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Select item 111370191.

G protein-specific mechanisms in the serotonin 5-HT_2A receptor regulate psychosis-related effects and memory deficits

Elk Kossatz, Rebeca Diez-Alarcia, Supriya A. Gaitonde, Carla Ramon-Duaso, Tomasz Maciej Stepniewski, David Aranda-Garcia, Itziar Muneta-Arrate, Elodie Tepaz, Suwipa Saen-Oon, Robert Soliva, Aida Shahraki, David Moreira, Jose Brea, Maria Isabel Loza, Rafael de la Torre, Peter Kolb, Michel Bouvier, J. Javier Meana, Patricia Robledo, Jana Selent

Nat Commun. 2024; 15: 4307. Published online 2024 May 29. doi: 10.1038/s41467-024-48196-2

PMCID:: PMC11137019

Abstract Article PDF–2.7M

Select item 110456502.

Fibroblast expression of neurotransmitter receptor HTR2A associates with inflammation in rheumatoid arthritis joint

Chunyan Xiang, Soon-Min Hong, Bingjiao Zhao, Hui Pi, Fang Du, Xingyu Lu, Yuanjia Tang, Nan Shen, Chunxi Yang, Runci Wang

Clin Exp Med. 2024; 24(1): 84. Published online 2024 Apr 25. doi: 10.1007/s10238-024-01352-w

PMCID:: PMC11045650

Abstract Article PDF–7.5M

Select item 109889273.

Interaction between HTR2A rs3125 and negative life events in suicide attempts among patients with major depressive disorder: a cross-sectional study

Jian-Yue Pang, Yi-Ping Wang, Hui-Min Teng, Jin He, Rui Luo, Si-Meng Feng, Wei-Hua Yue, Heng-Fen Li

BMC Psychiatry. 2024; 24: 249. Published online 2024 Apr 2. doi: 10.1186/s12888-024-05713-3

PMCID:: PMC10988927

Abstract Article PDF–1.1M

Select item 107268634.

Genetic variation of the 5‐HT1A rs6295, 5‐HT2A rs6311, and CNR1 rs1049353 and an altered endocannabinoid system in depressed patients

Jasmin Obermanns, Hanna Meiser, Saskia Hoberg, Cynthia Segura Vesterager, Frank Schulz, Georg Juckel, Barbara Emons

Brain Behav. 2023 Dec; 13(12): e3323. Published online 2023 Nov 20. doi: 10.1002/brb3.3323

PMCID:: PMC10726863

Abstract Article PDF–331K

Select item 106472455.

In Vivo Serotonin 5-HT2A Receptor Availability and Its Relationship with Aggression Traits in Healthy Individuals: A Positron Emission Tomography Study with C-11 MDL100907

Jeong-Hee Kim, Hang-Keun Kim, Young-Don Son, Jong-Hoon Kim

Int J Mol Sci. 2023 Nov; 24(21): 15697. Published online 2023 Oct 28. doi: 10.3390/ijms242115697

PMCID:: PMC10647245

Abstract Article PDF–2.5M

Select item 105102976.

Association between the rs6313 polymorphism in the 5-HTR2A gene and the efficacy of antipsychotic drugs

Yulong Wang, Xingru Tan, Zhoufangyuan Chen, Bide Zhang, Yunzhi Gao, Yanlong Wang

BMC Psychiatry. 2023; 23: 682. Published online 2023 Sep 19. doi: 10.1186/s12888-023-05165-1

PMCID:: PMC10510297

Abstract Article PDF–2.0M

Select item 104111907.

Prognostic and immunomodulatory roles of schizophrenia-associated genes HTR2A, COMT, and PRODH in pan-cancer analysis and glioma survival prediction model

Jing Shen, Qiang Wang, Fengquan Lu, Hua Xu, Peng Wang, Yu Feng

Front Immunol. 2023; 14: 1201252. Published online 2023 Jul 26. doi: 10.3389/fimmu.2023.1201252

PMCID:: PMC10411190

Abstract Article PDF–15M

Select item 102160778.

Platelet Serotonin (5-HT) Concentration, Platelet Monoamine Oxidase B (MAO-B) Activity and HTR2A, HTR2C, and MAOB Gene Polymorphisms in Asthma

Marcela Konjevod, Katherina B. Sreter, Sanja Popovic-Grle, Marina Lampalo, Lucija Tudor, Irena Jukic, Gordana Nedic Erjavec, Jasna Bingulac-Popovic, Hana Safic Stanic, Matea Nikolac Perkovic, Jasenka Markeljevic, Miroslav Samarzija, Nela Pivac, Dubravka Svob Strac

Biomolecules. 2023 May; 13(5): 800. Published online 2023 May 8. doi: 10.3390/biom13050800

PMCID:: PMC10216077

Abstract Article PDF–1.0M

Select item 101030099.

The crosstalk between 5-HT_2AR and mGluR2 in schizophrenia

Somdatta Saha, Javier González-Maeso

Neuropharmacology. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Neuropharmacology. 2023 Jun 1; 230: 109489. Published online 2023 Mar 6. doi: 10.1016/j.neuropharm.2023.109489

PMCID:: PMC10103009

Abstract Article PDF–1.6M

Select item 991815210.

Expression Patterns of Serotonin Receptors 5-HT1A, 5-HT2A, and 5-HT3A during Human Fetal Lung Development

Jelena Nikolić, Katarina Vukojević, Violeta Šoljić, Josip Mišković, Martina Orlović Vlaho, Mirna Saraga-Babić, Natalija Filipović

Int J Mol Sci. 2023 Feb; 24(3): 2965. Published online 2023 Feb 3. doi: 10.3390/ijms24032965

PMCID:: PMC9918152

Abstract Article PDF–15M

Select item 976330411.

