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Items: 1 to 20 of 295

1.
SERPINE2 promotes liver cancer metastasis by inhibiting c‐Cbl‐mediated EGFR ubiquitination and degradation
Shiyu Zhang, Xing Jia, Haojiang Dai, Xingxin Zhu, Wenfeng Song, Suchen Bian, Hao Wu, Shinuo Chen, Yangbo Tang, Junran Chen, Cheng Jin, Mengqiao Zhou, Haiyang Xie, Shusen Zheng, Penghong Song
Cancer Commun (Lond) 2024 Mar; 44(3): 384–407. Published online 2024 Feb 26. doi: 10.1002/cac2.12527
PMCID:
PMC10958675
AbstractArticlePDF–15M
2.
Cbl and Cbl-b independently regulate EGFR through distinct receptor interaction modes
Itziar Pinilla-Macua, Alexander Sorkin
Mol Biol Cell. 2023 Dec 1; 34(13): ar134. Published online 2023 Nov 21. doi: 10.1091/mbc.E23-02-0058
PMCID:
PMC10848940
AbstractArticlePDF–5.2M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
Age-related loss of chromosome Y is associated with levels of sex hormone binding globulin and clonal hematopoiesis defined by TET2, TP53, and CBL mutations
Ahmed A. Z. Dawoud, William J. Tapper, Nicholas C. P. Cross
Sci Adv. 2023 Apr; 9(16): eade9746. Published online 2023 Apr 21. doi: 10.1126/sciadv.ade9746
PMCID:
PMC10121166
AbstractArticlePDF–1.3M
5.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
6.
Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth
David J. Wisniewski, Mariya S. Liyasova, Soumya Korrapati, Xu Zhang, Shashikala Ratnayake, Qingrong Chen, Samuel F. Gilbert, Alexis Catalano, Donna Voeller, Daoud Meerzaman, Udayan Guha, Natalie Porat-Shliom, Christina M. Annunziata, Stanley Lipkowitz
J Biol Chem. 2023 Jan; 299(1): 102766. Published online 2022 Dec 5. doi: 10.1016/j.jbc.2022.102766
PMCID:
PMC9823131
AbstractArticlePDF–2.5M
7.
CBL通过泛素化降解NCK2抑制乳腺癌细胞的增殖和侵袭
宋 筱羽, 肖 斌, 陆 景润, 张 文武, 李 锦潮, 竹 昕, 孙 朝晖, 李 林海
Nan Fang Yi Ke Da Xue Xue Bao. 2022 Nov 20; 42(11): 1594–1603. Chinese. doi: 10.12122/j.issn.1673-4254.2022.11.02
PMCID:
PMC9742774
AbstractArticlePDF–2.8M
8.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
9.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
10.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
11.
Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy
Di Xiao, Xin Hu, Mei Peng, Jun Deng, Sichun Zhou, Simeng Xu, Jingtao Wu, Xiaoping Yang
Cell Death Dis. 2022 May; 13(5): 499. Published online 2022 May 25. doi: 10.1038/s41419-022-04937-z
PMCID:
PMC9132982
AbstractArticlePDF–6.3M
12.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
13.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
14.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
15.
Licochalcone A Promotes the Ubiquitination of c-Met to Abrogate Gefitinib Resistance
Shuangze Han, Xiaoying Li, Yu Gan, Wei Li
Biomed Res Int. 2022; 2022: 5687832. Published online 2022 Mar 10. doi: 10.1155/2022/5687832
PMCID:
PMC8930240
AbstractArticlePDF–2.4M
16.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
17.
CTEN Inhibits Tumor Angiogenesis and Growth by Targeting VEGFA Through Down-Regulation of β-Catenin in Breast Cancer
Xiangdong Lu, Bin Zhou, Minmin Cao, Qin Shao, Yukai Pan, Tao Zhao
Technol Cancer Res Treat. 2021; 20: 15330338211045506. Published online 2021 Nov 24. doi: 10.1177/15330338211045506
PMCID:
PMC8661028
AbstractArticlePDF–1.9M
18.
G protein pathway suppressor 2 suppresses gastric cancer by destabilizing epidermal growth factor receptor
Yuan Si, Haitao Zhang, Peng Peng, Chu Zhu, Jie Shen, Yilian Xiong, Xuewen Liu, Yuchen Xiang, Wenjuan Li, Yuliang Ren, Fang Wan, Liang Zhang, Ying Liu
Cancer Sci. 2021 Dec; 112(12): 4867–4882. Published online 2021 Oct 20. doi: 10.1111/cas.15151
PMCID:
PMC8645722
AbstractArticlePDF–2.4M
19.
Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL
Manuel Olazábal-Morán, Miriam Sánchez-Ortega, Laura Martínez-Muñoz, Carmen Hernández, Manuel S. Rodríguez, Mario Mellado, Ana C. Carrera
Cells. 2021 Nov; 10(11): 2803. Published online 2021 Oct 20. doi: 10.3390/cells10112803
PMCID:
PMC8616390
AbstractArticlePDF–4.6M
20.
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes
Jalal M. Kazan, Guillaume Desrochers, Claire E. Martin, Hyeonju Jeong, Dmitri Kharitidi, Pirjo M. Apaja, Ariel Roldan, Nicole St. Denis, Anne-Claude Gingras, Gergely L. Lukacs, Arnim Pause
iScience. 2021 Nov 19; 24(11): 103274. Published online 2021 Oct 14. doi: 10.1016/j.isci.2021.103274
PMCID:
PMC8567383
AbstractArticlePDF–5.3M

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