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Items: 1 to 20 of 191

1.
TANGO6 regulates cell proliferation via COPI vesicle-mediated RPB2 nuclear entry
Zhi Feng, Shengnan Liu, Ming Su, Chunyu Song, Chenyu Lin, Fangying Zhao, Yang Li, Xianyan Zeng, Yong Zhu, Yu Hou, Chunguang Ren, Huan Zhang, Ping Yi, Yong Ji, Chao Wang, Hongtao Li, Ming Ma, Lingfei Luo, Li Li
Nat Commun. 2024; 15: 2371. Published online 2024 Mar 15. doi: 10.1038/s41467-024-46720-y
PMCID:
PMC10943085
AbstractArticlePDF–6.1M
2.
NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells
Hye Yeon Choi, Yicheng Zhu, Xuyao Zhao, Simran Mehta, Juan Carlos Hernandez, Jae-Jin Lee, Yi Kou, Risa Machida, Mauro Giacca, Giannino Del Sal, Ratna Ray, Hyungjin Eoh, Stanley M. Tahara, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
Exp Mol Med. 2024 Feb; 56(2): 461–477. Published online 2024 Feb 27. doi: 10.1038/s12276-024-01174-6
PMCID:
PMC10907578
AbstractArticlePDF–9.7M
3.
HNF4A guides the MLL4 complex to establish and maintain H3K4me1 at gene regulatory elements
Avinash Thakur, Kwangjin Park, Rebecca Cullum, Bettina M. Fuglerud, Mina Khoshnoodi, Sibyl Drissler, Tabea L. Stephan, Jeremy Lotto, Donghwan Kim, Frank J. Gonzalez, Pamela A. Hoodless
Commun Biol. 2024; 7: 144. Published online 2024 Jan 31. doi: 10.1038/s42003-024-05835-0
PMCID:
PMC10830483
AbstractArticlePDF–13M
4.
Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis
Yadong Fu, Xiaoxi Zhou, Lin Wang, Weiguo Fan, Siqi Gao, Danyan Zhang, Zhiyang Ling, Yaguang Zhang, Liyan Ma, Fang Bai, Jiamei Chen, Bing Sun, Ping Liu
Redox Biol. 2024 Feb; 69: 103029. Published online 2024 Jan 3. doi: 10.1016/j.redox.2024.103029
PMCID:
PMC10808927
AbstractArticlePDF–18M
5.
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function
Yue Zhu, Qinqin Wang, Xinyu Xie, Cuihong Ma, Yuemei Qiao, Yu Zhang, Yanjun Wu, Yuan Gao, Jing Jiang, Xin Liu, Jianfeng Chen, Chen Li, Gaoxiang Ge
Cell Death Dis. 2024 Jan; 15(1): 55. Published online 2024 Jan 15. doi: 10.1038/s41419-024-06441-y
PMCID:
PMC10789742
AbstractArticlePDF–8.7M
6.
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling
Andrew S. Mendiola, Zhaoqi Yan, Karuna Dixit, Jeffrey R. Johnson, Mehdi Bouhaddou, Anke Meyer-Franke, Min-Gyoung Shin, Yu Yong, Ayushi Agrawal, Eilidh MacDonald, Gayathri Muthukumar, Clairice Pearce, Nikhita Arun, Belinda Cabriga, Rosa Meza-Acevedo, Maria del Pilar S. Alzamora, Scott S. Zamvil, Alexander R. Pico, Jae Kyu Ryu, Nevan J. Krogan, Katerina Akassoglou
Nat Immunol. 2023; 24(7): 1173–1187. Published online 2023 Jun 8. doi: 10.1038/s41590-023-01522-0
PMCID:
PMC10307624
AbstractArticlePDF–18M
7.
The circadian demethylation of a unique intronic deoxymethylCpG-rich island boosts the transcription of its cognate circadian clock output gene
Nisha Misra, Manohar Damara, Tao Ye, Pierre Chambon
Proc Natl Acad Sci U S A. 2023 Feb 21; 120(8): e2214062120. Published online 2023 Feb 15. doi: 10.1073/pnas.2214062120
PMCID:
PMC9974474
AbstractArticlePDF–1.1M
8.
A conditional Smg6 mutant mouse model reveals circadian clock regulation through the nonsense-mediated mRNA decay pathway
Georgia Katsioudi, René Dreos, Enes S. Arpa, Sevasti Gaspari, Angelica Liechti, Miho Sato, Christian H. Gabriel, Achim Kramer, Steven A. Brown, David Gatfield
Sci Adv. 2023 Jan; 9(2): eade2828. Published online 2023 Jan 13. doi: 10.1126/sciadv.ade2828
PMCID:
PMC9839329
AbstractArticlePDF–2.3M
9.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
10.
Oncogenic β-catenin stimulation of AKT2–CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer
Fangming Liu, Xiaochen Gai, Yuting Wu, Baohui Zhang, Xiaoyu Wu, Rongrong Cheng, Bufu Tang, Kezhuo Shang, Na Zhao, Weiwei Deng, Jie Chen, Zhengyi Zhang, Song Gu, Liang Zheng, Hongbing Zhang
Proc Natl Acad Sci U S A. 2022 Sep 27; 119(39): e2202157119. Published online 2022 Sep 19. doi: 10.1073/pnas.2202157119
PMCID:
PMC9522414
AbstractArticlePDF–2.8M
11.
