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Items: 1 to 20 of 63

1.
FNDC5/irisin ameliorates bone loss of type 1 diabetes by suppressing endoplasmic reticulum stress‑mediated ferroptosis
Qianqian Dong, Ziqi Han, Mingdong Gao, Limin Tian
J Orthop Surg Res. 2024; 19: 205. Published online 2024 Mar 30. doi: 10.1186/s13018-024-04701-3
PMCID:
PMC10981808
AbstractArticlePDF–12M
2.
Exercise hormone irisin is a critical regulator of cognitive function
Mohammad R. Islam, Sophia Valaris, Michael F. Young, Erin B. Haley, Renhao Luo, Sabrina F. Bond, Sofia Mazuera, Robert R. Kitchen, Barbara J. Caldarone, Luis E.B. Bettio, Brian R. Christie, Angela B. Schmider, Roy J. Soberman, Antoine Besnard, Mark P. Jedrychowski, Hyeonwoo Kim, Hua Tu, Eunhee Kim, Se Hoon Choi, Rudolph E. Tanzi, Bruce M. Spiegelman, Christiane D. Wrann
Nat Metab. Author manuscript; available in PMC 2023 Jul 3.
Published in final edited form as: Nat Metab. 2021 Aug; 3(8): 1058–1070. Published online 2021 Aug 20. doi: 10.1038/s42255-021-00438-z
Correction in:
Nat Metab. 2021 Oct 7
PMCID:
PMC10317538
AbstractArticlePDF–6.4M
3.
Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson’s Disease
Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xiang
Int J Mol Sci. 2023 May; 24(9): 7830. Published online 2023 Apr 25. doi: 10.3390/ijms24097830
PMCID:
PMC10178565
AbstractArticlePDF–4.7M
4.
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction
Tao Wang, Mengyuan Yu, Hangzhuo Li, Shuguang Qin, Wujing Ren, Yixuan Ma, Wenyan Bo, Yue Xi, Mengxin Cai, Zhenjun Tian
Int J Mol Sci. 2023 Feb; 24(4): 4159. Published online 2023 Feb 19. doi: 10.3390/ijms24044159
PMCID:
PMC9962088
AbstractArticlePDF–3.4M
5.
Irisin Modulates Inflammatory, Angiogenic, and Osteogenic Factors during Fracture Healing
Angela Oranger, Roberta Zerlotin, Cinzia Buccoliero, Lorenzo Sanesi, Giuseppina Storlino, Ernestina Schipani, Kenneth Michael Kozloff, Giorgio Mori, Graziana Colaianni, Silvia Colucci, Maria Grano
Int J Mol Sci. 2023 Feb; 24(3): 1809. Published online 2023 Jan 17. doi: 10.3390/ijms24031809
PMCID:
PMC9915346
AbstractArticlePDF–4.2M
6.
Irisin ameliorates age‐associated sarcopenia and metabolic dysfunction
Mingwei Guo, Jing Yao, Jin Li, Jun Zhang, Dongmei Wang, Hui Zuo, Yi Zhang, Bo Xu, Yinzhao Zhong, Fei Shen, Jian Lu, Shuzhe Ding, Cheng Hu, Lingyan Xu, Junjie Xiao, Xinran Ma
J Cachexia Sarcopenia Muscle. 2023 Feb; 14(1): 391–405. Published online 2022 Dec 12. doi: 10.1002/jcsm.13141
PMCID:
PMC9891925
AbstractArticlePDF–4.1M
7.
Exercise-Linked Skeletal Irisin Ameliorates Diabetes-Associated Osteoporosis by Inhibiting the Oxidative Damage–Dependent miR-150-FNDC5/Pyroptosis Axis
Jyotirmaya Behera, Jessica Ison, Michael J. Voor, Neetu Tyagi
Diabetes. 2022 Dec; 71(12): 2777–2792. Published online 2022 Jul 8. doi: 10.2337/db21-0573
PMCID:
PMC9750954
AbstractArticlePDF–144M
8.
Irisin protects against obesity-related chronic kidney disease by regulating perirenal adipose tissue function in obese mice
Fang Han, Chengxia Kan, Di Wu, Zengguang Kuang, Hongwei Song, Youhong Luo, Le Zhang, Ningning Hou, Xiaodong Sun
Lipids Health Dis. 2022; 21: 115. Published online 2022 Nov 5. doi: 10.1186/s12944-022-01727-6
PMCID:
PMC9636726
AbstractArticlePDF–3.4M
9.
Irisin Attenuates Pathological Neovascularization in Oxygen-Induced Retinopathy Mice
Jieqiong Zhang, Zhifei Liu, Haoqian Wu, Xi Chen, Qiumei Hu, Xue Li, Linlin Luo, Shiyang Ye, Jian Ye
Invest Ophthalmol Vis Sci. 2022 Jun; 63(6): 21. Published online 2022 Jun 23. doi: 10.1167/iovs.63.6.21
PMCID:
PMC9233294
AbstractArticlePDF–9.2M
10.
Fibronectin type III domain‐containing 5 improves aging‐related cardiac dysfunction in mice
Can Hu, Xin Zhang, Min Hu, Teng Teng, Yu‐Pei Yuan, Peng Song, Chun‐Yan Kong, Si‐Chi Xu, Zhen‐Guo Ma, Qi‐Zhu Tang
Aging Cell. 2022 Mar; 21(3): e13556. Published online 2022 Feb 15. doi: 10.1111/acel.13556
PMCID:
PMC8920441
AbstractArticlePDF–1.7M
11.
