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Items: 1 to 20 of 43

1.
LKB1‐SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition
Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon‐Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan‐Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub
EMBO Mol Med. 2023 Dec; 15(12): e17719. Published online 2023 Nov 15. doi: 10.15252/emmm.202317719
PMCID:
PMC10701601
ArticlePDF–3.7M
2.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
ArticlePDF–4.2M
3.
SIK2 promotes ovarian cancer cell motility and metastasis by phosphorylating MYLK
Xiu Shi, Xuejiao Yu, Juan Wang, Shimin Bian, Qiutong Li, Fengqing Fu, Xinwei Zou, Lin Zhang, Robert C. Bast, Jr., Zhen Lu, Lingchuan Guo, Youguo Chen, Jinhua Zhou
Mol Oncol. 2022 Jul; 16(13): 2558–2574. Published online 2022 Mar 25. doi: 10.1002/1878-0261.13208
PMCID:
PMC9251837
ArticlePDF–12M
4.
SIK2 kinase synthetic lethality is driven by spindle assembly defects in FANCA‐deficient cells
Ka‐Kui Chan, Zahi Abdul‐Sater, Aditya Sheth, Dana K. Mitchell, Richa Sharma, Donna M. Edwards, Ying He, Grzegorz Nalepa, Steven D. Rhodes, D. Wade Clapp, Elizabeth A. Sierra Potchanant
Mol Oncol. 2022 Feb; 16(4): 860–884. Published online 2021 Jun 28. doi: 10.1002/1878-0261.13027
PMCID:
PMC8847993
ArticlePDF–5.3M
5.
Role of salt-inducible kinase 2 in the malignant behavior and glycolysis of colorectal cancer cells
Xiaohong Ni, Yongjiang Feng, Xiangwei Fu
Mol Med Rep. 2021 Nov; 24(5): 822. Published online 2021 Sep 24. doi: 10.3892/mmr.2021.12460
PMCID:
PMC8485122
ArticlePDF–6.6M
6.
Silencing the G-protein coupled receptor 3-salt inducible kinase 2 pathway promotes human β cell proliferation
Caterina Iorio, Jillian L. Rourke, Lisa Wells, Jun-Ichi Sakamaki, Emily Moon, Queenie Hu, Tatsuya Kin, Robert A. Screaton
Commun Biol. 2021; 4: 907. Published online 2021 Jul 23. doi: 10.1038/s42003-021-02433-2
PMCID:
PMC8302759
ArticlePDF–3.4M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
ArticlePDF–2.2M
8.
SIK2 orchestrates actin-dependent host response upon Salmonella infection
Marcel Hahn, Adriana Covarrubias-Pinto, Lina Herhaus, Shankha Satpathy, Kevin Klann, Keith B. Boyle, Christian Münch, Krishnaraj Rajalingam, Felix Randow, Chunaram Choudhary, Ivan Dikic
Proc Natl Acad Sci U S A. 2021 May 11; 118(19): e2024144118. Published online 2021 May 4. doi: 10.1073/pnas.2024144118
PMCID:
PMC8126862
ArticlePDF–3.0M
9.
SIK2 represses AKT/GSK3β/β‐catenin signaling and suppresses gastric cancer by inhibiting autophagic degradation of protein phosphatases
Xiao‐man Dai, Yan‐hui Zhang, Xiao‐han Lin, Xiao‐xing Huang, Yi Zhang, Chao‐rong Xue, Wan‐nan Chen, Jian‐xin Ye, Xin‐jian Lin, Xu Lin
Mol Oncol. 2021 Jan; 15(1): 228–245. Published online 2020 Nov 20. doi: 10.1002/1878-0261.12838
PMCID:
PMC7782074
ArticlePDF–5.2M
10.
