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Select item 109666791.

A GFP–Tcf4 reporter mouse model for monitoring effects of Apc mutations during intestinal tumorigenesis

Bruce Boman, Levy Kopelovich, Linda Siracusa, Tao Zhang, Kim Henderson, Zenobia Cofer, Arthur Buchberg, Jeremy Z. Fields, Tomas Otevrel

Mol Carcinog. Author manuscript; available in PMC 2024 Mar 27.

Published in final edited form as: Mol Carcinog. 2009 Sep; 48(9): 821–831. doi: 10.1002/mc.20526

PMCID:: PMC10966679

Article PDF–1.6M

Select item 109035352.

Paired microbiome and metabolome analyses associate bile acid changes with colorectal cancer progression

Ting Fu, Tao Huan, Gibraan Rahman, Hui Zhi, Zhenjiang Xu, Tae Gyu Oh, Jian Guo, Sally Coulter, Anupriya Tripathi, Cameron Martino, Justin L. McCarville, Qiyun Zhu, Fritz Cayabyab, Brian Low, Mingxiao He, Shipei Xing, Fernando Vargas, Ruth T. Yu, Annette Atkins, Christopher Liddle, Janelle Ayres, Manuela Raffatellu, Pieter C. Dorrestein, Michael Downes, Rob Knight, Ronald M. Evans

Cell Rep. Author manuscript; available in PMC 2024 Feb 29.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112997. Published online 2023 Aug 22. doi: 10.1016/j.celrep.2023.112997

PMCID:: PMC10903535

Article PDF–2.4M

Select item 108715173.

Keystone pathobionts associated with colorectal cancer promote oncogenic reprograming

Josh Jones, Qiaojuan Shi, Rahul R. Nath, Ilana L. Brito

PLoS One. 2024; 19(2): e0297897. Published online 2024 Feb 16. doi: 10.1371/journal.pone.0297897

PMCID:: PMC10871517

Article PDF–2.3M

Select item 108696984.

BAMLET administration via drinking water inhibits intestinal tumor development and promotes long-term health

Hien Thi Tran, Murphy Lam Yim Wan, Ines Ambite, Michele Cavalera, Mario Grossi, Jaromir Háček, Parisa Esmaeili, António N. B. M. Carneiro, Arunima Chaudhuri, Shahram Ahmadi, Catharina Svanborg

Sci Rep. 2024; 14: 3838. Published online 2024 Feb 15. doi: 10.1038/s41598-024-54040-w

PMCID:: PMC10869698

Article PDF–5.7M

Select item 108167155.

Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome

Abhimanu Pandey, Cheng Shen, Shouya Feng, Daniel Enosi Tuipulotu, Chinh Ngo, Cheng Liu, Melan Kurera, Anukriti Mathur, Shweta Venkataraman, Jing Zhang, Dipti Talaulikar, Renhua Song, Justin J.-L. Wong, Narci Teoh, Nadeem O. Kaakoush, Si Ming Man

Sci Adv. 2024 Jan 26; 10(4): eadh3409. Published online 2024 Jan 26. doi: 10.1126/sciadv.adh3409

PMCID:: PMC10816715

Article PDF–4.5M

Select item 108163226.

Endothelial Protein C Receptor and 3K3A-Activated Protein C Protect Mice from Allergic Contact Dermatitis in a Contact Hypersensitivity Model

Meilang Xue, Christopher J. Jackson, Haiyan Lin, Ruilong Zhao, Hai Po H. Liang, Hartmut Weiler, John H. Griffin, Lyn March

Int J Mol Sci. 2024 Jan; 25(2): 1255. Published online 2024 Jan 19. doi: 10.3390/ijms25021255

PMCID:: PMC10816322

Article PDF–8.0M

Select item 107237937.

Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth

Daniel Frank, Maria Bergamasco, Michael J Mlodzianoski, Andrew Kueh, Ellen Tsui, Cathrine Hall, Georgios Kastrappis, Anne Kathrin Voss, Catriona McLean, Maree Faux, Kelly L Rogers, Bang Tran, Elizabeth Vincan, David Komander, Grant Dewson, Hoanh Tran

eLife. 2023; 12: RP90796. Published online 2023 Dec 15. doi: 10.7554/eLife.90796

PMCID:: PMC10723793

Article PDF–12M

Select item 106702068.

STAT2 Controls Colorectal Tumorigenesis and Resistance to Anti-Cancer Drugs

Mircea T. Chiriac, Zsuzsanna Hracsko, Christoph Becker, Markus F. Neurath

Cancers (Basel) 2023 Nov; 15(22): 5423. Published online 2023 Nov 15. doi: 10.3390/cancers15225423

PMCID:: PMC10670206

Article PDF–10M

Select item 106653209.

Mirabegron displays anticancer effects by globally browning adipose tissues

Xiaoting Sun, Wenhai Sui, Zepeng Mu, Sisi Xie, Jinxiu Deng, Sen Li, Takahiro Seki, Jieyu Wu, Xu Jing, Xingkang He, Yangang Wang, Xiaokun Li, Yunlong Yang, Ping Huang, Minghua Ge, Yihai Cao

Nat Commun. 2023; 14: 7610. Published online 2023 Nov 22. doi: 10.1038/s41467-023-43350-8

PMCID:: PMC10665320

Article PDF–5.0M

Select item 1065112010.

