PMC Links for GEO Profiles (Select 22465471) - PMC

Links from GEO Profiles

Items: 1 to 20 of 78

<< First< Prev

Page of 4

Select item 109121981.

NDUFS4 regulates cristae remodeling in diabetic kidney disease

Koki Mise, Jianyin Long, Daniel L. Galvan, Zengchun Ye, Guizhen Fan, Rajesh Sharma, Irina I. Serysheva, Travis I. Moore, Collene R. Jeter, M. Anna Zal, Motoo Araki, Jun Wada, Paul T. Schumacker, Benny H. Chang, Farhad R. Danesh

Nat Commun. 2024; 15: 1965. Published online 2024 Mar 4. doi: 10.1038/s41467-024-46366-w

Correction in:: Nat Commun. 2024; 15: 3022.

PMCID:: PMC10912198

Article PDF–6.2M

Select item 108974352.

Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4^−/− mouse

Zhan Yin, Ahmed-Noor A Agip, Hannah R Bridges, Judy Hirst

EMBO J. 2024 Jan; 43(2): 225–249. Published online 2024 Jan 2. doi: 10.1038/s44318-023-00001-4

PMCID:: PMC10897435

Article PDF–12M

Select item 106216163.

Elevated susceptibility to exogenous seizure triggers and impaired interneuron excitability in a mouse model of Leigh syndrome epilepsy

Arena Manning, Victor Han, Alexa Stephens, Rose Wang, Nicholas Bush, Michelle Bard, Jan M. Ramirez, Franck Kalume

Neurobiol Dis. Author manuscript; available in PMC 2023 Nov 2.

Published in final edited form as: Neurobiol Dis. 2023 Oct 15; 187: 106288. Published online 2023 Sep 11. doi: 10.1016/j.nbd.2023.106288

PMCID:: PMC10621616

Article PDF–2.1M

Select item 106187964.

Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency

Gerardo G. Piroli, Allison M. Manuel, Richard S. McCain, Holland H. Smith, Oliver Ozohanics, Sara Mellid, J. Hunter Cox, William E. Cotham, Michael D. Walla, Alberto Cascón, Attila Ambrus, Norma Frizzell

Redox Biol. 2023 Nov; 67: 102932. Published online 2023 Oct 17. doi: 10.1016/j.redox.2023.102932

PMCID:: PMC10618796

Article PDF–8.3M

Select item 99382165.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Article PDF–5.3M

Select item 95446866.

Microglial response promotes neurodegeneration in the Ndufs4 KO mouse model of Leigh syndrome

Kevin Aguilar, Gemma Comes, Carla Canal, Albert Quintana, Elisenda Sanz, Juan Hidalgo

Glia. 2022 Nov; 70(11): 2032–2044. Published online 2022 Jun 30. doi: 10.1002/glia.24234

PMCID:: PMC9544686

Article PDF–8.3M

Select item 93605347.

Noninvasive Ophthalmic Imaging Measures Retinal Degeneration and Vision Deficits in Ndufs4^−/− Mouse Model of Mitochondrial Complex I Deficiency

Maria I. Avrutsky, Jacqueline M. Lawson, Jade E. Smart, Claire W. Chen, Carol M. Troy

Transl Vis Sci Technol. 2022 Aug; 11(8): 5. Published online 2022 Aug 3. doi: 10.1167/tvst.11.8.5

PMCID:: PMC9360534

Article PDF–8.2M

Select item 93292048.

Isoflurane inhibition of endocytosis is an anesthetic mechanism of action

Sangwook Jung, Pavel I Zimin, Christian B Woods, Ernst-Bernhard Kayser, Dominik Haddad, Colleen R Reczek, Ken Nakamura, Jan-Marino Ramirez, Margaret M Sedensky, Philip G Morgan

Curr Biol. Author manuscript; available in PMC 2023 Jul 25.

Published in final edited form as: Curr Biol. 2022 Jul 25; 32(14): 3016–3032.e3. Published online 2022 Jun 9. doi: 10.1016/j.cub.2022.05.037

PMCID:: PMC9329204

Article PDF–2.8M

Select item 89671079.

Ndufs4 knockout mouse models of Leigh syndrome: pathophysiology and intervention

Melissa A E van de Wal, Merel J W Adjobo-Hermans, Jaap Keijer, Tom J J Schirris, Judith R Homberg, Mariusz R Wieckowski, Sander Grefte, Evert M van Schothorst, Clara van Karnebeek, Albert Quintana, Werner J H Koopman

Brain. 2022 Jan; 145(1): 45–63. Published online 2021 Nov 29. doi: 10.1093/brain/awab426

PMCID:: PMC8967107

Article PDF–1.8M

Select item 890069710.

Adipose Mitochondrial Complex I Deficiency Modulates Inflammation and Glucose Homeostasis in a Sex-Dependent Manner

Kyung-Mi Choi, Karen K Ryan, John C Yoon

Endocrinology. 2022 Apr; 163(4): bqac018. Published online 2022 Feb 16. doi: 10.1210/endocr/bqac018

PMCID:: PMC8900697

Article

Select item 848925611.

Hypoxia ameliorates brain hyperoxia and NAD⁺ deficiency in a murine model of Leigh syndrome

Robert M. H. Grange, Rohit Sharma, Hardik Shah, Bryn Reinstadler, Olga Goldberger, Marissa K. Cooper, Akito Nakagawa, Yusuke Miyazaki, Allyson G. Hindle, Annabelle J. Batten, Gregory R. Wojtkiewicz, Grigorij Schleifer, Aranya Bagchi, Eizo Marutani, Rajeev Malhotra, Donald B. Bloch, Fumito Ichinose, Vamsi K. Mootha, Warren M. Zapol

Mol Genet Metab. Author manuscript; available in PMC 2021 Oct 4.

