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Items: 1 to 20 of 193

1.
Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy
Wenjuan Wu, Hongxia Jia, Song Chen, Xinran Ma, Shuai Zhou, Lingxiao Qiu, Xinhui Wu, Ping Li, Heying Chu, Guojun Zhang
Mol Med. 2024; 30: 72. Published online 2024 May 31. doi: 10.1186/s10020-024-00843-6
PMCID:
PMC11143656
AbstractArticlePDF–8.8M
2.
Pink1 deficiency enhances neurological deficits and inflammatory responses after intracerebral hemorrhage in mice
Jingchen Li, Jianliang Li, Erkun Guo, Yuanyu Wang, Ming Yang, Haoran Huo, Yunpeng Shi, Lin Zhao
Neurotherapeutics. 2024 Mar; 21(2): e00317. Published online 2024 Jan 23. doi: 10.1016/j.neurot.2024.e00317
PMCID:
PMC10963940
AbstractArticlePDF–1.5M
3.
Insulin signalling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons
J. Tabitha Hees, Simone Wanderoy, Jana Lindner, Marlena Helms, Hariharan Murali Mahadevan, Angelika B. Harbauer
Nat Metab. 2024; 6(3): 514–530. Published online 2024 Mar 19. doi: 10.1038/s42255-024-01007-w
PMCID:
PMC10963278
AbstractArticlePDF–15M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy
Fangfang Wang, Juan Bai, Xin Zhang, Dali Wang, Xin Zhang, Jingwen Xue, Haoyang Chen, Shuxiang Wang, Baojin Chi, Jing Li, Xiaoru Ma
J Diabetes Investig. 2024 Mar; 15(3): 288–299. Published online 2023 Nov 28. doi: 10.1111/jdi.14113
PMCID:
PMC10906015
AbstractArticlePDF–3.8M
6.
PINK1 restrains periodontitis-induced bone loss by preventing osteoclast mitophagy impairment
Ji Sun Jang, Seo Jin Hong, Shenzheng Mo, Min Kyung Kim, Yong-Gun Kim, Youngkyun Lee, Hong-Hee Kim
Redox Biol. 2024 Feb; 69: 103023. Published online 2023 Dec 30. doi: 10.1016/j.redox.2023.103023
PMCID:
PMC10789640
AbstractArticlePDF–11M
7.
Blockade of Hepatocyte PCSK9 Ameliorates Hepatic Ischemia-Reperfusion Injury by Promoting Pink1-Parkin–Mediated Mitophagy
Yu Zhang, Ziyi Wang, Chenyang Jia, Wenjie Yu, Xiangdong Li, Nan Xia, Huiling Nie, Likalamu Pascalia Wikana, Minhao Chen, Yong Ni, Sheng Han, Liyong Pu
Cell Mol Gastroenterol Hepatol. 2024; 17(1): 149–169. Published online 2023 Sep 16. doi: 10.1016/j.jcmgh.2023.09.004
PMCID:
PMC10696400
AbstractArticlePDF–13M
8.
Role of Pink1-mediated mitophagy in adenomyosis
Minmin Chen, Wei Wang, Xianyun Fu, Yongli Yi, Kun Wang, Meiling Wang
PeerJ. 2023; 11: e16497. Published online 2023 Nov 30. doi: 10.7717/peerj.16497
PMCID:
PMC10693823
AbstractArticlePDF–13M
9.
PINK1-PTEN axis promotes metastasis and chemoresistance in ovarian cancer via non-canonical pathway
Fang Zheng, Jiamin Zhong, Kelie Chen, Yu Shi, Fang Wang, Shengchao Wang, Song Tang, Xiaoyu Yuan, Zhangjin Shen, Sangsang Tang, Dajing Xia, Yihua Wu, Weiguo Lu
J Exp Clin Cancer Res. 2023; 42: 295. Published online 2023 Nov 9. doi: 10.1186/s13046-023-02823-w
PMCID:
PMC10633943
AbstractArticlePDF–14M
10.
PTEN-induced kinase 1 exerts protective effects in diabetic kidney disease by attenuating mitochondrial dysfunction and necroptosis
Min-Ji Sung, Hyun-Ju An, Min Heui Ha, Seon Hwa Park, Hye Yun Jeong, Jihyun Baek, Sang Ho Lee, Yu Ho Lee, So-Young Lee
Int J Biol Sci. 2023; 19(16): 5145–5159. Published online 2023 Oct 2. doi: 10.7150/ijbs.83906
PMCID:
PMC10620829
AbstractArticlePDF–7.4M
11.
C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagy
Hui Zhang, Chan Li, Qingyang Liu, Jingmei Li, Hao Wu, Rui Xu, Yidan Sun, Ming Cheng, Xiaoe Zhao, Menghao Pan, Qiang Wei, Baohua Ma
eLife. 2023; 12: RP88523. Published online 2023 Oct 20. doi: 10.7554/eLife.88523
PMCID:
PMC10588981
AbstractArticlePDF–9.3M
12.
