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Items: 1 to 20 of 111

1.
Early establishment of chloride homeostasis in CRH neurons is altered by prenatal stress leading to fetal HPA axis dysregulation
Miho Watanabe, Adya Saran Sinha, Yohei Shinmyo, Atsuo Fukuda
Front Mol Neurosci. 2024; 17: 1373337. Published online 2024 Mar 21. doi: 10.3389/fnmol.2024.1373337
PMCID:
PMC10994000
AbstractArticlePDF–1.5M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
4.
Overexpression of neuronal K+–Cl− co-transporter enhances dendritic spine plasticity and motor learning
Kayo Nakamura, Andrew John Moorhouse, Dennis Lawrence Cheung, Kei Eto, Ikuko Takeda, Paul Wiers Rozenbroek, Junichi Nabekura
J Physiol Sci. 2019 May; 69(3): 453–463. Published online 2019 Feb 13. doi: 10.1007/s12576-018-00654-5
PMCID:
PMC10717839
AbstractArticlePDF–2.4M
5.
BDNF-TrkB signaling pathway-mediated microglial activation induces neuronal KCC2 downregulation contributing to dynamic allodynia following spared nerve injury
Zihan Hu, Xinren Yu, Pei Chen, Keyu Jin, Jing Zhou, Guoxiang Wang, Jiangning Yu, Tong Wu, Yulong Wang, Fuqing Lin, Tingting Zhang, Yun Wang, Xuan Zhao
Mol Pain. 2023; 19: 17448069231185439. Published online 2023 Aug 3. doi: 10.1177/17448069231185439
Correction in:
Mol Pain. 2024; 20: 17448069231222686.
PMCID:
PMC10402286
AbstractArticlePDF–2.4M
6.
KCC2 downregulation after sciatic nerve injury enhances motor function recovery
Dennis Lawrence Cheung, Takuya Toda, Madoka Narushima, Kei Eto, Chitoshi Takayama, Tatsuko Ooba, Hiroaki Wake, Andrew John Moorhouse, Junichi Nabekura
Sci Rep. 2023; 13: 7871. Published online 2023 May 15. doi: 10.1038/s41598-023-34701-y
PMCID:
PMC10185507
AbstractArticlePDF–3.4M
7.
Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development
Samu N Kurki, Pavel Uvarov, Alexey S Pospelov, Kalevi Trontti, Antje K Hübner, Rakenduvadhana Srinivasan, Masahiko Watanabe, Iiris Hovatta, Christian A Hübner, Kai Kaila, Mari A Virtanen
Cereb Cortex. 2023 May 15; 33(10): 5906–5923. Published online 2022 Dec 27. doi: 10.1093/cercor/bhac470
PMCID:
PMC10183754
AbstractArticlePDF–3.1M
8.
Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory
Anna Kreis, Farah Issa, Xavier Yerna, Caren Jabbour, Olivier Schakman, Marie de Clippele, Nicolas Tajeddine, Nathalie Pierrot, Jean-Noël Octave, Roberta Gualdani, Philippe Gailly
Front Mol Neurosci. 2023; 16: 1081657. Published online 2023 Apr 24. doi: 10.3389/fnmol.2023.1081657
PMCID:
PMC10164999
AbstractArticlePDF–4.7M
9.
Role of NKCC1 and KCC2 during hypoxia-induced neuronal swelling in the neonatal neocortex
Yusuke Takezawa, Rachel Langton, Samuel M. Baule, Miriam Bridget Zimmerman, Stephen Baek, Joseph Glykys
Neurobiol Dis. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: Neurobiol Dis. 2023 Mar; 178: 106013. Published online 2023 Jan 25. doi: 10.1016/j.nbd.2023.106013
PMCID:
PMC9945323
AbstractArticlePDF–2.3M
10.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
AbstractArticlePDF–5.3M
11.
