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Select item 107417821.

The Role of Sphingosine-1-Phosphate Receptor 2 in Mouse Retina Light Responses

Abhishek P. Shrestha, Megan Stiles, Richard C. Grambergs, Johane M. Boff, Saivikram Madireddy, Koushik Mondal, Rhea Rajmanna, Hunter Porter, David M. Sherry, Richard L. Proia, Thirumalini Vaithianathan, Nawajes Mandal

Biomolecules. 2023 Dec; 13(12): 1691. Published online 2023 Nov 23. doi: 10.3390/biom13121691

PMCID:: PMC10741782

Abstract Article PDF–4.1M

Select item 99674742.

Inhibition of Sphingosine-1-Phosphate Receptor 2 by JTE013 Enhanced Alveolar Bone Regeneration by Promoting Angiogenesis

William Lory, Bridgette Wellslager, Chao Sun, Özlem Yilmaz, Hong Yu

Int J Mol Sci. 2023 Feb; 24(4): 3401. Published online 2023 Feb 8. doi: 10.3390/ijms24043401

PMCID:: PMC9967474

Abstract Article PDF–2.6M

Select item 99066213.

Opposing Roles of Sphingosine 1-Phosphate Receptors 1 and 2 in Fat Deposition and Glucose Tolerance in Obese Male Mice

Motochika Asano, Kazuo Kajita, Masayuki Fuwa, Toshiko Kajita, Ichiro Mori, Noriyuki Akahoshi, Isao Ishii, Hiroyuki Morita

Endocrinology. 2023 Mar; 164(3): bqad019. Published online 2023 Jan 24. doi: 10.1210/endocr/bqad019

PMCID:: PMC9906621

Abstract Article

Select item 98012304.

Sphingosine 1-phosphate receptor 2 is central to maintaining epidermal barrier homeostasis

Satomi Igawa, Ayaka Ohzono, Phoebe Pham, Zhenping Wang, Teruaki Nakatsuji, Tatsuya Dokoshi, Anna Di Nardo

J Invest Dermatol. Author manuscript; available in PMC 2022 Dec 30.

Published in final edited form as: J Invest Dermatol. 2021 May; 141(5): 1188–1197.e5. Published online 2020 Nov 14. doi: 10.1016/j.jid.2020.09.026

PMCID:: PMC9801230

Abstract Article PDF–1.5M

Select item 95640715.

Sphingosine 1-phosphate receptor 2 mediated early stages of pancreatic and systemic inflammatory responses via NF-kappa B activation in acute pancreatitis

Jing Yang, Xujiao Tang, Baiqiang Li, Jinsong Shi

Cell Commun Signal. 2022; 20: 157. Published online 2022 Oct 13. doi: 10.1186/s12964-022-00971-8

PMCID:: PMC9564071

Abstract Article PDF–4.9M

Select item 94706556.

Sphingosine 1-Phoshpate Receptors are Located in Synapses and Control Spontaneous Activity of Mouse Neurons in Culture

Cecilia Skoug, Isak Martinsson, Gunnar K. Gouras, Anja Meissner, João M. N. Duarte

Neurochem Res. 2022; 47(10): 3114–3125. Published online 2022 Jul 4. doi: 10.1007/s11064-022-03664-3

PMCID:: PMC9470655

Abstract Article PDF–3.7M

Select item 92760267.

The function of Sphingosine-1-phosphate receptor 2 (S1PR2) in maintaining intestinal barrier and inducing ulcerative colitis

Tanzhou Chen, Kaier Gu, Ruoyang Lin, Yang Liu, Yunfeng Shan

Bioengineered. 2022; 13(5): 13703–13717. Published online 2022 Jun 15. doi: 10.1080/21655979.2022.2076500

PMCID:: PMC9276026

Abstract Article PDF–6.0M

Select item 92747368.

Endothelial S1pr2 regulates post-ischemic angiogenesis via AKT/eNOS signaling pathway

Caixia Zhou, Yashu Kuang, Qinyu Li, Yunhao Duan, Xiuxiang Liu, Jinnan Yue, Xiaoli Chen, Jie Liu, Yuzhen Zhang, Lin Zhang

Theranostics. 2022; 12(11): 5172–5188. Published online 2022 Jul 4. doi: 10.7150/thno.71585

PMCID:: PMC9274736

Abstract Article PDF–4.6M

Select item 89561839.

Role of sphingosine kinase and sphingosine-1-phosphate receptor in the liver pathology of mice infected with Plasmodium berghei ANKA

Tachpon Techarang, Pitchanee Jariyapong, Chuchard Punsawad

PLoS One. 2022; 17(3): e0266055. Published online 2022 Mar 25. doi: 10.1371/journal.pone.0266055

PMCID:: PMC8956183

Abstract Article PDF–2.7M

Select item 892863010.

Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme

Morag A. Lewis, Neil J. Ingham, Jing Chen, Selina Pearson, Francesca Di Domenico, Sohinder Rekhi, Rochelle Allen, Matthew Drake, Annelore Willaert, Victoria Rook, Johanna Pass, Thomas Keane, David J. Adams, Abigail S. Tucker, Jacqueline K. White, Karen P. Steel

BMC Biol. 2022; 20: 67. Published online 2022 Mar 17. doi: 10.1186/s12915-022-01257-8

PMCID:: PMC8928630

Abstract Article PDF–27M

Select item 851672711.