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis
Enrico Radaelli, Charles-Antoine Assenmacher, Jillian Verrelle, Esha Banerjee, Florence Manero, Salim Khiati, Anais Girona, Guillermo Lopez-Lluch, Placido Navas, Marco Spinazzi
eLife. 2023; 12: e84710. Published online 2023 Jul 28. doi: 10.7554/eLife.84710
PMCID:
PMC10519710
AbstractArticlePDF–23M
13.
CERS6-derived ceramides aggravate kidney fibrosis by inhibiting PINK1-mediated mitophagy in diabetic kidney disease
Xiangyu Wang, Minkai Song, Xiaomin Li, Cailin Su, Yanlin Yang, Kai Wang, Cuiting Liu, Zongji Zheng, Yijie Jia, Shijing Ren, Wenhui Dong, Jiaqi Chen, Ting Wang, Lerong Liu, Meiping Guan, Chao Zhang, Yaoming Xue
Am J Physiol Cell Physiol. 2023 Aug 1; 325(2): C538–C549. Published online 2023 Jul 17. doi: 10.1152/ajpcell.00144.2023
PMCID:
PMC10511179
AbstractArticle
14.
Alpha‐synuclein‐associated changes in PINK1‐PRKN‐mediated mitophagy are disease context dependent
Xu Hou, Taylor Hsuan‐Yu Chen, Shunsuke Koga, Jenny M. Bredenberg, Ayman H. Faroqi, Marion Delenclos, Guojun Bu, Zbigniew K. Wszolek, Jonathan A. Carr, Owen A. Ross, Pamela J. McLean, Melissa E. Murray, Dennis W. Dickson, Fabienne C. Fiesel, Wolfdieter Springer
Brain Pathol. 2023 Sep; 33(5): e13175. Published online 2023 May 31. doi: 10.1111/bpa.13175
PMCID:
PMC10467041
AbstractArticlePDF–2.9M
15.
PTEN‐induced kinase 1 is associated with renal aging, via the cGAS‐STING pathway
Min Heui Ha, Man S. Kim, Hyun‐Ju An, Min‐Ji Sung, Yu Ho Lee, Dong‐Ho Yang, Sang Hyun Jung, Jihyun Baek, Yueun Choi, Deanne M. Taylor, Yuanchao Zhang, So‐Young Lee, Hye Yun Jeong
Aging Cell. 2023 Jul; 22(7): e13865. Published online 2023 May 15. doi: 10.1111/acel.13865
PMCID:
PMC10352563
AbstractArticlePDF–11M
16.
Autophagy prevents early proinflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen burden in macrophages
Rachel L. Kinsella, Jacqueline M. Kimmey, Asya Smirnov, Reilly Woodson, Margaret R. Gaggioli, Sthefany M. Chavez, Darren Kreamalmeyer, Christina L. Stallings
PLoS Biol. 2023 Jun; 21(6): e3002159. Published online 2023 Jun 15. doi: 10.1371/journal.pbio.3002159
PMCID:
PMC10306192
AbstractArticlePDF–1.8M
17.
PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates
Hideaki Matsui, Roberto Gavinio, Takeshi Asano, Norihito Uemura, Hidefumi Ito, Yoshihito Taniguchi, Yoshito Kobayashi, Takakuni Maki, Jie Shen, Shunichi Takeda, Kengo Uemura, Hodaka Yamakado, Ryosuke Takahashi
Hum Mol Genet. 2013 Jun 15; 22(12): 2423–2434. Published online 2013 Feb 27. doi: 10.1093/hmg/ddt095
PMCID:
PMC10259650
AbstractArticlePDF–785K
18.
PINK1 protects against dendritic cell dysfunction during sepsis through the regulation of mitochondrial quality control
You Wu, Longwang Chen, Zhimin Qiu, Xijing Zhang, Guangju Zhao, Zhongqiu Lu
Mol Med. 2023; 29: 25. Published online 2023 Feb 21. doi: 10.1186/s10020-023-00618-5
PMCID:
PMC9945621
AbstractArticlePDF–8.5M
19.
PINK1/Parkin-mediated mitophagy inhibits osteoblast apoptosis induced by advanced oxidation protein products
Wei Li, Wang-Sheng Jiang, Ya-Ru Su, Ke-Wu Tu, Lin Zou, Cong-Rui Liao, Qian Wu, Zi-Han Wang, Zhao-Ming Zhong, Jian-Ting Chen, Si-Yuan Zhu
Cell Death Dis. 2023 Feb; 14(2): 88. Published online 2023 Feb 7. doi: 10.1038/s41419-023-05595-5
PMCID:
PMC9905061
AbstractArticlePDF–7.4M
20.
Protective Effect of Electroacupuncture on the Barrier Function of Intestinal Injury in Endotoxemia through HO-1/PINK1 Pathway-Mediated Mitochondrial Dynamics Regulation
Yuan Zhang, Zhenzhen Meng, Lina Wu, Xiuyun Liu, Chenxu Guo, Jianbo Yu, Dong Ming, Shuan Dong, Yingya Cao, Xianhong Jiang
Oxid Med Cell Longev. 2023; 2023: 1464853. Published online 2023 Jan 7. doi: 10.1155/2023/1464853
PMCID:
PMC9840552
AbstractArticlePDF–2.7M

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