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Items: 1 to 20 of 95

1.
PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis
Patrick Manetsch, Flurina Böhi, Kathrin Nowak, Deena M. Leslie Pedrioli, Michael O. Hottiger
Proc Natl Acad Sci U S A. 2023 Dec 5; 120(49): e2309047120. Published online 2023 Nov 27. doi: 10.1073/pnas.2309047120
PMCID:
PMC10710093
AbstractArticlePDF–12M
2.
Midline 1 interacting protein 1 promotes cancer metastasis through FOS-like 1-mediated matrix metalloproteinase 9 signaling in HCC
Yung-Tuen Chiu, Abdullah Husain, Karen Man-Fong Sze, Daniel Wai-Hung Ho, Eliana Mary Senires Suarez, Xia Wang, Eva Lee, Hoi-Tang Ma, Joyce Man-Fong Lee, Lo-Kong Chan, Irene Oi-Lin Ng
Hepatology. 2023 Nov; 78(5): 1368–1383. Published online 2023 Jan 13. doi: 10.1097/HEP.0000000000000266
PMCID:
PMC10581419
AbstractArticlePDF–3.2M
3.
Overexpression of FRA1 (FOSL1) Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression
Wuroud Al-khayyat, Jake Pirkkanen, Jessica Dougherty, Taylor Laframboise, Noah Dickinson, Neelam Khaper, Simon J. Lees, Marc S. Mendonca, Douglas R. Boreham, Tze Chun Tai, Christopher Thome, Sujeenthar Tharmalingam
Cells. 2023 Oct; 12(19): 2344. Published online 2023 Sep 24. doi: 10.3390/cells12192344
PMCID:
PMC10571788
AbstractArticlePDF–1.6M
4.
Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions
Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164
PMCID:
PMC10333884
AbstractArticlePDF–5.0M
5.
Loss of function of GATA3 regulates FRA1 and c-FOS to activate EMT and promote mammary tumorigenesis and metastasis
Xiong Liu, Feng Bai, Yuchan Wang, Chuying Wang, Ho Lam Chan, Chenglong Zheng, Jian Fang, Wei-Guo Zhu, Xin-Hai Pei
Cell Death Dis. 2023 Jun; 14(6): 370. Published online 2023 Jun 23. doi: 10.1038/s41419-023-05888-9
PMCID:
PMC10290069
AbstractArticlePDF–7.0M
6.
FRA-1 as a Regulator of EMT and Metastasis in Breast Cancer
Laura Casalino, Francesco Talotta, Ilenia Matino, Pasquale Verde
Int J Mol Sci. 2023 May; 24(9): 8307. Published online 2023 May 5. doi: 10.3390/ijms24098307
PMCID:
PMC10179602
AbstractArticlePDF–3.8M
7.
Recurrent FOSL1 rearrangements in desmoplastic fibroblastoma
Solange De Noon, Robert Piggott, Jamie Trotman, John A Tadross, Matthew Fittall, Debbie Hughes, Hongtao Ye, Emani Munasinghe, Matthew Murray, Roberto Tirabosco, Fernanda Amary, Nicholas Coleman, James Watkins, Michael Hubank, Patrick Tarpey, Sam Behjati, Adrienne M Flanagan
J Pathol. 2023 Feb; 259(2): 119–124. Published online 2023 Jan 3. doi: 10.1002/path.6038
PMCID:
PMC10107450
AbstractArticlePDF–3.9M
8.
FLI1 and FRA1 transcription factors drive the transcriptional regulatory networks characterizing muscle invasive bladder cancer
Perihan Yagmur Guneri-Sozeri, Gülden Özden-Yılmaz, Asli Kisim, Ece Cakiroglu, Aleyna Eray, Hamdiye Uzuner, Gökhan Karakülah, Devrim Pesen-Okvur, Serif Senturk, Serap Erkek-Ozhan
Commun Biol. 2023; 6: 199. Published online 2023 Feb 20. doi: 10.1038/s42003-023-04561-3
PMCID:
PMC9941102
AbstractArticlePDF–2.0M
9.
Synovial Fluid Derived from Human Knee Osteoarthritis Increases the Viability of Human Adipose-Derived Stem Cells through Upregulation of FOSL1
Hironori Kitajima, Takuya Sakamoto, Tetsuhiro Horie, Ayane Kuwano, Atsushi Fuku, Yasuhiko Taki, Yuka Nakamura, Ikuhiro Tanida, Hiroshi Sunami, Hiroaki Hirata, Yoshiyuki Tachi, Naoki Yamamoto, Yasuo Iida, Yasuhito Ishigaki, Sohsuke Yamada, Shigetaka Shimodaira, Yusuke Shimizu, Toru Ichiseki, Ayumi Kaneuji, Satoshi Osawa, Norio Kawahara
Cells. 2023 Jan; 12(2): 330. Published online 2023 Jan 15. doi: 10.3390/cells12020330
PMCID:
PMC9856741
AbstractArticlePDF–3.0M
10.
A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation
Ankitha Shetty, Subhash Kumar Tripathi, Sini Junttila, Tanja Buchacher, Rahul Biradar, Santosh D Bhosale, Tapio Envall, Asta Laiho, Robert Moulder, Omid Rasool, Sanjeev Galande, Laura L Elo, Riitta Lahesmaa
Nucleic Acids Res. 2022 May 20; 50(9): 4938–4958. Published online 2022 May 3. doi: 10.1093/nar/gkac256
PMCID:
PMC9122603
AbstractArticlePDF–5.6M
11.