Circulating methylation level of HTR2A is associated with inflammation and disease activity in rheumatoid arthritis

Jianan Zhao, Lingxia Xu, Cen Chang, Ping Jiang, Kai Wei, Yiming Shi, Linshuai Xu, Yixin Zheng, Yu Shan, Yanqin Bian, Li Li, Shicheng Guo, Steven J. Schrodi, Rongsheng Wang, Dongyi He

Front Immunol. 2022; 13: 1054451. Published online 2022 Dec 6. doi: 10.3389/fimmu.2022.1054451

PMCID:: PMC9763304

Abstract Article PDF–4.8M

Select item 954304912.

Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse

Aysheh Alrfooh, Ryan M. Smith

Epigenetics. 2022; 17(10): 1246–1258. Published online 2021 Nov 23. doi: 10.1080/15592294.2021.2005277

PMCID:: PMC9543049

Abstract Article PDF–978K

Select item 944452413.

Polymorphisms in the 5-HTR2A gene related to obstructive sleep apnea syndrome

Vânia Belintani Piatto, Thiago Bittencourt Ottoni de Carvalho, Nely Silva Aragão de Marchi, Fernando Drimel Molina, José Victor Maniglia

Braz J Otorhinolaryngol. 2011 May-Jun; 77(3): 348–355. Published online 2015 Oct 19. doi: 10.1590/S1808-86942011000300013

PMCID:: PMC9444524

Abstract Article PDF–240K

Select item 920866214.

ELEVATED 5-HT 2A RECEPTORS IN POSTMORTEM PREFRONTAL CORTEX IN MAJOR DEPRESSION IS ASSOCIATED WITH REDUCED ACTIVITY OF PROTEIN KINASE A

R. C. SHELTON, E. SANDERS-BUSH, D. H. MANIER, D. A. LEWIS

Neuroscience. Author manuscript; available in PMC 2022 Jun 20.

Published in final edited form as: Neuroscience. 2009 Feb 18; 158(4): 1406–1415. Published online 2008 Dec 3. doi: 10.1016/j.neuroscience.2008.11.036

PMCID:: PMC9208662

Abstract Article PDF–437K

Select item 874537615.

Possible association of serotonin 2A receptor gene (HTR2A) regulatory variants with severity of depression symptoms in children with autism spectrum disorder

Kenneth D. Gadow, Ryan M. Smith, Julia K. Pinsonneault

Cogn Behav Neurol. Author manuscript; available in PMC 2022 Jan 10.

Published in final edited form as: Cogn Behav Neurol. 2014 Jun; 27(2): 107–116. doi: 10.1097/WNN.0000000000000028

PMCID:: PMC8745376

Abstract Article PDF–532K

Select item 849287616.

Serotonin 5-HT_2A receptor activity mediates adipocyte differentiation through control of adipogenic gene expression

Bangning Yu, Diana M. Battaglia, Timothy P. Foster, Charles D. Nichols

Sci Rep. 2021; 11: 19714. Published online 2021 Oct 5. doi: 10.1038/s41598-021-98970-1

PMCID:: PMC8492876

Abstract Article PDF–1.7M

Select item 813794717.

Opposite alterations of 5HT_2A receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile

Rebeca Diez-Alarcia, Carolina Muguruza, Guadalupe Rivero, Aintzane García-Bea, Vanessa Gómez-Vallejo, Luis F. Callado, Jordi Llop, Abraham Martín, J. Javier Meana

Transl Psychiatry. 2021; 11: 302. Published online 2021 May 20. doi: 10.1038/s41398-021-01430-7

PMCID:: PMC8137947

Abstract Article PDF–940K

Select item 774772118.

Epigenetic differences at the HTR2A locus in progressive multiple sclerosis patients

Vicki E. Maltby, Rodney A. Lea, Sean Burnard, Alexandre Xavier, Thao Van Cao, Nicole White, Daniel Kennedy, Kira Groen, Katherine A. Sanders, Rebecca Seeto, Samara Bray, Melissa Gresle, Louise Laverick, Helmut Butzkueven, Rodney J. Scott, Jeannette Lechner-Scott

Sci Rep. 2020; 10: 22217. Published online 2020 Dec 17. doi: 10.1038/s41598-020-78809-x

PMCID:: PMC7747721

Abstract Article PDF–1.4M

Select item 772878619.

Serotonin 2A (5-HT_2A) receptor affects cell–matrix adhesion and the formation and maintenance of stress fibers in HEK293 cells

Joe Anand Kumar John Jayakumar, Mitradas. M. Panicker, Basudha Basu

Sci Rep. 2020; 10: 21675. Published online 2020 Dec 10. doi: 10.1038/s41598-020-78595-6

PMCID:: PMC7728786

Abstract Article PDF–1.5M

Select item 771764820.

Interclass GPCR heteromerization affects localization and trafficking

Rudy Toneatti, Jong M. Shin, Urjita H. Shah, Carl R. Mayer, Justin M. Saunders, Miguel Fribourg, Paul T. Arsenovic, William G. Janssen, Stuart C. Sealfon, Juan F. López-Giménez, Deanna L. Benson, Daniel E. Conway, Javier González-Maeso

Sci Signal. Author manuscript; available in PMC 2021 Apr 20.

Published in final edited form as: Sci Signal. 2020 Oct 20; 13(654): eaaw3122. Published online 2020 Oct 20. doi: 10.1126/scisignal.aaw3122