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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 98275292.

Regulatory T cells suppress CD4⁺ effector T cell activation by controlling protein synthesis

Lomon So, Kazushige Obata-Ninomiya, Alex Hu, Virginia S. Muir, Ayako Takamori, Jing Song, Jane H. Buckner, Ram Savan, Steven F. Ziegler

J Exp Med. 2023 Mar 6; 220(3): e20221676. Published online 2023 Jan 4. doi: 10.1084/jem.20221676

PMCID:: PMC9827529

Abstract Article PDF–5.2M

Select item 92026123.

Antigen presentation safeguards the integrity of the hematopoietic stem cell pool

Pablo Hernández-Malmierca, Dominik Vonficht, Alexandra Schnell, Hannah J. Uckelmann, Alina Bollhagen, Mohamed A.A. Mahmoud, Sophie-Luise Landua, Elise van der Salm, Christine L. Trautmann, Simon Raffel, Florian Grünschläger, Raphael Lutz, Michael Ghosh, Simon Renders, Nádia Correia, Elisa Donato, Karin O. Dixon, Christoph Hirche, Carolin Andresen, Claudia Robens, Paula S. Werner, Tobias Boch, David Eisel, Wolfram Osen, Franziska Pilz, Adriana Przybylla, Corinna Klein, Frank Buchholz, Michael D. Milsom, Marieke A.G. Essers, Stefan B. Eichmüller, Wolf-Karsten Hofmann, Daniel Nowak, Daniel Hübschmann, Michael Hundemer, Christian Thiede, Lars Bullinger, Carsten Müller-Tidow, Scott A. Armstrong, Andreas Trumpp, Vijay K. Kuchroo, Simon Haas

Cell Stem Cell. Author manuscript; available in PMC 2023 May 5.

Published in final edited form as: Cell Stem Cell. 2022 May 5; 29(5): 760–775.e10. doi: 10.1016/j.stem.2022.04.007

PMCID:: PMC9202612

Abstract Article PDF–2.2M

Select item 70172364.

STAT3 Inhibits CD103⁺ cDC1 Vaccine Efficacy in Murine Breast Cancer

Taylor T. Chrisikos, Yifan Zhou, Haiyan S. Li, Rachel L. Babcock, Xianxiu Wan, Bhakti Patel, Kathryn Newton, James J. Mancuso, Stephanie S. Watowich

Cancers (Basel) 2020 Jan; 12(1): 128. Published online 2020 Jan 4. doi: 10.3390/cancers12010128

PMCID:: PMC7017236

Abstract Article PDF–2.8M

Select item 67780805.

Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23

Lili Chen, Valentina Strohmeier, Zhengxiang He, Madhura Deshpande, Jovani Catalan-Dibene, Scott K. Durum, Thomas M. Moran, Thomas Kraus, Huabao Xiong, Jeremiah J. Faith, Chhinder P. Sodhi, David J. Hackam, Sergio A. Lira, Glaucia C. Furtado

Nat Commun. 2019; 10: 4517. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12540-8

PMCID:: PMC6778080

Abstract Article PDF–7.6M

Select item 66842666.

IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses

Rachel A Gottschalk, Michael G Dorrington, Bhaskar Dutta, Kathleen S Krauss, Andrew J Martins, Stefan Uderhardt, Waipan Chan, John S Tsang, Parizad Torabi-Parizi, Iain DC Fraser, Ronald N Germain

eLife. 2019; 8: e46836. Published online 2019 Aug 6. doi: 10.7554/eLife.46836

PMCID:: PMC6684266

Abstract Article PDF–1.0M

Select item 65554267.

Chronic lymphocytic leukemia derived interleukin-10 suppresses anti-tumor immunity

Sara S. Alhakeem, Mary K. McKenna, Karine Z. Oben, Sunil K. Noothi, Jacqueline R. Rivas, Gerhard C. Hildebrandt, Roger A. Fleischman, Vivek M. Rangnekar, Natarajan Muthusamy, Subbarao Bondada

J Immunol. Author manuscript; available in PMC 2019 Jun 15.

Published in final edited form as: J Immunol. 2018 Jun 15; 200(12): 4180–4189. Published online 2018 Apr 30. doi: 10.4049/jimmunol.1800241

PMCID:: PMC6555426

Abstract Article PDF–4.0M

Select item 65426498.

