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Select item 109934991.

Shank3 deficiency elicits autistic-like behaviors by activating p38α in hypothalamic AgRP neurons

Shanshan Wu, Jing Wang, Zicheng Zhang, Xinchen Jin, Yang Xu, Youwen Si, Yixiao Liang, Yueping Ge, Huidong Zhan, Li peng, Wenkai Bi, Dandan Luo, Mengzhu Li, Bo Meng, Qingbo Guan, Jiajun Zhao, Ling Gao, Zhao He

Mol Autism. 2024; 15: 14. Published online 2024 Apr 3. doi: 10.1186/s13229-024-00595-4

PMCID:: PMC10993499

Abstract Article PDF–19M

Select item 108643632.

Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy

Yan Guo, Pan Xiang, Xiaojiao Sun, Wei Liu, Jiafeng Zhou, Bin Yin, Lin Hou, Boqin Qiang, Huiliang Li, Pengcheng Shu, Xiaozhong Peng

Signal Transduct Target Ther. 2024; 9: 32. Published online 2024 Feb 14. doi: 10.1038/s41392-024-01742-2

PMCID:: PMC10864363

Abstract Article PDF–9.9M

Select item 107869573.

The P38MAPK/ATF2 signaling pathway is involved in PND in mice

Mengjiao Zhu, Si Long, Yizhi Tao, Zhifa Zhang, Zhiqiang Zhou, Xueren Wang, Wei Chen

Exp Brain Res. 2024; 242(1): 109–121. Published online 2023 Nov 16. doi: 10.1007/s00221-023-06730-6

PMCID:: PMC10786957

Abstract Article PDF–1.8M

Select item 107514434.

TAZ stimulates exercise‐induced muscle satellite cell activation via Pard3–p38 MAPK–TAZ signalling axis

Kyung Min Kim, Gi Don Yoo, Woong Heo, Ho Taek Oh, Jeekeon Park, Somin Shin, Youjin Do, Mi Gyeong Jeong, Eun Sook Hwang, Jeong‐Ho Hong

J Cachexia Sarcopenia Muscle. 2023 Dec; 14(6): 2733–2746. Published online 2023 Nov 3. doi: 10.1002/jcsm.13348

PMCID:: PMC10751443

Abstract Article PDF–2.6M

Select item 106435325.

The lncRNA MEG3/miRNA-21/P38MAPK axis inhibits coxsackievirus 3 replication in acute viral myocarditis

Feng He, Zhuo Liu, Miao Feng, Zonghui Xiao, Xiaoyu Yi, Jianxin Wu, Zhewei Liu, Gaoyu Wang, Le Li, Hailan Yao

Virus Res. 2024 Jan 2; 339: 199250. Published online 2023 Nov 1. doi: 10.1016/j.virusres.2023.199250

PMCID:: PMC10643532

Abstract Article PDF–4.2M

Select item 105828876.

C-reactive protein impairs immune response of CD8⁺ T cells via FcγRIIb-p38MAPK-ROS axis in multiple myeloma

Jinxing Jiang, Ziyi Peng, Junying Wang, Mengping Chen, Yike Wan, Honghui Huang, Zhiqiang Liu, Jingya Wang, Jian Hou

J Immunother Cancer. 2023; 11(10): e007593. Published online 2023 Oct 15. doi: 10.1136/jitc-2023-007593

Correction in:: J Immunother Cancer. 2023; 11(12): e007593corr1.

PMCID:: PMC10582887

Abstract Article PDF–5.1M

Select item 104998797.

Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development

Yongzhen Lai, Yan Guo, Caiyu Liao, Chuanqing Mao, Jing Liu, Chengyan Ren, Wen Yang, Lin Luo, Weihui Chen

Sci Rep. 2023; 13: 15170. Published online 2023 Sep 13. doi: 10.1038/s41598-023-42423-4

PMCID:: PMC10499879

Abstract Article PDF–6.8M

Select item 104787538.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 102404239.

Pregranulosa cell–derived FGF23 protects oocytes from premature apoptosis during primordial follicle formation by inhibiting p38 MAPK in mice

Zijian Zhu, Shaogang Qin, Tuo Zhang, Meina He, Wenying Zheng, Ting Zhao, Meng Gao, Ziqi Chen, Bo Zhou, Guoliang Xia, Chao Wang

J Biol Chem. 2023 Jun; 299(6): 104776. Published online 2023 May 2. doi: 10.1016/j.jbc.2023.104776

PMCID:: PMC10240423

Abstract Article PDF–4.6M

Select item 1023864910.

p38MAPKα stromal reprogramming sensitizes metastatic breast cancer to immunotherapy

Douglas V. Faget, Xianmin Luo, Matthew J. Inkman, Qihao Ren, Xinming Su, Kai Ding, Michael R. Waters, Ganesh Kumar Raut, Gaurav Pandey, Paarth B. Dodhiawala, Renata Ramalho-Oliveira, Jiayu Ye, Thomas Cole, Bhavna Murali, Alexander Zheleznyak, Monica Shokeen, Kurt R. Weiss, Joseph B. Monahan, Carl J. DeSelm, Adrian V. Lee, Steffi Oesterreich, Katherine N. Weilbaecher, Jin Zhang, David G. DeNardo, Sheila A. Stewart

Cancer Discov. Author manuscript; available in PMC 2023 Dec 2.