A non-canonical vitamin K cycle is a potent ferroptosis suppressor
Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, Adam Wahida, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer, Maceler Aldrovandi, Bernhard Henkelmann, Ken-ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, Regina Feederle, Daniela Hass, Adriano Maida, André Santos Dias Mourão, Andreas Linkermann, Edward K. Geissler, Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, Derek A. Pratt, Marcus Conrad
Nature. 2022; 608(7924): 778–783. Published online 2022 Aug 3. doi: 10.1038/s41586-022-05022-3
PMCID:
PMC9402432
AbstractArticlePDF–9.5M
12.
HNF4A modulates glucocorticoid action in the liver
A. Louise Hunter, Toryn M. Poolman, Donghwan Kim, Frank J. Gonzalez, David A. Bechtold, Andrew S.I. Loudon, Mudassar Iqbal, David W. Ray
Cell Rep. 2022 Apr 19; 39(3): 110697. Published online 2022 Apr 19. doi: 10.1016/j.celrep.2022.110697
PMCID:
PMC9380254
AbstractArticle
13.
Coordinated Cross-Talk Between the Myc and Mlx Networks in Liver Regeneration and Neoplasia
Huabo Wang, Jie Lu, Frances Alencastro, Alexander Roberts, Julia Fiedor, Patrick Carroll, Robert N. Eisenman, Sarangarajan Ranganathan, Michael Torbenson, Andrew W. Duncan, Edward V. Prochownik
Cell Mol Gastroenterol Hepatol. 2022; 13(6): 1785–1804. Published online 2022 Mar 5. doi: 10.1016/j.jcmgh.2022.02.018
PMCID:
PMC9046243
AbstractArticlePDF–3.8M
14.
Redundant Functions of ERK1 and ERK2 Maintain Mouse Liver Homeostasis Through Down‐Regulation of Bile Acid Synthesis
Francesca Cingolani, Yunshan Liu, Yang Shen, Jing Wen, Alton B. Farris, Mark J. Czaja
Hepatol Commun. 2022 May; 6(5): 980–994. Published online 2021 Dec 22. doi: 10.1002/hep4.1867
PMCID:
PMC9035584
AbstractArticlePDF–2.1M
15.
Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation
Sophia Pantasis, Juliane Friemel, Salome Mirjam Brütsch, Zehan Hu, Sabrina Krautbauer, Gerhard Liebisch, Joern Dengjel, Achim Weber, Sabine Werner, Mattia Renato Bordoli
J Cell Sci. 2022 Apr 1; 135(7): jcs259243. Published online 2022 Apr 12. doi: 10.1242/jcs.259243
PMCID:
PMC9016620
AbstractArticle
16.
Asymptomatic Hyperuricemia Promotes Recovery from Ischemic Organ Injury by Modulating the Phenotype of Macrophages
Viviane Gnemmi, Qiubo Li, Qiuyue Ma, Letizia De Chiara, Giulia Carangelo, Chenyu Li, Mireia Molina-Van den Bosch, Paola Romagnani, Hans-Joachim Anders, Stefanie Steiger
Cells. 2022 Feb; 11(4): 626. Published online 2022 Feb 11. doi: 10.3390/cells11040626
PMCID:
PMC8869798
AbstractArticlePDF–3.7M
17.
CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing
Han Zeng, Hong Qin, Meng Liao, Enze Zheng, Xiaoqing Luo, Anhua Xiao, Yiyu Li, Lin Chen, Li Wei, Lei Zhao, Xiong Z. Ruan, Ping Yang, Yaxi Chen
Mol Metab. 2022 Mar; 57: 101428. Published online 2021 Dec 30. doi: 10.1016/j.molmet.2021.101428
PMCID:
PMC8810570
AbstractArticlePDF–4.7M
18.
Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma
Wei Cheng, Hao-Long Li, Shao-Yan Xi, Xiao-Feng Zhang, Yun Zhu, Le Xing, Yan-Xuan Mo, Mei-Mei Li, Fan-En Kong, Wen-Jie Zhu, Xiao-Gang Chen, Hui-Qing Cui, Zhi-Ming Cao, Yuan-Feng Gong, Yun-Qiang Tang, Yan Zhang, Xin-Yuan Guan, Ning-Fang Ma, Ming Liu
Nat Commun. 2021; 12: 7142. Published online 2021 Dec 8. doi: 10.1038/s41467-021-27525-9
PMCID:
PMC8654996
AbstractArticlePDF–12M
19.
Hepatic mitochondrial SAB deletion or knockdown alleviates diet induced metabolic syndrome, steatohepatitis and hepatic fibrosis
Sanda Win, Robert W.M. Min, Jun Zhang, Gary Kanel, Brad Wanken, Yibu Chen, Meng Li, Ying Wang, Ayako Suzuki, Filbert W.M. Aung, Susan F. Murray, Mariam Aghajan, Tin A. Than, Neil Kaplowitz
Hepatology. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: Hepatology. 2021 Dec; 74(6): 3127–3145. Published online 2021 Oct 10. doi: 10.1002/hep.32083
PMCID:
PMC8639630
AbstractArticlePDF–2.9M
20.
Podoplanin is dispensable for mineralized tissue formation and maintenance in the Swiss outbred mouse background.
Masako Toda Nakamura, Honghao Zhang, Dayong Guo, Hiroki Ueharu, Haichun Pan, Greg Scott, Marie Harris, Manas Ray, Jiang Q. Feng, Stephen E. Harris, Lynda F. Bonewald, Yuji Mishina
Genesis. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: Genesis. 2021 Oct; 59(10): e23450. Published online 2021 Sep 6. doi: 10.1002/dvg.23450
PMCID:
PMC8526399
AbstractArticlePDF–1.3M

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