Role of the Transcription Factor FOSL1 in Organ Development and Tumorigenesis
Vladimir V. Sobolev, Asiat Z. Khashukoeva, Olga E. Evina, Natalia A. Geppe, Svetlana N. Chebysheva, Irina M. Korsunskaya, Ekaterina Tchepourina, Alexandre Mezentsev
Int J Mol Sci. 2022 Feb; 23(3): 1521. Published online 2022 Jan 28. doi: 10.3390/ijms23031521
PMCID:
PMC8835756
AbstractArticlePDF–1.6M
12.
Pharmacological Inhibition of Core Regulatory Circuitry Liquid–liquid Phase Separation Suppresses Metastasis and Chemoresistance in Osteosarcoma
Bing Lu, Changye Zou, Meiling Yang, Yangyang He, Jincan He, Chuanxia Zhang, Siyun Chen, Jiaming Yu, Kilia Yun Liu, Qi Cao, Wei Zhao
Adv Sci (Weinh) 2021 Oct; 8(20): 2101895. Published online 2021 Aug 25. doi: 10.1002/advs.202101895
PMCID:
PMC8529446
AbstractArticlePDF–5.3M
13.
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
Carolina Marques, Thomas Unterkircher, Paula Kroon, Barbara Oldrini, Annalisa Izzo, Yuliia Dramaretska, Roberto Ferrarese, Eva Kling, Oliver Schnell, Sven Nelander, Erwin F Wagner, Latifa Bakiri, Gaetano Gargiulo, Maria Stella Carro, Massimo Squatrito
eLife. 2021; 10: e64846. Published online 2021 Aug 17. doi: 10.7554/eLife.64846
PMCID:
PMC8370767
AbstractArticlePDF–6.5M
14.
FOSL1 promotes metastasis of head and neck squamous cell carcinoma through super-enhancer-driven transcription program
Ming Zhang, Rosalie G. Hoyle, Zhikun Ma, Bo Sun, Weixin Cai, Hongshi Cai, Nan Xie, Yadong Zhang, Jinsong Hou, Xiqiang Liu, Demeng Chen, Glen E. Kellogg, Hisashi Harada, Yue Sun, Cheng Wang, Jiong Li
Mol Ther. 2021 Aug 4; 29(8): 2583–2600. Published online 2021 Mar 29. doi: 10.1016/j.ymthe.2021.03.024
PMCID:
PMC8353207
AbstractArticlePDF–5.9M
15.
SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization
Chao Dai, Jonathan P. Rennhack, Taylor E. Arnoff, Maneesha Thaker, Scott T. Younger, John G. Doench, August Yue Huang, Annan Yang, Andrew J. Aguirre, Belinda Wang, Evan Mun, Joyce T. O’Connell, Ying Huang, Katherine Labella, Jessica A. Talamas, Ji Li, Nina Ilic, Justin Hwang, Andrew L. Hong, Andrew O. Giacomelli, Ole Gjoerup, David E. Root, William C. Hahn
Cell Rep. Author manuscript; available in PMC 2021 Aug 9.
Published in final edited form as: Cell Rep. 2021 Jul 27; 36(4): 109443. doi: 10.1016/j.celrep.2021.109443
PMCID:
PMC8350598
AbstractArticlePDF–1.2M
16.
The role of FOSL1 in stem-like cell reprogramming processes
Valeria Pecce, Antonella Verrienti, Giulia Fiscon, Marialuisa Sponziello, Federica Conte, Luana Abballe, Cosimo Durante, Lorenzo Farina, Sebastiano Filetti, Paola Paci
Sci Rep. 2021; 11: 14677. Published online 2021 Jul 19. doi: 10.1038/s41598-021-94072-0
PMCID:
PMC8290037
AbstractArticlePDF–3.3M
17.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
18.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
19.
Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers
Fabienne Bejjani, Claire Tolza, Mathias Boulanger, Damien Downes, Raphaël Romero, Muhammad Ahmad Maqbool, Amal Zine El Aabidine, Jean-Christophe Andrau, Sophie Lebre, Laurent Brehelin, Hughes Parrinello, Marine Rohmer, Tony Kaoma, Laurent Vallar, Jim R Hughes, Kazem Zibara, Charles-Henri Lecellier, Marc Piechaczyk, Isabelle Jariel-Encontre
Nucleic Acids Res. 2021 Mar 18; 49(5): 2488–2508. Published online 2021 Feb 3. doi: 10.1093/nar/gkab053
PMCID:
PMC7968996
AbstractArticlePDF–4.6M
20.
Lipopolysaccharide Affects the Proliferation and Glucose Metabolism of Cervical Cancer Cells Through the FRA1/MDM2/p53 Pathway
Xiaoyan Jiang, Jing Yuan, Yingyu Dou, Da Zeng, Songshu Xiao
Int J Med Sci. 2021; 18(4): 1030–1038. Published online 2021 Jan 1. doi: 10.7150/ijms.47360
PMCID:
PMC7807182
AbstractArticlePDF–1.5M

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