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Items: 1 to 20 of 36

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Conditional Ablation of Spred1 and Spred2 in the Eye Lens Negatively Impacts Its Development and Growth
Fatima Wazin, Frank J. Lovicu
Cells. 2024 Feb; 13(4): 290. Published online 2024 Feb 6. doi: 10.3390/cells13040290
PMCID:
PMC10886530
AbstractArticlePDF–14M
3.
SPRED2 loss-of-function causes a recessive Noonan syndrome-like phenotype
Marialetizia Motta, Giulia Fasano, Sina Gredy, Julia Brinkmann, Adeline Alice Bonnard, Pelin Ozlem Simsek-Kiper, Elif Yilmaz Gulec, Leila Essaddam, Gulen Eda Utine, Ingrid Guarnetti Prandi, Martina Venditti, Francesca Pantaleoni, Francesca Clementina Radio, Andrea Ciolfi, Stefania Petrini, Federica Consoli, Cédric Vignal, Denis Hepbasli, Melanie Ullrich, Elke de Boer, Lisenka E.L.M. Vissers, Sami Gritli, Cesare Rossi, Alessandro De Luca, Saayda Ben Becher, Bruce D. Gelb, Bruno Dallapiccola, Antonella Lauri, Giovanni Chillemi, Kai Schuh, Hélène Cavé, Martin Zenker, Marco Tartaglia
Am J Hum Genet. 2021 Nov 4; 108(11): 2112–2129. Published online 2021 Oct 8. doi: 10.1016/j.ajhg.2021.09.007
PMCID:
PMC8595899
AbstractArticlePDF–2.6M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
Spred2-deficiency enhances the proliferation of lung epithelial cells and alleviates pulmonary fibrosis induced by bleomycin
Akina Kawara, Ryo Mizuta, Masayoshi Fujisawa, Toshihiro Ito, Chunning Li, Kaoru Nakamura, Cuiming Sun, Masaki Kuwabara, Masahiro Kitabatake, Teizo Yoshimura, Akihiro Matsukawa
Sci Rep. 2020; 10: 16490. Published online 2020 Oct 5. doi: 10.1038/s41598-020-73752-3
PMCID:
PMC7536438
AbstractArticlePDF–2.0M
6.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
7.
Spred2 Regulates High Fat Diet-Induced Adipose Tissue Inflammation, and Metabolic Abnormalities in Mice
Takahiro Ohkura, Teizo Yoshimura, Masayoshi Fujisawa, Toshiaki Ohara, Rie Marutani, Kaya Usami, Akihiro Matsukawa
Front Immunol. 2019; 10: 17. Published online 2019 Jan 22. doi: 10.3389/fimmu.2019.00017
PMCID:
PMC6349710
AbstractArticlePDF–2.0M
8.
Negative Regulation of Lens Fiber Cell Differentiation by RTK Antagonists Spry and Spred
Guannan Zhao, Charles G. Bailey, Yue Feng, John Rasko, Frank J. Lovicu
Exp Eye Res. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: Exp Eye Res. 2018 May; 170: 148–159. Published online 2018 Mar 1. doi: 10.1016/j.exer.2018.02.025
PMCID:
PMC5924633
AbstractArticlePDF–1.7M
9.
OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency
M Ullrich, M Weber, A M Post, S Popp, J Grein, M Zechner, H Guerrero González, A Kreis, A G Schmitt, N Üçeyler, K-P Lesch, K Schuh
Mol Psychiatry. 2018 Feb; 23(2): 444–458. Published online 2017 Jan 10. doi: 10.1038/mp.2016.232
PMCID:
PMC5794898
AbstractArticlePDF–669K
10.
Spred2 Deficiency Exacerbates D-Galactosamine/Lipopolysaccharide -induced Acute Liver Injury in Mice via Increased Production of TNFα
Xu Yang, Masayoshi Fujisawa, Teizo Yoshimura, Toshiaki Ohara, Miwa Sato, Megumi Mino, Thar Htet San, Tong Gao, Steven L. Kunkel, Akihiro Matsukawa
Sci Rep. 2018; 8: 188. Published online 2018 Jan 9. doi: 10.1038/s41598-017-18380-0
PMCID:
PMC5760641
AbstractArticlePDF–4.9M
11.
