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Items: 1 to 20 of 24

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M
2.
Selenoprotein K enhances STING oligomerization to facilitate antiviral response
Lin Lv, Li Chai, Jie Wang, Mengge Wang, Danhui Qin, Hui Song, Yue Fu, Chunyuan Zhao, Jihui Jia, Wei Zhao, Mutian Jia
PLoS Pathog. 2023 Apr; 19(4): e1011314. Published online 2023 Apr 6. doi: 10.1371/journal.ppat.1011314
PMCID:
PMC10112805
ArticlePDF–3.0M
3.
Selenoprotein K protects skeletal muscle from damage and is required for satellite cells-mediated myogenic differentiation
Shengchen Wang, Xia Zhao, Qingqing Liu, Yue Wang, Shu Li, Shiwen Xu
Redox Biol. 2022 Apr; 50: 102255. Published online 2022 Feb 4. doi: 10.1016/j.redox.2022.102255
PMCID:
PMC8844831
ArticlePDF–15M
4.
Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway
Shi-Zheng Jia, Xin-Wen Xu, Zhong-Hao Zhang, Chen Chen, Yu-Bin Chen, Shao-Ling Huang, Qiong Liu, Peter R. Hoffmann, Guo-Li Song
Redox Biol. 2021 Nov; 47: 102154. Published online 2021 Sep 29. doi: 10.1016/j.redox.2021.102154
PMCID:
PMC8495175
ArticlePDF–5.4M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
ArticlePDF–1.6M
6.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
ArticlePDF–5.1M
7.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
ArticlePDF–3.0M
8.
Selenoprotein K regulation of palmitoylation and calpain cleavage of ASAP2 is required for efficient FcγR-mediated phagocytosis
Robert L. Norton, Gregory J. Fredericks, Zhi Huang, Jeffrey D. Fay, FuKun W. Hoffmann, Peter R. Hoffmann
J Leukoc Biol. 2017 Feb; 101(2): 439–448. Published online 2016 Sep 6. doi: 10.1189/jlb.2A0316-156RR
PMCID:
PMC5235904
Article
9.
Selenoprotein Gene Nomenclature
Vadim N. Gladyshev, Elias S. Arnér, Marla J. Berry, Regina Brigelius-Flohé, Elspeth A. Bruford, Raymond F. Burk, Bradley A. Carlson, Sergi Castellano, Laurent Chavatte, Marcus Conrad, Paul R. Copeland, Alan M. Diamond, Donna M. Driscoll, Ana Ferreiro, Leopold Flohé, Fiona R. Green, Roderic Guigó, Diane E. Handy, Dolph L. Hatfield, John Hesketh, Peter R. Hoffmann, Arne Holmgren, Robert J. Hondal, Michael T. Howard, Kaixun Huang, Hwa-Young Kim, Ick Young Kim, Josef Köhrle, Alain Krol, Gregory V. Kryukov, Byeong Jae Lee, Byung Cheon Lee, Xin Gen Lei, Qiong Liu, Alain Lescure, Alexei V. Lobanov, Joseph Loscalzo, Matilde Maiorino, Marco Mariotti, K. Sandeep Prabhu, Margaret P. Rayman, Sharon Rozovsky, Gustavo Salinas, Edward E. Schmidt, Lutz Schomburg, Ulrich Schweizer, Miljan Simonović, Roger A. Sunde, Petra A. Tsuji, Susan Tweedie, Fulvio Ursini, Philip D. Whanger, Yan Zhang
J Biol Chem. 2016 Nov 11; 291(46): 24036–24040. Published online 2016 Sep 19. doi: 10.1074/jbc.M116.756155
PMCID:
PMC5104929
ArticlePDF–140K
10.
Coordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary Palate
Hidenori Nishihara, Naoki Kobayashi, Chiharu Kimura-Yoshida, Kuo Yan, Olga Bormuth, Qiong Ding, Akiko Nakanishi, Takeshi Sasaki, Mika Hirakawa, Kenta Sumiyama, Yasuhide Furuta, Victor Tarabykin, Isao Matsuo, Norihiro Okada
PLoS Genet. 2016 Oct; 12(10): e1006380. Published online 2016 Oct 14. doi: 10.1371/journal.pgen.1006380
PMCID:
PMC5065162
ArticlePDF–3.4M
11.
