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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 106176252.

Caudal Fgfr1 disruption produces localised spinal mis-patterning and a terminal myelocystocele-like phenotype in mice

Eirini Maniou, Faduma Farah, Abigail R. Marshall, Zoe Crane-Smith, Andrea Krstevski, Athanasia Stathopoulou, Nicholas D. E. Greene, Andrew J. Copp, Gabriel L. Galea

Development. 2023 Oct 1; 150(19): dev202139. Published online 2023 Oct 10. doi: 10.1242/dev.202139

PMCID:: PMC10617625

Abstract Article

Select item 105837503.

MiRNA-470-5p suppresses epithelial-mesenchymal transition of embryonic palatal shelf epithelial cells by targeting Fgfr1 during palatogenesis

Jieyan Zhou, Ming Zhang, Mingjun Zhang, Mengxia Tan, Yingwen Ji, Shenyou Shu, Yan Liang

Exp Biol Med (Maywood) 2023 Jul; 248(13): 1124–1133. Published online 2023 Aug 1. doi: 10.1177/15353702231182215

PMCID:: PMC10583750

Abstract Article PDF–2.9M

Select item 105768114.

FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation

Marit H. Aure, Jennifer M. Symonds, Carlos U. Villapudua, Joshua T. Dodge, Sabine Werner, Wendy M. Knosp, Matthew P. Hoffman

Nat Commun. 2023; 14: 6485. Published online 2023 Oct 14. doi: 10.1038/s41467-023-42243-0

PMCID:: PMC10576811

Abstract Article PDF–17M

Select item 104355625.

VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway

Chunsik Lee, Rongyuan Chen, Guangli Sun, Xialin Liu, Xianchai Lin, Chang He, Liying Xing, Lixian Liu, Lasse D. Jensen, Anil Kumar, Harald F. Langer, Xiangrong Ren, Jianing Zhang, Lijuan Huang, Xiangke Yin, JongKyong Kim, Juanhua Zhu, Guanqun Huang, Jiani Li, Weiwei Lu, Wei Chen, Juanxi Liu, Jiaxin Hu, Qihang Sun, Weisi Lu, Lekun Fang, Shasha Wang, Haiqing Kuang, Yihan Zhang, Geng Tian, Jia Mi, Bi-Ang Kang, Masashi Narazaki, Aaron Prodeus, Luc Schoonjans, David M. Ornitz, Jean Gariepy, Guy Eelen, Mieke Dewerchin, Yunlong Yang, Jing-Song Ou, Antonio Mora, Jin Yao, Chen Zhao, Yizhi Liu, Peter Carmeliet, Yihai Cao, Xuri Li

Signal Transduct Target Ther. 2023; 8: 305. Published online 2023 Aug 18. doi: 10.1038/s41392-023-01539-9

PMCID:: PMC10435562

Abstract Article PDF–4.9M

Select item 104036406.

Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth

Kanako Kobayashi, Kazuko Iwasa, Rika Azuma-Suzuki, Takeshi Kawauchi, Yo-ichi Nabeshima

Life Sci Alliance. 2023 Oct; 6(10): e202301916. Published online 2023 Aug 4. doi: 10.26508/lsa.202301916

PMCID:: PMC10403640

Abstract Article PDF–2.1M

Select item 101672577.

FGF21-FGFR1 controls mitochondrial homeostasis in cardiomyocytes by modulating the degradation of OPA1

Bing Yan, Zhu Mei, Yaohan Tang, Haixu Song, Hanlin Wu, Quanmin Jing, Xiaolin Zhang, Chenghui Yan, Yaling Han

Cell Death Dis. 2023 May; 14(5): 311. Published online 2023 May 8. doi: 10.1038/s41419-023-05842-9

PMCID:: PMC10167257

Abstract Article PDF–7.5M

Select item 101214688.

Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia

Sophie Patzek, Zhe Liu, Sean de la O, Sean Chang, Lauren E. Byrnes, Xiuqin Zhang, David M. Ornitz, Julie B. Sneddon

iScience. 2023 Apr 21; 26(4): 106500. Published online 2023 Mar 25. doi: 10.1016/j.isci.2023.106500

PMCID:: PMC10121468

Abstract Article PDF–12M

Select item 101129189.

