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Select item 110214831.

Ferritin heavy chain supports stability and function of the regulatory T cell lineage

Qian Wu, Ana Rita Carlos, Faouzi Braza, Marie-Louise Bergman, Jamil Z Kitoko, Patricia Bastos-Amador, Eloy Cuadrado, Rui Martins, Bruna Sabino Oliveira, Vera C Martins, Brendon P Scicluna, Jonathan JM Landry, Ferris E Jung, Temitope W Ademolue, Mirko Peitzsch, Jose Almeida-Santos, Jessica Thompson, Silvia Cardoso, Pedro Ventura, Manon Slot, Stamatia Rontogianni, Vanessa Ribeiro, Vital Da Silva Domingues, Inês A Cabral, Sebastian Weis, Marco Groth, Cristina Ameneiro, Miguel Fidalgo, Fudi Wang, Jocelyne Demengeot, Derk Amsen, Miguel P Soares

EMBO J. 2024 Apr; 43(8): 1445–1483. Published online 2024 Mar 18. doi: 10.1038/s44318-024-00064-x

PMCID:: PMC11021483

Abstract Article PDF–6.1M

Select item 110103332.

FTH1 protects against osteoarthritis by MAPK pathway inhibition of extracellular matrix degradation

Zhikun Yuan, Lingfeng Yang, Yanhui Li, Xuming Li, Changgui Peng, Jianying Pan, Daozhang Cai

BMC Musculoskelet Disord. 2024; 25: 282. Published online 2024 Apr 12. doi: 10.1186/s12891-024-07411-3

PMCID:: PMC11010333

Abstract Article PDF–4.3M

Select item 107112533.

Distribution of ferritin complex in the adult brain and altered composition in neuroferritinopathy due to a novel variant in the ferritin heavy chain gene FTH1 (c.409_410del; p.H137Lfs*4)

Vincent Umathum, Axel Weber, Daniel Amsel, Ioannis Alexopoulos, Christina Becker, Angela Roth, Andreas Günther, Carmen Selignow, Nadja Ritschel, Anna Nishimura, Alexander Schaiter, Attila Németh, Peter F. M. van der Ven, Till Acker, Anne Schänzer

Brain Pathol. 2024 Jan; 34(1): e13176. Published online 2023 Jun 2. doi: 10.1111/bpa.13176

PMCID:: PMC10711253

Article PDF–3.7M

Select item 106588874.

FTH1 indicates poor prognosis and promotes metastasis in head and neck squamous cell carcinoma

Qingyun Liao, Jing Yang, Zhaoyi Lu, Qingshan Jiang, Yongqian Gong, Lijun Liu, Hong Peng, Qin Wang, Xin Zhang, Zhifeng Liu

PeerJ. 2023; 11: e16493. Published online 2023 Nov 17. doi: 10.7717/peerj.16493

PMCID:: PMC10658887

Abstract Article PDF–17M

Select item 105658765.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102080297.

LncRNA CACNA1G-AS1 up-regulates FTH1 to inhibit ferroptosis and promote malignant phenotypes in ovarian cancer cells

YANPING JIN, JIANPING QIU, XIUFANG LU, YAN MA, GUOWEI LI

Oncol Res. 2023; 31(2): 169–179. Published online 2023 Apr 10. doi: 10.32604/or.2023.027815

PMCID:: PMC10208029

Abstract Article PDF–9.5M

Select item 97725588.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 96543629.

Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration

Maddalena Di Sanzo, Flora Cozzolino, Anna Martina Battaglia, Ilenia Aversa, Vittoria Monaco, Alessandro Sacco, Flavia Biamonte, Camillo Palmieri, Francesca Procopio, Gianluca Santamaria, Francesco Ortuso, Piero Pucci, Maria Monti, Maria Concetta Faniello

Int J Mol Sci. 2022 Nov; 23(21): 12987. Published online 2022 Oct 26. doi: 10.3390/ijms232112987

PMCID:: PMC9654362

Abstract Article PDF–6.3M

Select item 962912110.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 950929311.

SARS-CoV-2-induced hypomethylation of the ferritin heavy chain (FTH1) gene underlies serum hyperferritinemia in severe COVID-19 patients

Jibran Sualeh Muhammad, Gehad ElGhazali, Jasmin Shafarin, Mohammad G. Mohammad, Ameera Abu-Qiyas, Mawieh Hamad

Biochem Biophys Res Commun. 2022 Nov 26; 631: 138–145. Published online 2022 Sep 25. doi: 10.1016/j.bbrc.2022.09.083

PMCID:: PMC9509293

Abstract Article PDF–1.0M

Select item 927928512.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 923661513.

Higher CSF Ferritin Heavy-Chain (Fth1) and Transferrin Predict Better Neurocognitive Performance in People with HIV

Harpreet Kaur, William S. Bush, Scott L. Letendre, Ronald J. Ellis, Robert K. Heaton, Stephanie M. Patton, James R. Connor, David C. Samuels, Donald R. Franklin, Todd Hulgan, Asha R. Kallianpur

Mol Neurobiol. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: Mol Neurobiol. 2021 Oct; 58(10): 4842–4855. Published online 2021 Jun 30. doi: 10.1007/s12035-021-02433-7

PMCID:: PMC9236615

Abstract Article PDF–1.1M

Select item 911973614.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 909784515.

TNFα‐induced abnormal activation of TNFR/NF‐κB/FTH1 in endometrium is involved in the pathogenesis of early spontaneous abortion

Yuting Wen, Meng Cheng, Lang Qin, Wenming Xu

J Cell Mol Med. 2022 May; 26(10): 2947–2958. Published online 2022 Apr 20. doi: 10.1111/jcmm.17308

PMCID:: PMC9097845

Abstract Article PDF–14M

Select item 883479216.

Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer’s, and Parkinson’s Diseases

Animesh Alexander Raha, Anwesha Biswas, James Henderson, Subhojit Chakraborty, Anthony Holland, Robert P. Friedland, Elizabeta Mukaetova-Ladinska, Shahid Zaman, Ruma Raha-Chowdhury

Int J Mol Sci. 2022 Feb; 23(3): 1060. Published online 2022 Jan 19. doi: 10.3390/ijms23031060