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Select item 103116101.

SGK3 overexpression correlates with a poor prognosis in endoscopically resected superficial esophageal squamous cell neoplasia: A long-term study

Ning Xu, Long-Song Li, Hui Li, Li-Hua Zhang, Nan Zhang, Peng-Ju Wang, Ya-Xuan Cheng, Jing-Yuan Xiang, En-Qiang Linghu, Ning-Li Chai

World J Gastroenterol. 2023 Jun 21; 29(23): 3658–3667. Published online 2023 Jun 21. doi: 10.3748/wjg.v29.i23.3658

PMCID:: PMC10311610

Abstract Article PDF–2.5M

Select item 100729062.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 96175023.

MicroRNA-92a-3p Regulates Retinal Angiogenesis by Targeting SGK3 in Vascular Endothelial Cells

Yamei Cui, Ruyuan Liu, Yiwen Hong, Yishen Wang, Yanjie Zhu, Tao Wen, Jing Lu, Shudi Mao, Xiao Wang, Jianying Pan, Yan Luo

Invest Ophthalmol Vis Sci. 2022 Oct; 63(11): 19. Published online 2022 Oct 21. doi: 10.1167/iovs.63.11.19

PMCID:: PMC9617502

Abstract Article PDF–7.1M

Select item 94819334.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 85699715.

Circ_0043532 regulates miR-182/SGK3 axis to promote granulosa cell progression in polycystic ovary syndrome

Lishuang Xu, Fang Xiong, Yinyang Bai, Juxia Xiao, Yun Zhang, Jie Chen, Qiuping Li

Reprod Biol Endocrinol. 2021; 19: 167. Published online 2021 Nov 5. doi: 10.1186/s12958-021-00839-5

PMCID:: PMC8569971

Abstract Article PDF–4.4M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 75788637.

Phosphoinositide‐dependent Kinase‐1 (PDPK1) regulates serum/glucocorticoid‐regulated Kinase 3 (SGK3) for prostate cancer cell survival

Geetha Nalairndran, Azad Hassan Abdul Razack, Chun‐Wai Mai, Felicia Fei‐Lei Chung, Kok‐Keong Chan, Ling‐Wei Hii, Wei‐Meng Lim, Ivy Chung, Chee‐Onn Leong

J Cell Mol Med. 2020 Oct; 24(20): 12188–12198. Published online 2020 Sep 14. doi: 10.1111/jcmm.15876

Correction in:: J Cell Mol Med. 2020 Dec; 24(23): 14122–14124.

PMCID:: PMC7578863

Abstract Article PDF–1.1M

Select item 74273278.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 68296489.

SGK regulates pH increase and cyclin B–Cdk1 activation to resume meiosis in starfish ovarian oocytes

Enako Hosoda, Daisaku Hiraoka, Noritaka Hirohashi, Saki Omi, Takeo Kishimoto, Kazuyoshi Chiba

J Cell Biol. 2019 Nov 4; 218(11): 3612–3629. Published online 2019 Sep 19. doi: 10.1083/jcb.201812133

PMCID:: PMC6829648

Abstract Article PDF–4.2M

Select item 682468110.

Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44

Nazma Malik, Raja S. Nirujogi, Julien Peltier, Thomas Macartney, Melanie Wightman, Alan R. Prescott, Robert Gourlay, Matthias Trost, Dario R. Alessi, Athanasios Karapetsas

Biochem J. 2019 Oct 30; 476(20): 3081–3107. Prepublished online 2019 Oct 3. Published online 2019 Oct 30. doi: 10.1042/BCJ20190608

PMCID:: PMC6824681

Abstract Article PDF–15M

Select item 645882911.

Functional role of SGK3 in PI3K/Pten driven liver tumor development

Hui Cao, Zhong Xu, Jingxiao Wang, Antonio Cigliano, Maria G. Pilo, Silvia Ribback, Shu Zhang, Yu Qiao, Li Che, Rosa M. Pascale, Diego F. Calvisi, Xin Chen

BMC Cancer. 2019; 19: 343. Published online 2019 Apr 11. doi: 10.1186/s12885-019-5551-2

PMCID:: PMC6458829

Abstract Article PDF–7.7M

Select item 577304412.

INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia

Hongjun Jin, Liyuan Yang, Lu Wang, Zailin Yang, Qian Zhan, Yao Tao, Qin Zou, Yuting Tang, Jingrong Xian, Shuaishuai Zhang, Yipei Jing, Ling Zhang

J Exp Clin Cancer Res. 2018; 37: 8. Published online 2018 Jan 17. doi: 10.1186/s13046-018-0675-9

PMCID:: PMC5773044

Abstract Article PDF–2.8M

Select item 574884013.

Mechanism of activation of SGK3 by growth factors via the Class 1 and Class 3 PI3Ks

Nazma Malik, Thomas Macartney, Annika Hornberger, Karen E. Anderson, Hannah Tovell, Alan R. Prescott, Dario R. Alessi

Biochem J. 2018 Jan 15; 475(1): 117–135. Prepublished online 2017 Nov 17. Published online 2018 Jan 2. doi: 10.1042/BCJ20170650

PMCID:: PMC5748840

Abstract Article PDF–23M

Select item 565296514.

MicroRNA-144-3p suppresses tumor growth and angiogenesis by targeting SGK3 in hepatocellular carcinoma

Manya Wu, Chaoyuan Huang, Xinping Huang, Rong Liang, Yan Feng, Xiaoling Luo

Oncol Rep. 2017 Oct; 38(4): 2173–2181. Published online 2017 Aug 11. doi: 10.3892/or.2017.5900

PMCID:: PMC5652965

Abstract Article PDF–1.1M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 533838616.

SGK3 sustains ERα signaling and drives acquired aromatase inhibitor resistance through maintaining endoplasmic reticulum homeostasis

Yuanzhong Wang, Dujin Zhou, Sheryl Phung, Charles Warden, Rumana Rashid, Nymph Chan, Shiuan Chen

Proc Natl Acad Sci U S A. 2017 Feb 21; 114(8): E1500–E1508. Published online 2017 Feb 7. doi: 10.1073/pnas.1612991114

PMCID:: PMC5338386

Abstract Article PDF–1.8M

Select item 532321317.

MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways

Xin Kong, Fengchao Liu, Jian Gao

Oncotarget. 2016 Oct 4; 7(40): 66051–66060. Published online 2016 Sep 1. doi: 10.18632/oncotarget.11800

PMCID:: PMC5323213

Abstract Article PDF–4.2M

Select item 500755218.

The hVps34‐SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth

Ruzica Bago, Eeva Sommer, Pau Castel, Claire Crafter, Fiona P Bailey, Natalia Shpiro, José Baselga, Darren Cross, Patrick A Eyers, Dario R Alessi

EMBO J. 2016 Sep 1; 35(17): 1902–1922. Published online 2016 Aug 1. doi: 10.15252/embj.201693929

Correction in:: EMBO J. 2016 Oct 17; 35(20): 2263.

PMCID:: PMC5007552

Abstract Article PDF–2.0M

Select item 484876219.

Pooled‐matrix protein interaction screens using Barcode Fusion Genetics

Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth

Mol Syst Biol. 2016 Apr; 12(4): 863. Published online 2016 Apr 23. doi: 10.15252/msb.20156660

PMCID:: PMC4848762

Abstract Article PDF–2.8M

Select item 474186820.

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas

Meng Na Chi, Su Tang Guo, James S. Wilmott, Xiang Yun Guo, Xu Guang Yan, Chun Yan Wang, Xiao Ying Liu, Lei Jin, Hsin-Yi Tseng, Tao Liu, Amanda Croft, Hubert Hondermarck, Richard A. Scolyer, Chen Chen Jiang, Xu Dong Zhang

Oncotarget. 2015 Nov 24; 6(37): 39891–39907. Published online 2015 Nov 9. doi: 10.18632/oncotarget.5359

PMCID:: PMC4741868

Abstract Article PDF–4.4M

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