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Items: 1 to 20 of 58

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Lysine tRNA fragments and miR-194-5p co-regulate hepatic steatosis via β-Klotho and perilipin 2
Yonat Tzur, Katarzyna Winek, Nimrod Madrer, Serafima Dubnov, Estelle R. Bennett, David S. Greenberg, Geula Hanin, Asaad Gammal, Joseph Tam, Isaiah T. Arkin, Iddo Paldor, Hermona Soreq
Mol Metab. 2024 Jan; 79: 101856. Published online 2023 Dec 22. doi: 10.1016/j.molmet.2023.101856
PMCID:
PMC10805669
AbstractArticlePDF–2.6M
3.
Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth
Kanako Kobayashi, Kazuko Iwasa, Rika Azuma-Suzuki, Takeshi Kawauchi, Yo-ichi Nabeshima
Life Sci Alliance. 2023 Oct; 6(10): e202301916. Published online 2023 Aug 4. doi: 10.26508/lsa.202301916
PMCID:
PMC10403640
AbstractArticlePDF–2.1M
4.
Central FGF21 production regulates memory but not peripheral metabolism
Bolu Zhou, Kristin E. Claflin, Kyle H. Flippo, Andrew I. Sullivan, Arvand Asghari, Satya M. Tadinada, Sharon O. Jensen-Cody, Ted Abel, Matthew J. Potthoff
Cell Rep. Author manuscript; available in PMC 2022 Sep 14.
Published in final edited form as: Cell Rep. 2022 Aug 23; 40(8): 111239. doi: 10.1016/j.celrep.2022.111239
PMCID:
PMC9472585
AbstractArticlePDF–1.8M
5.
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury
Zhengping Hou, Qiuying Ding, Yuqi Li, Zhibo Zhao, Fang Yan, Yanping Li, Xingxing Wang, Jingyuan Xu, Weiting Chen, Guicheng Wu, Xiongzhong Ruan, Lei Zhao
eBioMedicine. 2022 Aug; 82: 104181. Published online 2022 Jul 28. doi: 10.1016/j.ebiom.2022.104181
PMCID:
PMC9352463
AbstractArticlePDF–6.2M
6.
FGF21 suppresses alcohol consumption through an amygdalo-striatal circuit
Kyle H. Flippo, Samuel A.J. Trammell, Matthew P. Gillum, Iltan Aklan, Misty B. Perez, Yavuz Yavuz, Nicholas K. Smith, Sharon O. Jensen-Cody, Bolu Zhou, Kristin E. Claflin, Amy Beierschmitt, Anders Fink-Jensen, Filip K. Knop, Roberta M. Palmour, Brad A. Grueter, Deniz Atasoy, Matthew J. Potthoff
Cell Metab. Author manuscript; available in PMC 2023 Feb 1.
Published in final edited form as: Cell Metab. 2022 Feb 1; 34(2): 317–328.e6. doi: 10.1016/j.cmet.2021.12.024
PMCID:
PMC9093612
AbstractArticlePDF–1.4M
7.
Hepatic FGF21 preserves thermoregulation and cardiovascular function during bacterial inflammation
Sarah C. Huen, Andrew Wang, Kyle Feola, Reina Desrouleaux, Harding H. Luan, Richard Hogg, Cuiling Zhang, Qing-Jun Zhang, Zhi-Ping Liu, Ruslan Medzhitov
J Exp Med. 2021 Oct 4; 218(10): e20202151. Published online 2021 Aug 18. doi: 10.1084/jem.20202151
PMCID:
PMC8374861
AbstractArticlePDF–4.3M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Glucagon receptor signaling regulates weight loss via central KLB receptor complexes
Shelly R. Nason, Jessica Antipenko, Natalie Presedo, Stephen E. Cunningham, Tanya H. Pierre, Teayoun Kim, Jodi R. Paul, Cassie Holleman, Martin E. Young, Karen L. Gamble, Brian Finan, Richard DiMarchi, Chad S. Hunter, Alexei Kharitonenkov, Kirk M. Habegger
JCI Insight. 2021 Feb 22; 6(4): e141323. Published online 2021 Feb 22. doi: 10.1172/jci.insight.141323
PMCID:
PMC7934938
AbstractArticlePDF–1.4M
10.
FGF21 Signals to Glutamatergic Neurons in the Ventromedial Hypothalamus to Suppress Carbohydrate Intake
Sharon O. Jensen-Cody, Kyle H. Flippo, Kristin E. Claflin, Yavuz Yavuz, Sarah A. Sapouckey, Grant C. Walters, Yuriy M. Usachev, Deniz Atasoy, Matthew P. Gillum, Matthew J. Potthoff
Cell Metab. Author manuscript; available in PMC 2021 Aug 4.
Published in final edited form as: Cell Metab. 2020 Aug 4; 32(2): 273–286.e6. Published online 2020 Jul 7. doi: 10.1016/j.cmet.2020.06.008
PMCID:
PMC7734879
AbstractArticlePDF–2.2M
11.
FGF21 signaling in glutamatergic neurons is required for weight loss associated with dietary protein dilution
Kyle H. Flippo, Sharon O. Jensen-Cody, Kristin E. Claflin, Matthew J. Potthoff
Sci Rep. 2020; 10: 19521. Published online 2020 Nov 11. doi: 10.1038/s41598-020-76593-2
PMCID:
PMC7658965
AbstractArticlePDF–3.6M
12.
Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy
Genaro Hernandez, Ting Luo, Tanveer A. Javed, Li Wen, Michael A. Kalwat, Kevin Vale, Farah Ammouri, Sohail Z. Husain, Steven A. Kliewer, David J. Mangelsdorf
Sci Transl Med. Author manuscript; available in PMC 2020 Jul 8.
Published in final edited form as: Sci Transl Med. 2020 Jan 8; 12(525): eaay5186. doi: 10.1126/scitranslmed.aay5186
PMCID:
PMC7034981
AbstractArticlePDF–3.2M
13.
FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism
Cristal M. Hill, Thomas Laeger, Madeleine Dehner, Diana C. Albarado, Blaise Clarke, Desiree Wanders, Susan J. Burke, J. Jason Collier, Emily Qualls-Creekmore, Samantha M. Solon-Biet, Stephen J. Simpson, Hans-Rudolf Berthoud, Heike Munzberg, Christopher D. Morrison
Cell Rep. Author manuscript; available in PMC 2019 Jun 17.
Published in final edited form as: Cell Rep. 2019 Jun 4; 27(10): 2934–2947.e3. doi: 10.1016/j.celrep.2019.05.022
PMCID:
PMC6579533
AbstractArticlePDF–1.7M
14.
Fibroblast Growth Factor-21 Controls Dietary Protein Intake in Male Mice
Karlton R Larson, Aki T-B Chaffin, Michael L Goodson, Yanbin Fang, Karen K Ryan
Endocrinology. 2019 May; 160(5): 1069–1080. Published online 2019 Feb 25. doi: 10.1210/en.2018-01056
PMCID:
PMC6469953
AbstractArticle
15.
Liver Derived FGF21 Maintains Core Body Temperature During Acute Cold Exposure
Magdalene Ameka, Kathleen R. Markan, Donald A. Morgan, Lucas D. BonDurant, Sharon O. Idiga, Meghan C. Naber, Zhiyong Zhu, Leonid V. Zingman, Justin L. Grobe, Kamal Rahmouni, Matthew J. Potthoff
Sci Rep. 2019; 9: 630. Published online 2019 Jan 24. doi: 10.1038/s41598-018-37198-y
PMCID:
PMC6345819
AbstractArticlePDF–3.2M
16.
Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation
Patricia Vázquez, Catalina Hernández-Sánchez, Carmen Escalona-Garrido, Laura Pereira, Cristina Contreras, Miguel López, Jesús Balsinde, Flora de Pablo, Ángela M. Valverde
J Lipid Res. 2018 Dec; 59(12): 2308–2320. Published online 2018 Oct 23. doi: 10.1194/jlr.M085209
PMCID:
PMC6277155
AbstractArticlePDF–1.3M
17.
The Hormone FGF21 Stimulates Water Drinking in Response to Ketogenic Diet and Alcohol
Parkyong Song, Christoph Zechner, Genaro Hernandez, José Cánovas, Yang Xie, Varun Sondhi, Martin Wagner, Vanessa Stadlbauer, Angela Horvath, Bettina Leber, Ming Chang Hu, Orson W. Moe, David J. Mangelsdorf, Steven A. Kliewer
Cell Metab. Author manuscript; available in PMC 2019 Jun 5.
Published in final edited form as: Cell Metab. 2018 Jun 5; 27(6): 1338–1347.e4. Published online 2018 Apr 12. doi: 10.1016/j.cmet.2018.04.001
PMCID:
PMC5990458
AbstractArticlePDF–1.3M
18.
Fibroblast growth factor 21 increases insulin sensitivity through specific expansion of subcutaneous fat
Huating Li, Guangyu Wu, Qichen Fang, Mingliang Zhang, Xiaoyan Hui, Bin Sheng, Liang Wu, Yuqian Bao, Peng Li, Aimin Xu, Weiping Jia
Nat Commun. 2018; 9: 272. Published online 2018 Jan 18. doi: 10.1038/s41467-017-02677-9
PMCID:
PMC5773530
AbstractArticlePDF–3.3M
19.
Fibroblast Growth Factor 21 Improves Hepatic Insulin Sensitivity by Inhibiting Mammalian Target of Rapamycin Complex 1 in Mice
Qi Gong, Zhimin Hu, Feifei Zhang, Aoyuan Cui, Xin Chen, Haoyang Jiang, Jing Gao, Xuqing Chen, Yamei Han, Qingning Liang, Dewei Ye, Lei Shi, Y. Eugene Chin, Yu Wang, Hui Xiao, Feifan Guo, Yong Liu, Mengwei Zang, Aimin Xu, Yu Li
Hepatology. Author manuscript; available in PMC 2017 Dec 12.
Published in final edited form as: Hepatology. 2016 Aug; 64(2): 425–438. Published online 2016 Apr 15. doi: 10.1002/hep.28523
PMCID:
PMC5726522
AbstractArticlePDF–1.5M
20.
FGF19, FGF21 and an FGFR1/β-Klotho-activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia
Tian Lan, Donald A. Morgan, Kamal Rahmouni, Junichiro Sonoda, Xiaorong Fu, Shawn C. Burgess, William L. Holland, Steven A. Kliewer, David J. Mangelsdorf
Cell Metab. Author manuscript; available in PMC 2018 Nov 7.
Published in final edited form as: Cell Metab. 2017 Nov 7; 26(5): 709–718.e3. Published online 2017 Oct 5. doi: 10.1016/j.cmet.2017.09.005
PMCID:
PMC5679468
AbstractArticlePDF–1.8M

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