Neonatal inflammation increases hippocampal KCC2 expression through methylation-mediated TGF-β1 downregulation leading to impaired hippocampal cognitive function and synaptic plasticity in adult mice
Jing Rong, Yang Yang, Min Liang, Haiquan Zhong, Yingchun Li, Yichao Zhu, Sha Sha, Lei Chen, Rong Zhou
J Neuroinflammation. 2023; 20: 15. Published online 2023 Jan 23. doi: 10.1186/s12974-023-02697-x
PMCID:
PMC9872321
AbstractArticlePDF–5.6M
12.
TGF-β2 Regulates Transcription of the K+/Cl− Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons
Anastasia Rigkou, Attila Magyar, Jan Manuel Speer, Eleni Roussa
Cells. 2022 Dec; 11(23): 3861. Published online 2022 Nov 30. doi: 10.3390/cells11233861
PMCID:
PMC9739967
AbstractArticlePDF–3.4M
13.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
14.
Loss of KCC2 in GABAergic Neurons Causes Seizures and an Imbalance of Cortical Interneurons
Kirill Zavalin, Anjana Hassan, Cary Fu, Eric Delpire, Andre H. Lagrange
Front Mol Neurosci. 2022; 15: 826427. Published online 2022 Mar 16. doi: 10.3389/fnmol.2022.826427
PMCID:
PMC8966887
AbstractArticlePDF–8.9M
15.
Disruption of KCC2 in Parvalbumin-Positive Interneurons Is Associated With a Decreased Seizure Threshold and a Progressive Loss of Parvalbumin-Positive Interneurons
Tanja Herrmann, Melanie Gerth, Ralf Dittmann, Daniel Pensold, Martin Ungelenk, Lutz Liebmann, Christian A. Hübner
Front Mol Neurosci. 2021; 14: 807090. Published online 2022 Feb 3. doi: 10.3389/fnmol.2021.807090
PMCID:
PMC8850922
AbstractArticlePDF–3.1M
16.
Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice
Aaron J. Barbour, Sara R. Nass, Yun K. Hahn, Kurt F. Hauser, Pamela E. Knapp
ASN Neuro. 2021 Jan-Dec; 13: 17590914211022089. Published online 2021 Aug 26. doi: 10.1177/17590914211022089
PMCID:
PMC8404672
AbstractArticlePDF–1.2M
17.
Structural changes in the extracellular loop 2 of the murine KCC2 potassium chloride cotransporter modulate ion transport
Anna-Maria Hartmann, Lifei Fu, Christine Ziegler, Michael Winklhofer, Hans Gerd Nothwang
J Biol Chem. 2021 Jan-Jun; 296: 100793. Published online 2021 May 18. doi: 10.1016/j.jbc.2021.100793
PMCID:
PMC8191313
AbstractArticlePDF–3.4M
18.
KCC2 Chloride Transport Contributes to the Termination of Ictal Epileptiform Activity
Volodymyr I. Dzhala, Kevin J. Staley
eNeuro. 2021 Mar-Apr; 8(2): ENEURO.0208-20.2020. Prepublished online 2020 Nov 25. Published online 2021 Mar 8. doi: 10.1523/ENEURO.0208-20.2020
PMCID:
PMC7986536
AbstractArticlePDF–3.6M
19.
KCC2 is required for the survival of mature neurons but not for their development
Georgina Kontou, Shu Fun Josephine Ng, Ross A. Cardarelli, Jack H. Howden, Catherine Choi, Qiu Ren, Miguel A. Rodriguez Santos, Christopher E. Bope, Jake S. Dengler, Matt R. Kelley, Paul A. Davies, Josef T. Kittler, Nicholas J. Brandon, Stephen J. Moss, Joshua L. Smalley
J Biol Chem. 2021 Jan-Jun; 296: 100364. Published online 2021 Feb 2. doi: 10.1016/j.jbc.2021.100364
PMCID:
PMC7949141
AbstractArticlePDF–4.2M
20.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M

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