FNDC5/irisin facilitates muscle−adipose−bone connectivity through ubiquitination-dependent activation of runt-related transcriptional factors RUNX1/2
Xinyu He, Yue Hua, Qian Li, Wei Zhu, Yu Pan, Yilin Yang, Xinyang Li, Mengxiao Wu, Jiyong Wang, Xiaoqing Gan
J Biol Chem. 2022 Mar; 298(3): 101679. Published online 2022 Feb 4. doi: 10.1016/j.jbc.2022.101679
PMCID:
PMC8892030
AbstractArticlePDF–5.9M
12.
Renal failure suppresses muscle irisin expression, and irisin blunts cortical bone loss in mice
Naoyuki Kawao, Miku Kawaguchi, Takashi Ohira, Hiroki Ehara, Yuya Mizukami, Yoshimasa Takafuji, Hiroshi Kaji
J Cachexia Sarcopenia Muscle. 2022 Feb; 13(1): 758–771. Published online 2022 Jan 7. doi: 10.1002/jcsm.12892
PMCID:
PMC8818650
AbstractArticlePDF–10M
13.
Myokine Irisin promotes osteogenesis by activating BMP/SMAD signaling via αV integrin and regulates bone mass in mice
Yuan Xue, Sihan Hu, Chichi Chen, Jiachen He, Jie Sun, Yesheng Jin, Yuanshu Zhang, Guoqing Zhu, Qin Shi, Yongjun Rui
Int J Biol Sci. 2022; 18(2): 572–584. Published online 2022 Jan 1. doi: 10.7150/ijbs.63505
PMCID:
PMC8741853
AbstractArticlePDF–3.0M
14.
Exercise-Induced Irisin Decreases Inflammation and Improves NAFLD by Competitive Binding with MD2
Weiwei Zhu, Namood E Sahar, Hafiz Muhammad Ahmad Javaid, Eun Seon Pak, Guang Liang, Yi Wang, Hunjoo Ha, Joo Young Huh
Cells. 2021 Dec; 10(12): 3306. Published online 2021 Nov 25. doi: 10.3390/cells10123306
PMCID:
PMC8699279
AbstractArticlePDF–3.4M
15.
Roles and Mechanisms of Irisin in Attenuating Pathological Features of Osteoarthritis
Xiangfen Li, Xiaofang Zhu, Hongle Wu, Thomas E. Van Dyke, Xiaoyang Xu, Elise F. Morgan, Wenyu Fu, Chuanju Liu, Qisheng Tu, Dingming Huang, Jake Chen
Front Cell Dev Biol. 2021; 9: 703670. Published online 2021 Sep 28. doi: 10.3389/fcell.2021.703670
PMCID:
PMC8509718
AbstractArticlePDF–3.6M
16.
Irisin levels in the serum and cerebrospinal fluid of patients with multiple sclerosis and the expression and distribution of irisin in experimental autoimmune encephalomyelitis
Qiu‐Xia Zhang, Sheng‐Nan Zhang, Lin‐Jie Zhang, Da‐Qi Zhang, Li Yang
Clin Exp Immunol. 2021 Nov; 206(2): 208–215. Published online 2021 Sep 15. doi: 10.1111/cei.13656
PMCID:
PMC8506135
AbstractArticlePDF–728K
17.
Irisin alleviates obesity-related spermatogenesis dysfunction via the regulation of the AMPKα signalling pathway
Yang Mu, Huang-Guan Dai, Ling-Bo Luo, Jing Yang
Reprod Biol Endocrinol. 2021; 19: 135. Published online 2021 Sep 8. doi: 10.1186/s12958-021-00821-1
PMCID:
PMC8424900
AbstractArticlePDF–3.3M
18.
Progress and Challenges in the Biology of FNDC5 and Irisin
Steffen Maak, Frode Norheim, Christian A Drevon, Harold P Erickson
Endocr Rev. 2021 Aug; 42(4): 436–456. Published online 2021 Jan 25. doi: 10.1210/endrev/bnab003
PMCID:
PMC8284618
AbstractArticle
19.
NAD+-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin
Dong-Jie Li, Si-Jia Sun, Jiang-Tao Fu, Shen-Xi Ouyang, Qin-Jie Zhao, Li Su, Qing-Xi Ji, Di-Ynag Sun, Jia-Hui Zhu, Guo-Yan Zhang, Jia-Wei Ma, Xiu-Ting Lan, Yi Zhao, Jie Tong, Guo-Qiang Li, Fu-Ming Shen, Pei Wang
Theranostics. 2021; 11(9): 4381–4402. Published online 2021 Feb 25. doi: 10.7150/thno.53652
PMCID:
PMC7977447
AbstractArticlePDF–5.7M
20.
Associations of Circulating Irisin with FNDC5 Expression in Fat and Muscle in Type 1 and Type 2 Diabetic Mice
Songling Jiang, Lingjuan Piao, Eun Bi Ma, Hunjoo Ha, Joo Young Huh
Biomolecules. 2021 Feb; 11(2): 322. Published online 2021 Feb 20. doi: 10.3390/biom11020322
PMCID:
PMC7924053
AbstractArticlePDF–624K

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