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Select item 108156721.

Tribbles Genes in Gastric Cancer: A Tumor-Suppressive Role for TRIB2

Alessia Foscarini, Rossella Tricarico, Federica Gentile, Swapna Satam, Hermine Mohr, Endre Kiss-Toth, Guglielmina Nadia Ranzani, Natalia Simona Pellegata

Genes (Basel) 2024 Jan; 15(1): 26. Published online 2023 Dec 23. doi: 10.3390/genes15010026

PMCID:: PMC10815672

Abstract Article PDF–2.7M

Select item 101518262.

Upregulation of Tribbles decreases body weight and increases sleep duration

Rebeka Popovic, Yizhou Yu, Nuno Santos Leal, Giorgio Fedele, Samantha H. Y. Loh, L. Miguel Martins

Dis Model Mech. 2023 Apr 1; 16(4): dmm049942. Published online 2023 Apr 21. doi: 10.1242/dmm.049942

PMCID:: PMC10151826

Abstract Article

Select item 101187473.

TRIB2 safeguards naive T cell homeostasis during aging

Wenqiang Cao, Ines Sturmlechner, Huimin Zhang, Jun Jin, Bin Hu, Rohit R. Jadhav, Fengqin Fang, Cornelia M. Weyand, Jörg J. Goronzy

Cell Rep. Author manuscript; available in PMC 2023 Apr 20.

Published in final edited form as: Cell Rep. 2023 Mar 28; 42(3): 112195. Published online 2023 Mar 6. doi: 10.1016/j.celrep.2023.112195

PMCID:: PMC10118747

Abstract Article PDF–3.0M

Select item 98968444.

Polymorphisms in TRIB2 and CAPRIN2 Genes Contribute to the Susceptibility to High Myopia-Induced Cataract in Han Chinese Population

Bo Ma, Wenpei Zhang, Xiaochen Wang, Huili Jiang, Li Tang, Wen Yang, Qianyan Kang, Juan Cao

Med Sci Monit. 2023; 29: e937702-1–e937702-15. Prepublished online 2023 Jan 3. Published online 2023 Jan 30. doi: 10.12659/MSM.937702

PMCID:: PMC9896844

Abstract Article PDF–1.2M

Select item 85032625.

RFWD2 Knockdown as a Blocker to Reverse the Oncogenic Role of TRIB2 in Lung Adenocarcinoma

Ruimin Hao, Jinxia Hu, Yuemei Liu, Dongmin Liang, Yan-Mei Li, Ranran Wang, Shucui Zhang, Pingyu Wang, You-Jie Li, Shuyang Xie

Front Oncol. 2021; 11: 733175. Published online 2021 Sep 27. doi: 10.3389/fonc.2021.733175

PMCID:: PMC8503262

Abstract Article PDF–5.7M

Select item 84411426.

A methyltransferase‐like 14/miR‐99a‐5p/tribble 2 positive feedback circuit promotes cancer stem cell persistence and radioresistance via histone deacetylase 2‐mediated epigenetic modulation in esophageal squamous cell carcinoma

Zhenchuan Liu, Kaiqing Wu, Shaorui Gu, Wenli Wang, Shiliang Xie, Tiancheng Lu, Lei Li, Chenglai Dong, Xishi Wang, Yongxin Zhou

Clin Transl Med. 2021 Sep; 11(9): e545. Published online 2021 Sep 15. doi: 10.1002/ctm2.545

Correction in:: Clin Transl Med. 2022 Jun; 12(6): e741.

PMCID:: PMC8441142

Abstract Article PDF–4.8M

Select item 83343527.

TRIB2 Stimulates Cancer Stem-Like Properties through Activating the AKT-GSK3β-β-Catenin Signaling Axis

Dae Kyoung Kim, Yu Na Kim, Ye Eun Kim, Seo Yul Lee, Min Joo Shin, Eun Kyoung Do, Kyung-Un Choi, Seung-Chul Kim, Ki-Hyung Kim, Dong-Soo Suh, Parkyong Song, Jae Ho Kim

Mol Cells. 2021 Jul 31; 44(7): 481–492. Published online 2021 Jul 28. doi: 10.14348/molcells.2021.0030

PMCID:: PMC8334352

Abstract Article PDF–5.7M

Select item 82034538.

