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Items: 1 to 20 of 95

1.
Double somatic mutations in CTNNB1 and GNA11 in an aldosterone-producing adenoma
Kazutaka Nanba, Amy R. Blinder, Aaron M. Udager, Yuusuke Hirokawa, Takayoshi Miura, Hiroshi Okuno, Koki Moriyoshi, Yuto Yamazaki, Hironobu Sasano, Akihiro Yasoda, Noriko Satoh-Asahara, William E. Rainey, Tetsuya Tagami
Front Endocrinol (Lausanne) 2024; 15: 1286297. Published online 2024 Mar 5. doi: 10.3389/fendo.2024.1286297
PMCID:
PMC10948454
AbstractArticlePDF–6.0M
2.
GNA11 Variants Identified in Patients with Hypercalcemia or Hypocalcemia
Sarah A. Howles, Caroline M. Gorvin, Treena Cranston, Angela Rogers, Anna K. Gluck, Hannah Boon, Kate Gibson, Mushtaqur Rahman, Allen Root, M. Andrew Nesbit, Fadil M. Hannan, Rajesh V. Thakker
J Bone Miner Res. 2023 Jun; 38(6): 907–917. Published online 2023 Apr 18. doi: 10.1002/jbmr.4803
PMCID:
PMC10947407
AbstractArticlePDF–2.5M
3.
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021
PMCID:
PMC10617673
AbstractArticlePDF–3.6M
4.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
5.
Early‐onset hypertension associated with extensive cutaneous capillary malformations harboring postzygotic variants in GNAQ and GNA11
Olivia M. T. Davies, Ashley T. Ng, Jennifer Tran, Shoshana Blumenthal, Lisa M. Arkin, Amy J. Nopper, Catherine E. Cottrell, Maria Garzon, Dawn H. Siegel, Ilona J. Frieden, Beth A. Drolet
Pediatr Dermatol. 2022 Nov-Dec; 39(6): 914–919. Published online 2022 Aug 10. doi: 10.1111/pde.15103
PMCID:
PMC10087926
AbstractArticlePDF–1.0M
6.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
7.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
8.
LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression
Xuexue Xu, Pengsheng Ding, Lan Shi, Gang Wu, Xiaoling Ma
BMC Cancer. 2022; 22: 630. Published online 2022 Jun 8. doi: 10.1186/s12885-022-09680-4
PMCID:
PMC9175482
AbstractArticlePDF–15M
9.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
10.
Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause
Junhua Zhou, Elena A. B. Azizan, Claudia P. Cabrera, Fabio L. Fernandes-Rosa, Sheerazed Boulkroun, Giulia Argentesi, Emily Cottrell, Laurence Amar, Xilin Wu, Sam O’Toole, Emily Goodchild, Alison Marker, Russell Senanayake, Sumedha Garg, Tobias Åkerström, Samuel Backman, Suzanne Jordan, Satyamaanasa Polubothu, Daniel M. Berney, Anna Gluck, Kate E. Lines, Rajesh V. Thakker, Antoinette Tuthill, Caroline Joyce, Juan Pablo Kaski, Fiona E. Karet Frankl, Lou A. Metherell, Ada E. D. Teo, Mark Gurnell, Laila Parvanta, William M. Drake, Eva Wozniak, David Klinzing, Jyn Ling Kuan, Zenia Tiang, Celso E. Gomez Sanchez, Per Hellman, Roger S. Y. Foo, Charles A. Mein, Veronica A. Kinsler, Peyman Björklund, Helen L. Storr, Maria-Christina Zennaro, Morris J. Brown
Nat Genet. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Nat Genet. 2021 Sep; 53(9): 1360–1372. Published online 2021 Aug 12. doi: 10.1038/s41588-021-00906-y
PMCID:
PMC9082578
AbstractArticlePDF–3.2M
11.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
12.
A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins
Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux
Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611
PMCID:
PMC8951556
AbstractArticlePDF–4.4M
13.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
14.
Identification of a mosaic activating mutation in GNA11 in atypical Sturge-Weber Syndrome
Jeremy Thorpe, Laurence P. Frelin, Meghan McCann, Carlos A. Pardo, Bernard A. Cohen, Anne M. Comi, Jonathan Pevsner
J Invest Dermatol. Author manuscript; available in PMC 2022 Mar 1.
Published in final edited form as: J Invest Dermatol. 2021 Mar; 141(3): 685–688. Published online 2020 Aug 7. doi: 10.1016/j.jid.2020.03.978
PMCID:
PMC8483769
ArticlePDF–553K
15.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
16.
An experimental strategy to probe Gq contribution to signal transduction in living cells
Julian Patt, Judith Alenfelder, Eva Marie Pfeil, Jan Hendrik Voss, Nicole Merten, Funda Eryilmaz, Nina Heycke, Uli Rick, Asuka Inoue, Stefan Kehraus, Xavier Deupi, Christa E. Müller, Gabriele M. König, Max Crüsemann, Evi Kostenis
J Biol Chem. 2021 Jan-Jun; 296: 100472. Published online 2021 Feb 25. doi: 10.1016/j.jbc.2021.100472
PMCID:
PMC8024710
AbstractArticlePDF–3.4M
17.
AMPK, a key regulator of metabolism and autophagy, is activated by lysosomal damage via a novel galectin-directed ubiquitin signal transduction system
Jingyue Jia, Bhawana Bissa, Lukas Brecht, Lee Allers, Seong Won Choi, Yuexi Gu, Mark Zbinden, Mark R. Burge, Graham Timmins, Kenneth Hallows, Christian Behrends, Vojo Deretic
Mol Cell. Author manuscript; available in PMC 2021 Mar 5.
Published in final edited form as: Mol Cell. 2020 Mar 5; 77(5): 951–969.e9. Published online 2020 Jan 28. doi: 10.1016/j.molcel.2019.12.028
PMCID:
PMC7785494
AbstractArticlePDF–2.9M
18.
Dissecting Gq/11-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1
Kira Vanessa Blankenbach, Ralf Frederik Claas, Natalie Judith Aster, Anna Katharina Spohner, Sandra Trautmann, Nerea Ferreirós, Justin L. Black, John J. G. Tesmer, Stefan Offermanns, Thomas Wieland, Dagmar Meyer zu Heringdorf
Cells. 2020 Oct; 9(10): 2201. Published online 2020 Sep 29. doi: 10.3390/cells9102201
PMCID:
PMC7599897
AbstractArticlePDF–3.3M
19.
ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents
Wenjun Lan, Patricia Santofimia-Castaño, Mirna Swayden, Yi Xia, Zhengwei Zhou, Stephane Audebert, Luc Camoin, Can Huang, Ling Peng, Ana Jiménez-Alesanco, Adrián Velázquez-Campoy, Olga Abián, Gwen Lomberk, Raul Urrutia, Bruno Rizzuti, Vincent Geli, Philippe Soubeyran, José L. Neira, Juan Iovanna
JCI Insight. 2020 Sep 17; 5(18): e138117. Published online 2020 Sep 17. doi: 10.1172/jci.insight.138117
PMCID:
PMC7526551
AbstractArticlePDF–9.1M
20.
GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11
Dayana Abboud, Adrian F. Daly, Nadine Dupuis, Mohamed Ali Bahri, Asuka Inoue, Andy Chevigné, Fabien Ectors, Alain Plenevaux, Bernard Pirotte, Albert Beckers, Julien Hanson
Nat Commun. 2020; 11: 4752. Published online 2020 Sep 21. doi: 10.1038/s41467-020-18500-x
PMCID:
PMC7506554
AbstractArticlePDF–3.0M

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