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Select item 105732961.

HtrA3: a promising prognostic biomarker and therapeutic target for head and neck squamous cell carcinoma

Yan Chen, Jianfeng Yang, Hangbin Jin, Weiwei Wen, Ying Xu, Xiaofeng Zhang, Yu Wang

PeerJ. 2023; 11: e16237. Published online 2023 Oct 10. doi: 10.7717/peerj.16237

PMCID:: PMC10573296

Abstract Article PDF–12M

Select item 97340292.

mmu-lncRNA 121686/hsa-lncRNA 520657 induced by METTL3 drive the progression of AKI by targeting miR-328-5p/HtrA3 signaling axis

Jian Pan, Yuxin Xie, Huiling Li, Xiaozhou Li, Junxiang Chen, Xiangfeng Liu, Jun Zhou, Xianming Tang, Zhibiao He, Zhenyu Peng, Hongliang Zhang, Yijian Li, Xudong Xiang, Yunchang Yuan, Dongshan Zhang

Mol Ther. 2022 Dec 7; 30(12): 3694–3713. Published online 2022 Jul 21. doi: 10.1016/j.ymthe.2022.07.014

PMCID:: PMC9734029

Abstract Article PDF–6.9M

Select item 87598573.

Study on the Correlation between the Levels of HtrA3 and TGF-β2 in Late Pregnancy and Preeclampsia

Wenying Huang, Shuxuan Zhang

J Healthc Eng. 2022; 2022: 4453646. Published online 2022 Jan 7. doi: 10.1155/2022/4453646

PMCID:: PMC8759857

Abstract Article PDF–1.7M

Select item 82501314.

Host PDZ‐containing proteins targeted by SARS‐CoV‐2

Célia Caillet‐Saguy, Fabien Durbesson, Veronica V. Rezelj, Gergö Gogl, Quang Dinh Tran, Jean‐Claude Twizere, Marco Vignuzzi, Renaud Vincentelli, Nicolas Wolff

FEBS J. 2021 Sep; 288(17): 5148–5162. Published online 2021 May 1. doi: 10.1111/febs.15881

PMCID:: PMC8250131

Abstract Article PDF–1.4M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78141336.

Hsa-miR-494-3p attenuates gene HtrA3 transcription to increase inflammatory response in hypoxia/reoxygenation HK2 Cells

Qian Gong, Zhi-ming Shen, Zhe Sheng, Shi Jiang, Sheng-lin Ge

Sci Rep. 2021; 11: 1665. Published online 2021 Jan 18. doi: 10.1038/s41598-021-81113-x

PMCID:: PMC7814133

Abstract Article PDF–2.1M

Select item 73125157.

Expression of HTRA Genes and Its Association with Microsatellite Instability and Survival of Patients with Colorectal Cancer

Dorota Zurawa-Janicka, Jarek Kobiela, Tomasz Slebioda, Rafal Peksa, Marcin Stanislawowski, Piotr Mieczyslaw Wierzbicki, Tomasz Wenta, Barbara Lipinska, Zbigniew Kmiec, Wojciech Biernat, Andrzej Jacek Lachinski, Zbigniew Sledzinski

Int J Mol Sci. 2020 Jun; 21(11): 3947. Published online 2020 May 31. doi: 10.3390/ijms21113947

PMCID:: PMC7312515

Abstract Article PDF–3.7M

Select item 69938608.

A distinct concerted mechanism of structural dynamism defines activity of human serine protease HtrA3

Saujanya Acharya, Shubhankar Dutta, Kakoli Bose

Biochem J. 2020 Jan 31; 477(2): 407–429. Prepublished online 2020 Jan 3. Published online 2020 Jan 30. doi: 10.1042/BCJ20190706

PMCID:: PMC6993860

Abstract Article PDF–7.9M

Select item 67781379.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 658002410.

