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Items: 1 to 20 of 22

1.
Interaction Between Sex and Organic Anion‐Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib‐N‐Oxide and Regorafenib‐Glucuronide in Mice
Qiang Fu, Mingqing Chen, Jason T. Anderson, Xinxin Sun, Shuiying Hu, Alex Sparreboom, Sharyn D. Baker
Clin Transl Sci. 2019 Jul; 12(4): 400–407. Published online 2019 Apr 6. doi: 10.1111/cts.12630
PMCID:
PMC6662550
ArticlePDF–464K
2.
OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity
Alix F. Leblanc, Jason A. Sprowl, Paola Alberti, Alessia Chiorazzi, W. David Arnold, Alice A. Gibson, Kristen W. Hong, Marissa S. Pioso, Mingqing Chen, Kevin M. Huang, Vamsi Chodisetty, Olivia Costa, Tatiana Florea, Peter de Bruijn, Ron H. Mathijssen, Raquel E. Reinbolt, Maryam B. Lustberg, Lara E. Sucheston-Campbell, Guido Cavaletti, Alex Sparreboom, Shuiying Hu
J Clin Invest. 2018 Feb 1; 128(2): 816–825. Published online 2018 Jan 16. doi: 10.1172/JCI96160
PMCID:
PMC5785270
ArticlePDF–2.2M
3.
Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx
Tristan M. Sissung, Ariel M. Ley, Jonathan D. Strope, Edel M. McCrea, Shaunna Beedie, Cody J. Peer, Suneet Shukla, Jennifer van Velkinburgh, Kelie Reece, Sarah Troutman, Tessa Campbell, Elena Fernandez, Phoebe Huang, Jordan Smith, Nilay Thakkar, David J. Venzon, Stefan Brenner, Wooin Lee, Maria Merino, Ji Luo, Walter Jager, Douglas K. Price, Cindy H. Chau, William D. Figg
Mol Cancer Res. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Mol Cancer Res. 2017 Aug; 15(8): 1096–1105. Published online 2017 Apr 7. doi: 10.1158/1541-7786.MCR-16-0477
PMCID:
PMC5540879
ArticlePDF–801K
4.
Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance
Hannah H. Lee, Brenda F. Leake, Richard B. Kim, Richard H. Ho
Mol Pharmacol. 2017 Jan; 91(1): 14–24. Published online 2017 Jan. doi: 10.1124/mol.116.105544
PMCID:
PMC5198512
ArticlePDF–1.4M
5.
Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2
Yuan-Fu Lu, Jie Liu, Kai Connie Wu, Curtis D. Klaassen
Toxicol Lett. Author manuscript; available in PMC 2016 Apr 1.
Published in final edited form as: Toxicol Lett. 2015 Jan 5; 232(1): 326–332. Published online 2014 Oct 1. doi: 10.1016/j.toxlet.2014.09.027
PMCID:
PMC4382455
ArticlePDF–1.6M
6.
Influence of Drug Formulation on OATP1B-Mediated Transport of Paclitaxel
Annemieke J.M. Nieuweboer, Shuiying Hu, Bruno Hagenbuch, Inge Ghobadi Moghaddam-Helmantel, Alice A. Gibson, Peter de Bruijn, Ron H. J. Mathijssen, Alex Sparreboom
Cancer Res. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Cancer Res. 2014 Jun 1; 74(11): 3137–3145. Published online 2014 Apr 22. doi: 10.1158/0008-5472.CAN-13-3634
PMCID:
PMC4161133
ArticlePDF–1.8M
7.
Synergistic interaction between genetics and disease on pravastatin disposition
John D. Clarke, Rhiannon N. Hardwick, April D. Lake, Andrew J. Lickteig, Michael J. Goedken, Curtis D. Klaassen, Nathan J. Cherrington
J Hepatol. Author manuscript; available in PMC 2015 Jul 1.
Published in final edited form as: J Hepatol. 2014 Jul; 61(1): 139–147. Published online 2014 Mar 5. doi: 10.1016/j.jhep.2014.02.021
PMCID:
PMC4065643
ArticlePDF–1.4M
8.
Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics
Aisha L. Walker, Cynthia S. Lancaster, David Finkelstein, Russell E. Ware, Alex Sparreboom
Am J Physiol Cell Physiol. 2013 Dec 15; 305(12): C1223–C1229. Published online 2013 Aug 28. doi: 10.1152/ajpcell.00232.2013
PMCID:
PMC3882360
Article
9.
Changes in Thyroid Status During Perinatal Development of MCT8-Deficient Male Mice
Alfonso Massimiliano Ferrara, Xiao-Hui Liao, Pilar Gil-Ibáñez, Teresa Marcinkowski, Juan Bernal, Roy E. Weiss, Alexandra M. Dumitrescu, Samuel Refetoff
Endocrinology. 2013 Jul; 154(7): 2533–2541. Published online 2013 May 21. doi: 10.1210/en.2012-2031
PMCID:
PMC3689279
Article
10.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
ArticlePDF–1.1M
11.
Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver
Evita van de Steeg, Viktor Stránecký, Hana Hartmannová, Lenka Nosková, Martin Hřebíček, Els Wagenaar, Anita van Esch, Dirk R. de Waart, Ronald P.J. Oude Elferink, Kathryn E. Kenworthy, Eva Sticová, Mohammad al-Edreesi, A.S. Knisely, Stanislav Kmoch, Milan Jirsa, Alfred H. Schinkel
J Clin Invest. 2012 Feb 1; 122(2): 519–528. Published online 2012 Jan 9. doi: 10.1172/JCI59526
PMCID:
PMC3266790
ArticlePDF–1.1M
12.
Organic Anion–Transporting Polypeptide 1b2 (Oatp1b2) Is Important for the Hepatic Uptake of Unconjugated Bile Acids: Studies in Oatp1b2-Null Mice
Iván L. Csanaky, Hong Lu, Youcai Zhang, Kenichiro Ogura, Supratim Choudhuri, Curtis D. Klaassen
Hepatology. Author manuscript; available in PMC 2011 Oct 4.
Published in final edited form as: Hepatology. 2011 Jan; 53(1): 272–281. Published online 2010 Oct 14. doi: 10.1002/hep.23984
PMCID:
PMC3186067
ArticlePDF–2.8M
13.
Characterization of Organic Anion Transporting Polypeptide 1b2-null Mice: Essential Role in Hepatic Uptake/Toxicity of Phalloidin and Microcystin-LR
Hong Lu, Supratim Choudhuri, Kenichiro Ogura, Iván L. Csanaky, Xiaohong Lei, Xingguo Cheng, Pei-zhen Song, Curtis D. Klaassen
Toxicol Sci. Author manuscript; available in PMC 2011 Sep 27.
Published in final edited form as: Toxicol Sci. 2008 May; 103(1): 35–45. Published online 2008 Feb 21. doi: 10.1093/toxsci/kfn038
PMCID:
PMC3180850
ArticlePDF–1.5M
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
ArticlePDF–1.0M
15.
Organic anion transporting polypeptide 1a/1b–knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs
Evita van de Steeg, Els Wagenaar, Cornelia M.M. van der Kruijssen, Johanna E.C. Burggraaff, Dirk R. de Waart, Ronald P.J. Oude Elferink, Kathryn E. Kenworthy, Alfred H. Schinkel
J Clin Invest. 2010 Aug 2; 120(8): 2942–2952. Published online 2010 Jul 19. doi: 10.1172/JCI42168
PMCID:
PMC2912192
ArticlePDF–839K
16.
Mitochondrial Phosphoproteome Revealed by an Improved IMAC Method and MS/MS/MS
Jaeick Lee, Yingda Xu, Yue Chen, Robert Sprung, Sung Chan Kim, Shanhai Xie, Yingming Zhao
Mol Cell Proteomics. Author manuscript; available in PMC 2010 Jul 13.
Published in final edited form as: Mol Cell Proteomics. 2007 Apr; 6(4): 669–676. Published online 2007 Jan 5. doi: 10.1074/mcp.M600218-MCP200
PMCID:
PMC2902983
ArticlePDF–392K
17.
The European Renal Genome Project: An Integrated Approach Towards Understanding the Genetics of Kidney Development and Disease
TE Willnow, C Antignac, AW Brändli, EI Christensen, RD Cox, D Davidson, JA Davies, O Devuyst, G Eichele, ND Hastie, PJ Verroust, A Schedl, IC Meij
Organogenesis. 2005 Apr-Jun; 2(2): 42–47. doi: 10.4161/org.2.2.2118
PMCID:
PMC2634085
ArticlePDF–629K
18.
Critical Role of PPAR-α in Perfluorooctanoic Acid– and Perfluorodecanoic Acid–Induced Downregulation of Oatp Uptake Transporters in Mouse Livers
Xingguo Cheng, Curtis D. Klaassen
Toxicol Sci. 2008 Nov; 106(1): 37–45. Published online 2008 Aug 14. doi: 10.1093/toxsci/kfn161
PMCID:
PMC2563139
ArticlePDF–317K
19.
Targeted Disruption of Murine Organic Anion-Transporting Polypeptide 1b2 (oatp1b2/Slco1b2) Significantly Alters Disposition of Prototypical Drug Substrates Pravastatin and Rifampin
Hani Zaher, Henriette E. Meyer zu Schwabedissen, Rommel G. Tirona, Melissa L. Cox, Leslie A. Obert, Nidhi Agrawal, Joe Palandra, Jeffrey L. Stock, Richard B. Kim, Joseph A. Ware
Mol Pharmacol. Author manuscript; available in PMC 2009 Aug 1.
Published in final edited form as: Mol Pharmacol. 2008 Aug; 74(2): 320–329. Published online 2008 Apr 15. doi: 10.1124/mol.108.046458
PMCID:
PMC2562886
ArticlePDF–852K
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
ArticlePDF–3.4M

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