Spred2-deficiecy Protects Mice from Polymicrobial Septic Peritonitis by Enhancing Inflammation and Bacterial Clearance
Junya Itakura, Miwa Sato, Toshihiro Ito, Megumi Mino, Soichiro Fushimi, Sakuma Takahashi, Teizo Yoshimura, Akihiro Matsukawa
Sci Rep. 2017; 7: 12833. Published online 2017 Oct 9. doi: 10.1038/s41598-017-13204-7
PMCID:
PMC5634500
AbstractArticlePDF–2.2M
12.
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development
Elisabeth A. Rutledge, Jean-Denis Benazet, Andrew P. McMahon
Development. 2017 Sep 1; 144(17): 3177–3188. doi: 10.1242/dev.149112
PMCID:
PMC5611955
AbstractArticle
13.
Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia
Xin Heng, Qiuxia Guo, Alan W Leung, James YH Li
eLife. 2017; 6: e23253. Published online 2017 May 10. doi: 10.7554/eLife.23253
PMCID:
PMC5457141
AbstractArticlePDF–11M
14.
A Novel Role of Spred2 in the Colonic Epithelial Cell Homeostasis and Inflammation
Sakuma Takahashi, Teizo Yoshimura, Takahiro Ohkura, Masayoshi Fujisawa, Soichiro Fushimi, Toshihiro Ito, Junya Itakura, Sakiko Hiraoka, Hiroyuki Okada, Kazuhide Yamamoto, Akihiro Matsukawa
Sci Rep. 2016; 6: 37531. Published online 2016 Nov 21. doi: 10.1038/srep37531
PMCID:
PMC5116627
AbstractArticlePDF–1.6M
15.
FGFR2 mutation in 46,XY sex reversal with craniosynostosis
Stefan Bagheri-Fam, Makoto Ono, Li Li, Liang Zhao, Janelle Ryan, Raymond Lai, Yukako Katsura, Fernando J. Rossello, Peter Koopman, Gerd Scherer, Oliver Bartsch, Jacob V.P. Eswarakumar, Vincent R. Harley
Hum Mol Genet. 2015 Dec 1; 24(23): 6699–6710. Published online 2015 Sep 11. doi: 10.1093/hmg/ddv374
PMCID:
PMC4634374
AbstractArticlePDF–835K
16.
Cosuppression of Sprouty and Sprouty-Related Negative Regulators of FGF Signalling in Prostate Cancer: A Working Hypothesis
Stephen J. Assinder, Daniella Beniamen, Frank J. Lovicu
Biomed Res Int. 2015; 2015: 827462. Published online 2015 May 17. doi: 10.1155/2015/827462
PMCID:
PMC4449890
AbstractArticlePDF–6.3M
17.
Spred-2 Deficiency Exacerbates Lipopolysaccharide-Induced Acute Lung Inflammation in Mice
Yang Xu, Toshihiro Ito, Soichiro Fushimi, Sakuma Takahashi, Junya Itakura, Ryojiro Kimura, Miwa Sato, Megumi Mino, Akihiko Yoshimura, Akihiro Matsukawa
PLoS One. 2014; 9(10): e108914. Published online 2014 Oct 2. doi: 10.1371/journal.pone.0108914
PMCID:
PMC4183529
AbstractArticlePDF–2.5M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Identification of SPRED2 (Sprouty-related Protein with EVH1 Domain 2) as a Negative Regulator of the Hypothalamic-Pituitary-Adrenal Axis
Melanie Ullrich, Karin Bundschu, Peter M. Benz, Marco Abesser, Ruth Freudinger, Tobias Fischer, Julia Ullrich, Thomas Renné, Ulrich Walter, Kai Schuh
J Biol Chem. 2011 Mar 18; 286(11): 9477–9488. Published online 2011 Jan 3. doi: 10.1074/jbc.M110.171306
PMCID:
PMC3059030
AbstractArticlePDF–2.6M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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