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Items: 1 to 20 of 375

1.
Novel insights into RAGE signaling pathways during the progression of amyotrophic lateral sclerosis in RAGE-deficient SOD1 G93A mice
Natalia Nowicka, Kamila Zglejc-Waszak, Judyta Juranek, Agnieszka Korytko, Krzysztof Wąsowicz, Małgorzata Chmielewska-Krzesińska, Joanna Wojtkiewicz
PLoS One. 2024; 19(3): e0299567. Published online 2024 Mar 8. doi: 10.1371/journal.pone.0299567
PMCID:
PMC10923448
AbstractArticlePDF–2.4M
2.
Oxidized SOD1 accelerates cellular senescence in neural stem cells
Teng Guan, Ying Guo, Ting Zhou, Qiang Yu, Jingyi Sun, Baoliang Sun, Guohui Zhang, Jiming Kong
Stem Cell Res Ther. 2024; 15: 55. Published online 2024 Feb 27. doi: 10.1186/s13287-024-03669-5
PMCID:
PMC10900543
AbstractArticlePDF–4.6M
3.
Spinal cord abnormal autophagy and mitochondria energy metabolism are modified by swim training in SOD1-G93A mice
Katarzyna Patrycja Dzik, Damian Józef Flis, Katarzyna Barbara Kaczor-Keller, Zofia Kinga Bytowska, Mateusz Jakub Karnia, Wiesław Ziółkowski, Jan Jacek Kaczor
J Mol Med (Berl) 2024; 102(3): 379–390. Published online 2024 Jan 10. doi: 10.1007/s00109-023-02410-8
PMCID:
PMC10879285
AbstractArticlePDF–3.8M
4.
Leptin haploinsufficiency exerts sex-dependent partial protection in SOD1G93A mice by reducing inflammatory pathways in the adipose tissue
Luis C. Fernández-Beltrán, Zeinab Ali, Angélica Larrad-Sanz, Juan I. Lopez-Carbonero, Juan M. Godoy-Corchuelo, Irene Jimenez-Coca, Irene Garcia-Toledo, Liz Bentley, Ulises Gomez-Pinedo, Jordi A. Matias-Guiu, Maria Jose Gil-Moreno, Jorge Matias-Guiu, Silvia Corrochano
Sci Rep. 2024; 14: 2671. Published online 2024 Feb 1. doi: 10.1038/s41598-024-52439-z
PMCID:
PMC10834470
AbstractArticlePDF–5.7M
5.
Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS
Md Amin Hossain, Richa Sarin, Daniel P. Donnelly, Brandon C. Miller, Alexandra Weiss, Luke McAlary, Svetlana V. Antonyuk, Joseph P. Salisbury, Jakal Amin, Jeremy B. Conway, Samantha S. Watson, Jenifer N. Winters, Yu Xu, Novera Alam, Rutali R. Brahme, Haneyeh Shahbazian, Durgalakshmi Sivasankar, Swathi Padmakumar, Aziza Sattarova, Aparna C. Ponmudiyan, Tanvi Gawde, David E. Verrill, Wensheng Yang, Sunanda Kannapadi, Leigh D. Plant, Jared R. Auclair, Lee Makowski, Gregory A. Petsko, Dagmar Ringe, Nathalie Y. R. Agar, David J. Greenblatt, Mary Jo Ondrechen, Yunqiu Chen, Justin J. Yerbury, Roman Manetsch, S. Samar Hasnain, Robert H. Brown, Jr., Jeffrey N. Agar
PLoS Biol. 2024 Jan; 22(1): e3002462. Published online 2024 Jan 30. doi: 10.1371/journal.pbio.3002462
PMCID:
PMC10826971
AbstractArticlePDF–5.0M
6.
miR-195b is required for proper cellular homeostasis in the elderly
Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco
Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8
PMCID:
PMC10774362
AbstractArticlePDF–3.7M
7.
ALS-linked SOD1 mutations impair mitochondrial-derived vesicle formation and accelerate aging
Ying Guo, Teng Guan, Qiang Yu, Nitesh Sanghai, Kashfia Shafiq, Meiyu Li, Xin Jiao, Donghui Na, Guohui Zhang, Jiming Kong
Redox Biol. 2024 Feb; 69: 102972. Published online 2023 Nov 24. doi: 10.1016/j.redox.2023.102972
PMCID:
PMC10746562
AbstractArticlePDF–11M
8.
Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice
Abhirami K. Iyer, Kathleen M. Schoch, Anthony Verbeck, Grant Galasso, Hao Chen, Sarah Smith, Anna Oldenborg, Timothy M. Miller, Celeste M. Karch, Azad Bonni
PLoS One. 2023; 18(11): e0294731. Published online 2023 Nov 28. doi: 10.1371/journal.pone.0294731
PMCID:
PMC10683999
AbstractArticlePDF–3.0M
9.
The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model
Hui Zhao, Ronald J. Wong, David K. Stevenson
PLoS One. 2023; 18(11): e0294185. Published online 2023 Nov 10. doi: 10.1371/journal.pone.0294185
PMCID:
PMC10637699
AbstractArticlePDF–3.6M
10.
Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice
Jacob I. Ayers, Guilian Xu, Qing Lu, Kristy Dillon, Susan Fromholt, David R. Borchelt
Viruses. 2023 Sep; 15(9): 1819. Published online 2023 Aug 26. doi: 10.3390/v15091819
PMCID:
PMC10534885
AbstractArticlePDF–4.8M
11.
