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Select item 110342351.

β1 Integrin triggering affects leukemic cell line sensitivity to natural killer cells

Gonzalo Rubio, Xabier Ferez, Ana Mora, Jesus Galvez, Antonio Chicano, Pilar Garcia-Peñarrubia

Cancer Immunol Immunother. 2002 May; 51(3): 130–138. Published online 2002 Feb 28. doi: 10.1007/s00262-002-0264-8

PMCID:: PMC11034235

Abstract Article PDF–182K

Select item 109646832.

A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection

Mingming Xue, Lingyu Xing, Yilin Yang, Mian Shao, Fengqing Liao, Feixiang Xu, Yumei Chen, Sheng Wang, Bin Chen, Chenling Yao, Guorong Gu, Chaoyang Tong

BMC Cardiovasc Disord. 2024; 24: 180. Published online 2024 Mar 26. doi: 10.1186/s12872-024-03778-2

PMCID:: PMC10964683

Abstract Article PDF–4.4M

Select item 109168663.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 108508184.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 108119055.

Integrinβ-1 in disorders and cancers: molecular mechanisms and therapeutic targets

Chen Su, Jie Mo, Shuilin Dong, Zhibin Liao, Bixiang Zhang, Peng Zhu

Cell Commun Signal. 2024; 22: 71. Published online 2024 Jan 26. doi: 10.1186/s12964-023-01338-3

PMCID:: PMC10811905

Abstract Article PDF–5.2M

Select item 108046016.

Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1

Tianzhu Lv, Hongjing Liu, Ling Mao, Yanrong Song, Lili Liao, Kun Zhong, Binbin Shuai, Yingkun Luo, Tingting Guo, Wentao Huang, Shenyingjie Zhang

BMC Cancer. 2024; 24: 113. Published online 2024 Jan 22. doi: 10.1186/s12885-024-11855-0

PMCID:: PMC10804601

Abstract Article PDF–19M

Select item 107999037.

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun

Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0

PMCID:: PMC10799903

Abstract Article PDF–25M

Select item 106415248.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 106291859.

The characteristics and the multiple functions of integrin β1 in human cancers

Li Sun, Shuwei Guo, Yiping Xie, Yongliang Yao

J Transl Med. 2023; 21: 787. Published online 2023 Nov 6. doi: 10.1186/s12967-023-04696-1

PMCID:: PMC10629185

Abstract Article PDF–2.2M

Select item 1062778610.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 1059376311.

Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis

Weiping Xia, Xiang Chen, Zewu Zhu, Hequn Chen, Bingsheng Li, Kangning Wang, Li Huang, Zhi Liu, Zhi Chen

Sci Rep. 2023; 13: 18076. Published online 2023 Oct 23. doi: 10.1038/s41598-023-45188-y

PMCID:: PMC10593763

Abstract Article PDF–6.7M

Select item 1042528412.

TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β4

Ting-Chih Yeh, Neng-Yu Lin, Chin-Yu Chiu, Tzu-Wen Hsu, Hsin-Yi Wu, Hsuan-Yu Lin, Chi-Hau Chen, Min-Chuan Huang

Cancer Gene Ther. 2023; 30(8): 1134–1143. Published online 2023 May 23. doi: 10.1038/s41417-023-00625-y

PMCID:: PMC10425284

Abstract Article PDF–2.7M

Select item 1032325213.

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell

J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468

PMCID:: PMC10323252

Abstract Article

Select item 1023742214.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1018838815.

FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin β1 Degradation

Kamil Mieczkowski, Marta Popeda, Dagmara Lesniak, Rafal Sadej, Kamila Kitowska

J Mammary Gland Biol Neoplasia. 2023; 28(1): 9. Published online 2023 May 16. doi: 10.1007/s10911-023-09537-x

PMCID:: PMC10188388

Abstract Article PDF–1.8M

Select item 1013074816.

The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand

Yoko K Takada, Scott I Simon, Yoshikazu Takada

Life Sci Alliance. 2023 Jul; 6(7): e202201747. Published online 2023 Apr 25. doi: 10.26508/lsa.202201747

PMCID:: PMC10130748

Abstract Article PDF–3.6M

Select item 1003545117.

The WAVE2/miR-29/Integrin-β1 Oncogenic Signaling Axis Promotes Tumor Growth and Metastasis in Triple-negative Breast Cancer

Priyanka S. Rana, Wei Wang, Vesna Markovic, Justin Szpendyk, Ernest Ricky Chan, Khalid Sossey-Alaoui

Cancer Res Commun. 2023 Jan; 3(1): 160–174. Published online 2023 Jan 31. doi: 10.1158/2767-9764.CRC-22-0249

PMCID:: PMC10035451

Abstract Article PDF–16M

Select item 993913918.

ITGA5 and ITGB1 contribute to Sorafenib resistance by promoting vasculogenic mimicry formation in hepatocellular carcinoma

Ying Shi, Jin Shang, Yan Li, Deyuan Zhong, Zilong Zhang, Qinyan Yang, Chunyou Lai, Tianhang Feng, Yutong Yao, Xiaolun Huang

Cancer Med. 2023 Feb; 12(3): 3786–3796. Published online 2022 Aug 10. doi: 10.1002/cam4.5110

PMCID:: PMC9939139

Abstract Article PDF–12M

Select item 985197319.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0

PMCID:: PMC9851973

Abstract Article PDF–4.0M

Select item 983042920.

ALKBH5 activates FAK signaling through m6A demethylation in ITGB1 mRNA and enhances tumor-associated lymphangiogenesis and lymph node metastasis in ovarian cancer

Rui Sun, Lin Yuan, Yi Jiang, Yicong Wan, Xiaolling Ma, Jing Yang, Guodong Sun, Shulin Zhou, Hui Wang, Jiangnan Qiu, Lin Zhang, Wenjun Cheng

Theranostics. 2023; 13(2): 833–848. Published online 2023 Jan 5. doi: 10.7150/thno.77441

PMCID:: PMC9830429

Abstract Article PDF–8.0M

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