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Items: 1 to 20 of 229

1.
Pan PPAR agonist stimulation of induced MSCs produces extracellular vesicles with enhanced renoprotective effect for acute kidney injury
Hongduk Kim, Seul Ki Lee, Sungok Hong, Tae Sub Park, Jimin Kim, Soo Kim, Tae Min Kim
Stem Cell Res Ther. 2024; 15: 9. Published online 2024 Jan 2. doi: 10.1186/s13287-023-03577-0
PMCID:
PMC10763307
AbstractArticlePDF–2.8M
2.
The association of ACE, ACTN3 and PPARA gene variants with strength phenotypes in middle school-age children
Ildus I. Ahmetov, Dmitry N. Gavrilov, Irina V. Astratenkova, Anastasiya M. Druzhevskaya, Alexandr V. Malinin, Elena E. Romanova, Victor A. Rogozkin
J Physiol Sci. 2013 Jan; 63(1): 79–85. Published online 2012 Sep 16. doi: 10.1007/s12576-012-0233-8
PMCID:
PMC10717977
AbstractArticlePDF–207K
3.
Hepatic fibrosis: Targeting peroxisome proliferator-activated receptor alpha from mechanism to medicines
Lijun Gong, Fang Wei, Frank J. Gonzalez, Guolin Li
Hepatology. Author manuscript; available in PMC 2023 Nov 27.
Published in final edited form as: Hepatology. 2023 Nov 1; 78(5): 1625–1653. Published online 2023 Jan 3. doi: 10.1097/HEP.0000000000000182
PMCID:
PMC10681123
AbstractArticlePDF–1.3M
4.
Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity
Kenji Saito, Motohiro Sekiya, Kenta Kainoh, Ryunosuke Yoshino, Akio Hayashi, Song-Iee Han, Masaya Araki, Hiroshi Ohno, Yoshinori Takeuchi, Tomomi Tsuyuzaki, Daichi Yamazaki, Chen Wanpei, Lisa Hada, Sho Watanabe, Putu Indah Paramita Adi Putri, Yuki Murayama, Yoko Sugano, Yoshinori Osaki, Hitoshi Iwasaki, Naoya Yahagi, Hiroaki Suzuki, Takafumi Miyamoto, Takashi Matsuzaka, Hitoshi Shimano
J Biol Chem. 2023 Jul; 299(7): 104890. Published online 2023 Jun 5. doi: 10.1016/j.jbc.2023.104890
PMCID:
PMC10339064
AbstractArticlePDF–2.0M
5.
Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez
Hepatology. 2023 Jan; 77(1): 239–255. Published online 2022 May 15. doi: 10.1002/hep.32538
PMCID:
PMC9970020
AbstractArticlePDF–1.8M
6.
A proteome-scale map of the SARS-CoV-2–human contactome
Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun
Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z
PMCID:
PMC9849141
AbstractArticlePDF–7.1M
7.
PPARα: An emerging target of metabolic syndrome, neurodegenerative and cardiovascular diseases
Yijun Lin, Yan Wang, Pei-feng Li
Front Endocrinol (Lausanne) 2022; 13: 1074911. Published online 2022 Dec 16. doi: 10.3389/fendo.2022.1074911
PMCID:
PMC9800994
AbstractArticlePDF–1.2M
8.
Exploring the Regulatory Role of ncRNA in NAFLD: A Particular Focus on PPARs
Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Ramkumar Katturajan, Sandra Kannampuzha, Reshma Murali, Arunraj Namachivayam, Raja Ganesan, Kaviyarasi Renu, Abhijit Dey, Balachandar Vellingiri, Sabina Evan Prince
Cells. 2022 Dec; 11(24): 3959. Published online 2022 Dec 7. doi: 10.3390/cells11243959
PMCID:
PMC9777112
AbstractArticlePDF–2.5M
9.
Suppression of Hepatic PPARα in Primary Biliary Cholangitis Is Modulated by miR-155
Monika Adamowicz, Agnieszka Kempinska-Podhorodecka, Joanna Abramczyk, Jesus M. Banales, Piotr Milkiewicz, Malgorzata Milkiewicz
Cells. 2022 Sep; 11(18): 2880. Published online 2022 Sep 15. doi: 10.3390/cells11182880
PMCID:
PMC9496720
AbstractArticlePDF–2.7M
10.
Reduced peroxisome proliferator-activated receptor-α and bile acid nuclear receptor NR1H4/FXR may affect the hepatic immune microenvironment of biliary atresia
Yingxuan Ma, Li Lu, Kezhe Tan, Zhi Li, Ting Guo, Yibo Wu, Wei Wu, Lulu Zheng, Feilong Fan, Jiayu Mo, Zhenhua Gong
Front Immunol. 2022; 13: 875593. Published online 2022 Aug 25. doi: 10.3389/fimmu.2022.875593
PMCID:
PMC9454303
AbstractArticlePDF–14M
11.
