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Items: 1 to 20 of 127

1.
PTCH1-mutant human cerebellar organoids exhibit altered neural development and recapitulate early medulloblastoma tumorigenesis
Max J. van Essen, Elizabeth J. Apsley, Joey Riepsaame, Ruijie Xu, Paul A. Northcott, Sally A. Cowley, John Jacob, Esther B. E. Becker
Dis Model Mech. 2024 Feb 1; 17(2): dmm050323. Published online 2024 Feb 27. doi: 10.1242/dmm.050323
PMCID:
PMC10924233
Article
2.
PTCH1 gene variants rs357564, rs2236405, rs2297086 and rs41313327, mRNA and tissue expression in basal cell carcinoma patients from Western Mexico
Marianela Zambrano‐Román, Jorge R. Padilla‐Gutiérrez, Yeminia Valle, José F. Muñoz‐Valle, Elizabeth Guevara‐Gutiérrez, Diana Emilia Martínez‐Fernández, Emmanuel Valdés‐Alvarado
J Clin Lab Anal. 2024 Feb; 38(3): e25010. Published online 2024 Jan 29. doi: 10.1002/jcla.25010
PMCID:
PMC10873687
ArticlePDF–1.6M
3.
肋骨分叉-基底细胞痣-颌骨囊肿综合征两家系基因序列变异分析
彭 笑, 陈 默, 王 栋, 韩 瑞, 高 廷益, 刘 亮, 刘 畅, 张 凯
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2023 Apr 25; 52(2): 223–229. Chinese. doi: 10.3724/zdxbyxb-2022-0492
PMCID:
PMC10409912
ArticlePDF–4.5M
4.
New insight into the role of PTCH1 protein in serous ovarian carcinomas
Valentina Karin-Kujundzic, Adriana Covarrubias-Pinto, Anita Skrtic, Semir Vranic, Ljiljana Serman
Int J Oncol. 2022 Dec; 61(6): 145. Published online 2022 Oct 5. doi: 10.3892/ijo.2022.5435
PMCID:
PMC9581113
ArticlePDF–2.5M
5.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
ArticlePDF–3.6M
6.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
ArticlePDF–2.9M
7.
Systematic identification of NF90 target RNAs by iCLIP analysis
Valeria Lodde, Matteo Floris, Rachel Munk, Jennifer L. Martindale, Davide Piredda, Catello Mario Panu Napodano, Francesco Cucca, Sergio Uzzau, Kotb Abdelmohsen, Myriam Gorospe, Ji Heon Noh, M. Laura Idda
Sci Rep. 2022; 12: 364. Published online 2022 Jan 10. doi: 10.1038/s41598-021-04101-1
PMCID:
PMC8748789
ArticlePDF–4.2M
8.
Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes
Maia Kinnebrew, Giovanni Luchetti, Ria Sircar, Sara Frigui, Lucrezia Vittoria Viti, Tomoki Naito, Francis Beckert, Yasunori Saheki, Christian Siebold, Arun Radhakrishnan, Rajat Rohatgi
eLife. 2021; 10: e70504. Published online 2021 Oct 26. doi: 10.7554/eLife.70504
PMCID:
PMC8654371
ArticlePDF–2.0M
9.
New insights into the GDF9-Hedgehog-GLI signaling pathway in human ovaries: from fetus to postmenopause
Parinaz Asiabi, Clara David, Alessandra Camboni, Etienne Marbaix, Marie-Madeleine Dolmans, Christiani A. Amorim
J Assist Reprod Genet. 2021 Jun; 38(6): 1387–1403. Published online 2021 Mar 26. doi: 10.1007/s10815-021-02161-w
PMCID:
PMC8266986
ArticlePDF–42M
10.
Microdeletion of 9q22.3: A patient with minimal deletion size associated with a severe phenotype
Adam D. Ewing, Seth W. Cheetham, James J. McGill, Michael Sharkey, Rick Walker, Jennifer A. West, Malcolm J. West, Kim M. Summers
Am J Med Genet A. 2021 Jul; 185(7): 2070–2083. Published online 2021 May 7. doi: 10.1002/ajmg.a.62224
PMCID:
PMC8251932
ArticlePDF–5.5M
11.
E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened
Bo Lv, Michael W. Stuck, Paurav B. Desai, Oscar A. Cabrera, Gregory J. Pazour
J Cell Biol. 2021 Sep 6; 220(9): e202010177. Published online 2021 Jun 23. doi: 10.1083/jcb.202010177
PMCID:
PMC8236919
ArticlePDF–7.4M
12.
