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Select item 94819331.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 81579572.

AP-3–dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells

Seunghyi Kook, Ping Wang, Shufang Meng, Christopher S. Jetter, Jennifer M. S. Sucre, John T. Benjamin, Jason J. Gokey, Hayley A. Hanby, Alexa Jaume, Laura Goetzl, Michael S. Marks, Susan H. Guttentag

Proc Natl Acad Sci U S A. 2021 May 18; 118(20): e2025208118. Published online 2021 May 14. doi: 10.1073/pnas.2025208118

PMCID:: PMC8157957

Abstract Article PDF–1.9M

Select item 80202683.

A zinc transporter, transmembrane protein 163, is critical for the biogenesis of platelet dense granules

Yefeng Yuan, Teng Liu, Xiahe Huang, Yuanying Chen, Weilin Zhang, Ting Li, Lin Yang, Quan Chen, Yingchun Wang, Aihua Wei, Wei Li

Blood. 2021 Apr 1; 137(13): 1804–1817. Prepublished online 2021 Jan 29. doi: 10.1182/blood.2020007389

PMCID:: PMC8020268

Abstract Article

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78715905.

Hermansky-Pudlak syndrome-2 alters mitochondrial homeostasis in the alveolar epithelium of the lung

Karina Cuevas-Mora, Willy Roque, Hoora Shaghaghi, Bernadette R. Gochuico, Ivan O. Rosas, Ross Summer, Freddy Romero

Respir Res. 2021; 22: 49. Published online 2021 Feb 8. doi: 10.1186/s12931-021-01640-z

PMCID:: PMC7871590

Abstract Article PDF–2.0M

Select item 71362326.

Synaptic ribbons foster active zone stability and illumination-dependent active zone enrichment of RIM2 and Cav1.4 in photoreceptor synapses

Ekta Dembla, Mayur Dembla, Stephan Maxeiner, Frank Schmitz

Sci Rep. 2020; 10: 5957. Published online 2020 Apr 6. doi: 10.1038/s41598-020-62734-0

PMCID:: PMC7136232

Abstract Article PDF–8.4M

Select item 67638747.

The Neuronal Form of Adaptor Protein-3 Is Required for Synaptic Vesicle Formation from Endosomes

Jessica Blumstein, Victor Faundez, Fubito Nakatsu, Takashi Saito, Hiroshi Ohno, Regis B. Kelly

J Neurosci. 2001 Oct 15; 21(20): 8034–8042. doi: 10.1523/JNEUROSCI.21-20-08034.2001

PMCID:: PMC6763874

Abstract Article PDF–526K

Select item 66109468.

Matrix metalloproteinase activity in the lung is increased in Hermansky-Pudlak syndrome

Ross Summer, Rachana Krishna, DeLeila Schriner, Karina Cuevas-Mora, Dominic Sales, Rachel Para, Jesse Roman, Carl Nieweld, Bernadette R. Gochuico, Freddy Romero

Orphanet J Rare Dis. 2019; 14: 162. Published online 2019 Jul 4. doi: 10.1186/s13023-019-1143-0

PMCID:: PMC6610946

Abstract Article PDF–2.1M

Select item 65642249.

Characterization of abnormalities in the visual system of the mutant mouse pearl

GW Balkema, Jr, LH Pinto, UC Drager, JW Vanable, Jr

J Neurosci. 1981 Nov 1; 1(11): 1320–1329. doi: 10.1523/JNEUROSCI.01-11-01320.1981

PMCID:: PMC6564224

Abstract PDF–1.9M

Select item 624418310.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 616613211.

Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection

Elena Tomasello, Karima Naciri, Rabie Chelbi, Gilles Bessou, Anissa Fries, Elise Gressier, Abdenour Abbas, Emeline Pollet, Philippe Pierre, Toby Lawrence, Thien‐Phong Vu Manh, Marc Dalod

EMBO J. 2018 Oct 1; 37(19): e98836. Published online 2018 Aug 21. doi: 10.15252/embj.201798836

PMCID:: PMC6166132

Abstract Article PDF–3.2M

Select item 594633312.

Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes

Seunghyi Kook, Aidong Qi, Ping Wang, Shufang Meng, Peter Gulleman, Lisa R. Young, Susan H. Guttentag

Am J Respir Cell Mol Biol. 2018 May; 58(5): 566–574. doi: 10.1165/rcmb.2017-0324MA

PMCID:: PMC5946333

Abstract Article PDF–1.1M

Select item 569810713.

