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Items: 1 to 20 of 64

1.
Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells
Wataru Arai, Takumi Konno, Takayuki Kohno, Yuki Kodera, Mitsuhiro Tsujiwaki, Yuma Shindo, Hirofumi Chiba, Masahiro Miyajima, Yuji Sakuma, Atsushi Watanabe, Takashi Kojima
Oncotarget. 2023; 14: 261–275. Published online 2023 Mar 24. doi: 10.18632/oncotarget.27728
PMCID:
PMC10038356
AbstractArticlePDF–6.1M
2.
Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression
Rainelli Koumangoye, Parker Penny, Eric Delpire
Am J Physiol Cell Physiol. 2022 Oct 1; 323(4): C1251–C1263. Published online 2022 Aug 15. doi: 10.1152/ajpcell.00334.2022
PMCID:
PMC9576170
AbstractArticle
3.
AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability
Ashwinkumar Subramenium Ganapathy, Kushal Saha, Eric Suchanec, Vikash Singh, Aayush Verma, Gregory Yochum, Walter Koltun, Meghali Nighot, Thomas Ma, Prashant Nighot
Autophagy. 2022; 18(9): 2086–2103. Published online 2021 Dec 29. doi: 10.1080/15548627.2021.2016233
PMCID:
PMC9466623
AbstractArticlePDF–4.7M
4.
Elevation of Chemosensitivity of Lung Adenocarcinoma A549 Spheroid Cells by Claudin-2 Knockdown through Activation of Glucose Transport and Inhibition of Nrf2 Signal
Ayaka Ito, Haruka Nasako, Risa Akizuki, Yui Takashina, Hiroaki Eguchi, Toshiyuki Matsunaga, Yuta Yoshino, Satoshi Endo, Akira Ikari
Int J Mol Sci. 2021 Jun; 22(12): 6582. Published online 2021 Jun 19. doi: 10.3390/ijms22126582
PMCID:
PMC8235168
AbstractArticlePDF–2.4M
5.
Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern
Sébastien Tabariès, Matthew G. Annis, Anthoula Lazaris, Stephanie K. Petrillo, Jennifer Huxham, Amri Abdellatif, Vincent Palmieri, Jaclyn Chabot, Radia M. Johnson, Steven Van Laere, Cornelis Verhoef, Yasmina Hachem, Sara Yumeen, Nicholas Meti, Atilla Omeroglu, Gulbeyaz Altinel, Zu-Hua Gao, Alan S. L. Yu, Dirk J. Grünhagen, Peter Vermeulen, Peter Metrakos, Peter M. Siegel
Commun Biol. 2021; 4: 657. Published online 2021 Jun 2. doi: 10.1038/s42003-021-02189-9
PMCID:
PMC8172859
AbstractArticlePDF–9.3M
6.
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition
Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington
Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331
PMCID:
PMC8045932
AbstractArticlePDF–1.9M
7.
Down-Regulation of Claudin-2 Expression by Cyanidin-3-Glucoside Enhances Sensitivity to Anticancer Drugs in the Spheroid of Human Lung Adenocarcinoma A549 Cells
Hiroaki Eguchi, Haruka Matsunaga, Saki Onuma, Yuta Yoshino, Toshiyuki Matsunaga, Akira Ikari
Int J Mol Sci. 2021 Jan; 22(2): 499. Published online 2021 Jan 6. doi: 10.3390/ijms22020499
PMCID:
PMC7825397
AbstractArticlePDF–5.9M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
Claudin-2 deficiency associates with hypercalciuria in mice and human kidney stone disease
Joshua N. Curry, Matthew Saurette, Masomeh Askari, Lei Pei, Michael B. Filla, Megan R. Beggs, Peter S.N. Rowe, Timothy Fields, Andre J. Sommer, Chizu Tanikawa, Yoichiro Kamatani, Andrew P. Evan, Mehdi Totonchi, R. Todd Alexander, Koichi Matsuda, Alan S.L. Yu
J Clin Invest. 2020 Apr 1; 130(4): 1948–1960. Published online 2020 Mar 9. doi: 10.1172/JCI127750
PMCID:
PMC7108907
AbstractArticlePDF–7.0M
10.
Differential regulation of claudin-2 and claudin-15 expression in children and adults with malabsorptive disease
M. Lora D. M. Ong, Sunil Yeruva, Anne Sailer, Steven P. Nilsen, Jerrold R. Turner
Lab Invest. Author manuscript; available in PMC 2020 Apr 11.
Published in final edited form as: Lab Invest. 2020 Mar; 100(3): 483–490. Published online 2019 Oct 11. doi: 10.1038/s41374-019-0324-8
PMCID:
PMC7047618
AbstractArticlePDF–3.0M
11.