FGF signaling regulates salivary gland branching morphogenesis by modulating cell adhesion

Ayan T. Ray, Philippe Soriano

Development. 2023 Mar 15; 150(6): dev201293. Published online 2023 Mar 20. doi: 10.1242/dev.201293

PMCID:: PMC10112918

Abstract Article

Select item 1003675410.

Deficiency of endothelial FGFR1 signaling via upregulation of ROCK2 activity aggravated ALI/ARDS

Yue Deng, Xingming Huang, Yan Hu, Weiting Zhong, Hua Zhang, Chunheng Mo, Hongjun Wang, Bi-Sen Ding, Chen Wang

Front Immunol. 2023; 14: 1041533. Published online 2023 Mar 10. doi: 10.3389/fimmu.2023.1041533

PMCID:: PMC10036754

Abstract Article PDF–27M

Select item 991843011.

Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1

Abigail S. Coetzee, Edward P. Carter, Lucía Rodríguez-Fernández, James Heward, Qiaoying Wang, Saadia A. Karim, Lina Boughetane, Christopher Milton, Firat Uyulur, Jennifer P. Morton, Hemant M. Kocher, Richard P. Grose

Oncogene. 2023; 42(7): 491–500. Published online 2022 Nov 10. doi: 10.1038/s41388-022-02513-5

Correction in:: Oncogene. 2023; 42(7): 545.

PMCID:: PMC9918430

Abstract Article PDF–3.9M

Select item 977136512.

TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development

Jifan Feng, Xia Han, Yuan Yuan, Courtney Kyeong Cho, Eva Janečková, Tingwei Guo, Siddhika Pareek, Md Shaifur Rahman, Banghong Zheng, Jing Bi, Junjun Jing, Mingyi Zhang, Jian Xu, Thach-Vu Ho, Yang Chai

eLife. 2022; 11: e80405. Published online 2022 Dec 21. doi: 10.7554/eLife.80405

PMCID:: PMC9771365

Abstract Article PDF–17M

Select item 975933113.

Convergent biological pathways underlying the Kallmann syndrome-linked genes Hs6st1 and Fgfr1

Sohyun Moon, Ying-Tao Zhao

Hum Mol Genet. 2022 Dec 15; 31(24): 4207–4216. Published online 2022 Jul 28. doi: 10.1093/hmg/ddac172

PMCID:: PMC9759331

Abstract Article PDF–1.3M

Select item 971647214.

Deficiency of endothelial FGFR1 alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice

Yanrong Long, Hongbin Chen, Junchao Deng, Junjie Ning, Pengbo Yang, Lina Qiao, Zhongwei Cao

Front Pharmacol. 2022; 13: 1039103. Published online 2022 Nov 18. doi: 10.3389/fphar.2022.1039103

PMCID:: PMC9716472

Abstract Article PDF–5.8M

Select item 966714315.

Paracrine interactions through FGFR1 and FGFR2 receptors regulate the development of preimplantation mouse chimaeric embryo

Katarzyna Krawczyk, Katarzyna Wilczak, Katarzyna Szczepańska, Marek Maleszewski, Aneta Suwińska

Open Biol. 2022 Nov; 12(11): 220193. Published online November 16, 2022. doi: 10.1098/rsob.220193

PMCID:: PMC9667143

Abstract Article PDF–1.6M

Select item 924561916.

FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesis

Xiaolong Zhu, Cong Qiu, Yiran Wang, Yuanqing Jiang, Yefeng Chen, Linge Fan, Ruizhe Ren, Yunyun Wang, Yu Chen, Yanzhi Feng, Xiaofei Zhou, Yunhui Zhu, Zhen Ge, Dongwu Lai, Lingfeng Qin, Michael Simons, Luyang Yu

Proc Natl Acad Sci U S A. 2022 Jun 28; 119(26): e2202631119. Published online 2022 Jun 21. doi: 10.1073/pnas.2202631119

PMCID:: PMC9245619

Abstract Article PDF–5.6M

Select item 921355217.

NANOG initiates epiblast fate through the coordination of pluripotency genes expression

Nicolas Allègre, Sabine Chauveau, Cynthia Dennis, Yoan Renaud, Dimitri Meistermann, Lorena Valverde Estrella, Pierre Pouchin, Michel Cohen-Tannoudji, Laurent David, Claire Chazaud

Nat Commun. 2022; 13: 3550. Published online 2022 Jun 21. doi: 10.1038/s41467-022-30858-8