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Select item 104805351.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 102778142.

LncRNA gadd7 promotes mitochondrial membrane potential decrease and apoptosis of alveolar type II epithelial cells by positively regulating MFN1 in an in vitro model of hyperoxia-induced acute lung injury

Guoyue Liu, Cunzhi Yin, Mingjiang Qian, Xuan Xiao, Hang Wu, Fujian Fu

Eur J Histochem. 2023 Mar 20; 67(2): 3535. Published online 2023 May 31. doi: 10.4081/ejh.2023.3535

PMCID:: PMC10277814

Abstract Article PDF–659K

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 91197364.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 87671965.

Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria

Marta Vranas, Yang Lu, Shafqat Rasool, Nathalie Croteau, Jonathan D. Krett, Véronique Sauvé, Kalle Gehring, Edward A. Fon, Thomas M. Durcan, Jean-François Trempe

Open Biol. 2022 Jan; 12(1): 210255. Published online January 19, 2022. doi: 10.1098/rsob.210255

PMCID:: PMC8767196

Abstract Article PDF–2.5M

Select item 85192886.

Mitochondrial Fusion Mediated by Mitofusin 1 Regulates Macrophage Mycobactericidal Activity by Enhancing Autophagy

Yuping Ning, Yi Cai, Youchao Dai, Fuxiang Li, Siwei Mo, Oliver Werz, Xinchun Chen

Infect Immun. 2021 Nov; 89(11): e00306-21. Prepublished online 2021 Aug 9. Published online 2021 Oct 15. doi: 10.1128/IAI.00306-21

PMCID:: PMC8519288

Abstract Article PDF–2.1M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81052718.

Intracellular AIBP regulates oxidized LDL-induced mitophagy in macrophages

Soo-Ho Choi, Colin Agatisa-Boyle, Ayelet Gonen, Alisa Kim, Jungsu Kim, Elena Alekseeva, Sotirios Tsimikas, Yury I. Miller

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Feb; 41(2): e82–e96. Published online 2020 Dec 24. doi: 10.1161/ATVBAHA.120.315485

PMCID:: PMC8105271

Abstract Article PDF–1.4M

Select item 79909249.

Cardiac mitofusin-1 is reduced in non-responding patients with idiopathic dilated cardiomyopathy

Yung Ting Hsiao, Ippei Shimizu, Takayuki Wakasugi, Yohko Yoshida, Ryutaro Ikegami, Yuka Hayashi, Masayoshi Suda, Goro Katsuumi, Masaaki Nakao, Takuya Ozawa, Daisuke Izumi, Takeshi Kashimura, Kazuyuki Ozaki, Tomoyoshi Soga, Tohru Minamino

Sci Rep. 2021; 11: 6722. Published online 2021 Mar 24. doi: 10.1038/s41598-021-86209-y

PMCID:: PMC7990924

Abstract Article PDF–7.4M

Select item 797970510.

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1

Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu

NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3

PMCID:: PMC7979705

Abstract Article PDF–6.8M

Select item 741581211.

Lentinan-functionalized Selenium Nanoparticles target Tumor Cell Mitochondria via TLR4/TRAF3/MFN1 pathway

Hui-Juan Liu, Yuan Qin, Zi-Han Zhao, Yang Zhang, Jia-Huan Yang, Deng-Hui Zhai, Fang Cui, Ce Luo, Man-Xi Lu, Piao-Piao Liu, Heng-Wei Xu, Kun Li, Bo Sun, Shuang Chen, Hong-Gang Zhou, Cheng Yang, Tao Sun

Theranostics. 2020; 10(20): 9083–9099. Published online 2020 Jul 11. doi: 10.7150/thno.46467

Correction in:: Theranostics. 2022; 12(17): 7645.

PMCID:: PMC7415812

Abstract Article PDF–3.8M

Select item 740715912.

The GDP-Bound State of Mitochondrial Mfn1 Induces Membrane Adhesion of Apposing Lipid Vesicles through a Cooperative Binding Mechanism

Andrés Tolosa-Díaz, Víctor G. Almendro-Vedia, Paolo Natale, Iván López-Montero

Biomolecules. 2020 Jul; 10(7): 1085. Published online 2020 Jul 21. doi: 10.3390/biom10071085

PMCID:: PMC7407159

Abstract Article PDF–1.2M

Select item 727904913.

EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired

Marioara Chiritoiu, Gabriela N. Chiritoiu, Cristian V. A. Munteanu, Florin Pastrama, N. Erwin Ivessa, Stefana M. Petrescu

Int J Mol Sci. 2020 May; 21(10): 3468. Published online 2020 May 14. doi: 10.3390/ijms21103468

PMCID:: PMC7279049

Abstract Article PDF–12M

Select item 712510114.

Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses

Daisuke Oikawa, Yusuke Sato, Fumiaki Ohtake, Keidai Komakura, Kazuki Hanada, Koji Sugawara, Seigo Terawaki, Yukari Mizukami, Hoang T. Phuong, Kiyosei Iio, Shingo Obika, Masaya Fukushi, Takashi Irie, Daisuke Tsuruta, Shinji Sakamoto, Keiji Tanaka, Yasushi Saeki, Shuya Fukai, Fuminori Tokunaga

Commun Biol. 2020; 3: 163. Published online 2020 Apr 3. doi: 10.1038/s42003-020-0882-8

PMCID:: PMC7125101

Abstract Article PDF–4.7M

Select item 705227215.

MFN1-dependent alteration of mitochondrial dynamics drives hepatocellular carcinoma metastasis by glucose metabolic reprogramming

Ze Zhang, Tian-En Li, Mo Chen, Da Xu, Ying Zhu, Bei-Yuan Hu, Zhi-Fei Lin, Jun-Jie Pan, Xuan Wang, Chao Wu, Yan Zheng, Lu Lu, Hu-Liang Jia, Song Gao, Qiong-Zhu Dong, Lun-Xiu Qin

Br J Cancer. 2020 Jan 21; 122(2): 209–220. Published online 2019 Dec 10. doi: 10.1038/s41416-019-0658-4

PMCID:: PMC7052272

Abstract Article PDF–2.6M

Select item 701710416.

Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth

Meng Li, Ling Wang, Yijin Wang, Shaoshi Zhang, Guoying Zhou, Ruby Lieshout, Buyun Ma, Jiaye Liu, Changbo Qu, Monique M. A. Verstegen, Dave Sprengers, Jaap Kwekkeboom, Luc J. W. van der Laan, Wanlu Cao, Maikel P. Peppelenbosch, Qiuwei Pan

Cells. 2020 Jan; 9(1): 121. Published online 2020 Jan 4. doi: 10.3390/cells9010121

PMCID:: PMC7017104

Abstract Article PDF–5.3M

Select item 684450417.

Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy

Hongxu Xian, Yih-Cherng Liou

Autophagy. 2019; 15(12): 2107–2125. Published online 2019 Mar 28. doi: 10.1080/15548627.2019.1596494

PMCID:: PMC6844504

Abstract Article PDF–9.5M

Select item 677813718.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 659455119.

PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin

Cell Rep. Author manuscript; available in PMC 2019 Jun 26.

Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060

PMCID:: PMC6594551

Abstract Article PDF–1.4M

Select item 607772220.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

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