Long intergenic non-coding RNA 00467 promotes lung adenocarcinoma proliferation, migration and invasion by binding with EZH2 and repressing HTRA3 expression

Xianghai Wang, Hongbing Liu, Kaikai Shen, Xianhui Pan, Yuqing Wei, Tangfeng Lv, Yong Song

Mol Med Rep. 2019 Jul; 20(1): 640–654. Published online 2019 May 23. doi: 10.3892/mmr.2019.10292

PMCID:: PMC6580024

Abstract Article PDF–2.8M

Select item 599939611.

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation

Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel

eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879

PMCID:: PMC5999396

Abstract Article PDF–3.6M

Select item 557459612.

Paeoniflorin suppresses pancreatic cancer cell growth by upregulating HTRA3 expression

Yuejun Li, Lili Gong, Ruili Qi, Qian Sun, Xinxin Xia, Haihui He, Jianshu Ren, Ouning Zhu, Debin Zhuo

Drug Des Devel Ther. 2017; 11: 2481–2491. Published online 2017 Aug 23. doi: 10.2147/DDDT.S134518

PMCID:: PMC5574596

Abstract Article PDF–2.8M

Select item 555356813.

A role for mitochondrial translation in promotion of viability in K-Ras mutant cells

Timothy D. Martin, Danielle R. Cook, Mei Yuk Choi, Mamie Z. Li, Kevin M. Haigis, Stephen J. Elledge

Cell Rep. Author manuscript; available in PMC 2017 Aug 11.

Published in final edited form as: Cell Rep. 2017 Jul 11; 20(2): 427–438. doi: 10.1016/j.celrep.2017.06.061

PMCID:: PMC5553568

Abstract Article PDF–1.8M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 549687215.

Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood

Ying Li, Lois A. Salamonsen, Jonathan Hyett, Fabricio da Silva Costa, Guiying Nie

Sci Rep. 2017; 7: 4627. Published online 2017 Jul 4. doi: 10.1038/s41598-017-04867-3

PMCID:: PMC5496872

Abstract Article PDF–2.4M

Select item 513003916.

High temperature requirement A3 (HTRA3) expression predicts postoperative recurrence and survival in patients with non-small-cell lung cancer

Jingya Zhao, Jing Zhang, Xin Zhang, Mingxiang Feng, Jieming Qu

Oncotarget. 2016 Jun 28; 7(26): 40725–40734. Published online 2016 May 4. doi: 10.18632/oncotarget.9173

PMCID:: PMC5130039

Abstract Article PDF–1.7M

Select item 461721117.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 448151318.

Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains

Przemyslaw Glaza, Jerzy Osipiuk, Tomasz Wenta, Dorota Zurawa-Janicka, Miroslaw Jarzab, Adam Lesner, Bogdan Banecki, Joanna Skorko-Glonek, Andrzej Joachimiak, Barbara Lipinska

PLoS One. 2015; 10(6): e0131142. Published online 2015 Jun 25. doi: 10.1371/journal.pone.0131142

PMCID:: PMC4481513

Abstract Article PDF–6.7M

Select item 413279619.

Functional Antagonism between High Temperature Requirement Protein A (HtrA) Family Members Regulates Trophoblast Invasion

Yao-Yu Chen, Pei-Yun Chuang, Chie-Pein Chen, Yueh-Ho Chiu, Hsiao-Fan Lo, Mei-Leng Cheong, Jyun-Yuang Huang, Pao-Lin Kuo, Hungwen Chen

J Biol Chem. 2014 Aug 15; 289(33): 22958–22968. Published online 2014 Jul 7. doi: 10.1074/jbc.M114.576744

PMCID:: PMC4132796

Abstract Article PDF–3.6M

Select item 345799320.

HtrA3 as an Early Marker for Preeclampsia: Specific Monoclonal Antibodies and Sensitive High-Throughput Assays for Serum Screening

Kemperly Dynon, Sophea Heng, Michelle Puryer, Ying Li, Kelly Walton, Yaeta Endo, Guiying Nie

PLoS One. 2012; 7(9): e45956. Published online 2012 Sep 25. doi: 10.1371/journal.pone.0045956

PMCID:: PMC3457993

Abstract Article PDF–5.0M

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