Follicular dendritic cells restrict interleukin 4 availability in germinal centers and foster memory B cell generation

Lihui Duan, Dan Liu, Hsin Chen, Michelle A. Mintz, Marissa Y. Chou, Dmitri I. Kotov, Ying Xu, Jinping An, Brian J. Laidlaw, Jason G. Cyster

Immunity. Author manuscript; available in PMC 2022 Oct 12.

Published in final edited form as: Immunity. 2021 Oct 12; 54(10): 2256–2272.e6. Published online 2021 Sep 22. doi: 10.1016/j.immuni.2021.08.028

PMCID:: PMC8516727

Abstract Article PDF–1.9M

Select item 843094912.

S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P₁ and S1P₃ Receptor Activation and HIF-2α Stabilization

Redona Hafizi, Faik Imeri, Roland H. Wenger, Andrea Huwiler

Int J Mol Sci. 2021 Sep; 22(17): 9467. Published online 2021 Aug 31. doi: 10.3390/ijms22179467

PMCID:: PMC8430949

Abstract Article PDF–2.0M

Select item 802743813.

Increased S1P induces S1PR2 internalization to blunt the sensitivity of colorectal cancer to 5-fluorouracil via promoting intracellular uracil generation

Yu-hang Zhang, Shu-xiang Cui, Sheng-biao Wan, Shu-hua Wu, Xian-jun Qu

Acta Pharmacol Sin. 2021 Mar; 42(3): 460–469. Published online 2020 Jul 9. doi: 10.1038/s41401-020-0460-0

PMCID:: PMC8027438

Abstract Article PDF–3.8M

Select item 796947514.

Inhibition of sphingosine‐1‐phosphate receptor 2 attenuated ligature‐induced periodontitis in mice

Marquise Snipes, Chao Sun, Hong Yu

Oral Dis. 2021 Jul; 27(5): 1283–1291. Published online 2020 Oct 8. doi: 10.1111/odi.13645

PMCID:: PMC7969475

Abstract Article PDF–1.1M

Select item 786617115.

Role of Sphingosine 1-Phosphate Signalling Axis in Muscle Atrophy Induced by TNFα in C2C12 Myotubes

Caterina Bernacchioni, Veronica Ghini, Roberta Squecco, Eglantina Idrizaj, Rachele Garella, Elisa Puliti, Francesca Cencetti, Paola Bruni, Chiara Donati

Int J Mol Sci. 2021 Feb; 22(3): 1280. Published online 2021 Jan 28. doi: 10.3390/ijms22031280

PMCID:: PMC7866171

Abstract Article PDF–2.7M

Select item 746614216.

Opposing Roles of S1P₃ Receptors in Myocardial Function

Dina Wafa, Nóra Koch, Janka Kovács, Margit Kerék, Richard L. Proia, Gábor J. Tigyi, Zoltán Benyó, Zsuzsanna Miklós

Cells. 2020 Aug; 9(8): 1770. Published online 2020 Jul 24. doi: 10.3390/cells9081770

PMCID:: PMC7466142

Abstract Article PDF–1.8M

Select item 735086617.

S1PR2 deficiency enhances neuropathic pain induced by partial sciatic nerve ligation

Qiang GU, Jin-Chao HOU, Xiang-Ming FANG

Turk J Med Sci. 2019; 49(1): 412–421. Published online 2019 Feb 11. doi: 10.3906/sag-1710-77

PMCID:: PMC7350866

Abstract Article PDF–9.3M

Select item 727452518.

Microbial bile acid metabolites modulate gut RORγ⁺ regulatory T cell homeostasis

Xinyang Song, Ximei Sun, Sungwhan F. Oh, Meng Wu, Yanbo Zhang, Wen Zheng, Naama Geva-Zatorsky, Ray Jupp, Diane Mathis, Christophe Benoist, Dennis L. Kasper

Nature. Author manuscript; available in PMC 2020 Jun 5.

Published in final edited form as: Nature. 2020 Jan; 577(7790): 410–415. Published online 2019 Dec 25. doi: 10.1038/s41586-019-1865-0

PMCID:: PMC7274525

Abstract Article PDF–5.1M

Select item 702216519.

Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy

Andreane Cartier, Tani Leigh, Catherine H. Liu, Timothy Hla

Proc Natl Acad Sci U S A. 2020 Feb 11; 117(6): 3157–3166. Published online 2020 Jan 27. doi: 10.1073/pnas.1906246117

PMCID:: PMC7022165

Abstract Article PDF–2.2M

Select item 694469120.

The orphan nuclear receptor Nr4a1 mediates perinatal neuroinflammation in a murine model of preterm labor

Sarah M. Estrada, Andrew S. Thagard, Mary J. Dehart, Jennifer R. Damicis, Elisabeth M. Dornisch, Danielle L. Ippolito, Irina Burd, Peter G. Napolitano, Nicholas Ieronimakis

Cell Death Dis. 2020 Jan; 11(1): 11. Published online 2020 Jan 6. doi: 10.1038/s41419-019-2196-7