PARP1-mediated PPARα poly(ADP-ribosyl)ation suppresses fatty acid oxidation in non-alcoholic fatty liver disease
Kun Huang, Meng Du, Xin Tan, Ling Yang, Xiangrao Li, Yuhan Jiang, Cheng Wang, Fengxiao Zhang, Feng Zhu, Min Cheng, Qinglin Yang, Liqing Yu, Lin Wang, Dan Huang, Kai Huang
J Hepatol. Author manuscript; available in PMC 2022 Jul 18.
Published in final edited form as: J Hepatol. 2017 May; 66(5): 962–977. Published online 2016 Dec 12. doi: 10.1016/j.jhep.2016.11.020
PMCID:
PMC9289820
AbstractArticlePDF–3.3M
12.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
13.
Fat mass and obesity–associated protein promotes liver steatosis by targeting PPARα
Xiaohui Wei, Jielei Zhang, Min Tang, Xuejiao Wang, Nengguang Fan, Yongde Peng
Lipids Health Dis. 2022; 21: 29. Published online 2022 Mar 13. doi: 10.1186/s12944-022-01640-y
PMCID:
PMC8918283
AbstractArticlePDF–2.5M
14.
PXR Suppresses PPARα-Dependent HMGCS2 Gene Transcription by Inhibiting the Interaction between PPARα and PGC1α
Ryota Shizu, Kanako Ezaki, Takumi Sato, Ayaka Sugawara, Takuomi Hosaka, Takamitsu Sasaki, Kouichi Yoshinari
Cells. 2021 Dec; 10(12): 3550. Published online 2021 Dec 16. doi: 10.3390/cells10123550
PMCID:
PMC8700377
AbstractArticlePDF–2.5M
15.
Dietary excess regulates absorption and surface of gut epithelium through intestinal PPARα
Ozren Stojanović, Jordi Altirriba, Dorothée Rigo, Martina Spiljar, Emilien Evrard, Benedek Roska, Salvatore Fabbiano, Nicola Zamboni, Pierre Maechler, Françoise Rohner-Jeanrenaud, Mirko Trajkovski
Nat Commun. 2021; 12: 7031. Published online 2021 Dec 2. doi: 10.1038/s41467-021-27133-7
PMCID:
PMC8639731
AbstractArticlePDF–2.6M
16.
The PPARα and PPARγ Epigenetic Landscape in Cancer and Immune and Metabolic Disorders
Jesús Porcuna, Jorge Mínguez-Martínez, Mercedes Ricote
Int J Mol Sci. 2021 Oct; 22(19): 10573. Published online 2021 Sep 30. doi: 10.3390/ijms221910573
PMCID:
PMC8508752
AbstractArticlePDF–1.0M
17.
The Role of PPAR Alpha in the Modulation of Innate Immunity
Maja Grabacka, Małgorzata Pierzchalska, Przemysław M. Płonka, Piotr Pierzchalski
Int J Mol Sci. 2021 Oct; 22(19): 10545. Published online 2021 Sep 29. doi: 10.3390/ijms221910545
PMCID:
PMC8508635
AbstractArticlePDF–23M
18.
PAQR9 regulates hepatic ketogenesis and fatty acid oxidation during fasting by modulating protein stability of PPARα
Yijun Lin, Lingling Chen, Xue You, Zixuan Li, Chenchen Li, Yan Chen
Mol Metab. 2021 Nov; 53: 101331. Published online 2021 Aug 30. doi: 10.1016/j.molmet.2021.101331
PMCID:
PMC8452888
AbstractArticlePDF–3.3M
19.
Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity
Francisco Sáez-Orellana, Thomas Leroy, Floriane Ribeiro, Anna Kreis, Karelle Leroy, Fanny Lalloyer, Eric Baugé, Bart Staels, Charles Duyckaerts, Jean-Pierre Brion, Philippe Gailly, Jean-Noël Octave, Nathalie Pierrot
JCI Insight. 2021 Aug 23; 6(16): e150099. Published online 2021 Aug 23. doi: 10.1172/jci.insight.150099
PMCID:
PMC8410016
AbstractArticlePDF–1.3M
20.
Heterodimer formation with retinoic acid receptor RXRα modulates coactivator recruitment by peroxisome proliferator-activated receptor PPARγ
Whitney Kilu, Daniel Merk, Dieter Steinhilber, Ewgenij Proschak, Jan Heering
J Biol Chem. 2021 Jul; 297(1): 100814. Published online 2021 May 31. doi: 10.1016/j.jbc.2021.100814
PMCID:
PMC8258697
AbstractArticlePDF–2.8M

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