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Items: 1 to 20 of 83

1.
Mutagenesis and structural studies reveal the basis for the specific binding of SARS-CoV-2 SL3 RNA element with human TIA1 protein
Dong Zhang, Lulu Qiao, Xiaobo Lei, Xiaojing Dong, Yunguang Tong, Jianwei Wang, Zhiye Wang, Ruhong Zhou
Nat Commun. 2023; 14: 3715. Published online 2023 Jun 22. doi: 10.1038/s41467-023-39410-8
PMCID:
PMC10287707
AbstractArticlePDF–2.1M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures
Naotaka Sekiyama, Kiyofumi Takaba, Saori Maki-Yonekura, Ken-ichi Akagi, Yasuko Ohtani, Kayo Imamura, Tsuyoshi Terakawa, Keitaro Yamashita, Daigo Inaoka, Koji Yonekura, Takashi S. Kodama, Hidehito Tochio
Proc Natl Acad Sci U S A. 2022 Sep 20; 119(38): e2122523119. Published online 2022 Sep 16. doi: 10.1073/pnas.2122523119
PMCID:
PMC9499527
AbstractArticlePDF–2.5M
4.
Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer
Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz
Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7
PMCID:
PMC9290241
AbstractArticlePDF–8.2M
5.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
6.
Intracellular accumulation of tau inhibits autophagosome formation by activating TIA1-amino acid-mTORC1 signaling
Meng-Zhu Li, En-Jie Liu, Qiu-Zhi Zhou, Shi-Hong Li, Shi-Jie Liu, Hai-Tao Yu, Qi-Hang Pan, Fei Sun, Ting He, Wei-Jin Wang, Dan Ke, Yu-Qi Feng, Jun Li, Jian-Zhi Wang
Mil Med Res. 2022; 9: 38. Published online 2022 Jul 7. doi: 10.1186/s40779-022-00396-x
PMCID:
PMC9264508
AbstractArticlePDF–7.2M
7.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
8.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
9.
The Multifunctional Faces of T-Cell Intracellular Antigen 1 in Health and Disease
Andrea Fernández-Gómez, José M. Izquierdo
Int J Mol Sci. 2022 Feb; 23(3): 1400. Published online 2022 Jan 26. doi: 10.3390/ijms23031400
PMCID:
PMC8836218
AbstractArticlePDF–3.3M
10.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing
Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6
PMCID:
PMC8748958
AbstractArticlePDF–3.0M
11.
Amyotrophic lateral sclerosis (ALS) linked mutation in Ubiquilin 2 affects stress granule assembly via TIA‐1
Guangnan Peng, Ao Gu, Hongyan Niu, Linlin Chen, Yan Chen, Miaojin Zhou, Yiti Zhang, Jie Liu, Licong Cai, Desheng Liang, Xionghao Liu, Mujun Liu
CNS Neurosci Ther. 2022 Jan; 28(1): 105–115. Published online 2021 Nov 8. doi: 10.1111/cns.13757
PMCID:
PMC8673703
AbstractArticlePDF–2.1M
12.
Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53
Yafei Guo, Qin Li, Gang Zhao, Jie Zhang, Hang Yuan, Tianyu Feng, Deqiong Ou, Rui Gu, Siqi Li, Kai Li, Ping Lin
Cell Death Dis. 2021 Oct; 12(10): 945. Published online 2021 Oct 14. doi: 10.1038/s41419-021-04208-3
PMCID:
PMC8516922
AbstractArticlePDF–8.2M
13.
Identification of TIA1 mRNA targets during human neuronal development
Loryn P. Byres, Marat Mufteev, Kyoko E. Yuki, Wei Wei, Alina Piekna, Michael D. Wilson, Deivid C. Rodrigues, James Ellis
Mol Biol Rep. 2021; 48(9): 6349–6361. Published online 2021 Aug 19. doi: 10.1007/s11033-021-06634-0
PMCID:
PMC8437838
AbstractArticlePDF–5.1M
14.
Tandem RNA binding sites induce self-association of the stress granule marker protein TIA-1
Fionna E Loughlin, Danella L West, Menachem J Gunzburg, Saboora Waris, Simon A Crawford, Matthew C J Wilce, Jacqueline A Wilce
Nucleic Acids Res. 2021 Mar 18; 49(5): 2403–2417. Published online 2021 Feb 24. doi: 10.1093/nar/gkab080
PMCID:
PMC7969032
AbstractArticlePDF–3.9M
15.
Global proteomics of Ubqln2-based murine models of ALS
Alexandra M. Whiteley, Miguel A. Prado, Stefanie A.H. de Poot, Joao A. Paulo, Marissa Ashton, Sara Dominguez, Martin Weber, Hai Ngu, John Szpyt, Mark P. Jedrychowski, Amy Easton, Steven P. Gygi, Thimo Kurz, Mervyn J. Monteiro, Eric J. Brown, Daniel Finley
J Biol Chem. 2021 Jan-Jun; 296: 100153. Published online 2020 Dec 10. doi: 10.1074/jbc.RA120.015960
PMCID:
PMC7873701
AbstractArticlePDF–3.0M
16.
AMPK, a key regulator of metabolism and autophagy, is activated by lysosomal damage via a novel galectin-directed ubiquitin signal transduction system
Jingyue Jia, Bhawana Bissa, Lukas Brecht, Lee Allers, Seong Won Choi, Yuexi Gu, Mark Zbinden, Mark R. Burge, Graham Timmins, Kenneth Hallows, Christian Behrends, Vojo Deretic
Mol Cell. Author manuscript; available in PMC 2021 Mar 5.
Published in final edited form as: Mol Cell. 2020 Mar 5; 77(5): 951–969.e9. Published online 2020 Jan 28. doi: 10.1016/j.molcel.2019.12.028
PMCID:
PMC7785494
AbstractArticlePDF–2.9M
17.
BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A
Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng
Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676
PMCID:
PMC7606008
AbstractArticlePDF–2.5M
18.
ARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection
Ruth Hüttenhain, Jiewei Xu, Lily A. Burton, David E. Gordon, Judd F. Hultquist, Jeffrey R. Johnson, Laura Satkamp, Joseph Hiatt, David Y. Rhee, Kheewoong Baek, David C. Crosby, Alan D. Frankel, Alexander Marson, J. Wade Harper, Arno F. Alpi, Brenda A. Schulman, John D. Gross, Nevan J. Krogan
Cell Host Microbe. Author manuscript; available in PMC 2020 Jul 10.
Published in final edited form as: Cell Host Microbe. 2019 Jul 10; 26(1): 86–99.e7. Published online 2019 Jun 25. doi: 10.1016/j.chom.2019.05.008
PMCID:
PMC7153695
AbstractArticlePDF–2.6M
19.
Typical Stress Granule Proteins Interact with the 3′ Untranslated Region of Enterovirus D68 To Inhibit Viral Replication
Jinyan Cheng, Shuai Gao, Cheng Zhu, Sihua Liu, Jinyu Li, Jun Kang, Zhiyun Wang, Tao Wang
J Virol. 2020 Apr; 94(7): e02041-19. Prepublished online 2020 Jan 15. Published online 2020 Mar 17. doi: 10.1128/JVI.02041-19
PMCID:
PMC7081905
AbstractArticlePDF–4.4M
20.
Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC
Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong
eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223
PMCID:
PMC6927754
AbstractArticlePDF–5.1M

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