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Items: 1 to 20 of 155

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Crosstalk of HDAC4, PP1, and GSDMD in controlling pyroptosis
Weilv Xu, Qiao Jin, Xinyue Li, Danyue Li, Xinyu Fu, Nan Chen, Qian Lv, Yuhua Shi, Suhui He, Lu Dong, Yang Yang, Yuqi Yan, Fushan Shi
Cell Death Dis. 2024 Feb; 15(2): 115. Published online 2024 Feb 7. doi: 10.1038/s41419-024-06505-z
PMCID:
PMC10850491
AbstractArticlePDF–7.0M
3.
WTAP-Mediated m6A RNA Methylation Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via the miR-29b-3p/HDAC4 Axis
Jincheng Liu, Yunhao You, Zhenqian Sun, Lu Zhang, Xiang Li, Zihan Dai, Jinlong Ma, Yunzhen Chen, Guangjun Jiao
Stem Cells Transl Med. 2023 May; 12(5): 307–321. Published online 2023 Apr 3. doi: 10.1093/stcltm/szad020
PMCID:
PMC10184703
AbstractArticlePDF–61M
4.
Cytoplasmic HDAC4 recovers synaptic function in the 3×Tg mouse model of Alzheimer's disease
Claudia Colussi, Giuseppe Aceto, Cristian Ripoli, Alessia Bertozzi, Domenica Donatella Li Puma, Elena Paccosi, Marcello D'Ascenzo, Claudio Grassi
Neuropathol Appl Neurobiol. 2023 Feb; 49(1): e12861. Published online 2022 Nov 15. doi: 10.1111/nan.12861
PMCID:
PMC10099707
AbstractArticlePDF–2.4M
5.
SIK3–HDAC4 in the suprachiasmatic nucleus regulates the timing of arousal at the dark onset and circadian period in mice
Fuyuki Asano, Staci J. Kim, Tomoyuki Fujiyama, Chika Miyoshi, Noriko Hotta-Hirashima, Nodoka Asama, Kanako Iwasaki, Miyo Kakizaki, Seiya Mizuno, Michihiro Mieda, Fumihiro Sugiyama, Satoru Takahashi, Shoi Shi, Arisa Hirano, Hiromasa Funato, Masashi Yanagisawa
Proc Natl Acad Sci U S A. 2023 Mar 14; 120(11): e2218209120. Published online 2023 Mar 6. doi: 10.1073/pnas.2218209120
PMCID:
PMC10089210
AbstractArticlePDF–3.1M
6.
Sex and HDAC4 Differently Affect the Pathophysiology of Amyotrophic Lateral Sclerosis in SOD1-G93A Mice
Alessandra Renzini, Eva Pigna, Marco Rocchi, Alessia Cedola, Giuseppe Gigli, Viviana Moresi, Dario Coletti
Int J Mol Sci. 2023 Jan; 24(1): 98. Published online 2022 Dec 21. doi: 10.3390/ijms24010098
PMCID:
PMC9820722
AbstractArticlePDF–1.9M
7.
SP1 Promotes HDAC4 Expression and Inhibits HMGB1 Expression to Reduce Intestinal Barrier Dysfunction, Oxidative Stress, and Inflammatory Response after Sepsis
Zhen-Mi Liu, Xi Wang, Chen-Xi Li, Xue-Yan Liu, Xiao-Jing Guo, Yang Li, You-Lian Chen, Hong-Xing Ye, Huai-Sheng Chen
J Innate Immun. 2022 Jul; 14(4): 366–379. Published online 2022 Apr 22. doi: 10.1159/000518277
PMCID:
PMC9274949
AbstractArticlePDF–2.0M
8.
Histone Deacetylase 5 is a Phosphorylation Substrate of Protein Kinase D in Osteoclasts
Carina Mello Guimaraes Meyers, Samuel D Burciaga, Bora Faulkner, Parandis Kazemi, Jacob M Cohn, Kim C Mansky, Eric D Jensen
Bone. Author manuscript; available in PMC 2023 Jun 1.
Published in final edited form as: Bone. 2022 Jun; 159: 116393. Published online 2022 Mar 19. doi: 10.1016/j.bone.2022.116393
PMCID:
PMC9035101
AbstractArticlePDF–2.8M
9.
m6A demethylase ALKBH5 drives denervation‐induced muscle atrophy by targeting HDAC4 to activate FoxO3 signalling
Yuantong Liu, Tianjian Zhou, Qinghe Wang, Runhan Fu, Zengfu Zhang, Nandi Chen, Zhizhong Li, Guoyong Gao, Songlin Peng, Dazhi Yang
J Cachexia Sarcopenia Muscle. 2022 Apr; 13(2): 1210–1223. Published online 2022 Feb 9. doi: 10.1002/jcsm.12929
PMCID:
PMC8978003
AbstractArticlePDF–20M
10.
Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy
Alessandra Renzini, Nicoletta Marroncelli, Giorgia Cavioli, Silvia Di Francescantonio, Laura Forcina, Alessandro Lambridis, Eros Di Giorgio, Sergio Valente, Antonello Mai, Claudio Brancolini, Claudia Giampietri, Alessandra Magenta, Francesca De Santa, Sergio Adamo, Dario Coletti, Viviana Moresi
J Cachexia Sarcopenia Muscle. 2022 Apr; 13(2): 1339–1359. Published online 2022 Feb 15. doi: 10.1002/jcsm.12891
PMCID:
PMC8977968
AbstractArticlePDF–24M
11.
Hdac4 Regulates the Proliferation of Neural Crest-Derived Osteoblasts During Murine Craniofacial Development
Nayoung Ha, Jian Sun, Qian Bian, Dandan Wu, Xudong Wang
Front Physiol. 2022; 13: 819619. Published online 2022 Feb 15. doi: 10.3389/fphys.2022.819619
PMCID:
PMC8886889
AbstractArticlePDF–4.7M
12.
A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair
Sergio Velasco-Aviles, Nikiben Patel, Angeles Casillas-Bajo, Laura Frutos-Rincón, Enrique Velasco, Juana Gallar, Peter Arthur-Farraj, Jose A Gomez-Sanchez, Hugo Cabedo
eLife. 2022; 11: e72917. Published online 2022 Jan 25. doi: 10.7554/eLife.72917
PMCID:
PMC8853665
AbstractArticlePDF–42M
13.
Histone deacetylase 4 deletion results in abnormal chondrocyte hypertrophy and premature ossification from collagen type 2α1-expressing cells
Guoqing Du, Chuan Xiang, Xiaowen Sang, Xiang Wang, Ying Shi, Nan Wang, Shaowei Wang, Pengcui Li, Xiaochun Wei, Min Zhang, Lilan Gao, Hongsheng Zhan, Lei Wei
Mol Med Rep. 2020 Nov; 22(5): 4031–4040. Published online 2020 Aug 27. doi: 10.3892/mmr.2020.11465
PMCID:
PMC8369256
AbstractArticlePDF–948K
14.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
15.
HDAC4 induces the development of asthma by increasing Slug-upregulated CXCL12 expression through KLF5 deacetylation
Wendi Wei, Weida Chen, Naifeng He
J Transl Med. 2021; 19: 258. Published online 2021 Jun 12. doi: 10.1186/s12967-021-02812-7
PMCID:
PMC8199843
AbstractArticlePDF–1.1M
16.
Histone deacetylase 4 inhibits NF-κB activation by facilitating IκBα sumoylation
Qi Yang, Jielin Tang, Chonghui Xu, He Zhao, Yuan Zhou, Yanyi Wang, Min Yang, Xinwen Chen, Jizheng Chen
J Mol Cell Biol. 2020 Dec; 12(12): 933–945. Published online 2021 Feb 4. doi: 10.1093/jmcb/mjaa043
PMCID:
PMC7948076
AbstractArticlePDF–1.1M
17.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
18.
CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes
Kathryn G. Helmstadter, Senka Ljubojevic-Holzer, Brent M. Wood, Khanha D. Taheri, Simon Sedej, Jeffrey R. Erickson, Julie Bossuyt, Donald M. Bers
Basic Res Cardiol. 2021; 116(1): 11. Published online 2021 Feb 15. doi: 10.1007/s00395-021-00850-2
PMCID:
PMC7884572
AbstractArticlePDF–6.2M
19.
A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction
Tadatoshi Sato, Shiv Verma, Christian D. Castro Andrade, Maureen Omeara, Nia Campbell, Jialiang S. Wang, Murat Cetinbas, Audrey Lang, Brandon J. Ausk, Daniel J. Brooks, Ruslan I. Sadreyev, Henry M. Kronenberg, David Lagares, Yuhei Uda, Paola Divieti Pajevic, Mary L. Bouxsein, Ted S. Gross, Marc N. Wein
Nat Commun. 2020; 11: 3282. Published online 2020 Jul 1. doi: 10.1038/s41467-020-17099-3
PMCID:
PMC7329900
AbstractArticlePDF–3.7M
20.
Cardiomyocyte HIPK2 Maintains Basal Cardiac Function via ERK Signaling
Yuanjun Guo, Jennifer Y. Sui, Kyungsoo Kim, Zhentao Zhang, Xiaoyan A. Qu, Young-Jae Nam, Robert N. Willette, Joey V. Barnett, Bjorn C. Knollmann, Thomas Force, Hind Lal
Circulation. Author manuscript; available in PMC 2020 Nov 26.
Published in final edited form as: Circulation. 2019 Nov 26; 140(22): 1820–1833. Published online 2019 Oct 4. doi: 10.1161/CIRCULATIONAHA.119.040740
PMCID:
PMC7219521
AbstractArticlePDF–4.5M

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