Stabilization of fatty acid synthesis enzyme acetyl-CoA carboxylase 1 suppresses acute myeloid leukemia development

Hidenori Ito, Ikuko Nakamae, Jun-ya Kato, Noriko Yoneda-Kato

J Clin Invest. 2021 Jun 15; 131(12): e141529. Published online 2021 Jun 15. doi: 10.1172/JCI141529

PMCID:: PMC8203453

Abstract Article PDF–8.8M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 779112010.

TRIB2 modulates proteasome function to reduce ubiquitin stability and protect liver cancer cells against oxidative stress

Susu Guo, Yuxin Chen, Yueyue Yang, Xiao Zhang, Lifang Ma, Xiangfei Xue, Yongxia Qiao, Jiayi Wang

Cell Death Dis. 2021 Jan; 12(1): 42. Published online 2021 Jan 7. doi: 10.1038/s41419-020-03299-8

PMCID:: PMC7791120

Abstract Article PDF–4.4M

Select item 747614011.

TRIM21 causes abnormal expression of IL-6 in oral lichen planus via the TRIB2-MAPK signal axis

Chenyan Jiang, Wei Wei, Yufeng Wang, Chencheng Song, Lei Pan, Kai Sun, Guanhuan Du, Yiwen Deng, Guoyao Tang

Am J Transl Res. 2020; 12(8): 4648–4658. Published online 2020 Aug 15.

PMCID:: PMC7476140

Abstract Article PDF–1.3M

Select item 742732712.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 716998313.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 705323114.

Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma

Jia Wang, Jie Zuo, Alafate Wahafu, Mao‐de Wang, Rui‐chun Li, Wan‐fu Xie

CNS Neurosci Ther. 2020 Mar; 26(3): 297–308. Published online 2019 Jul 18. doi: 10.1111/cns.13197

PMCID:: PMC7053231

Abstract Article PDF–2.7M

Select item 629199215.

TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling

Zhenlin Hou, Kaixuan Guo, Xuling Sun, Fuqing Hu, Qianzhi Chen, Xuelai Luo, Guihua Wang, Junbo Hu, Li Sun

Mol Cancer. 2018; 17: 172. Published online 2018 Dec 12. doi: 10.1186/s12943-018-0922-x

PMCID:: PMC6291992

Abstract Article PDF–3.1M

Select item 616668216.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 570419317.

Trib2 regulates the pluripotency of embryonic stem cells and enhances reprogramming efficiency

Eun Kyoung Do, Jae Kyung Park, Hyo Cheon Cheon, Yang Woo Kwon, Soon Chul Heo, Eun Jung Choi, Jeong Kon Seo, Il Ho Jang, Sang Chul Lee, Jae Ho Kim

Exp Mol Med. 2017 Nov; 49(11): e401. Published online 2017 Nov 24. doi: 10.1038/emm.2017.191

PMCID:: PMC5704193

Abstract Article PDF–3.1M

Select item 553161118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 531622719.

An adaptive variant of TRIB2, rs1057001, is associated with higher expression levels of thermogenic genes in human subcutaneous and visceral adipose tissues

Kazuhiro Nakayama, Sadahiko Iwamoto

J Physiol Anthropol. 2017; 36: 16. Published online 2017 Feb 17. doi: 10.1186/s40101-017-0132-z

PMCID:: PMC5316227

Abstract Article PDF–685K

Select item 526098420.

Yan-Xia Zhang, Yun-Fei Yan, Yue-Mei Liu, You-Jie Li, Han-Han Zhang, Min Pang, Jin-Xia Hu, Wei Zhao, Ning Xie, Ling Zhou, Ping-Yu Wang, Shu-Yang Xie

Cell Death Dis. 2016 Dec; 7(12): e2528. Published online 2016 Dec 22. doi: 10.1038/cddis.2016.432

PMCID:: PMC5260984

Abstract Article PDF–5.7M

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