Published in final edited form as: Mol Genet Metab. 2021 May; 133(1): 83–93. Published online 2021 Mar 11. doi: 10.1016/j.ymgme.2021.03.005

PMCID:: PMC8489256

Article PDF–764K

Select item 829197112.

Mechanisms underlying neonate-specific metabolic effects of volatile anesthetics

Julia Stokes, Arielle Freed, Rebecca Bornstein, Kevin N Su, John Snell, Amanda Pan, Grace X Sun, Kyung Yeon Park, Sangwook Jung, Hailey Worstman, Brittany M Johnson, Philip G Morgan, Margaret M Sedensky, Simon C Johnson

eLife. 2021; 10: e65400. Published online 2021 Jul 13. doi: 10.7554/eLife.65400

PMCID:: PMC8291971

Article PDF–4.2M

Select item 815511613.

Ndufs4 ablation decreases synaptophysin expression in hippocampus

Subrata Kumar Shil, Yoshiteru Kagawa, Banlanjo Abdulaziz Umaru, Fumika Nanto-Hara, Hirofumi Miyazaki, Yui Yamamoto, Shuhei Kobayashi, Chitose Suzuki, Takaaki Abe, Yuji Owada

Sci Rep. 2021; 11: 10969. Published online 2021 May 26. doi: 10.1038/s41598-021-90127-4

PMCID:: PMC8155116

Article PDF–1.6M

Select item 793877014.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

Select item 752975215.

Progressive optic atrophy in a retinal ganglion cell-specific mouse model of complex I deficiency

Luyu Wang, Mikael Klingeborn, Amanda M. Travis, Ying Hao, Vadim Y. Arshavsky, Sidney M. Gospe, III

Sci Rep. 2020; 10: 16326. Published online 2020 Oct 1. doi: 10.1038/s41598-020-73353-0

PMCID:: PMC7529752

Article PDF–6.3M

Select item 741571816.

NAD+ regeneration rescues lifespan but not ataxia in a mouse model of brain mitochondrial complex I dysfunction

Gregory. S. McElroy, Colleen R. Reczek, Paul A. Reyfman, Divakar S. Mithal, Craig M. Horbinski, Navdeep S. Chandel

Cell Metab. Author manuscript; available in PMC 2021 Aug 4.

Published in final edited form as: Cell Metab. 2020 Aug 4; 32(2): 301–308.e6. Published online 2020 Jun 22. doi: 10.1016/j.cmet.2020.06.003

PMCID:: PMC7415718

Article PDF–1.3M

Select item 739771417.

Serine catabolism feeds NADH when respiration is impaired

Lifeng Yang, Juan Carlos Garcia Canaveras, Zihong Chen, Lin Wang, Lingfan Liang, Cholsoon Jang, Johannes A. Mayr, Zhaoyue Zhang, Jonathan M. Ghergurovich, Le Zhan, Shilpy Joshi, Zhixian Hu, Melanie R. McReynolds, Xiaoyang Su, Eileen White, Raphael J. Morscher, Joshua D. Rabinowitz

Cell Metab. Author manuscript; available in PMC 2021 Apr 7.

Published in final edited form as: Cell Metab. 2020 Apr 7; 31(4): 809–821.e6. Published online 2020 Mar 17. doi: 10.1016/j.cmet.2020.02.017

PMCID:: PMC7397714

Article PDF–2.5M

Select item 727350518.

Succinate Can Shuttle Reducing Power from the Hypoxic Retina to the O₂-Rich Pigment Epithelium

Celia M. Bisbach, Daniel T. Hass, Brian M. Robbings, Austin M. Rountree, Martin Sadilek, Ian R. Sweet, James B. Hurley

Cell Rep. Author manuscript; available in PMC 2020 Jun 5.

Published in final edited form as: Cell Rep. 2020 May 5; 31(5): 107606. doi: 10.1016/j.celrep.2020.107606

PMCID:: PMC7273505

Article PDF–1.7M

Select item 727214119.

Regional metabolic signatures in the Ndufs4(KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease

Simon C. Johnson, Ernst-Bernhard Kayser, Rebecca Bornstein, Julia Stokes, Alessandro Bitto, Kyung Yeon Park, Amanda Pan, Grace Sun, Daniel Raftery, Matt Kaeberlein, Margaret M Sedensky, Philip G Morgan

Mol Genet Metab. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: Mol Genet Metab. 2020 Jun; 130(2): 118–132. Published online 2020 Apr 3. doi: 10.1016/j.ymgme.2020.03.007

PMCID:: PMC7272141

Article PDF–3.0M

Select item 726682020.

Impaired mitochondrial complex I function as a candidate driver in the biological stress response and a concomitant stress-induced brain metabolic reprogramming in male mice

Tim L. Emmerzaal, Graeme Preston, Bram Geenen, Vivienne Verweij, Maximilian Wiesmann, Elisavet Vasileiou, Femke Grüter, Corné de Groot, Jeroen Schoorl, Renske de Veer, Monica Roelofs, Martijn Arts, Yara Hendriksen, Eva Klimars, Taraka R. Donti, Brett H. Graham, Eva Morava, Richard J. Rodenburg, Tamas Kozicz

Transl Psychiatry. 2020; 10: 176. Published online 2020 Jun 1. doi: 10.1038/s41398-020-0858-y

PMCID:: PMC7266820

Article PDF–2.0M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 78

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity