 24. doi: 10.1016/j.jbc.2021.100583

PMCID:: PMC8086145

Article PDF–5.8M

Select item 793877020.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

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