Induction of Systemic Autoimmunity by Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome/Endolysosome but Not Type I IFN

K. Michael Pollard, Gabriela M. Escalante, Hua Huang, Katarina M. Haraldsson, Per Hultman, Joseph M. Christy, Rahul D. Pawar, Jessica M. Mayeux, Rosana Gonzalez-Quintial, Roberto Baccala, Bruce Beutler, Argyrios N. Theofilopoulos, Dwight H. Kono

J Immunol. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: J Immunol. 2017 Dec 1; 199(11): 3739–3747. Published online 2017 Oct 20. doi: 10.4049/jimmunol.1700332

PMCID:: PMC5698107

Abstract Article PDF–904K

Select item 547289914.

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8⁺ T cells

Geoffrey L. Rogers, Jamie L. Shirley, Irene Zolotukhin, Sandeep R. P. Kumar, Alexandra Sherman, George Q. Perrin, Brad E. Hoffman, Arun Srivastava, Etiena Basner-Tschakarjan, Mark A. Wallet, Cox Terhorst, Moanaro Biswas, Roland W. Herzog

Blood. 2017 Jun 15; 129(24): 3184–3195. Prepublished online 2017 May 3. doi: 10.1182/blood-2016-11-751040

PMCID:: PMC5472899

Abstract Article

Select item 546827615.

RIM1/2 in retinal ganglion cells are required for the refinement of ipsilateral axons and eye-specific segregation

Ahlem Assali, Corentin Le Magueresse, Mohamed Bennis, Xavier Nicol, Patricia Gaspar, Alexandra Rebsam

Sci Rep. 2017; 7: 3236. Published online 2017 Jun 12. doi: 10.1038/s41598-017-03361-0

PMCID:: PMC5468276

Abstract Article PDF–6.2M

Select item 507095516.

Epithelial-macrophage interactions determine pulmonary fibrosis susceptibility in Hermansky-Pudlak syndrome

Lisa R. Young, Peter M. Gulleman, Chelsi W. Short, Harikrishna Tanjore, Taylor Sherrill, Aidong Qi, Andrew P. McBride, Rinat Zaynagetdinov, John T. Benjamin, William E. Lawson, Sergey V. Novitskiy, Timothy S. Blackwell

JCI Insight. 2016 Oct 20; 1(17): e88947. Published online 2016 Oct 20. doi: 10.1172/jci.insight.88947

PMCID:: PMC5070955

Abstract Article PDF–1.6M

Select item 493855917.

Human Immunodeficiency Virus Type 2 (HIV-2) Gag Is Trafficked in an AP-3 and AP-5 Dependent Manner

Justine E. Alford, Michela Marongiu, Gemma L. Watkins, Emma C. Anderson

PLoS One. 2016; 11(7): e0158941. Published online 2016 Jul 8. doi: 10.1371/journal.pone.0158941

PMCID:: PMC4938559

Abstract Article PDF–12M

Select item 488855418.

MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro

Saket Ahuja, Lars Knudsen, Shashi Chillappagari, Ingrid Henneke, Clemens Ruppert, Martina Korfei, Bernadette R. Gochuico, Saverio Bellusci, Werner Seeger, Matthias Ochs, Andreas Guenther, Poornima Mahavadi

Am J Physiol Lung Cell Mol Physiol. 2016 Mar 15; 310(6): L519–L531. Published online 2015 Dec 30. doi: 10.1152/ajplung.00213.2015

PMCID:: PMC4888554

Abstract Article

Select item 486141619.

Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice

Seunghyi Kook, Ping Wang, Lisa R. Young, Michael Schwake, Paul Saftig, Xialian Weng, Ying Meng, Dante Neculai, Michael S. Marks, Linda Gonzales, Michael F. Beers, Susan Guttentag

J Biol Chem. 2016 Apr 15; 291(16): 8414–8427. Published online 2016 Feb 23. doi: 10.1074/jbc.M116.720201

PMCID:: PMC4861416

Abstract Article PDF–2.1M

Select item 461086320.

AP-3 mediated trafficking of TLR2 ligands controls specificity of inflammatory responses but not adaptor complex assembly

Tanja Petnicki-Ocwieja, Aurelie Kern, Tess L. Killpack, Stephen C. Bunnell, Linden T. Hu

J Immunol. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: J Immunol. 2015 Nov 1; 195(9): 4331–4340. Published online 2015 Sep 30. doi: 10.4049/jimmunol.1501268

PMCID:: PMC4610863

Abstract Article PDF–856K

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