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Select item 106560201.

Dominant negative variants in KIF5B cause osteogenesis imperfecta via down regulation of mTOR signaling

Ronit Marom, Bo Zhang, Megan E. Washington, I-Wen Song, Lindsay C. Burrage, Vittoria C. Rossi, Ava S. Berrier, Anika Lindsey, Jacob Lesinski, Michael L. Nonet, Jian Chen, Dustin Baldridge, Gary A. Silverman, V. Reid Sutton, Jill A. Rosenfeld, Alyssa A. Tran, M. John Hicks, David R. Murdock, Hongzheng Dai, MaryAnn Weis, Shalini N. Jhangiani, Donna M. Muzny, Richard A. Gibbs, Richard Caswell, Carrie Pottinger, Deirdre Cilliers, Karen Stals, Undiagnosed Diseases Network, David Eyre, Deborah Krakow, Tim Schedl, Stephen C. Pak, Brendan H. Lee

PLoS Genet. 2023 Nov; 19(11): e1011005. Published online 2023 Nov 7. doi: 10.1371/journal.pgen.1011005

PMCID:: PMC10656020

Abstract Article PDF–3.1M

Select item 96038602.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 94819333.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 89477664.

Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration

Sahil H Shah, Lucio M Schiapparelli, Yuanhui Ma, Satoshi Yokota, Melissa Atkins, Xin Xia, Evan G Cameron, Thanh Huang, Sarah Saturday, Catalina B Sun, Cara Knasel, Seth Blackshaw, John R Yates, Hollis T Cline, Jeffrey L Goldberg

eLife. 2022; 11: e68148. Published online 2022 Mar 8. doi: 10.7554/eLife.68148

PMCID:: PMC8947766

Abstract Article PDF–6.3M

Select item 86945905.

Endosomal sorting drives the formation of axonal prion protein endoggresomes

Romain Chassefeyre, Tai Chaiamarit, Adriaan Verhelle, Sammy Weiser Novak, Leonardo R. Andrade, André D. G. Leitão, Uri Manor, Sandra E. Encalada

Sci Adv. 2021 Dec; 7(52): eabg3693. Published online 2021 Dec 22. doi: 10.1126/sciadv.abg3693

PMCID:: PMC8694590

Abstract Article PDF–13M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74159918.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 71566339.

Kinesin-1 regulates antigen cross-presentation through the scission of tubulations from early endosomes in dendritic cells

Meriem Belabed, François-Xavier Mauvais, Sophia Maschalidi, Mathieu Kurowska, Nicolas Goudin, Jian-Dong Huang, Alain Fischer, Geneviève de Saint Basile, Peter van Endert, Fernando E. Sepulveda, Gaël Ménasché

Nat Commun. 2020; 11: 1817. Published online 2020 Apr 14. doi: 10.1038/s41467-020-15692-0

PMCID:: PMC7156633

Abstract Article PDF–3.3M

Select item 704167610.

Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain

Min Lee, Yen-Chen Liu, Chen Chen, Chi-Huan Lu, Shao-Tzu Lu, Tzyy-Nan Huang, Meng-Tsung Hsu, Yi-Ping Hsueh, Pei-Lin Cheng

J Cell Biol. 2020 Feb 3; 219(2): e201903033. Published online 2020 Jan 7. doi: 10.1083/jcb.201903033

PMCID:: PMC7041676

Abstract Article PDF–5.4M

Select item 702836811.

Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

Junjun Zhao, Albert Hiu Ka Fok, Ruolin Fan, Pui-Yi Kwan, Hei-Lok Chan, Louisa Hoi-Ying Lo, Ying-Shing Chan, Wing-Ho Yung, Jiandong Huang, Cora Sau Wan Lai, Kwok-On Lai

eLife. 2020; 9: e53456. Published online 2020 Jan 21. doi: 10.7554/eLife.53456

PMCID:: PMC7028368

Abstract Article PDF–5.0M

Select item 677294812.

KIF5C, a Novel Neuronal Kinesin Enriched in Motor Neurons

Yoshimitsu Kanai, Yasushi Okada, Yosuke Tanaka, Akihiro Harada, Sumio Terada, Nobutaka Hirokawa

J Neurosci. 2000 Sep 1; 20(17): 6374–6384. doi: 10.1523/JNEUROSCI.20-17-06374.2000

PMCID:: PMC6772948

Abstract Article PDF–1.6M

Select item 674078013.

