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Items: 1 to 20 of 122

1.
FUS reads histone H3K36me3 to regulate alternative polyadenylation
Junqi Jia, Haonan Fan, Xinyi Wan, Yuan Fang, Zhuoning Li, Yin Tang, Yanjun Zhang, Jun Huang, Dong Fang
Nucleic Acids Res. 2024 Jun 10; 52(10): 5549–5571. Published online 2024 Mar 18. doi: 10.1093/nar/gkae184
PMCID:
PMC11162772
AbstractArticlePDF–2.7M
2.
Pigpen, a nuclear coiled body component protein, is involved in angiogenesis
Tomoko Yoshida, Yasufumi Sato, Ikuo Morita, Mayumi Abe
Cancer Sci. 2010 May; 101(5): 1170–1176. Published online 2010 Jan 12. doi: 10.1111/j.1349-7006.2010.01494.x
PMCID:
PMC11159043
AbstractArticlePDF–924K
3.
The crucial role of HFM1 in regulating FUS ubiquitination and localization for oocyte meiosis prophase I progression in mice
Chenyi Zhong, Huiyuan Wang, Xiong Yuan, Yuheng He, Jing Cong, Rui Yang, Wenjie Ma, Li Gao, Chao Gao, Yugui Cui, Jie Wu, Rongrong Tan, Danhua Pu
Biol Res. 2024; 57: 36. Published online 2024 May 31. doi: 10.1186/s40659-024-00518-w
PMCID:
PMC11140966
AbstractArticlePDF–7.5M
4.
Cytoplasmic retention of the DNA/RNA-binding protein FUS ameliorates organ fibrosis in mice
Manuel Chiusa, Youngmin A. Lee, Ming-Zhi Zhang, Raymond C. Harris, Taylor Sherrill, Volkhard Lindner, Craig R. Brooks, Gang Yu, Agnes B. Fogo, Charles R. Flynn, Jozef Zienkiewicz, Jacek Hawiger, Roy Zent, Ambra Pozzi
J Clin Invest. 2024 Mar 15; 134(6): e175158. Published online 2024 Mar 15. doi: 10.1172/JCI175158
PMCID:
PMC10940094
AbstractArticlePDF–29M
5.
FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease
Manohar Kodavati, Haibo Wang, Wenting Guo, Joy Mitra, Pavana M. Hegde, Vincent Provasek, Vikas H. Maloji Rao, Indira Vedula, Aijun Zhang, Sankar Mitra, Alan E. Tomkinson, Dale J. Hamilton, Ludo Van Den Bosch, Muralidhar L. Hegde
Nat Commun. 2024; 15: 2156. Published online 2024 Mar 9. doi: 10.1038/s41467-024-45978-6
PMCID:
PMC10925063
AbstractArticlePDF–3.1M
6.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
7.
Mutation in the FUS nuclear localisation signal domain causes neurodevelopmental and systemic metabolic alterations
Zeinab Ali, Juan M. Godoy-Corchuelo, Aurea B. Martins-Bach, Irene Garcia-Toledo, Luis C. Fernández-Beltrán, Remya R. Nair, Shoshana Spring, Brian J. Nieman, Irene Jimenez-Coca, Rasneer S. Bains, Hamish Forrest, Jason P. Lerch, Karla L. Miller, Elizabeth M. C. Fisher, Thomas J. Cunningham, Silvia Corrochano
Dis Model Mech. 2023 Oct 1; 16(10): dmm050200. Published online 2023 Oct 23. doi: 10.1242/dmm.050200
PMCID:
PMC10642611
AbstractArticle
8.
FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons
Wan Yun Ho, Li-Ling Chak, Jin-Hui Hor, Fujia Liu, Sandra Diaz-Garcia, Jer-Cherng Chang, Emma Sanford, Maria J. Rodriguez, Durgadevi Alagappan, Su Min Lim, Yik-Lam Cho, Yuji Shimizu, Alfred Xuyang Sun, Sheue-Houy Tyan, Edward Koo, Seung Hyun Kim, John Ravits, Shi-Yan Ng, Katsutomo Okamura, Shuo-Chien Ling
iScience. 2023 Nov 17; 26(11): 108152. Published online 2023 Oct 6. doi: 10.1016/j.isci.2023.108152
PMCID:
PMC10618709
AbstractArticlePDF–6.0M
9.
CircZNF367 promotes osteoclast differentiation and osteoporosis by interacting with FUS to maintain CRY2 mRNA stability
Mingsi Deng, Zhengguang Wang, Jia Luo, Heng Cao, Yong Li, Liangjian Chen, Gengyan Liu
J Orthop Surg Res. 2023; 18: 492. Published online 2023 Jul 11. doi: 10.1186/s13018-023-03955-7
PMCID:
PMC10334599
AbstractArticlePDF–9.2M
10.
Clonally expanded CD8 T cells characterize Amyotrophic Lateral Sclerosis 4
Laura Campisi, Shahab Chizari, Jessica S.Y. Ho, Anastasia Gromova, Frederick J. Arnold, Lorena Mosca, Xueyan Mei, Yesai Fstkchyan, Denis Torre, Cindy Beharry, Marta Garcia-forn, Miguel Jiménez Alcázar, Vladislav A. Korobeynikov, Jack Prazich, Zahi A. Fayad, Marcus M. Seldin, Silvia de Rubeis, Craig L. Bennett, Lyle W. Ostrow, Christian Lunetta, Massimo Squatrito, Minji Byun, Neil A. Shneider, Ning Jiang, Albert R. La Spada, Ivan Marazzi
Nature. Author manuscript; available in PMC 2023 Apr 11.
