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Select item 105892971.

Hnrnpk is essential for embryonic limb bud development as a transcription activator and a collaborator of insulator protein Ctcf

Yuyu Chen, Taifeng Zhou, Zhiheng Liao, Wenjie Gao, Jinna Wu, Shun Zhang, Yongyong Li, Hengyu Liu, Hang Zhou, Caixia Xu, Peiqiang Su

Cell Death Differ. 2023 Oct; 30(10): 2293–2308. Published online 2023 Aug 22. doi: 10.1038/s41418-023-01207-z

PMCID:: PMC10589297

Abstract Article PDF–16M

Select item 99816222.

Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant

Kwang Wook Min, Namsuk Kim, Jae Hoon Lee, Younghoon Sung, Museong Kim, Eun Jung Lee, Jong-Myeong Kim, Jae-Hyun Kim, Jaeyoung Lee, Wonjin Cho, Jee Myung Yang, Nury Kim, Jaehoon Kim, C. Justin Lee, Young-Gyun Park, Seung-Hee Lee, Han-Woong Lee, Jin Woo Kim

Exp Mol Med. 2023 Feb; 55(2): 385–400. Published online 2023 Feb 3. doi: 10.1038/s12276-023-00930-4

PMCID:: PMC9981622

Abstract Article PDF–7.4M

Select item 94407563.

TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells

Jessica W. Bertol, Shelby Johnston, Rabia Ahmed, Victoria K. Xie, Kelsea M. Hubka, Lissette Cruz, Larissa Nitschke, Marta Stetsiv, Jeremy P. Goering, Paul Nistor, Sally Lowell, Hanne Hoskens, Peter Claes, Seth M. Weinberg, Irfan Saadi, Mary C. Farach-Carson, Walid D. Fakhouri

Development. 2022 Aug 1; 149(15): dev200068. Published online 2022 Aug 8. doi: 10.1242/dev.200068

PMCID:: PMC9440756

Abstract Article

Select item 92058574.

Context-dependent enhancer function revealed by targeted inter-TAD relocation

Christopher Chase Bolt, Lucille Lopez-Delisle, Aurélie Hintermann, Bénédicte Mascrez, Antonella Rauseo, Guillaume Andrey, Denis Duboule

Nat Commun. 2022; 13: 3488. Published online 2022 Jun 17. doi: 10.1038/s41467-022-31241-3

PMCID:: PMC9205857

Abstract Article PDF–2.3M

Select item 87657555.

PRC1 sustains the integrity of neural fate in the absence of PRC2 function

Ayana Sawai, Sarah Pfennig, Milica Bulajić, Alexander Miller, Alireza Khodadadi-Jamayran, Esteban O Mazzoni, Jeremy S Dasen

eLife. 2022; 11: e72769. Published online 2022 Jan 7. doi: 10.7554/eLife.72769

PMCID:: PMC8765755

Abstract Article PDF–7.5M

Select item 85596746.

Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster

Ana Rita Amândio, Leonardo Beccari, Lucille Lopez-Delisle, Bénédicte Mascrez, Jozsef Zakany, Sandra Gitto, Denis Duboule

Genes Dev. 2021 Nov 1; 35(21-22): 1490–1509. doi: 10.1101/gad.348934.121

PMCID:: PMC8559674

Abstract Article PDF–22M

Select item 83739317.

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations

Christopher Chase Bolt, Lucille Lopez-Delisle, Bénédicte Mascrez, Denis Duboule

Nat Commun. 2021; 12: 5013. Published online 2021 Aug 18. doi: 10.1038/s41467-021-25330-y

PMCID:: PMC8373931

Abstract Article PDF–3.1M

Select item 83622918.

Geminin is required for Hox gene regulation to pattern the developing limb

Emily M.A. Lewis, Savita Sankar, Caili Tong, Ethan Patterson, Laura E. Waller, Paul Gontarz, Bo Zhang, David M. Ornitz, Kristen L. Kroll

Dev Biol. Author manuscript; available in PMC 2021 Aug 13.

Published in final edited form as: Dev Biol. 2020 Aug 1; 464(1): 11–23. Published online 2020 May 23. doi: 10.1016/j.ydbio.2020.05.007

PMCID:: PMC8362291

Abstract Article PDF–2.6M

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 770466610.

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster

Yoshiki Higashijima, Nao Nagai, Masamichi Yamamoto, Taro Kitazawa, Yumiko K. Kawamura, Akashi Taguchi, Natsuko Nakada, Masaomi Nangaku, Tetsushi Furukawa, Hiroyuki Aburatani, Hiroki Kurihara, Youichiro Wada, Yasuharu Kanki

Commun Biol. 2020; 3: 725. Published online 2020 Nov 30. doi: 10.1038/s42003-020-01456-5

PMCID:: PMC7704666

Abstract Article PDF–1.3M

Select item 725995111.

Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates

Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh, Hiroshi Asahara

eLife. 2020; 9: e53608. Published online 2020 May 29. doi: 10.7554/eLife.53608

PMCID:: PMC7259951

Abstract Article PDF–5.5M

Select item 719827912.

Development of the Proximal-Anterior Skeletal Elements in the Mouse Hindlimb Is Regulated by a Transcriptional and Signaling Network Controlled by Sall4

Katherine Q. Chen, Naoyuki Tahara, Aaron Anderson, Hiroko Kawakami, Sho Kawakami, Ryuichi Nishinakamura, Pier Paolo Pandolfi, Yasuhiko Kawakami

Genetics. 2020 May; 215(1): 129–141. Published online 2020 Mar 10. doi: 10.1534/genetics.120.303069

PMCID:: PMC7198279

Abstract Article PDF–2.0M

Select item 696949713.

The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13

Maria Félix Bastida, Rocío Pérez-Gómez, Anna Trofka, Jianjian Zhu, Alvaro Rada-Iglesias, Rushikesh Sheth, H. Scott Stadler, Susan Mackem, Marian A. Ros

Proc Natl Acad Sci U S A. 2020 Jan 14; 117(2): 1090–1096. Published online 2020 Jan 2. doi: 10.1073/pnas.1919470117

PMCID:: PMC6969497

Abstract Article PDF–1.1M

Select item 662636414.

Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes

Eddie Rodríguez-Carballo, Lucille Lopez-Delisle, Nayuta Yakushiji-Kaminatsui, Asier Ullate-Agote, Denis Duboule

BMC Biol. 2019; 17: 55. Published online 2019 Jul 12. doi: 10.1186/s12915-019-0677-x

PMCID:: PMC6626364

Abstract Article PDF–1.9M

Select item 661314715.

The constrained architecture of mammalian Hox gene clusters

Fabrice Darbellay, Célia Bochaton, Lucille Lopez-Delisle, Bénédicte Mascrez, Patrick Tschopp, Saskia Delpretti, Jozsef Zakany, Denis Duboule

Proc Natl Acad Sci U S A. 2019 Jul 2; 116(27): 13424–13433. Published online 2019 Jun 17. doi: 10.1073/pnas.1904602116

PMCID:: PMC6613147

Abstract Article PDF–2.5M

Select item 628359516.

Nayuta Yakushiji-Kaminatsui, Lucille Lopez-Delisle, Christopher Chase Bolt, Guillaume Andrey, Leonardo Beccari, Denis Duboule

PLoS Biol. 2018 Nov; 16(11): e3000004. Published online 2018 Nov 26. doi: 10.1371/journal.pbio.3000004

PMCID:: PMC6283595

Abstract Article PDF–3.1M

Select item 578541417.

PITX1 Promotes Chondrogenesis and Myogenesis in Mouse Hindlimbs Through Conserved Regulatory Targets

Jialiang S. Wang, Carlos R. Infante, Sungdae Park, Douglas B. Menke

Dev Biol. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Dev Biol. 2018 Feb 1; 434(1): 186–195. Published online 2017 Dec 20. doi: 10.1016/j.ydbio.2017.12.013

PMCID:: PMC5785414

Abstract Article PDF–1.6M

Select item 569771818.

Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13

Rushikesh Sheth, Iros Barozzi, David Langlais, Marco Osterwalder, Stephen Nemec, Hanqian L. Carlson, H. Scott Stadler, Axel Visel, Jacques Drouin, Marie Kmita

Cell Rep. Author manuscript; available in PMC 2017 Nov 21.

Published in final edited form as: Cell Rep. 2016 Dec 13; 17(11): 2913–2926. doi: 10.1016/j.celrep.2016.11.039

PMCID:: PMC5697718

Abstract Article PDF–2.2M

Select item 567692619.

Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr

Jozsef Zakany, Fabrice Darbellay, Bénédicte Mascrez, Anamaria Necsulea, Denis Duboule

Proc Natl Acad Sci U S A. 2017 Oct 31; 114(44): E9290–E9299. Published online 2017 Oct 17. doi: 10.1073/pnas.1712511114

PMCID:: PMC5676926

Abstract Article PDF–2.1M

Select item 515795120.

Hotair Is Dispensible for Mouse Development

Ana Rita Amândio, Anamaria Necsulea, Elisabeth Joye, Bénédicte Mascrez, Denis Duboule

PLoS Genet. 2016 Dec; 12(12): e1006232. Published online 2016 Dec 15. doi: 10.1371/journal.pgen.1006232

PMCID:: PMC5157951

Abstract Article PDF–2.6M

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