Salt-inducible Kinases Are Critical Determinants of Female Fertility
Marah Armouti, Nicola Winston, Osamu Hatano, Elie Hobeika, Jennifer Hirshfeld-Cytron, Juergen Liebermann, Hiroshi Takemori, Carlos Stocco
Endocrinology. 2020 Jul; 161(7): bqaa069. Published online 2020 Apr 28. doi: 10.1210/endocr/bqaa069
PMCID:
PMC7286620
Article
11.
Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses
Luke D. Hutchinson, Nicola J. Darling, Stephanos Nicolaou, Ilaria Gori, Daniel R. Squair, Philip Cohen, Caroline S. Hill, Gopal P. Sapkota
Cell Death Dis. 2020 Jan; 11(1): 49. Published online 2020 Jan 22. doi: 10.1038/s41419-020-2241-6
PMCID:
PMC6976658
ArticlePDF–2.7M
12.
SIK2 enhances synthesis of fatty acid and cholesterol in ovarian cancer cells and tumor growth through PI3K/Akt signaling pathway
Jing Zhao, Xiaohong Zhang, Tian Gao, Shanci Wang, Yiran Hou, Peng Yuan, Yi Yang, Tao Yang, Jinliang Xing, Jibin Li, Shujuan Liu
Cell Death Dis. 2020 Jan; 11(1): 25. Published online 2020 Jan 13. doi: 10.1038/s41419-019-2221-x
PMCID:
PMC6957524
ArticlePDF–3.0M
13.
Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development
Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong
J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107
PMCID:
PMC6763242
ArticlePDF–12M
14.
Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes
Johanna Säll, Annie M. L. Pettersson, Christel Björk, Emma Henriksson, Sebastian Wasserstrom, Wilhelm Linder, Yuedan Zhou, Ola Hansson, Daniel P. Andersson, Mikael Ekelund, Eva Degerman, Karin G. Stenkula, Jurga Laurencikiene, Olga Göransson
Diabetologia. 2017; 60(2): 314–323. Published online 2016 Nov 2. doi: 10.1007/s00125-016-4141-y
PMCID:
PMC6518086
ArticlePDF–631K
15.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
ArticlePDF–2.3M
16.
14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs)
Tim Sonntag, Joan M. Vaughan, Marc Montminy
FEBS J. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: FEBS J. 2018 Feb; 285(3): 467–480. Published online 2018 Jan 9. doi: 10.1111/febs.14351
PMCID:
PMC5799007
ArticlePDF–2.3M
17.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
ArticlePDF–3.2M
18.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
ArticlePDF–2.7M
19.
SIK2 Restricts Autophagic Flux To Support Triple-Negative Breast Cancer Survival
Kimberly E. Maxfield, Jennifer Macion, Hariprasad Vankayalapati, Angelique W. Whitehurst
Mol Cell Biol. 2016 Dec 15; 36(24): 3048–3057. Prepublished online 2016 Oct 3. Published online 2016 Nov 28. doi: 10.1128/MCB.00380-16
PMCID:
PMC5126292
ArticlePDF–1.1M
20.
SIKs control osteocyte responses to parathyroid hormone
Marc N. Wein, Yanke Liang, Olga Goransson, Thomas B. Sundberg, Jinhua Wang, Elizabeth A. Williams, Maureen J. O'Meara, Nicolas Govea, Belinda Beqo, Shigeki Nishimori, Kenichi Nagano, Daniel J. Brooks, Janaina S. Martins, Braden Corbin, Anthony Anselmo, Ruslan Sadreyev, Joy Y. Wu, Kei Sakamoto, Marc Foretz, Ramnik J. Xavier, Roland Baron, Mary L. Bouxsein, Thomas J. Gardella, Paola Divieti-Pajevic, Nathanael S. Gray, Henry M. Kronenberg
Nat Commun. 2016; 7: 13176. Published online 2016 Oct 19. doi: 10.1038/ncomms13176
Correction in:
Nat Commun. 2017; 8: 14745.
PMCID:
PMC5075806
ArticlePDF–2.4M

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