Selenoprotein S-dependent Selenoprotein K Binding to p97(VCP) Protein Is Essential for Endoplasmic Reticulum-associated Degradation
Jea Hwang Lee, Ki Jun Park, Jun Ki Jang, Yeong Ha Jeon, Kwan Young Ko, Joon Hyun Kwon, Seung-Rock Lee, Ick Young Kim
J Biol Chem. 2015 Dec 11; 290(50): 29941–29952. Published online 2015 Oct 26. doi: 10.1074/jbc.M115.680215
PMCID:
PMC4706009
ArticlePDF–2.4M
12.
A Novel GLP1 Receptor Interacting Protein ATP6ap2 Regulates Insulin Secretion in Pancreatic Beta Cells
Feihan F. Dai, Alpana Bhattacharjee, Ying Liu, Battsetseg Batchuluun, Ming Zhang, Xinye Serena Wang, Xinyi Huang, Lemieux Luu, Dan Zhu, Herbert Gaisano, Michael B. Wheeler
J Biol Chem. 2015 Oct 9; 290(41): 25045–25061. Published online 2015 Aug 13. doi: 10.1074/jbc.M115.648592
PMCID:
PMC4599009
ArticlePDF–2.7M
13.
Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex
Gregory J. Fredericks, FuKun W. Hoffmann, Aaron H. Rose, Hanna J. Osterheld, Franz M. Hess, Frederic Mercier, Peter R. Hoffmann
Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46): 16478–16483. Published online 2014 Nov 3. doi: 10.1073/pnas.1417176111
PMCID:
PMC4246275
ArticlePDF–1.1M
14.
Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis
Svenja Meiler, Yvonne Baumer, Zhi Huang, Fukun W. Hoffmann, Gregory J. Fredericks, Aaron H. Rose, Robert L. Norton, Peter R. Hoffmann, William A. Boisvert
J Leukoc Biol. 2013 May; 93(5): 771–780. doi: 10.1189/jlb.1212647
PMCID:
PMC3629442
Article
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
ArticlePDF–1.1M
16.
Stimulation of Unprimed Macrophages with Immune Complexes Triggers a Low Output of Nitric Oxide by Calcium-dependent Neuronal Nitric-oxide Synthase
Zhi Huang, FuKun W. Hoffmann, Jeffrey D. Fay, Ann C. Hashimoto, Moti L. Chapagain, Pakieli H. Kaufusi, Peter R. Hoffmann
J Biol Chem. 2012 Feb 10; 287(7): 4492–4502. Published online 2011 Dec 28. doi: 10.1074/jbc.M111.315598
PMCID:
PMC3281602
ArticlePDF–1.6M
17.
Selenoprotein K Binds Multiprotein Complexes and Is Involved in the Regulation of Endoplasmic Reticulum Homeostasis
Valentina A. Shchedrina, Robert A. Everley, Yan Zhang, Steven P. Gygi, Dolph L. Hatfield, Vadim N. Gladyshev
J Biol Chem. 2011 Dec 16; 286(50): 42937–42948. Published online 2011 Oct 20. doi: 10.1074/jbc.M111.310920
PMCID:
PMC3234841
ArticlePDF–2.7M
18.
Selenoprotein K Is a Novel Target of m-Calpain, and Cleavage Is Regulated by Toll-like Receptor-induced Calpastatin in Macrophages
Zhi Huang, FuKun W. Hoffmann, Robert L. Norton, Ann C. Hashimoto, Peter R. Hoffmann
J Biol Chem. 2011 Oct 7; 286(40): 34830–34838. Published online 2011 Aug 17. doi: 10.1074/jbc.M111.265520
PMCID:
PMC3186414
ArticlePDF–1.0M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
ArticlePDF–1.0M
20.
Selenoprotein K knockout mice exhibit deficient calcium flux in immune cells and impaired immune responses
Saguna Verma, FuKun W. Hoffmann, Mukesh Kumar, Zhi Huang, Kelsey Roe, Elizabeth Nguyen-Wu, Ann S. Hashimoto, Peter R. Hoffmann
J Immunol. Author manuscript; available in PMC 2012 Feb 15.
Published in final edited form as: J Immunol. 2011 Feb 15; 186(4): 2127–2137. Published online 2011 Jan 10. doi: 10.4049/jimmunol.1002878
PMCID:
PMC3088479
ArticlePDF–2.5M

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