Claudin-2: Roles beyond Permeability Functions
Shruthi Venugopal, Shaista Anwer, Katalin Szászi
Int J Mol Sci. 2019 Nov; 20(22): 5655. Published online 2019 Nov 12. doi: 10.3390/ijms20225655
PMCID:
PMC6888627
AbstractArticlePDF–1.0M
12.
Caveolin 1 is Associated with Upregulated Claudin 2 in Necrotizing Enterocolitis
Guillermo Ares, Christie Buonpane, John Sincavage, Carrie Yuan, Douglas R. Wood, Catherine J. Hunter
Sci Rep. 2019; 9: 4982. Published online 2019 Mar 21. doi: 10.1038/s41598-019-41442-4
PMCID:
PMC6428816
AbstractArticlePDF–1.5M
13.
Afadin cooperates with Claudin-2 to promote breast cancer metastasis
Sébastien Tabariès, Alexander McNulty, Véronique Ouellet, Matthew G. Annis, Mireille Dessureault, Maude Vinette, Yasmina Hachem, Brennan Lavoie, Atilla Omeroglu, Hans-Georg Simon, Logan A. Walsh, Siker Kimbung, Ingrid Hedenfalk, Peter M. Siegel
Genes Dev. 2019 Feb 1; 33(3-4): 180–193. doi: 10.1101/gad.319194.118
PMCID:
PMC6362814
AbstractArticlePDF–8.2M
14.
Transcriptomic Landscape of Treatment—Naïve Ulcerative Colitis
Hagar Taman, Christopher G Fenton, Inga V Hensel, Endre Anderssen, Jon Florholmen, Ruth H Paulssen
J Crohns Colitis. 2018 Feb; 12(3): 327–336. Published online 2017 Oct 10. doi: 10.1093/ecco-jcc/jjx139
PMCID:
PMC6290885
AbstractArticlePDF–327K
15.
Lack of Vitamin D Receptor Leads to Hyperfunction of Claudin-2 in Intestinal Inflammatory Responses
Yong-guo Zhang, Rong Lu, Yinglin Xia, David Zhou, Elaine Petrof, Erika C Claud, Jun Sun
Inflamm Bowel Dis. 2019 Jan; 25(1): 97–110. Published online 2018 Oct 4. doi: 10.1093/ibd/izy292
PMCID:
PMC6290786
AbstractArticlePDF–1.0M
16.
T cell protein tyrosine phosphatase prevents STAT1 induction of claudin-2 expression in intestinal epithelial cells
Moorthy Krishnan, Declan F. McCole
Ann N Y Acad Sci. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Ann N Y Acad Sci. 2017 Oct; 1405(1): 116–130. Published online 2017 Aug 14. doi: 10.1111/nyas.13439
PMCID:
PMC5768570
AbstractArticlePDF–1.1M
17.
Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells
Sua Kim, Gheun-Ho Kim
PLoS One. 2017; 12(12): e0189221. Published online 2017 Dec 18. doi: 10.1371/journal.pone.0189221
PMCID:
PMC5734727
AbstractArticlePDF–2.5M
18.
Microbial-derived Butyrate Promotes Epithelial Barrier Function Through IL-10 Receptor-dependent Repression of Claudin-2
Leon Zheng, Caleb J. Kelly, Kayla D. Battista, Rachel Schaefer, Jordi M. Lanis, Erica E. Alexeev, Ruth X. Wang, Joseph C. Onyiah, Douglas J. Kominsky, Sean P. Colgan
J Immunol. Author manuscript; available in PMC 2018 Oct 15.
Published in final edited form as: J Immunol. 2017 Oct 15; 199(8): 2976–2984. Published online 2017 Sep 11. doi: 10.4049/jimmunol.1700105
PMCID:
PMC5636678
AbstractArticlePDF–1.1M
19.
Claudin‐2 is an independent negative prognostic factor in breast cancer and specifically predicts early liver recurrences
Siker Kimbung, Anikó Kovács, Pär-Ola Bendahl, Per Malmström, Mårten Fernö, Thomas Hatschek, Ingrid Hedenfalk
Mol Oncol. 2014 Feb; 8(1): 119–128. Published online 2013 Oct 14. doi: 10.1016/j.molonc.2013.10.002
PMCID:
PMC5528500
AbstractArticlePDF–1.2M
20.
High expression of Claudin-2 in esophageal carcinoma and precancerous lesions is significantly associated with the bile salt receptors VDR and TGR5
Sohaib Abu-Farsakh, Tongtong Wu, Amy Lalonde, Jun Sun, Zhongren Zhou
BMC Gastroenterol. 2017; 17: 33. Published online 2017 Feb 17. doi: 10.1186/s12876-017-0590-0
PMCID:
PMC5316202
AbstractArticlePDF–1.3M

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