Published in final edited form as: Cancer Discov. 2023 Jun 2; 13(6): 1454–1477. doi: 10.1158/2159-8290.CD-22-0907

PMCID:: PMC10238649

Abstract Article PDF–3.1M

Select item 1023177311.

Early chronic suppression of microglial p38α in a model of Alzheimer’s disease does not significantly alter amyloid-associated neuropathology

David J. Braun, Hilaree N. Frazier, Verda A. Davis, Meggie J. Coleman, Colin B. Rogers, Linda J. Van Eldik

PLoS One. 2023; 18(5): e0286495. Published online 2023 May 31. doi: 10.1371/journal.pone.0286495

PMCID:: PMC10231773

Abstract Article PDF–2.7M

Select item 1009133912.

P38 MAPK activated ADAM17 mediates ACE2 shedding and promotes cardiac remodeling and heart failure after myocardial infarction

Qi Chen, Yilan Li, Bike Bie, Bin Zhao, Yanxiu Zhang, Shaohong Fang, Shuijie Li, Yao Zhang

Cell Commun Signal. 2023; 21: 73. Published online 2023 Apr 12. doi: 10.1186/s12964-023-01087-3

PMCID:: PMC10091339

Abstract Article PDF–12M

Select item 1007976113.

SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice

Guo Zheng, Yu Su, Li Wei, Yingcheng Yao, Yizhe Wang, Xiaoting Luo, Xing Wang, Xiong Z. Ruan, Danyang Li, Yaxi Chen

Cell Death Dis. 2023 Apr; 14(4): 249. Published online 2023 Apr 6. doi: 10.1038/s41419-023-05754-8

PMCID:: PMC10079761

Abstract Article PDF–9.1M

Select item 1002550714.

Involvement of p38 MAPK in Leydig cell aging and age-related decline in testosterone

Dandan Luo, Xiangyu Qi, Xiaoqin Xu, Leilei Yang, Chunxiao Yu, Qingbo Guan

Front Endocrinol (Lausanne) 2023; 14: 1088249. Published online 2023 Mar 6. doi: 10.3389/fendo.2023.1088249

PMCID:: PMC10025507

Abstract Article PDF–4.7M

Select item 1002516315.

p38 MAPK and MKP-1 control the glycolytic program via the bifunctional glycolysis regulator PFKFB3 during sepsis

Carli E. Mager, Justin M. Mormol, Evan D. Shelton, Parker R. Murphy, Bridget A. Bowman, Timothy J. Barley, Xiantao Wang, Sarah C. Linn, Kevin Liu, Leif D. Nelin, Markus Hafner, Yusen Liu

J Biol Chem. 2023 Apr; 299(4): 103043. Published online 2023 Feb 17. doi: 10.1016/j.jbc.2023.103043

PMCID:: PMC10025163

Abstract Article PDF–2.8M

Select item 999836616.

LncRNA U90926 is induced in activated macrophages, is protective in endotoxic shock, and encodes a novel secreted protein

Bristy Sabikunnahar, Sydney Caldwell, Stella Varnum, Tyler Hogan, Alexei Cooper, Karolyn G. Lahue, Joseph J. Bivona, III, Phoebe Cousens, Menelaos Symeonides, Bryan A. Ballif, Matthew E. Poynter, Dimitry N. Krementsov

J Immunol. Author manuscript; available in PMC 2024 Mar 15.

Published in final edited form as: J Immunol. 2023 Mar 15; 210(6): 807–819. doi: 10.4049/jimmunol.2200215

PMCID:: PMC9998366

Abstract Article PDF–2.1M

Select item 996655017.

Notch1 Is Involved in Physiologic Cardiac Hypertrophy of Mice via the p38 Signaling Pathway after Voluntary Running

Weiwei Zhang, Jiayi Liu, Zekang Wu, Guanwei Fan, Zhuo Yang, Chunhua Liu

Int J Mol Sci. 2023 Feb; 24(4): 3212. Published online 2023 Feb 6. doi: 10.3390/ijms24043212

PMCID:: PMC9966550

Abstract Article PDF–2.5M

Select item 954247218.

Cardiomyocyte p38 MAPKα suppresses a heart–adipose tissue–neutrophil crosstalk in heart failure development

Katharina Bottermann, Lisa Kalfhues, Rianne Nederlof, Anne Hemmers, Lucia M. Leitner, Vici Oenarto, Jana Nemmer, Mirjam Pfeffer, Vidisha Raje, Rene Deenen, Patrick Petzsch, Heba Zabri, Karl Köhrer, Andreas S. Reichert, Maria Grandoch, Jens W. Fischer, Diran Herebian, Johannes Stegbauer, Thurl E. Harris, Axel Gödecke

Basic Res Cardiol. 2022; 117(1): 48. Published online 2022 Oct 7. doi: 10.1007/s00395-022-00955-2