Published in final edited form as: Nature. 2022 Jun; 606(7916): 945–952. Published online 2022 Jun 22. doi: 10.1038/s41586-022-04844-5
Correction in:
Nature. 2022 Aug; 608(7924): E34.
PMCID:
PMC10089623
AbstractArticlePDF–7.6M
11.
The RNA-binding protein FUS/TLS interacts with SPO11 and PRDM9 and localize at meiotic recombination hotspots
Teresa Giannattasio, Erika Testa, Ramona Palombo, Lidia Chellini, Flavia Franceschini, Álvaro Crevenna, Petko M. Petkov, Maria Paola Paronetto, Marco Barchi
Cell Mol Life Sci. 2023 Apr; 80(4): 107. Published online 2023 Mar 26. doi: 10.1007/s00018-023-04744-5
PMCID:
PMC10040399
AbstractArticlePDF–2.0M
12.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
13.
Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis
Vladislav A. Korobeynikov, Alexander K. Lyashchenko, Beatriz Blanco-Redondo, Paymaan Jafar-Nejad, Neil A. Shneider
Nat Med. 2022; 28(1): 104–116. Published online 2022 Jan 24. doi: 10.1038/s41591-021-01615-z
PMCID:
PMC8799464
AbstractArticlePDF–8.7M
14.
The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins
Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo
BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y
PMCID:
PMC8744257
AbstractArticlePDF–6.0M
15.
FUS driven circCNOT6L biogenesis in mouse and human spermatozoa supports zygote development
Teresa Chioccarelli, Geppino Falco, Donato Cappetta, Antonella De Angelis, Luca Roberto, Martina Addeo, Marco Ragusa, Davide Barbagallo, Liberato Berrino, Michele Purrello, Concetta Ambrosino, Gilda Cobellis, Riccardo Pierantoni, Rosanna Chianese, Francesco Manfrevola
Cell Mol Life Sci. 2022 Jan; 79(1): 50. Published online 2021 Dec 22. doi: 10.1007/s00018-021-04054-8
PMCID:
PMC8739325
AbstractArticlePDF–2.5M
16.
Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models
Anny Devoy, Georgia Price, Francesca De Giorgio, Rosie Bunton-Stasyshyn, David Thompson, Samanta Gasco, Alasdair Allan, Gemma F. Codner, Remya R. Nair, Charlotte Tibbit, Ross McLeod, Zeinab Ali, Judith Noda, Alessandro Marrero-Gagliardi, José M. Brito-Armas, Chloe Williams, Muhammet M. Öztürk, Michelle Simon, Edward O'Neill, Sam Bryce-Smith, Jackie Harrison, Gemma Atkins, Silvia Corrochano, Michelle Stewart, Jonathan D. Gilthorpe, Lydia Teboul, Abraham Acevedo-Arozena, Elizabeth M.C. Fisher, Thomas J. Cunningham
iScience. 2021 Dec 17; 24(12): 103463. Published online 2021 Nov 15. doi: 10.1016/j.isci.2021.103463
Correction in:
iScience. 2022 Apr 15; 25(4): 103999.
PMCID:
PMC8710557
AbstractArticlePDF–6.0M
17.
circ-Grm1 promotes pulmonary artery smooth muscle cell proliferation and migration via suppression of GRM1 expression by FUS
Shijing Sun, Qingyu Kong, Zhifeng Cai, Minmin Wang, Haizhao Zhao, Cuifen Zhao
Int J Mol Med. 2021 Nov; 48(5): 202. Published online 2021 Sep 16. doi: 10.3892/ijmm.2021.5035
PMCID:
PMC8480385
AbstractArticlePDF–8.7M
18.
Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation
Inmaculada Sanjuan-Ruiz, Noé Govea-Perez, Melissa McAlonis-Downes, Stéphane Dieterle, Salim Megat, Sylvie Dirrig-Grosch, Gina Picchiarelli, Diana Piol, Qiang Zhu, Brian Myers, Chao-Zong Lee, Don W Cleveland, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Luc Dupuis
Mol Neurodegener. 2021; 16: 61. Published online 2021 Sep 6. doi: 10.1186/s13024-021-00477-w
PMCID:
PMC8419956
AbstractArticlePDF–4.0M
19.
ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity
Maria Giovanna Garone, Nicol Birsa, Maria Rosito, Federico Salaris, Michela Mochi, Valeria de Turris, Remya R. Nair, Thomas J. Cunningham, Elizabeth M. C. Fisher, Mariangela Morlando, Pietro Fratta, Alessandro Rosa
Commun Biol. 2021; 4: 1025. Published online 2021 Sep 1. doi: 10.1038/s42003-021-02538-8
PMCID:
PMC8410767
AbstractArticlePDF–4.9M
20.
FUS regulates autophagy by mediating the transcription of genes critical to the autophagosome formation
Alexandra Arenas, Lisha Kuang, Jiayu Zhang, Meagan S. Kingren, Haining Zhu
J Neurochem. Author manuscript; available in PMC 2022 May 1.
Published in final edited form as: J Neurochem. 2021 May; 157(3): 752–763. Published online 2021 Jan 18. doi: 10.1111/jnc.15281
PMCID:
PMC8364620
AbstractArticlePDF–1.2M

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