Blocking IL-10 receptor signaling ameliorates Mycobacterium tuberculosis infection during influenza-induced exacerbation

Sarah Ring, Lars Eggers, Jochen Behrends, Adam Wutkowski, Dominik Schwudke, Andrea Kröger, Alexandra Maximiliane Hierweger, Christoph Hölscher, Gülsah Gabriel, Bianca E. Schneider

JCI Insight. 2019 May 16; 4(10): e126533. Published online 2019 May 16. doi: 10.1172/jci.insight.126533

PMCID:: PMC6542649

Abstract Article PDF–3.6M

Select item 65313539.

Adaptive plasticity of IL-10⁺ and IL-35⁺ T_reg cells cooperatively promotes tumor T cell exhaustion

Deepali V. Sawant, Hiroshi Yano, Maria Chikina, Qianxia Zhang, Mengting Liao, Chang Liu, Derrick J Callahan, Zhe Sun, Tao Sun, Tracy Tabib, Arjun Pennathur, David B. Corry, James D. Luketich, Robert Lafyatis, Wei Chen, Amanda C. Poholek, Tullia C. Bruno, Creg J. Workman, Dario A.A. Vignali

Nat Immunol. Author manuscript; available in PMC 2019 Oct 1.

Published in final edited form as: Nat Immunol. 2019 Jun; 20(6): 724–735. Published online 2019 Apr 1. doi: 10.1038/s41590-019-0346-9

PMCID:: PMC6531353

Abstract Article PDF–3.6M

Select item 649704910.

Female-biased embryonic death from genomic instability-induced inflammation

Adrian J. McNairn, Chen-Hua Chuang, Jordana C. Bloom, Marsha D. Wallace, John C. Schimenti

Nature. Author manuscript; available in PMC 2019 Aug 20.

Published in final edited form as: Nature. 2019 Mar; 567(7746): 105–108. Published online 2019 Feb 20. doi: 10.1038/s41586-019-0936-6

PMCID:: PMC6497049

Abstract Article PDF–1018K

Select item 645951011.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 638531812.

STAT1 signaling shields T cells from NK cell-mediated cytotoxicity

Yu Hui Kang, Amlan Biswas, Michael Field, Scott B. Snapper

Nat Commun. 2019; 10: 912. Published online 2019 Feb 22. doi: 10.1038/s41467-019-08743-8

PMCID:: PMC6385318

Abstract Article PDF–1.8M

Select item 619284913.

Regulatory T cells promote macrophage efferocytosis during inflammation resolution

Jonathan D. Proto, Amanda C. Doran, Galina Gusarova, Arif Yurdagul, Jr., Erdi Sozen, Manikandan Subramanian, Mohammad N. Islam, Christina C. Rymond, Jasper Du, Jaime Hook, George Kuriakose, Jahar Bhattacharya, Ira Tabas

Immunity. Author manuscript; available in PMC 2019 Oct 16.

Published in final edited form as: Immunity. 2018 Sep 25 : S1074-7613(18)30335-2. Published online 2018 Sep 25. doi: 10.1016/j.immuni.2018.07.015

PMCID:: PMC6192849

Article PDF–967K

Select item 590616114.

Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells

Kristina S. Burrack, Matthew A. Huggins, Emily Taras, Philip Dougherty, Christine M. Henzler, Rendong Yang, Sarah Alter, Emily K. Jeng, Hing C. Wong, Martin Felices, Frank Cichocki, Jeffrey S. Miller, Geoffrey T. Hart, Aaron J. Johnson, Stephen C. Jameson, Sara E. Hamilton

Immunity. Author manuscript; available in PMC 2019 Apr 17.

Published in final edited form as: Immunity. 2018 Apr 17; 48(4): 760–772.e4. Published online 2018 Apr 3. doi: 10.1016/j.immuni.2018.03.012

PMCID:: PMC5906161

Abstract Article PDF–1.4M

Select item 563463715.

Re-evaluation of IL-10 signaling reveals novel insights on the contribution of the intracellular domain of the IL-10R2 chain

Ruud H. P. Wilbers, Debbie R. van Raaij, Lotte B. Westerhof, Jaap Bakker, Geert Smant, Arjen Schots

PLoS One. 2017; 12(10): e0186317. Published online 2017 Oct 10. doi: 10.1371/journal.pone.0186317

PMCID:: PMC5634637

Abstract Article PDF–5.5M

Select item 553192316.

Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor

Naresh S Redhu, Vasudevan Bakthavatchalu, Evan A Conaway, Dror S Shouval, Amy Tsou, Jeremy A Goettel, Amlan Biswas, Chuanwu Wang, Michael Field, Werner Muller, Andre Bleich, Ning Li, Georg K Gerber, Lynn Bry, James G Fox, Scott B Snapper, Bruce H Horwitz

eLife. 2017; 6: e27652. Published online 2017 Jul 5. doi: 10.7554/eLife.27652