CXCR2 Is Deregulated in ALS Spinal Cord and Its Activation Triggers Apoptosis in Motor Neuron-Like Cells Overexpressing hSOD1-G93A
Valentina La Cognata, Agata Grazia D’Amico, Grazia Maugeri, Giovanna Morello, Maria Guarnaccia, Benedetta Magrì, Eleonora Aronica, Velia D’Agata, Sebastiano Cavallaro
Cells. 2023 Jul; 12(14): 1813. Published online 2023 Jul 9. doi: 10.3390/cells12141813
PMCID:
PMC10377984
AbstractArticlePDF–7.7M
12.
Cortical glia in SOD1(G93A) mice are subtly affected by ALS-like pathology
Tereza Filipi, Zuzana Matusova, Pavel Abaffy, Ondrej Vanatko, Jana Tureckova, Sarka Benesova, Monika Kubiskova, Denisa Kirdajova, Jakub Zahumensky, Lukas Valihrach, Miroslava Anderova
Sci Rep. 2023; 13: 6538. Published online 2023 Apr 21. doi: 10.1038/s41598-023-33608-y
PMCID:
PMC10121704
AbstractArticlePDF–2.5M
13.
Activating mitofusins interrupts mitochondrial degeneration and delays disease progression in SOD1 mutant amyotrophic lateral sclerosis
Xiawei Dang, Lihong Zhang, Antonietta Franco, Gerald W Dorn II
Hum Mol Genet. 2023 Apr 1; 32(7): 1208–1222. Published online 2022 Nov 23. doi: 10.1093/hmg/ddac287
PMCID:
PMC10026224
AbstractArticlePDF–2.3M
14.
Extracellular-superoxide dismutase DNA methylation promotes oxidative stress in homocysteine-induced atherosclerosis: EC-SOD DNA methylation regulates atherosclerosis in ApoE–/– mice
Shengchao Ma, Guanjun Lu, Qing Zhang, Ning Ding, Yuzhen Jie, Hui Zhang, Lingbo Xu, Lin Xie, Xiaoling Yang, Huiping Zhang, Yideng Jiang
Acta Biochim Biophys Sin (Shanghai) 2022 Sep; 54(9): 1222–1233. Published online 2022 Jul 22. doi: 10.3724/abbs.2022093
PMCID:
PMC9827811
AbstractArticlePDF–5.2M
15.
Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1G93A mouse model of amyotrophic lateral sclerosis
Sara Salvany, Anna Casanovas, Lídia Piedrafita, Sílvia Gras, Jordi Calderó, Josep E. Esquerda
Brain Pathol. 2022 Nov; 32(6): e13078. Published online 2022 May 18. doi: 10.1111/bpa.13078
PMCID:
PMC9616096
AbstractArticlePDF–37M
16.
Impact of aging and oxidative stress on specific components of excitation contraction coupling in regulating force generation
Hongyang Xu, Bumsoo Ahn, Holly Van Remmen
Sci Adv. 2022 Oct; 8(43): eadd7377. Published online 2022 Oct 26. doi: 10.1126/sciadv.add7377
PMCID:
PMC9604602
AbstractArticlePDF–5.3M
17.
ROS-Mediated Enamel Formation Disturbance Characterized by Alternative Cervical Loop Cell Proliferation and Downregulation of RhoA/ROCK in Ameloblasts
Yuchan Xu, Yunyan Zhang, Jingwen Zheng, Mingxue Xu, Yuzhi Yang, Weihua Guo
Oxid Med Cell Longev. 2022; 2022: 5769679. Published online 2022 Oct 17. doi: 10.1155/2022/5769679
PMCID:
PMC9592207
AbstractArticlePDF–4.7M
18.
Non-enzymatic role of SOD1 in intestinal stem cell growth
Ying-Chao Wang, Xiao-Xu Leng, Cheng-Bei Zhou, Shi-Yuan Lu, Chi Kwan Tsang, Jie Xu, Ming-Ming Zhang, Hui-Min Chen, Jing-Yuan Fang
Cell Death Dis. 2022 Oct; 13(10): 882. Published online 2022 Oct 20. doi: 10.1038/s41419-022-05267-w
PMCID:
PMC9585064
AbstractArticlePDF–5.0M
19.
Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma
Nidheesh Thadathil, Ramasamy Selvarani, Sabira Mohammed, Evan H. Nicklas, Albert L. Tran, Maria Kamal, Wenyi Luo, Jacob L. Brown, Marcus M. Lawrence, Agnieszka K. Borowik, Benjamin F. Miller, Holly Van Remmen, Arlan Richardson, Sathyaseelan S. Deepa
Aging Cell. 2022 Aug; 21(8): e13676. Published online 2022 Jul 23. doi: 10.1111/acel.13676
PMCID:
PMC9381894
AbstractArticlePDF–2.6M
20.
Astrocyte‐targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast‐fatigable motor units in a mouse model of amyotrophic lateral sclerosis
Cylia Rochat, Nathalie Bernard‐Marissal, Emma Källstig, Sylvain Pradervand, Florence E. Perrin, Patrick Aebischer, Cédric Raoul, Bernard L. Schneider
Glia. 2022 May; 70(5): 842–857. Published online 2022 Jan 3. doi: 10.1002/glia.24140
PMCID:
PMC9303637
AbstractArticlePDF–4.1M

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