Alzheimer's Presenilin 1 Mutations Impair Kinesin-Based Axonal Transport

Gustavo Pigino, Gerardo Morfini, Alejandra Pelsman, Mark P. Mattson, Scott T. Brady, Jorge Busciglio

J Neurosci. 2003 Jun 1; 23(11): 4499–4508. doi: 10.1523/JNEUROSCI.23-11-04499.2003

PMCID:: PMC6740780

Abstract Article PDF–383K

Select item 672608414.

Axonal Transport, Amyloid Precursor Protein, Kinesin-1, and the Processing Apparatus: Revisited

Orly Lazarov, Gerardo A. Morfini, Edward B. Lee, Mohamed H. Farah, Anita Szodorai, Scott R. DeBoer, Vassilis E. Koliatsos, Stefan Kins, Virginia M.-Y. Lee, Philip C. Wong, Donald L. Price, Scott T. Brady, Sangram S. Sisodia

J Neurosci. 2005 Mar 2; 25(9): 2386–2395. doi: 10.1523/JNEUROSCI.3089-04.2005

PMCID:: PMC6726084

Abstract Article PDF–497K

Select item 626277715.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 615841916.

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons

Grayson DuRaine, Todd W. Wisner, Paul Howard, David C. Johnson

J Virol. 2018 Oct 15; 92(20): e01269-18. Prepublished online 2018 Aug 1. Published online 2018 Sep 26. doi: 10.1128/JVI.01269-18

PMCID:: PMC6158419

Abstract Article PDF–1.5M

Select item 615546217.

Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration

Alban Latremoliere, Long Cheng, Michelle DeLisle, Chen Wu, Sheena Chew, Elizabeth B. Hutchinson, Andrew Sheridan, Chloe Alexandre, Frederic Latremoliere, Shu-Hsien Sheu, Sara Golidy, Takao Omura, Eric A. Huebner, Yanjie Fan, Mary C. Whitman, Elaine Nguyen, Crystal Hermawan, Carlo Pierpaoli, Max A. Tischfield, Clifford J. Woolf, Elizabeth C. Engle

Cell Rep. Author manuscript; available in PMC 2018 Sep 25.

Published in final edited form as: Cell Rep. 2018 Aug 14; 24(7): 1865–1879.e9. doi: 10.1016/j.celrep.2018.07.029

PMCID:: PMC6155462

Abstract Article PDF–4.9M

Select item 603620018.

Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes

Estifanos N. Habtemichael, Don T. Li, Abel Alcázar-Román, Xavier O. Westergaard, Muyi Li, Max C. Petersen, Hanbing Li, Stephen G. DeVries, Eric Li, Omar Julca-Zevallos, Joseph S. Wolenski, Jonathan S. Bogan

J Biol Chem. 2018 Jul 6; 293(27): 10466–10486. Published online 2018 May 17. doi: 10.1074/jbc.RA118.003021

PMCID:: PMC6036200

Abstract Article PDF–4.2M

Select item 572712119.

Ferric Chelate Reductase 1 Like Protein (FRRS1L) Associates with Dynein Vesicles and Regulates Glutamatergic Synaptic Transmission

Wenyan Han, Huiqing Wang, Jun Li, Shizhong Zhang, Wei Lu

Front Mol Neurosci. 2017; 10: 402. Published online 2017 Dec 8. doi: 10.3389/fnmol.2017.00402

PMCID:: PMC5727121

Abstract Article PDF–3.1M

Select item 566320120.

Binding of PLD2-generated phosphatidic acid to KIF5B promotes MT1-MMP surface trafficking and lung metastasis of mouse breast cancer cells

Ziqing Wang, Feng Zhang, Jingquan He, Ping Wu, Li Wei Rachel Tay, Ming Cai, Weiqi Nian, Yuanyuan Weng, Li Qin, Jeffrey T Chang, Laura B McIntire, Gilbert Di Paolo, Jianming Xu, Junmin Peng, Guangwei Du

Dev Cell. Author manuscript; available in PMC 2018 Oct 23.

Published in final edited form as: Dev Cell. 2017 Oct 23; 43(2): 186–197.e7. Published online 2017 Oct 12. doi: 10.1016/j.devcel.2017.09.012

PMCID:: PMC5663201

Abstract Article PDF–2.2M

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