Inactivation of the tumor suppressor gene Apc synergizes with H. pylori to induce DNA damage in murine gastric stem and progenitor cells

Jiazhuo He, Zuzana Nascakova, Peter Leary, Giovanni Papa, Tomas Valenta, Konrad Basler, Anne Müller

Sci Adv. 2023 Nov 17; 9(46): eadh0322. Published online 2023 Nov 15. doi: 10.1126/sciadv.adh0322

PMCID:: PMC10651120

Article PDF–1.7M

Select item 1063610511.

Selective dopamine D2 receptor deletion from Nkx6.2 expressing cells causes impaired cognitive, motivation and anxiety phenotypes in mice

Lucila Bechelli, Eugenia Tomasella, Sofia Lopez Cardoso, Martina Belmonte, Diego M. Gelman

Sci Rep. 2023; 13: 19473. Published online 2023 Nov 9. doi: 10.1038/s41598-023-46954-8

PMCID:: PMC10636105

Article PDF–3.5M

Select item 1060130912.

Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model

Yu-Han Hung, Meghan Capeling, Jonathan W. Villanueva, Matt Kanke, Michael T. Shanahan, Sha Huang, Rebecca Cubitt, Vera D. Rinaldi, John C. Schimenti, Jason R. Spence, Praveen Sethupathy

BMC Genomics. 2023; 24: 641. Published online 2023 Oct 26. doi: 10.1186/s12864-023-09743-1

PMCID:: PMC10601309

Article PDF–2.6M

Select item 1056962613.

Newly discovered genomic mutation patterns in radiation-induced small intestinal tumors of Apc^Min/+ mice

Daisuke Iizuka, Megumi Sasatani, Atsuko Ishikawa, Kazuhiro Daino, Tokuhisa Hirouchi, Kenji Kamiya

PLoS One. 2023; 18(10): e0292643. Published online 2023 Oct 12. doi: 10.1371/journal.pone.0292643

PMCID:: PMC10569626

Article PDF–2.5M

Select item 1053570614.

Akkermansia muciniphila inhibits tryptophan metabolism via the AhR/β-catenin signaling pathway to counter the progression of colorectal cancer

Lu Zhang, Qing Ji, Qian Chen, Zhenzhen Wei, Shuochuan Liu, Long Zhang, Yuli Zhang, Zan Li, Huaimin Liu, Hua Sui

Int J Biol Sci. 2023; 19(14): 4393–4410. Published online 2023 Aug 21. doi: 10.7150/ijbs.85712

PMCID:: PMC10535706

Article PDF–13M

Select item 1052702015.

Tumor-Promoting Role of GNA14 in Colon Cancer Development

Rahui Park, Seungmin Lee, Hyunjung Chin, Anh Thai-Quynh Nguyen, Daekee Lee

Cancers (Basel) 2023 Sep; 15(18): 4572. Published online 2023 Sep 15. doi: 10.3390/cancers15184572

PMCID:: PMC10527020

Article PDF–21M

Select item 1050632216.

LFA-1 knockout inhibited the tumor growth and is correlated with treg cells

Ting Niu, Zhengyang Li, Yiting Huang, Yuxiang Ye, Yilong Liu, Zhijin Ye, Lingbi Jiang, Xiaodong He, Lijing Wang, Jiangchao Li

Cell Commun Signal. 2023; 21: 233. Published online 2023 Sep 18. doi: 10.1186/s12964-023-01238-6

PMCID:: PMC10506322

Article PDF–13M

Select item 1050408217.

ASCL2 induces an immune excluded microenvironment by activating cancer-associated fibroblasts in microsatellite stable colorectal cancer

Dan Zhang, Qi-Qi Ni, Qiao-Yan Liang, Li-Ling He, Bo-Wen Qiu, Ling-Jie Zhang, Ting-Yu Mou, Chen-Chen Le, Yuan Huang, Ting-Ting Li, Shu-Yang Wang, Yan-Qing Ding, Hong-Li Jiao, Ya-Ping Ye

Oncogene. 2023; 42(38): 2841–2853. Published online 2023 Aug 17. doi: 10.1038/s41388-023-02806-3

PMCID:: PMC10504082

Article PDF–23M

Select item 1049377918.

Platelet status in cancer cachexia progression in Apc^Min/+ mice

Patrice Cunningham, Christian A. Unger, Emma A. Patton, Akyla Aiken, Alea Browne, Ella James, Ahmed K. Aladhami, Marion C. Hope 3rd, Brandon N. VanderVeen, Thomas D. Cardaci, E. Angela Murphy, Reilly T. Enos, Kandy T. Velázquez

Front Immunol. 2023; 14: 1253587. Published online 2023 Aug 28. doi: 10.3389/fimmu.2023.1253587

PMCID:: PMC10493779

Article PDF–3.1M

Select item 1048595619.

Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon

Mary Jo Talley, Diana Nardini, Lisa A. Ehrman, Q. Richard Lu, Ronald R. Waclaw

Neural Dev. 2023; 18: 5. Published online 2023 Sep 8. doi: 10.1186/s13064-023-00173-z

PMCID:: PMC10485956

Article PDF–15M

Select item 1039319320.

Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain

Vladimir Abarinov, Joshua A. Levine, Angela J. Churchill, Bryce Hopwood, Cailin S. Deiter, Michelle A. Guney, Kristen L. Wells, Jessica M. Schrunk, Yuchun Guo, Jennifer Hammelman, David K. Gifford, Mark A. Magnuson, Hynek Wichterle, Lori Sussel

Genes Dev. 2023 Jun 1; 37(11-12): 490–504. doi: 10.1101/gad.350569.123

PMCID:: PMC10393193

Article PDF–22M

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