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Select item 109841011.

PML‐mediated nuclear loosening permits immunomodulation of mesenchymal stem/stromal cells under inflammatory conditions

Yunpeng Chu, Zishan Jiang, Zheng Gong, Xiaocao Ji, Mengting Zhu, Qianwen Shang, Pixia Gong, Lijuan Cao, Yongjing Chen, Peishan Li, Changshun Shao, Yufang Shi

Cell Prolif. 2024 Apr; 57(4): e13566. Published online 2023 Oct 20. doi: 10.1111/cpr.13566

PMCID:: PMC10984101

Abstract Article PDF–4.1M

Select item 109054642.

Clinical Relevance of Differential RARα and PPARβ/δ Expression in Myelodysplastic Syndromes

NIKOLAY KALITIN, GALINA DUDINA, NATALIA KOSTRITSA, ANASTASIYA SIVIRINOVA, ANDREY VAIMAN, AIDA KARAMYSHEVA

In Vivo. 2024 Mar-Apr; 38(2): 657–664. Published online 2024 Mar 3. doi: 10.21873/invivo.13486

PMCID:: PMC10905464

Abstract Article PDF–417K

Select item 106390713.

PML modulates epigenetic composition of chromatin to regulate expression of pro-metastatic genes in triple-negative breast cancer

Cristina Fracassi, Martina Ugge', Mohamed Abdelhalim, Ettore Zapparoli, Matilde Simoni, Daniela Magliulo, Davide Mazza, Dejan Lazarevic, Marco J Morelli, Philippe Collas, Rosa Bernardi

Nucleic Acids Res. 2023 Nov 10; 51(20): 11024–11039. Published online 2023 Oct 12. doi: 10.1093/nar/gkad819

PMCID:: PMC10639071

Abstract Article PDF–2.0M

Select item 105658764.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 105529025.

Promyelocytic leukemia protein regulates angiogenesis and epithelial–mesenchymal transition to limit metastasis in MDA‐MB‐231 breast cancer cells

Amalia P. Vogiatzoglou, Syrago Spanou, Nikoleta Sachini, Elias Drakos, Christoforos Nikolaou, Takis Makatounakis, Androniki Kretsovali, Joseph Papamatheakis

Mol Oncol. 2023 Oct; 17(10): 2090–2108. Published online 2023 Sep 4. doi: 10.1002/1878-0261.13501

PMCID:: PMC10552902

Abstract Article PDF–11M

Select item 102431166.

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification

Camila M. Aprosoff, Boris J.A. Dyakov, Vivian H.W. Cheung, Cassandra J. Wong, Mikaela Palandra, Anne-Claude Gingras, Haley D.M. Wyatt

J Proteome Res. 2023 Jun 2; 22(6): 1660–1681. Published online 2023 Apr 18. doi: 10.1021/acs.jproteome.2c00706

PMCID:: PMC10243116

Abstract Article PDF–13M

Select item 102374227.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101231248.

PML and PML-like exonucleases restrict retrotransposons in jawed vertebrates

Sabateeshan Mathavarajah, Kathleen L Vergunst, Elias B Habib, Shelby K Williams, Raymond He, Maria Maliougina, Mika Park, Jayme Salsman, Stéphane Roy, Ingo Braasch, Andrew J Roger, David N Langelaan, Graham Dellaire

Nucleic Acids Res. 2023 Apr 24; 51(7): 3185–3204. Published online 2023 Mar 13. doi: 10.1093/nar/gkad152

PMCID:: PMC10123124

Abstract Article PDF–6.1M

Select item 100428639.

Hyperthermia promotes degradation of the acute promyelocytic leukemia driver oncoprotein ZBTB16/RARα

Qian-qian Wang, Liaqat Hussain, Pei-han Yu, Chang Yang, Chen-ying Zhu, Ya-fang Ma, Si-chun Wang, Tao Yang, Yuan-yuan Kang, Wen-juan Yu, Yasen Maimaitiyiming, Hua Naranmandura

Acta Pharmacol Sin. 2023 Apr; 44(4): 822–831. Published online 2022 Oct 10. doi: 10.1038/s41401-022-01001-6

PMCID:: PMC10042863

Abstract Article PDF–3.7M

Select item 1000589810.

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA

Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay

J Cell Biol. 2023 Apr 3; 222(4): e202201027. Published online 2023 Feb 28. doi: 10.1083/jcb.202201027

PMCID:: PMC10005898

Abstract Article PDF–6.7M

Select item 995044711.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 991141012.

Multi-omics and machine learning reveal context-specific gene regulatory activities of PML::RARA in acute promyelocytic leukemia

William Villiers, Audrey Kelly, Xiaohan He, James Kaufman-Cook, Abdurrahman Elbasir, Halima Bensmail, Paul Lavender, Richard Dillon, Borbála Mifsud, Cameron S. Osborne

Nat Commun. 2023; 14: 724. Published online 2023 Feb 9. doi: 10.1038/s41467-023-36262-0

PMCID:: PMC9911410

Abstract Article PDF–3.7M

Select item 991000913.

Crosstalk between PML and p53 in response to TGF-β1: A new mechanism of cardiac fibroblast activation

Di Huang, Dan Zhao, Ming Li, Si-Yu Chang, Ya-Dong Xue, Ning Xu, Si-Jia Li, Nan-Nan Tang, Li-Ling Gong, Yi-Ning Liu, Hang Yu, Qing-Sui Li, Peng-Yu Li, Jia-Li Liu, Hai-Xin Chen, Ming-Bin Liu, Wan-Yu Zhang, Xing-Miao Zhao, Xian-Zhi Lang, Zhen-Dong Li, Yu Liu, Zhi-Yong Ma, Jia-Min Li, Ning Wang, Hai Tian, Ben-Zhi Cai

Int J Biol Sci. 2023; 19(3): 994–1006. Published online 2023 Jan 22. doi: 10.7150/ijbs.76214

PMCID:: PMC9910009

Abstract Article PDF–5.7M

Select item 976969814.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 971308015.

PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment

Sonia Missiroli, Mariasole Perrone, Roberta Gafà, Francesco Nicoli, Massimo Bonora, Giampaolo Morciano, Caterina Boncompagni, Saverio Marchi, Magdalena Lebiedzinska-Arciszewska, Bianca Vezzani, Giovanni Lanza, Franz Kricek, Alessandro Borghi, Francesco Fiorica, Keisuke Ito, Mariusz R. Wieckowski, Francesco Di Virgilio, Luigi Abelli, Paolo Pinton, Carlotta Giorgi

Cell Death Differ. 2023 Feb; 30(2): 429–441. Published online 2022 Nov 30. doi: 10.1038/s41418-022-01095-9

PMCID:: PMC9713080

Abstract Article PDF–4.6M

Select item 970808616.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676