Prevalence of medulloblastoma in basal cell nevus syndrome patients with a PTCH1 mutation
Babette J A Verkouteren, Betül Cosgun, R Jeroen Vermeulen, Marie G H C Reinders, Michel van Geel, Johan J P Gille, Klara Mosterd
Neuro Oncol. 2021 Jun; 23(6): 1035–1036. Published online 2021 Mar 17. doi: 10.1093/neuonc/noab048
PMCID:
PMC8168812
ArticlePDF–63K
13.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
ArticlePDF–2.2M
14.
Differences in RNA and microRNA Expression Between PTCH1- and SUFU-mutated Medulloblastoma
SIVAN GERSHANOV, HELEN TOLEDANO, NOMI PERNICONE, SUZANA FICHMAN, SHALOM MICHOWIZ, ALBERT PINHASOV, NITZA GOLDENBERG-COHEN, TAMAR LISTOVSKY, MALI SALMON-DIVON
Cancer Genomics Proteomics. 2021 May-Jun; 18(3): 335–347. Published online 2021 May 3. doi: 10.21873/cgp.20264
PMCID:
PMC8126327
ArticlePDF–5.7M
15.
Circular RNA circ-CCT3 promotes hepatocellular carcinoma progression by regulating the miR-1287-5p/TEAD1/PTCH1/LOX axis
Wennan Lin, Tianyu Zhang, Guoxu Ding, Liguo Hao, Bingquan Zhang, Jing Yu, Yu Pang, Feng Geng, Lan Zhan, Minglu Zhou, Qiyu Yan, Yuguang Wang, Chunlei Zheng, Hui Li
Mol Med Rep. 2021 May; 23(5): 375. Published online 2021 Mar 16. doi: 10.3892/mmr.2021.12014
PMCID:
PMC7986040
ArticlePDF–7.7M
16.
Cholesterol access in cellular membranes controls Hedgehog signaling
Arun Radhakrishnan, Rajat Rohatgi, Christian Siebold
Nat Chem Biol. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Nat Chem Biol. 2020 Dec; 16(12): 1303–1313. Published online 2020 Nov 16. doi: 10.1038/s41589-020-00678-2
PMCID:
PMC7872078
ArticlePDF–1.7M
17.
中国人群Hedgehog通路基因与非综合征型唇腭裂的亲源效应
李 文咏, 王 梦莹, 周 仁, 王 斯悦, 郑 鸿尘, 朱 洪平, 周 治波, 吴 涛, 王 红, 石 冰
Beijing Da Xue Xue Bao Yi Xue Ban. 2020 Oct 18; 52(5): 809–814. Chinese. Published online 2020 Jun 3. doi: 10.19723/j.issn.1671-167X.2020.05.003
PMCID:
PMC7653437
ArticlePDF–913K
18.
Intracardiac tumor as a rare manifestation of genetic syndromes—presentation of a family with Gorlin syndrome and a literature review
Krzysztof Szczałuba, Ewa Makuła, Anna Piórecka-Makuła, Justyna Sicińska, Małgorzata Rydzanicz, Piotr Gasperowicz, Rafał Płoski, Bożena Werner
J Appl Genet. 2020; 61(4): 559–565. Published online 2020 Sep 22. doi: 10.1007/s13353-020-00582-4
PMCID:
PMC7652740
ArticlePDF–878K
19.
Association between PTCH1 gene polymorphisms and chronic obstructive pulmonary disease susceptibility in a Chinese Han population: a case-control study
Xi Kang, Ting Guo, Lyu Liu, Shui-Zi Ding, Cheng Lei, Hong Luo
Chin Med J (Engl) 2020 Sep 5; 133(17): 2071–2077. Published online 2020 Aug 5. doi: 10.1097/CM9.0000000000000858
PMCID:
PMC7478574
ArticlePDF–398K
20.
Hedgehog Signaling: From Basic Biology to Cancer Therapy
Fujia Wu, Yu Zhang, Bo Sun, Andrew P. McMahon, Yu Wang
Cell Chem Biol. Author manuscript; available in PMC 2020 Aug 21.
Published in final edited form as: Cell Chem Biol. 2017 Mar 16; 24(3): 252–280. Published online 2017 Mar 9. doi: 10.1016/j.chembiol.2017.02.010
PMCID:
PMC7442121
ArticlePDF–1.8M

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